In the last 12 months, insiders at BeOne Medicines Ltd. ($ONC) filed 556 transactions with the SEC: 0 open-market purchases totaling $0 and 355 sales totaling $4,264,106,426. Net insider sentiment: net selling.
BeOne Medicines Ltd. operates in the Pharmaceutical preparations industry (Life sciences sector).
Most Active Insiders
- HHLR ADVISORS, LTD. (TenPercentOwner) — 1 transaction totaling $3,568,500,000
- BAKER BROS. ADVISORS LP (Not found) — 14 transactions totaling $384,735,063
- OYLER JOHN (Chief Executive Officer) — 153 transactions totaling $171,386,063
- Wang Xiaodong (Other) — 103 transactions totaling $79,901,351
- Wu Xiaobin (President, COO & GM China) — 45 transactions totaling $67,016,086
View all SEC Filings for BeOne Medicines Ltd. (ONC).
Set Up your own filters →Recent Insider Transactions
| Transaction Date | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|
| March 11, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 133 | $213.32 | 243.0000 | 1,488,750,354 | 120.91% | 0.00% |
| March 11, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 98 | $159.03 | 341.0000 | 1,488,750,354 | 40.33% | 0.00% |
| March 11, 2026 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 341 | $300.00 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| March 11, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1430 | $0.00 | 22,490.0000 | 1,488,750,354 | 5.98% | 0.00% |
| March 11, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1729 | $0.00 | 86,684.0000 | 1,488,750,354 | 1.96% | 0.00% |
| March 11, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 110 | $194.47 | 110.0000 | 1,488,750,354 | 9999.99% | 0.00% |
| March 11, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1274 | $0.00 | 110,396.0000 | 1,488,750,354 | 1.14% | 0.00% |
| March 6, 2026 | Lee Chan Henry | SVP, General Counsel | A | Ordinary Shares | 29874 | $0.00 | 318,370.0000 | 1,488,750,354 | 10.36% | 0.00% |
| March 6, 2026 | Lee Chan Henry | SVP, General Counsel | A | Ordinary Shares | 65390 | $0.00 | 288,496.0000 | 1,488,750,354 | 29.31% | 0.00% |
| March 6, 2026 | OYLER JOHN | Chief Executive Officer | A | Ordinary Shares | 117936 | $0.00 | 51,641,269.0000 | 1,488,750,354 | 0.23% | 0.01% |
| March 6, 2026 | OYLER JOHN | Chief Executive Officer | A | Ordinary Shares | 326976 | $0.00 | 51,523,333.0000 | 1,488,750,354 | 0.64% | 0.02% |
| March 6, 2026 | Wu Xiaobin | President and COO | A | Ordinary Shares | 168922 | $0.00 | 1,137,900.0000 | 1,488,750,354 | 17.43% | 0.01% |
| March 6, 2026 | Rosenberg Aaron | Chief Financial Officer | A | Ordinary Shares | 40573 | $0.00 | 334,919.0000 | 1,488,750,354 | 13.78% | 0.00% |
| March 6, 2026 | Rosenberg Aaron | Chief Financial Officer | A | Ordinary Shares | 79014 | $0.00 | 294,346.0000 | 1,488,750,354 | 36.69% | 0.01% |
| March 6, 2026 | Wu Xiaobin | President and COO | A | Ordinary Shares | 78624 | $0.00 | 1,216,524.0000 | 1,488,750,354 | 6.91% | 0.01% |
| March 6, 2026 | Wang Lai | President, Global Head of R&D | A | Ordinary Shares | 55029 | $0.00 | 2,221,024.0000 | 1,488,750,354 | 2.54% | 0.00% |
| March 6, 2026 | Wang Lai | President, Global Head of R&D | A | Ordinary Shares | 112606 | $0.00 | 2,165,995.0000 | 1,488,750,354 | 5.48% | 0.01% |
| Feb. 4, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 6526 | $0.00 | 23,920.0000 | 1,488,750,354 | 21.43% | 0.00% |
| Feb. 4, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 8606 | $0.00 | 88,413.0000 | 1,488,750,354 | 8.87% | 0.00% |
| Feb. 4, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 6448 | $0.00 | 111,670.0000 | 1,488,750,354 | 5.46% | 0.00% |
| Feb. 4, 2026 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 664 | $348.79 | 996.0000 | 1,488,750,354 | 40.00% | 0.00% |
| Feb. 4, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 502 | $194.47 | 502.0000 | 1,488,750,354 | 9999.99% | 0.00% |
| Feb. 4, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 662 | $213.32 | 1,164.0000 | 1,488,750,354 | 131.87% | 0.00% |
| Feb. 4, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 496 | $159.03 | 1,660.0000 | 1,488,750,354 | 42.61% | 0.00% |
| Feb. 4, 2026 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 996 | $350.00 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Jan. 7, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 196 | $159.03 | 664.0000 | 1,488,750,354 | 41.88% | 0.00% |
| Jan. 7, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 2626 | $0.00 | 30,446.0000 | 1,488,750,354 | 7.94% | 0.00% |
| Jan. 7, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 3458 | $0.00 | 97,019.0000 | 1,488,750,354 | 3.44% | 0.00% |
| Jan. 7, 2026 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 2548 | $0.00 | 118,118.0000 | 1,488,750,354 | 2.11% | 0.00% |
| Jan. 7, 2026 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 664 | $331.76 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Jan. 7, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 202 | $194.47 | 202.0000 | 1,488,750,354 | 9999.99% | 0.00% |
| Jan. 7, 2026 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 266 | $213.32 | 468.0000 | 1,488,750,354 | 131.68% | 0.00% |
| Dec. 31, 2025 | Wang Lai | President, Global Head of R&D | A | Ordinary Shares | 427895 | $0.00 | 2,053,389.0000 | 1,488,750,354 | 26.32% | 0.03% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1512 | $302.31 | 17,813.0000 | 1,488,750,354 | 7.82% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1791 | $301.58 | 98,209.0000 | 1,488,750,354 | 1.79% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 6389 | $302.29 | 91,820.0000 | 1,488,750,354 | 6.51% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1896 | $303.60 | 89,924.0000 | 1,488,750,354 | 2.06% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 5829 | $304.37 | 84,095.0000 | 1,488,750,354 | 6.48% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 3940 | $305.55 | 80,155.0000 | 1,488,750,354 | 4.69% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 4949 | $306.39 | 75,206.0000 | 1,488,750,354 | 6.17% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 5118 | $307.38 | 70,088.0000 | 1,488,750,354 | 6.81% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 14163 | $308.41 | 55,925.0000 | 1,488,750,354 | 20.21% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 10650 | $309.37 | 45,275.0000 | 1,488,750,354 | 19.04% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 16318 | $310.48 | 28,957.0000 | 1,488,750,354 | 36.04% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2344 | $311.33 | 26,613.0000 | 1,488,750,354 | 8.09% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 121 | $311.93 | 26,492.0000 | 1,488,750,354 | 0.45% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 929 | $313.52 | 25,563.0000 | 1,488,750,354 | 3.51% | 0.00% |
| Dec. 15, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1194 | $314.92 | 24,369.0000 | 1,488,750,354 | 4.67% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1877 | $300.80 | 22,492.0000 | 1,488,750,354 | 7.70% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 600 | $300.98 | 21,892.0000 | 1,488,750,354 | 2.67% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2567 | $301.79 | 19,325.0000 | 1,488,750,354 | 11.73% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 7470 | $302.74 | 10,343.0000 | 1,488,750,354 | 41.94% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1633 | $303.13 | 8,710.0000 | 1,488,750,354 | 15.79% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 5442 | $303.72 | 3,268.0000 | 1,488,750,354 | 62.48% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1255 | $304.13 | 2,013.0000 | 1,488,750,354 | 38.40% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1973 | $304.36 | 40.0000 | 1,488,750,354 | 98.01% | 0.00% |
| Dec. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 40 | $305.24 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Dec. 11, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1274 | $0.00 | 120,666.0000 | 1,488,750,354 | 1.04% | 0.00% |
| Dec. 11, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1729 | $0.00 | 100,477.0000 | 1,488,750,354 | 1.69% | 0.00% |
| Dec. 11, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1313 | $0.00 | 33,072.0000 | 1,488,750,354 | 3.82% | 0.00% |
| Dec. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1274 | $0.00 | 121,940.0000 | 1,488,750,354 | 1.03% | 0.00% |
| Dec. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1729 | $0.00 | 102,206.0000 | 1,488,750,354 | 1.66% | 0.00% |
| Dec. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 1313 | $0.00 | 34,385.0000 | 1,488,750,354 | 3.68% | 0.00% |
| Dec. 11, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 332 | $325.00 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Dec. 11, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 98 | $159.03 | 332.0000 | 1,488,750,354 | 41.88% | 0.00% |
| Dec. 11, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 133 | $213.32 | 234.0000 | 1,488,750,354 | 131.68% | 0.00% |
| Dec. 11, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 101 | $194.47 | 101.0000 | 1,488,750,354 | 9999.99% | 0.00% |
| Dec. 10, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 332 | $318.28 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Dec. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 98 | $159.03 | 332.0000 | 1,488,750,354 | 41.88% | 0.00% |
| Dec. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 133 | $213.32 | 234.0000 | 1,488,750,354 | 131.68% | 0.00% |
| Dec. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 101 | $194.47 | 101.0000 | 1,488,750,354 | 9999.99% | 0.00% |
| Nov. 26, 2025 | Sanders Corazon (Corsee) D. | Director | M | Share Option (Right to Buy) | 34151 | $0.00 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Nov. 26, 2025 | Sanders Corazon (Corsee) D. | Director | S | American Depositary Shares | 804 | $342.47 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Nov. 26, 2025 | Sanders Corazon (Corsee) D. | Director | S | American Depositary Shares | 1823 | $340.20 | 804.0000 | 1,488,750,354 | 69.39% | 0.00% |
| Nov. 26, 2025 | Sanders Corazon (Corsee) D. | Director | M | American Depositary Shares | 2627 | $159.03 | 2,627.0000 | 1,488,750,354 | 9999.99% | 0.00% |
| Nov. 17, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 10 | $382.32 | 16,365.0000 | 1,488,750,354 | 0.06% | 0.00% |
| Nov. 17, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 826 | $381.19 | 16,375.0000 | 1,488,750,354 | 4.80% | 0.00% |
| Nov. 17, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 3155 | $380.23 | 17,201.0000 | 1,488,750,354 | 15.50% | 0.00% |
| Nov. 12, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 789 | $352.78 | 27,845.0000 | 1,488,750,354 | 2.76% | 0.00% |
| Nov. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 1769 | $381.05 | 16,365.0000 | 1,488,750,354 | 9.76% | 0.00% |
| Nov. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 4240 | $380.33 | 18,134.0000 | 1,488,750,354 | 18.95% | 0.00% |
| Nov. 12, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 154 | $362.07 | 22,374.0000 | 1,488,750,354 | 0.68% | 0.00% |
| Nov. 12, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 4846 | $360.10 | 22,528.0000 | 1,488,750,354 | 17.70% | 0.00% |
| Nov. 12, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 100 | $357.43 | 27,374.0000 | 1,488,750,354 | 0.36% | 0.00% |
| Nov. 12, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 120 | $355.00 | 27,474.0000 | 1,488,750,354 | 0.43% | 0.00% |
| Nov. 12, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 251 | $354.20 | 27,594.0000 | 1,488,750,354 | 0.90% | 0.00% |
| Nov. 12, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 3240 | $351.41 | 28,634.0000 | 1,488,750,354 | 10.17% | 0.00% |
| Nov. 12, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 500 | $350.44 | 31,874.0000 | 1,488,750,354 | 1.54% | 0.00% |
| Nov. 12, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 3848 | $0.00 | 123,214.0000 | 1,488,750,354 | 3.03% | 0.00% |
| Nov. 12, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 5174 | $0.00 | 103,935.0000 | 1,488,750,354 | 4.74% | 0.00% |
| Nov. 12, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 3926 | $0.00 | 35,698.0000 | 1,488,750,354 | 9.91% | 0.00% |
| Nov. 12, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 332 | $350.00 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Nov. 12, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 664 | $348.75 | 332.0000 | 1,488,750,354 | 66.67% | 0.00% |
| Nov. 12, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 296 | $159.03 | 996.0000 | 1,488,750,354 | 42.29% | 0.00% |
| Nov. 12, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 398 | $213.32 | 700.0000 | 1,488,750,354 | 131.79% | 0.00% |
| Nov. 12, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 302 | $194.47 | 302.0000 | 1,488,750,354 | 9999.99% | 0.00% |
| Nov. 12, 2025 | OYLER JOHN | Chief Executive Officer | G | Ordinary Shares | 858533 | $0.00 | 52,496,357.0000 | 1,488,750,354 | 1.61% | 0.06% |
| Nov. 11, 2025 | OYLER JOHN | Chief Executive Officer | G | Ordinary Shares | 151320 | $0.00 | 53,354,890.0000 | 1,488,750,354 | 0.28% | 0.01% |
| Nov. 7, 2025 | Wang Xiaodong | Other | G | Ordinary Shares | 424073 | $0.00 | 9,560,814.0000 | 1,488,750,354 | 4.25% | 0.03% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 4162 | $351.12 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 116493 | $0.00 | 109,109.0000 | 1,488,750,354 | 51.64% | 0.01% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 3848 | $0.00 | 127,062.0000 | 1,488,750,354 | 2.94% | 0.00% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 1112 | $350.00 | 0.0000 | 1,488,750,354 | 100.00% | 0.00% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 302 | $194.47 | 302.0000 | 1,488,750,354 | 9999.99% | 0.00% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 8961 | $213.32 | 9,263.0000 | 1,488,750,354 | 2967.22% | 0.00% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 296 | $159.03 | 9,559.0000 | 1,488,750,354 | 3.20% | 0.00% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 664 | $347.82 | 8,895.0000 | 1,488,750,354 | 6.95% | 0.00% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 4733 | $350.22 | 4,162.0000 | 1,488,750,354 | 53.21% | 0.00% |
| Oct. 8, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 3926 | $0.00 | 39,624.0000 | 1,488,750,354 | 9.01% | 0.00% |
| Sept. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 400 | $327.78 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Sept. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 4008 | $326.90 | 400.0000 | 1,368,746,793 | 90.93% | 0.00% |
| Sept. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 12446 | $326.14 | 4,408.0000 | 1,368,746,793 | 73.85% | 0.00% |
| Sept. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 6883 | $325.06 | 16,854.0000 | 1,368,746,793 | 29.00% | 0.00% |
| Sept. 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 4066 | $324.12 | 23,737.0000 | 1,368,746,793 | 14.62% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 500 | $327.93 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 3848 | $0.00 | 130,910.0000 | 1,368,746,793 | 2.86% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 23348 | $0.00 | 225,602.0000 | 1,368,746,793 | 9.38% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 88426 | $0.00 | 43,550.0000 | 1,368,746,793 | 67.00% | 0.01% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 6802 | $194.47 | 6,802.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 1796 | $213.32 | 8,598.0000 | 1,368,746,793 | 26.40% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 296 | $159.03 | 8,894.0000 | 1,368,746,793 | 3.44% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 4776 | $325.19 | 4,118.0000 | 1,368,746,793 | 53.70% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 3318 | $325.73 | 800.0000 | 1,368,746,793 | 80.57% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 300 | $326.80 | 500.0000 | 1,368,746,793 | 37.50% | 0.00% |
| Sept. 10, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 1112 | $325.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Sept. 9, 2025 | Wang Xiaodong | Other | G | Ordinary Shares | 148096 | $0.00 | 9,984,887.0000 | 1,368,746,793 | 1.46% | 0.01% |
| Sept. 9, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 5000 | $350.06 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Sept. 5, 2025 | Sanders Corazon (Corsee) D. | Director | M | Share Option (Right to Buy) | 34645 | $0.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Sept. 5, 2025 | Sanders Corazon (Corsee) D. | Director | S | American Depositary Shares | 2665 | $337.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Sept. 5, 2025 | Sanders Corazon (Corsee) D. | Director | M | American Depositary Shares | 2665 | $155.68 | 2,665.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| Sept. 2, 2025 | Ball Titus B. | Principal Accounting Officer | S | American Depositary Shares | 122 | $326.76 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 7359 | $304.37 | 36,147.0000 | 1,368,746,793 | 16.91% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 5800 | $302.45 | 47,023.0000 | 1,368,746,793 | 10.98% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 4500 | $301.49 | 52,823.0000 | 1,368,746,793 | 7.85% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 8900 | $300.33 | 57,323.0000 | 1,368,746,793 | 13.44% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | M | American Depositary Shares | 27085 | $155.68 | 66,223.0000 | 1,368,746,793 | 69.20% | 0.00% |
| Aug. 13, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 50037 | $0.00 | 134,758.0000 | 1,368,746,793 | 27.08% | 0.00% |
| Aug. 13, 2025 | Lee Chan Henry | SVP, General Counsel | M | Share Option (Right to Buy) | 56953 | $0.00 | 131,976.0000 | 1,368,746,793 | 30.15% | 0.00% |
| Aug. 13, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 3849 | $301.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Aug. 13, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 6052 | $300.19 | 2,178.0000 | 1,368,746,793 | 73.54% | 0.00% |
| Aug. 13, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 3849 | $159.03 | 8,230.0000 | 1,368,746,793 | 87.86% | 0.00% |
| Aug. 13, 2025 | Lee Chan Henry | SVP, General Counsel | M | American Depositary Shares | 4381 | $194.47 | 4,381.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| Aug. 13, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 1112 | $300.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | M | Share Option (Right to Buy) | 119340 | $0.00 | 358,046.0000 | 1,368,746,793 | 25.00% | 0.01% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | M | Share Option (Right to Buy) | 399828 | $0.00 | 309,881.0000 | 1,368,746,793 | 56.34% | 0.03% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | M | Share Option (Right to Buy) | 352105 | $0.00 | 709,709.0000 | 1,368,746,793 | 33.16% | 0.03% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | M | Share Option (Right to Buy) | 296049 | $0.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.02% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 600 | $308.03 | 16,365.0000 | 1,368,746,793 | 3.54% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 4917 | $307.43 | 16,965.0000 | 1,368,746,793 | 22.47% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 12232 | $306.26 | 21,882.0000 | 1,368,746,793 | 35.86% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 8522 | $305.48 | 34,114.0000 | 1,368,746,793 | 19.99% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 500 | $304.19 | 42,636.0000 | 1,368,746,793 | 1.16% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 6965 | $303.31 | 43,136.0000 | 1,368,746,793 | 13.90% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 5800 | $302.04 | 50,101.0000 | 1,368,746,793 | 10.38% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 400 | $300.86 | 55,901.0000 | 1,368,746,793 | 0.71% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | M | American Depositary Shares | 22773 | $174.43 | 39,138.0000 | 1,368,746,793 | 139.16% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | M | American Depositary Shares | 9180 | $159.03 | 56,301.0000 | 1,368,746,793 | 19.48% | 0.00% |
| Aug. 14, 2025 | Wu Xiaobin | President and COO | M | American Depositary Shares | 30756 | $155.68 | 47,121.0000 | 1,368,746,793 | 187.94% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 9617 | $307.38 | 16,365.0000 | 1,368,746,793 | 37.01% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 9637 | $306.74 | 25,982.0000 | 1,368,746,793 | 27.06% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 528 | $305.59 | 35,619.0000 | 1,368,746,793 | 1.46% | 0.00% |
| Aug. 13, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 3517 | $303.54 | 43,506.0000 | 1,368,746,793 | 7.48% | 0.00% |
| Aug. 1, 2025 | Rosenberg Aaron | Chief Financial Officer | S | American Depositary Shares | 1190 | $290.47 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| July 29, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 292 | $302.92 | 1,059.0000 | 1,368,746,793 | 21.61% | 0.00% |
| July 29, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 2949 | $302.00 | 1,351.0000 | 1,368,746,793 | 68.58% | 0.00% |
| July 30, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 920 | $304.60 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| July 30, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 259 | $305.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| July 29, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 800 | $304.16 | 259.0000 | 1,368,746,793 | 75.54% | 0.00% |
| July 18, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 700 | $300.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| July 9, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1553 | $254.83 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| July 9, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 10254 | $254.10 | 1,553.0000 | 1,368,746,793 | 86.85% | 0.00% |
| July 9, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 9292 | $253.18 | 11,807.0000 | 1,368,746,793 | 44.04% | 0.00% |
| July 9, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 6703 | $252.23 | 21,099.0000 | 1,368,746,793 | 24.11% | 0.00% |
| June 24, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 100 | $267.81 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 23, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 100 | $262.90 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 23, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 1028 | $260.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 23, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 1363 | $260.00 | 16,365.0000 | 1,368,746,793 | 7.69% | 0.00% |
| June 24, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 300 | $263.50 | 1,707.0000 | 1,368,746,793 | 14.95% | 0.00% |
| June 24, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1100 | $265.35 | 607.0000 | 1,368,746,793 | 64.44% | 0.00% |
| June 24, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 507 | $266.57 | 100.0000 | 1,368,746,793 | 83.53% | 0.00% |
| June 23, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 3074 | $261.57 | 100.0000 | 1,368,746,793 | 96.85% | 0.00% |
| June 16, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 1177 | $266.40 | 470.0000 | 1,368,746,793 | 71.46% | 0.00% |
| June 16, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 422 | $266.50 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 17, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1460 | $256.49 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 16, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 3680 | $266.05 | 1,460.0000 | 1,368,746,793 | 71.60% | 0.00% |
| June 17, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 630 | $250.87 | 16,365.0000 | 1,368,746,793 | 3.71% | 0.00% |
| June 16, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 100 | $266.22 | 16,995.0000 | 1,368,746,793 | 0.58% | 0.00% |
| June 16, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 1443 | $265.47 | 17,095.0000 | 1,368,746,793 | 7.78% | 0.00% |
| June 17, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 470 | $251.37 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 10, 2025 | Wang Xiaodong | Other | M | American Depositary Shares | 41760 | $6.50 | 41,760.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| June 10, 2025 | Ball Titus B. | Principal Accounting Officer | A | Ordinary Shares | 29601 | $0.00 | 73,983.0000 | 1,368,746,793 | 66.70% | 0.00% |
| June 11, 2025 | Ball Titus B. | Principal Accounting Officer | S | American Depositary Shares | 134 | $258.36 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 10, 2025 | Lee Chan Henry | SVP, General Counsel | A | Ordinary Shares | 46878 | $0.00 | 283,920.0000 | 1,368,746,793 | 19.78% | 0.00% |
| June 10, 2025 | Lee Chan Henry | SVP, General Counsel | A | Share Option (Right to Buy) | 88244 | $0.00 | 88,244.0000 | 1,368,746,793 | 9999.99% | 0.01% |
| June 10, 2025 | Rosenberg Aaron | Chief Financial Officer | A | Ordinary Shares | 63674 | $0.00 | 230,802.0000 | 1,368,746,793 | 38.10% | 0.00% |
| June 10, 2025 | Rosenberg Aaron | Chief Financial Officer | A | Share Option (Right to Buy) | 119873 | $0.00 | 119,873.0000 | 1,368,746,793 | 9999.99% | 0.01% |
| June 10, 2025 | Wang Lai | Global Head of R&D | A | Ordinary Shares | 86359 | $0.00 | 1,790,269.0000 | 1,368,746,793 | 5.07% | 0.01% |
| June 10, 2025 | Wang Lai | Global Head of R&D | A | Share Option (Right to Buy) | 162565 | $0.00 | 162,565.0000 | 1,368,746,793 | 9999.99% | 0.01% |
| June 10, 2025 | Wu Xiaobin | President and COO | A | Ordinary Shares | 123370 | $0.00 | 1,274,296.0000 | 1,368,746,793 | 10.72% | 0.01% |
| June 10, 2025 | Wu Xiaobin | President and COO | A | Share Option (Right to Buy) | 232245 | $0.00 | 232,245.0000 | 1,368,746,793 | 9999.99% | 0.02% |
| June 10, 2025 | Wang Xiaodong | Other | A | Ordinary Shares | 98696 | $0.00 | 10,159,074.0000 | 1,368,746,793 | 0.98% | 0.01% |
| June 10, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 2901 | $261.20 | 38,859.0000 | 1,368,746,793 | 6.95% | 0.00% |
| June 10, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 15878 | $262.20 | 22,981.0000 | 1,368,746,793 | 40.86% | 0.00% |
| June 10, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 16094 | $263.17 | 6,887.0000 | 1,368,746,793 | 70.03% | 0.00% |
| June 10, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 6787 | $264.08 | 100.0000 | 1,368,746,793 | 98.55% | 0.00% |
| June 10, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 100 | $264.85 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 10, 2025 | Wang Xiaodong | Other | A | Share Option (Right to Buy) | 185796 | $0.00 | 185,796.0000 | 1,368,746,793 | 9999.99% | 0.01% |
| June 10, 2025 | Wang Xiaodong | Other | M | Share Option (Right to Buy) | 542880 | $0.00 | 7.0000 | 1,368,746,793 | 100.00% | 0.04% |
| June 10, 2025 | OYLER JOHN | Chief Executive Officer | A | Ordinary Shares | 185055 | $0.00 | 54,337,157.0000 | 1,368,746,793 | 0.34% | 0.01% |
| June 10, 2025 | OYLER JOHN | Chief Executive Officer | A | Share Option (Right to Buy) | 348374 | $0.00 | 348,374.0000 | 1,368,746,793 | 9999.99% | 0.03% |
| June 10, 2025 | Yi Qingqing | Director | J | Ordinary Shares | 29614 | $0.00 | 27,326.0000 | 1,368,746,793 | 52.01% | 0.00% |
| June 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1400 | $250.84 | 3,727.0000 | 1,368,746,793 | 27.31% | 0.00% |
| June 6, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 230 | $256.79 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 6, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 600 | $250.71 | 802.0000 | 1,368,746,793 | 42.80% | 0.00% |
| June 6, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 202 | $251.89 | 600.0000 | 1,368,746,793 | 25.19% | 0.00% |
| June 6, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 300 | $253.19 | 300.0000 | 1,368,746,793 | 50.00% | 0.00% |
| June 6, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 300 | $255.30 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 6, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 400 | $250.74 | 17,899.0000 | 1,368,746,793 | 2.19% | 0.00% |
| June 6, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 500 | $251.85 | 17,399.0000 | 1,368,746,793 | 2.79% | 0.00% |
| June 6, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 400 | $253.50 | 16,999.0000 | 1,368,746,793 | 2.30% | 0.00% |
| June 6, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 400 | $255.31 | 16,599.0000 | 1,368,746,793 | 2.35% | 0.00% |
| June 6, 2025 | Wu Xiaobin | President and COO | S | American Depositary Shares | 234 | $255.77 | 16,365.0000 | 1,368,746,793 | 1.41% | 0.00% |
| June 6, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 470 | $255.78 | 230.0000 | 1,368,746,793 | 67.14% | 0.00% |
| June 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 400 | $255.74 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| June 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 927 | $254.97 | 400.0000 | 1,368,746,793 | 69.86% | 0.00% |
| June 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1000 | $253.49 | 1,327.0000 | 1,368,746,793 | 42.97% | 0.00% |
| June 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1400 | $251.88 | 2,327.0000 | 1,368,746,793 | 37.56% | 0.00% |
| May 21, 2025 | Yi Qingqing | Director | A | Share Option (Right to Buy) | 22750 | $0.00 | 22,750.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | Yi Qingqing | Director | A | Ordinary Shares | 10985 | $0.00 | 56,940.0000 | 1,368,746,793 | 23.90% | 0.00% |
| May 21, 2025 | BAKER BROS. ADVISORS LP | Not found | A | Ordinary Shares | 21970 | $0.00 | 148,071.0000 | 1,368,746,793 | 17.42% | 0.00% |
| May 21, 2025 | BAKER BROS. ADVISORS LP | Not found | A | Share Option (Right to Buy) | 45500 | $0.00 | 45,500.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | BAKER BROS. ADVISORS LP | Not found | A | Share Option (Right to Buy) | 45500 | $0.00 | 45,500.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | BAKER BROS. ADVISORS LP | Not found | A | Ordinary Shares | 21970 | $0.00 | 148,067.0000 | 1,368,746,793 | 17.42% | 0.00% |
| May 21, 2025 | HOOPER ANTHONY C | Director | A | Share Option (Right to Buy) | 22750 | $0.00 | 22,750.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | HOOPER ANTHONY C | Director | A | Ordinary Shares | 10985 | $0.00 | 64,740.0000 | 1,368,746,793 | 20.44% | 0.00% |
| May 21, 2025 | Sanders Corazon (Corsee) D. | Director | A | Share Option (Right to Buy) | 22750 | $0.00 | 22,750.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | Sanders Corazon (Corsee) D. | Director | A | Ordinary Shares | 10985 | $0.00 | 57,226.0000 | 1,368,746,793 | 23.76% | 0.00% |
| May 21, 2025 | Dugan Margaret | Director | A | Share Option (Right to Buy) | 22750 | $0.00 | 22,750.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | Dugan Margaret | Director | A | Ordinary Shares | 10985 | $0.00 | 56,940.0000 | 1,368,746,793 | 23.90% | 0.00% |
| May 21, 2025 | Riva Alessandro | Director | A | Share Option (Right to Buy) | 22750 | $0.00 | 22,750.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | Riva Alessandro | Director | A | Ordinary Shares | 10985 | $0.00 | 56,940.0000 | 1,368,746,793 | 23.90% | 0.00% |
| May 21, 2025 | BRANDICOURT OLIVIER | Director | A | Share Option (Right to Buy) | 22750 | $0.00 | 22,750.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | BRANDICOURT OLIVIER | Director | A | Ordinary Shares | 10985 | $0.00 | 27,326.0000 | 1,368,746,793 | 67.22% | 0.00% |
| May 21, 2025 | Sharp Shalini | Director | A | Share Option (Right to Buy) | 22750 | $0.00 | 22,750.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 21, 2025 | Sharp Shalini | Director | A | Ordinary Shares | 10985 | $0.00 | 19,136.0000 | 1,368,746,793 | 134.77% | 0.00% |
| May 13, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 10221 | $222.83 | 31,539.0000 | 1,368,746,793 | 24.48% | 0.00% |
| May 13, 2025 | Wang Xiaodong | Other | M | American Depositary Shares | 41760 | $6.50 | 41,760.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| May 13, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 200 | $225.68 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| May 13, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 10104 | $224.32 | 200.0000 | 1,368,746,793 | 98.06% | 0.00% |
| May 13, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 21235 | $223.41 | 10,304.0000 | 1,368,746,793 | 67.33% | 0.00% |
| May 13, 2025 | Wang Xiaodong | Other | M | Share Option (Right to Buy) | 542880 | $0.00 | 542,887.0000 | 1,368,746,793 | 50.00% | 0.04% |
| May 9, 2025 | OYLER JOHN | Chief Executive Officer | M | Ordinary Shares | 4055415 | $0.50 | 56,209,356.0000 | 1,368,746,793 | 7.78% | 0.30% |
| May 9, 2025 | OYLER JOHN | Chief Executive Officer | M | Share Option (Right to Buy) | 4055415 | $0.00 | 7.0000 | 1,368,746,793 | 100.00% | 0.30% |
| May 9, 2025 | OYLER JOHN | Chief Executive Officer | F | Ordinary Shares | 1990603 | $17.85 | 54,218,753.0000 | 1,368,746,793 | 3.54% | 0.15% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 6398 | $243.41 | 7,892.0000 | 1,368,746,793 | 44.77% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | M | American Depositary Shares | 41760 | $6.50 | 41,760.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 995 | $237.56 | 40,765.0000 | 1,368,746,793 | 2.38% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 805 | $238.48 | 39,960.0000 | 1,368,746,793 | 1.97% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | M | Share Option (Right to Buy) | 542880 | $0.00 | 1,085,767.0000 | 1,368,746,793 | 33.33% | 0.04% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 365 | $249.45 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 535 | $248.90 | 365.0000 | 1,368,746,793 | 59.44% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1475 | $247.46 | 900.0000 | 1,368,746,793 | 62.11% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1869 | $246.40 | 2,375.0000 | 1,368,746,793 | 44.04% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 2056 | $245.56 | 4,244.0000 | 1,368,746,793 | 32.63% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1592 | $244.56 | 6,300.0000 | 1,368,746,793 | 20.17% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 15041 | $242.59 | 14,290.0000 | 1,368,746,793 | 51.28% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 2229 | $241.51 | 29,331.0000 | 1,368,746,793 | 7.06% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 5516 | $240.41 | 31,560.0000 | 1,368,746,793 | 14.88% | 0.00% |
| April 14, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 2884 | $239.51 | 37,076.0000 | 1,368,746,793 | 7.22% | 0.00% |
| April 1, 2025 | Wu Xiaobin | President, COO & GM China | M | American Depositary Shares | 16477 | $119.96 | 32,842.0000 | 1,368,746,793 | 100.68% | 0.00% |
| April 1, 2025 | Wu Xiaobin | President, COO & GM China | M | American Depositary Shares | 35444 | $174.43 | 68,286.0000 | 1,368,746,793 | 107.92% | 0.00% |
| April 1, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 28253 | $280.31 | 40,033.0000 | 1,368,746,793 | 41.37% | 0.00% |
| April 1, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 6364 | $281.67 | 33,669.0000 | 1,368,746,793 | 15.90% | 0.00% |
| April 1, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 12221 | $282.76 | 21,448.0000 | 1,368,746,793 | 36.30% | 0.00% |
| April 1, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 5083 | $283.79 | 16,365.0000 | 1,368,746,793 | 23.70% | 0.00% |
| April 1, 2025 | Wu Xiaobin | President, COO & GM China | M | Share Option (Right to Buy) | 214201 | $0.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.02% |
| April 1, 2025 | Wu Xiaobin | President, COO & GM China | M | Share Option (Right to Buy) | 460772 | $0.00 | 296,049.0000 | 1,368,746,793 | 60.88% | 0.03% |
| March 18, 2025 | Wang Xiaodong | Other | M | American Depositary Shares | 41760 | $6.50 | 41,760.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| March 18, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 2417 | $258.25 | 39,343.0000 | 1,368,746,793 | 5.79% | 0.00% |
| March 18, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 6926 | $259.08 | 32,417.0000 | 1,368,746,793 | 17.60% | 0.00% |
| March 18, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 2694 | $259.86 | 29,723.0000 | 1,368,746,793 | 8.31% | 0.00% |
| March 18, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 10448 | $261.44 | 19,275.0000 | 1,368,746,793 | 35.15% | 0.00% |
| March 18, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 11245 | $262.12 | 8,030.0000 | 1,368,746,793 | 58.34% | 0.00% |
| March 18, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 6923 | $263.08 | 1,107.0000 | 1,368,746,793 | 86.21% | 0.00% |
| March 18, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1107 | $264.01 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| March 18, 2025 | Wang Xiaodong | Other | M | Share Option (Right to Buy) | 542880 | $0.00 | 1,628,647.0000 | 1,368,746,793 | 25.00% | 0.04% |
| March 14, 2025 | Wu Xiaobin | President, COO & GM China | S | RMB Shares | 0 | $0.00 | 0.0000 | 1,368,746,793 | 0.00% | 0.00% |
| March 11, 2025 | Wang Xiaodong | Other | G | Ordinary Shares | 158717 | $0.00 | 10,060,378.0000 | 1,368,746,793 | 1.55% | 0.01% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | M | Ordinary Shares | 497822 | $0.50 | 52,153,941.0000 | 1,368,746,793 | 0.96% | 0.04% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | M | American Depositary Shares | 41210 | $6.50 | 41,210.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1900 | $238.74 | 39,310.0000 | 1,368,746,793 | 4.61% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 6800 | $239.59 | 32,510.0000 | 1,368,746,793 | 17.30% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2200 | $240.70 | 30,310.0000 | 1,368,746,793 | 6.77% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 7069 | $241.92 | 23,241.0000 | 1,368,746,793 | 23.32% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 9309 | $243.04 | 13,932.0000 | 1,368,746,793 | 40.05% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 5313 | $244.04 | 8,619.0000 | 1,368,746,793 | 38.14% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 3006 | $245.19 | 5,613.0000 | 1,368,746,793 | 34.88% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 4913 | $246.11 | 700.0000 | 1,368,746,793 | 87.53% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 700 | $246.85 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| March 10, 2025 | OYLER JOHN | Chief Executive Officer | M | Share Option (Right to Buy) | 1033552 | $0.00 | 4,055,422.0000 | 1,368,746,793 | 20.31% | 0.08% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 22537 | $262.51 | 16,565.0000 | 1,368,746,793 | 57.64% | 0.00% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | M | Share Option (Right to Buy) | 91624 | $0.00 | 2.0000 | 1,368,746,793 | 100.00% | 0.01% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | M | Share Option (Right to Buy) | 583349 | $0.00 | 214,201.0000 | 1,368,746,793 | 73.14% | 0.04% |
| March 5, 2025 | Wang Lai | Global Head of R&D | A | Ordinary Shares | 69251 | $0.00 | 1,722,136.0000 | 1,368,746,793 | 4.19% | 0.01% |
| March 5, 2025 | Lee Chan Henry | SVP, General Counsel | A | Ordinary Shares | 40209 | $0.00 | 246,142.0000 | 1,368,746,793 | 19.53% | 0.00% |
| March 5, 2025 | Rosenberg Aaron | Chief Financial Officer | A | Ordinary Shares | 48581 | $0.00 | 167,128.0000 | 1,368,746,793 | 40.98% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | M | Ordinary Shares | 708747 | $0.50 | 51,656,119.0000 | 1,368,746,793 | 1.39% | 0.05% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | M | American Depositary Shares | 58590 | $6.50 | 58,590.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1400 | $246.03 | 57,190.0000 | 1,368,746,793 | 2.39% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2100 | $246.10 | 55,090.0000 | 1,368,746,793 | 3.67% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1190 | $246.69 | 53,900.0000 | 1,368,746,793 | 2.16% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 13918 | $246.91 | 39,982.0000 | 1,368,746,793 | 25.82% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 7600 | $247.99 | 32,382.0000 | 1,368,746,793 | 19.01% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 8905 | $249.04 | 23,477.0000 | 1,368,746,793 | 27.50% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 12578 | $249.97 | 10,899.0000 | 1,368,746,793 | 53.58% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2300 | $251.00 | 8,599.0000 | 1,368,746,793 | 21.10% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 3299 | $252.24 | 5,300.0000 | 1,368,746,793 | 38.36% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1100 | $253.21 | 4,200.0000 | 1,368,746,793 | 20.75% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1300 | $254.10 | 2,900.0000 | 1,368,746,793 | 30.95% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2400 | $255.02 | 500.0000 | 1,368,746,793 | 82.76% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 500 | $256.10 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| March 7, 2025 | OYLER JOHN | Chief Executive Officer | M | Share Option (Right to Buy) | 1470417 | $0.00 | 5,088,974.0000 | 1,368,746,793 | 22.42% | 0.11% |
| March 5, 2025 | OYLER JOHN | Chief Executive Officer | A | Ordinary Shares | 201084 | $0.00 | 50,461,211.0000 | 1,368,746,793 | 0.40% | 0.01% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | M | Ordinary Shares | 486161 | $0.50 | 50,947,372.0000 | 1,368,746,793 | 0.96% | 0.04% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | M | American Depositary Shares | 40109 | $6.50 | 40,109.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 3500 | $256.91 | 36,609.0000 | 1,368,746,793 | 8.73% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 13598 | $257.92 | 23,011.0000 | 1,368,746,793 | 37.14% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 8200 | $258.91 | 14,811.0000 | 1,368,746,793 | 35.64% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 6705 | $259.77 | 8,106.0000 | 1,368,746,793 | 45.27% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2906 | $261.08 | 5,200.0000 | 1,368,746,793 | 35.85% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 3400 | $262.03 | 1,800.0000 | 1,368,746,793 | 65.38% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1700 | $262.97 | 100.0000 | 1,368,746,793 | 94.44% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 100 | $264.27 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| March 6, 2025 | OYLER JOHN | Chief Executive Officer | M | Share Option (Right to Buy) | 1007578 | $0.00 | 6,559,391.0000 | 1,368,746,793 | 13.32% | 0.07% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | A | Ordinary Shares | 103883 | $0.00 | 1,175,210.0000 | 1,368,746,793 | 9.70% | 0.01% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | M | American Depositary Shares | 7048 | $169.65 | 23,413.0000 | 1,368,746,793 | 43.07% | 0.00% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | M | American Depositary Shares | 44873 | $119.96 | 68,286.0000 | 1,368,746,793 | 191.66% | 0.00% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 17824 | $260.39 | 50,462.0000 | 1,368,746,793 | 26.10% | 0.00% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 11360 | $261.61 | 39,102.0000 | 1,368,746,793 | 22.51% | 0.00% |
| March 5, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 200 | $263.00 | 16,365.0000 | 1,368,746,793 | 1.21% | 0.00% |
| March 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1214 | $255.71 | 2,132.0000 | 1,368,746,793 | 36.28% | 0.00% |
| March 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1275 | $254.77 | 3,346.0000 | 1,368,746,793 | 27.59% | 0.00% |
| March 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 700 | $251.70 | 7,446.0000 | 1,368,746,793 | 8.59% | 0.00% |
| March 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 2000 | $252.72 | 5,446.0000 | 1,368,746,793 | 26.86% | 0.00% |
| March 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 323 | $257.41 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| March 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1809 | $256.83 | 323.0000 | 1,368,746,793 | 84.85% | 0.00% |
| March 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 825 | $253.55 | 4,621.0000 | 1,368,746,793 | 15.15% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 5956 | $240.53 | 95,044.0000 | 1,368,746,793 | 5.90% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | M | American Depositary Shares | 101000 | $6.50 | 101,000.0000 | 1,368,746,793 | 9999.99% | 0.01% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | M | Ordinary Shares | 1220531 | $0.50 | 50,260,127.0000 | 1,368,746,793 | 2.49% | 0.09% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 7243 | $246.57 | 10,980.0000 | 1,368,746,793 | 39.75% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 6480 | $247.63 | 4,500.0000 | 1,368,746,793 | 59.02% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 3900 | $248.63 | 600.0000 | 1,368,746,793 | 86.67% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 600 | $249.25 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 19232 | $245.51 | 18,223.0000 | 1,368,746,793 | 51.35% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | M | Share Option (Right to Buy) | 2533531 | $0.00 | 7,566,969.0000 | 1,368,746,793 | 25.08% | 0.19% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1090 | $245.36 | 37,455.0000 | 1,368,746,793 | 2.83% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 18386 | $244.56 | 38,545.0000 | 1,368,746,793 | 32.30% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 4910 | $244.45 | 56,931.0000 | 1,368,746,793 | 7.94% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 11195 | $243.44 | 61,841.0000 | 1,368,746,793 | 15.33% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 8192 | $242.46 | 73,036.0000 | 1,368,746,793 | 10.09% | 0.00% |
| March 3, 2025 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 13816 | $241.38 | 81,228.0000 | 1,368,746,793 | 14.54% | 0.00% |
| Feb. 28, 2025 | Wu Xiaobin | President, COO & GM China | S | RMB Shares | 0 | $0.00 | 0.0000 | 1,368,746,793 | 0.00% | 0.00% |
| Feb. 27, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 1205 | $275.00 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Feb. 28, 2025 | BAKER BROS. ADVISORS LP | Not found | S | American Depositary Shares | 60851 | $260.00 | 751,478.0000 | 1,368,746,793 | 7.49% | 0.00% |
| Feb. 28, 2025 | BAKER BROS. ADVISORS LP | Not found | S | American Depositary Shares | 671976 | $260.00 | 8,089,247.0000 | 1,368,746,793 | 7.67% | 0.05% |
| Feb. 21, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 598 | $258.69 | 100.0000 | 1,368,746,793 | 85.67% | 0.00% |
| Feb. 21, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 504 | $256.84 | 698.0000 | 1,368,746,793 | 41.93% | 0.00% |
| Feb. 21, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 400 | $260.17 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Feb. 21, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 1782 | $258.73 | 400.0000 | 1,368,746,793 | 81.67% | 0.00% |
| Feb. 21, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 437 | $258.18 | 2,182.0000 | 1,368,746,793 | 16.69% | 0.00% |
| Feb. 21, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 479 | $256.70 | 2,619.0000 | 1,368,746,793 | 15.46% | 0.00% |
| Feb. 21, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 575 | $255.86 | 3,098.0000 | 1,368,746,793 | 15.65% | 0.00% |
| Feb. 21, 2025 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 1327 | $254.82 | 3,673.0000 | 1,368,746,793 | 26.54% | 0.00% |
| Feb. 21, 2025 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 100 | $260.22 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Feb. 20, 2025 | Wu Xiaobin | President, COO & GM China | M | Share Option (Right to Buy) | 276471 | $0.00 | 91,626.0000 | 1,368,746,793 | 75.11% | 0.02% |
| Feb. 18, 2025 | Wu Xiaobin | President, COO & GM China | M | American Depositary Shares | 30654 | $169.65 | 47,019.0000 | 1,368,746,793 | 187.31% | 0.00% |
| Feb. 18, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 7919 | $241.26 | 19,524.0000 | 1,368,746,793 | 28.86% | 0.00% |
| Feb. 18, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 3159 | $242.08 | 16,365.0000 | 1,368,746,793 | 16.18% | 0.00% |
| Feb. 20, 2025 | Wu Xiaobin | President, COO & GM China | M | American Depositary Shares | 21267 | $169.65 | 37,632.0000 | 1,368,746,793 | 129.95% | 0.00% |
| Feb. 20, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 21267 | $240.07 | 16,365.0000 | 1,368,746,793 | 56.51% | 0.00% |
| Feb. 18, 2025 | Wu Xiaobin | President, COO & GM China | M | Share Option (Right to Buy) | 398502 | $0.00 | 368,097.0000 | 1,368,746,793 | 51.98% | 0.03% |
| Feb. 18, 2025 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 19576 | $240.31 | 27,443.0000 | 1,368,746,793 | 41.63% | 0.00% |
| Feb. 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1519 | $224.18 | 31,142.0000 | 1,368,746,793 | 4.65% | 0.00% |
| Feb. 4, 2025 | Wang Xiaodong | Other | M | American Depositary Shares | 41760 | $6.50 | 41,760.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| Feb. 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 9099 | $223.00 | 32,661.0000 | 1,368,746,793 | 21.79% | 0.00% |
| Feb. 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 2161 | $225.27 | 28,981.0000 | 1,368,746,793 | 6.94% | 0.00% |
| Feb. 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 17805 | $226.35 | 11,176.0000 | 1,368,746,793 | 61.44% | 0.00% |
| Feb. 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 9776 | $227.00 | 1,400.0000 | 1,368,746,793 | 87.47% | 0.00% |
| Feb. 4, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1400 | $228.04 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Feb. 4, 2025 | Wang Xiaodong | Other | M | Share Option (Right to Buy) | 542880 | $0.00 | 2,171,527.0000 | 1,368,746,793 | 20.00% | 0.04% |
| Jan. 7, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 4260 | $177.42 | 6,939.0000 | 1,368,746,793 | 38.04% | 0.00% |
| Jan. 7, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 5638 | $178.39 | 1,301.0000 | 1,368,746,793 | 81.25% | 0.00% |
| Jan. 7, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 1301 | $179.18 | 0.0000 | 1,368,746,793 | 100.00% | 0.00% |
| Jan. 7, 2025 | Wang Xiaodong | Other | M | Share Option (Right to Buy) | 542880 | $0.00 | 2,714,407.0000 | 1,368,746,793 | 16.67% | 0.04% |
| Jan. 7, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 19251 | $175.46 | 22,509.0000 | 1,368,746,793 | 46.10% | 0.00% |
| Jan. 7, 2025 | Wang Xiaodong | Other | S | American Depositary Shares | 11310 | $176.67 | 11,199.0000 | 1,368,746,793 | 50.25% | 0.00% |
| Jan. 7, 2025 | Wang Xiaodong | Other | M | American Depositary Shares | 41760 | $6.50 | 41,760.0000 | 1,368,746,793 | 9999.99% | 0.00% |
| Dec. 14, 2024 | OYLER JOHN | Chief Executive Officer | M | Ordinary Shares | 1300000 | $0.50 | 49,039,596.0000 | 1,376,751,873 | 2.72% | 0.09% |
| Dec. 14, 2024 | OYLER JOHN | Chief Executive Officer | M | Share Option (Right to Buy) | 1300000 | $0.00 | 10,100,500.0000 | 1,376,751,873 | 11.40% | 0.09% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 993 | $191.78 | 2,399.0000 | 1,376,751,873 | 29.27% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 1374 | $192.61 | 1,025.0000 | 1,376,751,873 | 57.27% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 725 | $194.01 | 300.0000 | 1,376,751,873 | 70.73% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | M | Share Option (Right to Buy) | 542880 | $0.00 | 3,257,287.0000 | 1,376,751,873 | 14.29% | 0.04% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 300 | $195.67 | 0.0000 | 1,376,751,873 | 100.00% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | M | American Depositary Shares | 41760 | $6.50 | 41,760.0000 | 1,376,751,873 | 9999.99% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 2600 | $183.60 | 39,160.0000 | 1,376,751,873 | 6.23% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 7063 | $184.83 | 32,097.0000 | 1,376,751,873 | 18.04% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 9956 | $185.73 | 22,141.0000 | 1,376,751,873 | 31.02% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 9266 | $186.99 | 12,875.0000 | 1,376,751,873 | 41.85% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 6350 | $187.60 | 6,525.0000 | 1,376,751,873 | 49.32% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 1300 | $188.79 | 5,225.0000 | 1,376,751,873 | 19.92% | 0.00% |
| Dec. 10, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 1833 | $190.57 | 3,392.0000 | 1,376,751,873 | 35.08% | 0.00% |
| Dec. 6, 2024 | Wu Xiaobin | President, COO & GM China | S | RMB Shares | 0 | $0.00 | 0.0000 | 1,376,751,873 | 0.00% | 0.00% |
| Dec. 9, 2024 | BAKER BROS. ADVISORS LP | Not found | S | American Depositary Shares | 3074 | $208.01 | 895,365.0000 | 1,376,751,873 | 0.34% | 0.00% |
| Dec. 9, 2024 | BAKER BROS. ADVISORS LP | Not found | S | American Depositary Shares | 33943 | $208.01 | 9,678,187.0000 | 1,376,751,873 | 0.35% | 0.00% |
| Dec. 9, 2024 | BAKER BROS. ADVISORS LP | Not found | S | American Depositary Shares | 83036 | $186.50 | 812,329.0000 | 1,376,751,873 | 9.27% | 0.01% |
| Dec. 9, 2024 | BAKER BROS. ADVISORS LP | Not found | S | American Depositary Shares | 916964 | $186.50 | 8,761,223.0000 | 1,376,751,873 | 9.47% | 0.07% |
| Dec. 2, 2024 | HHLR ADVISORS, LTD. | TenPercentOwner | S | Ordinary Shares | 17842500 | $200.00 | 125,045,741.0000 | 1,376,751,873 | 12.49% | 1.30% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 4425 | $187.16 | 36,043.0000 | 1,376,751,873 | 10.93% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | M | American Depositary Shares | 38461 | $6.50 | 40,468.0000 | 1,376,751,873 | 1916.34% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 300 | $187.61 | 35,743.0000 | 1,376,751,873 | 0.83% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 5875 | $187.98 | 29,868.0000 | 1,376,751,873 | 16.44% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 400 | $188.55 | 29,468.0000 | 1,376,751,873 | 1.34% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 2700 | $189.17 | 26,768.0000 | 1,376,751,873 | 9.16% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 200 | $189.76 | 26,568.0000 | 1,376,751,873 | 0.75% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 6187 | $190.32 | 20,381.0000 | 1,376,751,873 | 23.29% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 700 | $191.05 | 19,681.0000 | 1,376,751,873 | 3.43% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 12293 | $191.22 | 7,388.0000 | 1,376,751,873 | 62.46% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 407 | $191.81 | 6,981.0000 | 1,376,751,873 | 5.51% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 6981 | $191.96 | 0.0000 | 1,376,751,873 | 100.00% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 1014 | $187.15 | 6,869.0000 | 1,376,751,873 | 12.86% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 1186 | $188.08 | 5,683.0000 | 1,376,751,873 | 17.27% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 600 | $189.03 | 5,083.0000 | 1,376,751,873 | 10.56% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 1475 | $190.31 | 3,608.0000 | 1,376,751,873 | 29.02% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 2725 | $191.24 | 883.0000 | 1,376,751,873 | 75.53% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | S | American Depositary Shares | 883 | $191.89 | 0.0000 | 1,376,751,873 | 100.00% | 0.00% |
| Nov. 26, 2024 | Wang Xiaodong | Other | M | Share Option (Right to Buy) | 499993 | $0.00 | 7.0000 | 1,376,751,873 | 100.00% | 0.04% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1565 | $229.25 | 4,610.0000 | 1,376,751,873 | 25.34% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1452 | $236.37 | 0.0000 | 1,376,751,873 | 100.00% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1747 | $230.05 | 2,863.0000 | 1,376,751,873 | 37.90% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 229 | $231.05 | 2,634.0000 | 1,376,751,873 | 8.00% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 38 | $233.00 | 2,596.0000 | 1,376,751,873 | 1.44% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 428 | $234.27 | 2,168.0000 | 1,376,751,873 | 16.49% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1272 | $235.41 | 896.0000 | 1,376,751,873 | 58.67% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 896 | $236.37 | 0.0000 | 1,376,751,873 | 100.00% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2535 | $229.25 | 7,465.0000 | 1,376,751,873 | 25.35% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2827 | $230.05 | 4,638.0000 | 1,376,751,873 | 37.87% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 371 | $231.04 | 4,267.0000 | 1,376,751,873 | 8.00% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 62 | $233.00 | 4,205.0000 | 1,376,751,873 | 1.45% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 694 | $234.27 | 3,511.0000 | 1,376,751,873 | 16.50% | 0.00% |
| Oct. 8, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2059 | $235.41 | 1,452.0000 | 1,376,751,873 | 58.64% | 0.00% |
| Sept. 30, 2024 | Sharp Shalini | Director | A | Ordinary Shares | 8151 | $0.00 | 8,151.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| Sept. 30, 2024 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 1202 | $237.10 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| Sept. 30, 2024 | Sharp Shalini | Director | A | Share Option (Right to Buy) | 17238 | $0.00 | 17,238.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| Sept. 27, 2024 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 5000 | $220.35 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| Sept. 19, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 4500 | $200.14 | 16,365.0000 | 1,357,034,547 | 21.57% | 0.00% |
| Sept. 17, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 500 | $200.00 | 20,865.0000 | 1,357,034,547 | 2.34% | 0.00% |
| Sept. 3, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 274 | $192.04 | 16,365.0000 | 1,357,034,547 | 1.65% | 0.00% |
| Sept. 3, 2024 | Ball Titus B. | Principal Accounting Officer | S | American Depositary Shares | 137 | $189.94 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| Sept. 3, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 2032 | $188.16 | 19,889.0000 | 1,357,034,547 | 9.27% | 0.00% |
| Sept. 3, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 275 | $188.97 | 19,614.0000 | 1,357,034,547 | 1.38% | 0.00% |
| Sept. 3, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 2275 | $190.29 | 17,339.0000 | 1,357,034,547 | 11.60% | 0.00% |
| Sept. 3, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 700 | $191.20 | 16,639.0000 | 1,357,034,547 | 4.04% | 0.00% |
| Aug. 12, 2024 | Wang Xiaodong | Other | G | Ordinary Shares | 301457 | $0.00 | 10,453,563.0000 | 1,357,034,547 | 2.80% | 0.02% |
| Aug. 9, 2024 | Rosenberg Aaron | Chief Financial Officer | A | Share Option (Right to Buy) | 220987 | $0.00 | 220,987.0000 | 1,357,034,547 | 9999.99% | 0.02% |
| Aug. 9, 2024 | Rosenberg Aaron | Chief Financial Officer | A | Ordinary Shares | 118547 | $0.00 | 118,547.0000 | 1,357,034,547 | 9999.99% | 0.01% |
| July 30, 2024 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 834 | $160.57 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| July 1, 2024 | Wang Julia Aijun | Chief Financial Officer | S | American Depositary Shares | 472 | $143.90 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| June 24, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 400 | $160.38 | 16,388.0000 | 1,357,034,547 | 2.38% | 0.00% |
| June 24, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 400 | $160.12 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| June 24, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2389 | $159.49 | 400.0000 | 1,357,034,547 | 85.66% | 0.00% |
| June 24, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 23 | $161.27 | 16,365.0000 | 1,357,034,547 | 0.14% | 0.00% |
| June 24, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 1036 | $159.53 | 16,788.0000 | 1,357,034,547 | 5.81% | 0.00% |
| June 24, 2024 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 2 | $161.10 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| June 24, 2024 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 1062 | $159.80 | 2.0000 | 1,357,034,547 | 99.81% | 0.00% |
| June 24, 2024 | Wang Julia Aijun | Chief Financial Officer | S | American Depositary Shares | 899 | $155.66 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| June 17, 2024 | Wang Julia Aijun | Chief Financial Officer | S | American Depositary Shares | 253 | $159.00 | 314.0000 | 1,357,034,547 | 44.62% | 0.00% |
| June 17, 2024 | Wang Julia Aijun | Chief Financial Officer | S | American Depositary Shares | 314 | $159.74 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| June 17, 2024 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 237 | $158.50 | 2,104.0000 | 1,357,034,547 | 10.12% | 0.00% |
| June 17, 2024 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 478 | $159.00 | 1,626.0000 | 1,357,034,547 | 22.72% | 0.00% |
| June 17, 2024 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 485 | $159.42 | 1,141.0000 | 1,357,034,547 | 29.83% | 0.00% |
| June 17, 2024 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 300 | $159.90 | 841.0000 | 1,357,034,547 | 26.29% | 0.00% |
| June 18, 2024 | Wang Lai | Global Head of R&D | S | American Depositary Shares | 841 | $153.75 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| June 17, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 627 | $159.00 | 18,992.0000 | 1,357,034,547 | 3.20% | 0.00% |
| June 18, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 1121 | $153.66 | 17,871.0000 | 1,357,034,547 | 5.90% | 0.00% |
| June 18, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 906 | $154.17 | 16,965.0000 | 1,357,034,547 | 5.07% | 0.00% |
| June 18, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 300 | $155.15 | 16,665.0000 | 1,357,034,547 | 1.77% | 0.00% |
| June 18, 2024 | Wu Xiaobin | President, COO & GM China | S | American Depositary Shares | 300 | $156.80 | 16,365.0000 | 1,357,034,547 | 1.80% | 0.00% |
| June 17, 2024 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 102 | $158.20 | 337.0000 | 1,357,034,547 | 23.23% | 0.00% |
| June 17, 2024 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 208 | $159.68 | 129.0000 | 1,357,034,547 | 61.72% | 0.00% |
| June 17, 2024 | Lee Chan Henry | SVP, General Counsel | S | American Depositary Shares | 129 | $159.74 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| June 17, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 297 | $158.53 | 984.0000 | 1,357,034,547 | 23.19% | 0.00% |
| June 17, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 608 | $159.40 | 376.0000 | 1,357,034,547 | 61.79% | 0.00% |
| June 17, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 376 | $159.91 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| June 17, 2024 | Wang Julia Aijun | Chief Financial Officer | S | American Depositary Shares | 154 | $158.24 | 762.0000 | 1,357,034,547 | 16.81% | 0.00% |
| June 17, 2024 | Wang Julia Aijun | Chief Financial Officer | S | American Depositary Shares | 195 | $158.58 | 567.0000 | 1,357,034,547 | 25.59% | 0.00% |
| June 5, 2024 | Riva Alessandro | Director | A | Share Option (Right to Buy) | 34151 | $0.00 | 34,151.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| June 5, 2024 | Wang Xiaodong | Other | A | Ordinary Shares | 108992 | $0.00 | 10,755,020.0000 | 1,357,034,547 | 1.02% | 0.01% |
| June 5, 2024 | Wang Xiaodong | Other | A | Share Option (Right to Buy) | 410657 | $0.00 | 410,657.0000 | 1,357,034,547 | 9999.99% | 0.03% |
| June 5, 2024 | Sanders Corazon (Corsee) D. | Director | A | Ordinary Shares | 16341 | $0.00 | 46,241.0000 | 1,357,034,547 | 54.65% | 0.00% |
| June 5, 2024 | Sanders Corazon (Corsee) D. | Director | A | Share Option (Right to Buy) | 34151 | $0.00 | 34,151.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| June 5, 2024 | Wang Julia Aijun | Chief Financial Officer | A | Ordinary Shares | 136240 | $0.00 | 456,326.0000 | 1,357,034,547 | 42.56% | 0.01% |
| June 5, 2024 | Dugan Margaret | Director | A | Share Option (Right to Buy) | 34151 | $0.00 | 34,151.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| June 5, 2024 | Ball Titus B. | Principal Accounting Officer | A | Ordinary Shares | 24427 | $0.00 | 47,905.0000 | 1,357,034,547 | 104.04% | 0.00% |
| June 5, 2024 | Ball Titus B. | Principal Accounting Officer | A | Share Option (Right to Buy) | 15340 | $0.00 | 15,340.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| June 5, 2024 | Wu Xiaobin | President, COO & GM China | A | Ordinary Shares | 253409 | $0.00 | 1,268,849.0000 | 1,357,034,547 | 24.96% | 0.02% |
| June 5, 2024 | Wu Xiaobin | President, COO & GM China | A | Share Option (Right to Buy) | 477386 | $0.00 | 477,386.0000 | 1,357,034,547 | 9999.99% | 0.04% |
| June 5, 2024 | Wang Lai | Global Head of R&D | A | Ordinary Shares | 168935 | $0.00 | 1,827,150.0000 | 1,357,034,547 | 10.19% | 0.01% |
| June 5, 2024 | Wang Lai | Global Head of R&D | A | Share Option (Right to Buy) | 318253 | $0.00 | 318,253.0000 | 1,357,034,547 | 9999.99% | 0.02% |
| June 5, 2024 | Lee Chan Henry | SVP, General Counsel | A | Ordinary Shares | 98085 | $0.00 | 269,399.0000 | 1,357,034,547 | 57.25% | 0.01% |
| June 5, 2024 | Lee Chan Henry | SVP, General Counsel | A | Share Option (Right to Buy) | 184795 | $0.00 | 184,795.0000 | 1,357,034,547 | 9999.99% | 0.01% |
| June 5, 2024 | Dugan Margaret | Director | A | Ordinary Shares | 16341 | $0.00 | 45,955.0000 | 1,357,034,547 | 55.18% | 0.00% |
| June 5, 2024 | Yi Qingqing | Director | A | Ordinary Shares | 16341 | $0.00 | 45,955.0000 | 1,357,034,547 | 55.18% | 0.00% |
| June 5, 2024 | BRANDICOURT OLIVIER | Director | A | Ordinary Shares | 16341 | $0.00 | 16,341.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| June 5, 2024 | BRANDICOURT OLIVIER | Director | A | Share Option (Right to Buy) | 34151 | $0.00 | 34,151.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| June 5, 2024 | HOOPER ANTHONY C | Director | A | Ordinary Shares | 16341 | $0.00 | 53,755.0000 | 1,357,034,547 | 43.68% | 0.00% |
| June 5, 2024 | HOOPER ANTHONY C | Director | A | Share Option (Right to Buy) | 34151 | $0.00 | 34,151.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| June 5, 2024 | OYLER JOHN | Chief Executive Officer | A | Ordinary Shares | 490464 | $0.00 | 48,002,781.0000 | 1,357,034,547 | 1.03% | 0.04% |
| June 5, 2024 | OYLER JOHN | Chief Executive Officer | A | Share Option (Right to Buy) | 923975 | $0.00 | 923,975.0000 | 1,357,034,547 | 9999.99% | 0.07% |
| June 5, 2024 | Glazer Donald W. | Director | A | Ordinary Shares | 16341 | $0.00 | 2,718,464.0000 | 1,357,034,547 | 0.60% | 0.00% |
| June 5, 2024 | Glazer Donald W. | Director | A | Share Option (Right to Buy) | 34151 | $0.00 | 34,151.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| June 5, 2024 | Riva Alessandro | Director | A | Ordinary Shares | 16341 | $0.00 | 45,955.0000 | 1,357,034,547 | 55.18% | 0.00% |
| June 5, 2024 | BAKER BROS. ADVISORS LP | Not found | A | Share Option (Right to Buy) | 68302 | $0.00 | 68,302.0000 | 1,357,034,547 | 9999.99% | 0.01% |
| June 5, 2024 | BAKER BROS. ADVISORS LP | Not found | A | Share Option (Right to Buy) | 68302 | $0.00 | 68,302.0000 | 1,357,034,547 | 9999.99% | 0.01% |
| June 5, 2024 | Wang Julia Aijun | Chief Financial Officer | A | Share Option (Right to Buy) | 256659 | $0.00 | 256,659.0000 | 1,357,034,547 | 9999.99% | 0.02% |
| June 5, 2024 | BAKER BROS. ADVISORS LP | Not found | A | Ordinary Shares | 32682 | $0.00 | 126,101.0000 | 1,357,034,547 | 34.98% | 0.00% |
| June 5, 2024 | BAKER BROS. ADVISORS LP | Not found | A | Ordinary Shares | 32682 | $0.00 | 126,097.0000 | 1,357,034,547 | 34.99% | 0.00% |
| June 5, 2024 | Yi Qingqing | Director | A | Share Option (Right to Buy) | 34151 | $0.00 | 34,151.0000 | 1,357,034,547 | 9999.99% | 0.00% |
| April 11, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2811 | $147.74 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| April 11, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 4265 | $146.82 | 2,811.0000 | 1,357,034,547 | 60.27% | 0.00% |
| April 11, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 5008 | $146.09 | 7,076.0000 | 1,357,034,547 | 41.44% | 0.00% |
| April 10, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 60 | $150.85 | 12,084.0000 | 1,357,034,547 | 0.49% | 0.00% |
| April 10, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2641 | $149.79 | 12,144.0000 | 1,357,034,547 | 17.86% | 0.00% |
| April 10, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 12501 | $149.15 | 14,785.0000 | 1,357,034,547 | 45.81% | 0.00% |
| April 10, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 11514 | $148.40 | 27,286.0000 | 1,357,034,547 | 29.68% | 0.00% |
| April 9, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 7924 | $154.21 | 38,800.0000 | 1,357,034,547 | 16.96% | 0.00% |
| April 9, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2734 | $153.47 | 46,724.0000 | 1,357,034,547 | 5.53% | 0.00% |
| April 9, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 542 | $152.28 | 49,458.0000 | 1,357,034,547 | 1.08% | 0.00% |
| March 12, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 6598 | $162.74 | 43,402.0000 | 1,357,034,547 | 13.20% | 0.00% |
| March 13, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 200 | $181.37 | 300.0000 | 1,357,034,547 | 40.00% | 0.00% |
| March 13, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 993 | $179.33 | 807.0000 | 1,357,034,547 | 55.17% | 0.00% |
| March 13, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 1801 | $178.10 | 1,800.0000 | 1,357,034,547 | 50.01% | 0.00% |
| March 13, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 5994 | $177.11 | 3,601.0000 | 1,357,034,547 | 62.47% | 0.00% |
| March 13, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2737 | $176.35 | 9,595.0000 | 1,357,034,547 | 22.19% | 0.00% |
| March 12, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 200 | $169.05 | 12,332.0000 | 1,357,034,547 | 1.60% | 0.00% |
| March 12, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 733 | $166.44 | 12,532.0000 | 1,357,034,547 | 5.53% | 0.00% |
| March 12, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 2602 | $165.49 | 13,265.0000 | 1,357,034,547 | 16.40% | 0.00% |
| March 12, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 12069 | $164.49 | 15,867.0000 | 1,357,034,547 | 43.20% | 0.00% |
| March 12, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 15466 | $163.78 | 27,936.0000 | 1,357,034,547 | 35.63% | 0.00% |
| March 13, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 100 | $184.17 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| March 13, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 200 | $182.63 | 100.0000 | 1,357,034,547 | 66.67% | 0.00% |
| March 13, 2024 | OYLER JOHN | Chief Executive Officer | S | American Depositary Shares | 307 | $180.26 | 500.0000 | 1,357,034,547 | 38.04% | 0.00% |
| March 11, 2024 | Glazer Donald W. | Director | G | Ordinary Shares | 82020 | $0.00 | 2,702,123.0000 | 1,357,034,547 | 2.95% | 0.01% |
| Feb. 29, 2024 | Wang Julia Aijun | Chief Financial Officer | S | American Depositary Shares | 397 | $167.08 | 0.0000 | 1,357,034,547 | 100.00% | 0.00% |
| Feb. 29, 2024 | BRANDICOURT OLIVIER | Director | A | Share Option (Right to Buy) | 27794 | $0.00 | 27,794.0000 | 1,357,034,547 | 9999.99% | 0.00% |