Lyra Therapeutics, Inc. ($LYRA) Insider Transactions

Last updated: 2026-04-03 21:06 UTC | Total transactions: 73

In the last 12 months, insiders at Lyra Therapeutics, Inc. ($LYRA) filed 73 transactions with the SEC: 15 open-market purchases totaling $17,848,416 and 16 sales totaling $555,085. Net insider sentiment: net buying.

Lyra Therapeutics, Inc. operates in the Surgical & medical instruments & apparatus industry (Industrial Applications and Services sector).

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Recent Insider Transactions

Transaction Date Insider Name Title Transaction Type Security Shares Price Shares Owned Following Total Shares Outstanding % of Owned % of Outstanding
April 1, 2026 Cavalier Jason Principal Financial Officer D Common Stock 667 $0.00 517,880.0000 1,774,882 0.13% 0.04%
April 1, 2026 Palasis Maria Principal Executive Officer D Common Stock 2000 $0.00 1,094,733.0000 1,774,882 0.18% 0.11%
Jan. 6, 2026 Cavalier Jason Chief Financial Officer S Common Stock 769 $3.36 518,547.0000 1,774,882 0.15% 0.04%
Jan. 6, 2026 Palasis Maria President & CEO S Common Stock 1702 $3.36 1,096,733.0000 1,774,882 0.15% 0.10%
Nov. 12, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 883 $4.06 17,239.0000 1,774,882 4.87% 0.05%
Nov. 11, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 4783 $4.31 161,318.0000 1,774,882 2.88% 0.27%
Nov. 11, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 537 $4.31 18,122.0000 1,774,882 2.88% 0.03%
Nov. 12, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 7862 $4.06 153,456.0000 1,774,882 4.87% 0.44%
Nov. 13, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 3213 $3.90 14,026.0000 1,774,882 18.64% 0.18%
Nov. 13, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 28597 $3.90 124,859.0000 1,774,882 18.64% 1.61%
Nov. 6, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 3247 $5.18 22,521.0000 65,880,561 12.60% 0.00%
Nov. 7, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 1993 $4.75 20,528.0000 65,880,561 8.85% 0.00%
Nov. 7, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 17746 $4.75 182,734.0000 65,880,561 8.85% 0.03%
Nov. 6, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 28902 $5.18 200,480.0000 65,880,561 12.60% 0.04%
Nov. 10, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 1869 $4.54 18,659.0000 1,774,882 9.10% 0.11%
Nov. 10, 2025 PERCEPTIVE ADVISORS LLC Not found S Common Stock 16633 $4.54 166,101.0000 1,774,882 9.10% 0.94%
Oct. 1, 2025 Palasis Maria President & CEO A Employee Stock Option (right to buy) 3667 $0.00 7,333.0000 65,880,561 100.03% 0.01%
July 10, 2025 Palasis Maria President & CEO S Common Stock 1565 $8.91 1,098,435.0000 65,880,561 0.14% 0.00%
July 10, 2025 Cavalier Jason Chief Financial Officer S Common Stock 684 $8.91 519,316.0000 65,880,561 0.13% 0.00%
May 14, 2025 snyderman nancy lynn MD Not found A Restricted Stock Units 32000 $0.00 32,000.0000 65,880,561 9999.99% 0.05%
May 14, 2025 Smith W Bradford Not found A Restricted Stock Units 32000 $0.00 32,000.0000 65,880,561 9999.99% 0.05%
May 14, 2025 MERRIFIELD C ANN Not found A Restricted Stock Units 32000 $0.00 32,000.0000 65,880,561 9999.99% 0.05%
May 14, 2025 TOBIN JAMES R Not found A Restricted Stock Units 32000 $0.00 32,000.0000 65,880,561 9999.99% 0.05%
Jan. 8, 2025 Palasis Maria President & CEO A Common Stock 800000 $0.00 1,100,000.0000 0 266.67% 0.00%
Jan. 8, 2025 Cavalier Jason Chief Financial Officer A Common Stock 420000 $0.00 520,000.0000 0 420.00% 0.00%
Dec. 9, 2024 Palasis Maria President & CEO A Employee Stock Option (right to buy) 183333 $0.00 183,333.0000 0 9999.99% 0.00%
Dec. 9, 2024 Waksal Harlan Executive Chair A Performance-based Restricted Stock Units 128333 $0.00 0.0000 0 100.00% 0.00%
Oct. 16, 2024 Palasis Maria President & CEO A Common Stock 300000 $0.00 300,000.0000 0 9999.99% 0.00%
Oct. 16, 2024 Cavalier Jason Chief Financial Officer A Common Stock 100000 $0.00 100,000.0000 0 9999.99% 0.00%
June 13, 2024 TOBIN JAMES R Not found A Stock Option 30000 $0.00 30,000.0000 0 9999.99% 0.00%
June 13, 2024 Poukalov Konstantin Not found A Stock Option 30000 $0.00 30,000.0000 0 9999.99% 0.00%
June 13, 2024 ALTMAN MICHAEL SETH Not found A Stock Option 30000 $0.00 30,000.0000 0 9999.99% 0.00%
June 13, 2024 Smith W Bradford Not found A Stock Option 30000 $0.00 30,000.0000 0 9999.99% 0.00%
June 13, 2024 MERRIFIELD C ANN Not found A Stock Option 30000 $0.00 30,000.0000 0 9999.99% 0.00%
June 13, 2024 snyderman nancy lynn MD Not found A Stock Option 30000 $0.00 30,000.0000 0 9999.99% 0.00%
March 18, 2024 Palasis Maria President & CEO A Stock Option 500000 $0.00 500,000.0000 0 9999.99% 0.00%
March 18, 2024 Waksal Harlan Executive Chair A Common Stock 275000 $0.00 536,966.0000 0 104.98% 0.00%
Jan. 30, 2024 Cavalier Jason Chief Financial Officer A Stock Options 200000 $0.00 200,000.0000 0 9999.99% 0.00%
Jan. 30, 2024 Nieman Richard Chief Medical Officer A Stock Options 200000 $0.00 200,000.0000 0 9999.99% 0.00%
Jan. 30, 2024 Bishop John E Chief Technology Officer A Stock Options 200000 $0.00 200,000.0000 0 9999.99% 0.00%
Nov. 10, 2023 Waksal Harlan Executive Chair P Common Stock 25000 $2.96 261,966.0000 0 10.55% 0.00%
June 15, 2023 Palasis Maria President & CEO A Stock Option 150000 $0.00 150,000.0000 0 9999.99% 0.00%
June 30, 2023 ANDERSON EDWARD T Not found A Stock Option 20000 $0.00 20,000.0000 0 9999.99% 0.00%
June 30, 2023 snyderman nancy lynn MD Not found A Stock Option 20000 $0.00 20,000.0000 0 9999.99% 0.00%
June 30, 2023 MERRIFIELD C ANN Not found A Stock Option 20000 $0.00 20,000.0000 0 9999.99% 0.00%
June 30, 2023 ALTMAN MICHAEL SETH Not found A Stock Option 20000 $0.00 20,000.0000 0 9999.99% 0.00%
June 30, 2023 Poukalov Konstantin Not found A Stock Option 20000 $0.00 20,000.0000 0 9999.99% 0.00%
June 30, 2023 Smith W Bradford Not found A Stock Option 20000 $0.00 20,000.0000 0 9999.99% 0.00%
June 30, 2023 TOBIN JAMES R Not found A Stock Option 20000 $0.00 20,000.0000 0 9999.99% 0.00%
June 15, 2023 Palasis Maria President & CEO A Stock Option 150000 $0.00 150,000.0000 0 9999.99% 0.00%
May 31, 2023 NBVM GP, LLC TenPercentOwner P Warrant to purchase Common Stock 601806 $0.13 601,806.0000 0 9999.99% 0.00%
May 31, 2023 ANDERSON EDWARD T Director P Common Stock 403858 $2.43 2,377,784.0000 0 20.46% 0.00%
May 31, 2023 ANDERSON EDWARD T Director P Common Stock 197946 $2.43 1,225,853.0000 0 19.26% 0.00%
May 31, 2023 ANDERSON EDWARD T Director P Common Stock 1203612 $2.43 2,640,228.0000 0 83.78% 0.00%
May 31, 2023 ANDERSON EDWARD T Director P Warrant to purchase Common Stock 201929 $0.13 201,929.0000 0 9999.99% 0.00%
May 31, 2023 ANDERSON EDWARD T Director P Warrant to purchase Common Stock 98973 $0.13 98,973.0000 0 9999.99% 0.00%
May 31, 2023 ANDERSON EDWARD T Director P Warrant to purchase Common Stock 601806 $0.13 601,806.0000 0 9999.99% 0.00%
May 31, 2023 PERCEPTIVE ADVISORS LLC Director P Common Stock 3610832 $2.49 12,757,563.0000 0 39.48% 0.00%
May 31, 2023 PERCEPTIVE ADVISORS LLC Director P Common Stock Purchase Warrant 1805416 $0.00 1,805,416.0000 0 9999.99% 0.00%
May 31, 2023 NBVM GP, LLC TenPercentOwner P Warrant to purchase Common Stock 98973 $0.13 98,973.0000 0 9999.99% 0.00%
May 31, 2023 NBVM GP, LLC TenPercentOwner P Common Stock 197946 $2.43 1,107,370.0000 0 21.77% 0.00%
May 31, 2023 NBVM GP, LLC TenPercentOwner P Common Stock 1203612 $2.43 2,521,745.0000 0 91.31% 0.00%
May 31, 2023 NBVM GP, LLC TenPercentOwner P Warrant to purchase Common Stock 201929 $0.13 201,929.0000 0 9999.99% 0.00%
May 31, 2023 NBVM GP, LLC TenPercentOwner P Common Stock 403858 $2.43 2,259,301.0000 0 21.77% 0.00%
Feb. 27, 2023 Bishop John E Chief Technology Officer A Stock Option 220000 $0.00 220,000.0000 0 9999.99% 0.00%
Jan. 31, 2023 Cavalier Jason Chief Financial Officer A Stock Option 140000 $0.00 140,000.0000 0 9999.99% 0.00%
Jan. 31, 2023 Palasis Maria President & CEO A Stock Option 250000 $0.00 250,000.0000 0 9999.99% 0.00%
Jan. 31, 2023 Nieman Richard Chief Medical Officer A Stock Option 55537 $0.00 55,537.0000 0 9999.99% 0.00%
Jan. 31, 2023 Richard Robert E. SVP, Technical Operations A Common Stock 30000 $0.00 30,000.0000 0 9999.99% 0.00%
Jan. 31, 2023 Richard Robert E. SVP, Technical Operations A Stock Option 45000 $0.00 45,000.0000 0 9999.99% 0.00%
Jan. 31, 2023 Waksal Harlan Executive Chair A Stock Option 200000 $0.00 200,000.0000 0 9999.99% 0.00%
Jan. 31, 2023 Noyes Corinne See Remarks A Stock Option 55000 $0.00 55,000.0000 0 9999.99% 0.00%
Jan. 31, 2023 Noyes Corinne See Remarks A Common Stock 36667 $0.00 36,667.0000 0 9999.99% 0.00%