In the last 12 months, insiders at Olema Pharmaceuticals, Inc. ($OLMA) filed 243 transactions with the SEC: 12 open-market purchases totaling $34,037,294 and 96 sales totaling $112,524,459. Net insider sentiment: net selling.
Olema Pharmaceuticals, Inc. operates in the Pharmaceutical preparations industry (Life sciences sector).
Most Active Insiders
- Graham G. Walmsley (Director) — 12 transactions totaling $60,689,326
- Paradigm Biocapital Advisors LP (TenPercentOwner) — 3 transactions totaling $36,956,000
- BVF PARTNERS L P/IL (Director) — 6 transactions totaling $14,818,371
- Zojwalla Naseem (Chief Medical Officer) — 13 transactions totaling $9,194,540
- CLARK IAN T (Not found) — 14 transactions totaling $9,092,653
View all SEC Filings for Olema Pharmaceuticals, Inc. (OLMA).
Set Up your own filters →Recent Insider Transactions
| Transaction Date | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|
| March 4, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | S | Comon Stock | 233 | $24.69 | 0.0000 | 85,732,221 | 100.00% | 0.00% |
| March 4, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | M | Stock Option (Right to Buy) | 25000 | $0.00 | 410,000.0000 | 85,732,221 | 5.75% | 0.03% |
| March 4, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | S | Common Stock | 24767 | $24.25 | 233.0000 | 85,732,221 | 99.07% | 0.03% |
| March 3, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | M | Stock Option (Right to Buy) | 15000 | $0.00 | 435,000.0000 | 85,732,221 | 3.33% | 0.02% |
| March 3, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | M | Common Stock | 15000 | $4.37 | 15,000.0000 | 85,732,221 | 9999.99% | 0.02% |
| March 3, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | S | Common Stock | 15000 | $23.01 | 0.0000 | 85,732,221 | 100.00% | 0.02% |
| March 4, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | M | Common Stock | 25000 | $4.37 | 25,000.0000 | 85,732,221 | 9999.99% | 0.03% |
| Feb. 2, 2026 | Austin Sasha Lu | VP of Finance and Controller | A | Common Stock | 11700 | $0.00 | 16,188.0000 | 85,732,221 | 260.70% | 0.01% |
| Feb. 2, 2026 | Austin Sasha Lu | VP of Finance and Controller | A | Stock Option (Right to Buy) | 29250 | $0.00 | 29,250.0000 | 85,732,221 | 9999.99% | 0.03% |
| Feb. 2, 2026 | Bohen Sean | PRESIDENT AND CEO | A | Stock Option (Right to Buy) | 850000 | $0.00 | 850,000.0000 | 85,732,221 | 9999.99% | 0.99% |
| Feb. 2, 2026 | Bohen Sean | PRESIDENT AND CEO | A | Performance Stock Options (Right to Buy) | 275000 | $0.00 | 275,000.0000 | 85,732,221 | 9999.99% | 0.32% |
| Feb. 2, 2026 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | A | Stock Option (Right to Buy) | 250000 | $0.00 | 250,000.0000 | 85,732,221 | 9999.99% | 0.29% |
| Feb. 2, 2026 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | A | Performance Stock Options (Right to Buy) | 106250 | $0.00 | 106,250.0000 | 85,732,221 | 9999.99% | 0.12% |
| Feb. 2, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | A | Stock Option (Right to Buy) | 250000 | $0.00 | 250,000.0000 | 85,732,221 | 9999.99% | 0.29% |
| Feb. 2, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | A | Performance Stock Options (Right to Buy) | 106250 | $0.00 | 106,250.0000 | 85,732,221 | 9999.99% | 0.12% |
| Feb. 2, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | A | Stock Option (Right to Buy) | 220000 | $0.00 | 220,000.0000 | 85,732,221 | 9999.99% | 0.26% |
| Feb. 2, 2026 | Mitchell Shawnte | CHIEF LEGAL OFFICER | A | Performance Stock Options (Right to Buy) | 56250 | $0.00 | 56,250.0000 | 85,732,221 | 9999.99% | 0.07% |
| Jan. 20, 2026 | Harmon Cyrus | Not found | S | Common Stock | 10000 | $26.88 | 844,798.0000 | 85,732,221 | 1.17% | 0.01% |
| Jan. 14, 2026 | Harmon Cyrus | Not found | S | Common Stock | 3489 | $29.12 | 854,798.0000 | 85,732,221 | 0.41% | 0.00% |
| Jan. 13, 2026 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | S | Common Stock | 3822 | $28.01 | 239,727.0000 | 85,732,221 | 1.57% | 0.00% |
| Jan. 15, 2026 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | S | Common Stock | 100000 | $28.73 | 139,727.0000 | 85,732,221 | 41.71% | 0.12% |
| Jan. 14, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | M | Stock Option (Right to Buy) | 50000 | $0.00 | 50,000.0000 | 85,732,221 | 50.00% | 0.06% |
| Jan. 14, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | M | Common Stock | 50000 | $4.87 | 750,438.0000 | 85,732,221 | 7.14% | 0.06% |
| Jan. 14, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 14997 | $28.60 | 735,441.0000 | 85,732,221 | 2.00% | 0.02% |
| Jan. 14, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 35003 | $28.99 | 700,438.0000 | 85,732,221 | 4.76% | 0.04% |
| Jan. 13, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | M | Stock Option (Right to Buy) | 50000 | $0.00 | 100,000.0000 | 85,732,221 | 33.33% | 0.06% |
| Jan. 13, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 49800 | $27.60 | 700,638.0000 | 85,732,221 | 6.64% | 0.06% |
| Jan. 13, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 200 | $28.49 | 700,438.0000 | 85,732,221 | 0.03% | 0.00% |
| Jan. 12, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 10000 | $28.34 | 700,438.0000 | 85,732,221 | 1.41% | 0.01% |
| Jan. 13, 2026 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | M | Common Stock | 50000 | $4.87 | 750,438.0000 | 85,732,221 | 7.14% | 0.06% |
| Dec. 26, 2025 | Bohen Sean | President and CEO | G | Common Stock | 8500 | $0.00 | 237,650.0000 | 85,732,221 | 3.45% | 0.01% |
| Dec. 22, 2025 | Harmon Cyrus | Not found | S | Common Stock | 2881 | $28.53 | 858,287.0000 | 85,732,221 | 0.33% | 0.00% |
| Dec. 19, 2025 | CLARK IAN T | Not found | M | Stock Option (Right to Buy) | 12070 | $0.00 | 12,080.0000 | 85,732,221 | 49.98% | 0.01% |
| Dec. 19, 2025 | CLARK IAN T | Not found | M | Stock Option (Right to Buy) | 21520 | $0.00 | 0.0000 | 85,732,221 | 100.00% | 0.03% |
| Dec. 19, 2025 | CLARK IAN T | Not found | M | Stock Option (Right to Buy) | 21520 | $0.00 | 0.0000 | 85,732,221 | 100.00% | 0.03% |
| Dec. 19, 2025 | CLARK IAN T | Not found | M | Stock Option (Right to Buy) | 209690 | $0.00 | 0.0000 | 85,732,221 | 100.00% | 0.24% |
| Dec. 19, 2025 | CLARK IAN T | Not found | S | Common Stock | 41840 | $30.48 | 0.0000 | 85,732,221 | 100.00% | 0.05% |
| Dec. 19, 2025 | CLARK IAN T | Not found | S | Common Stock | 193056 | $29.71 | 41,840.0000 | 85,732,221 | 82.19% | 0.23% |
| Dec. 19, 2025 | CLARK IAN T | Not found | S | Common Stock | 29904 | $28.83 | 234,896.0000 | 85,732,221 | 11.29% | 0.03% |
| Dec. 19, 2025 | CLARK IAN T | Not found | M | Common Stock | 12070 | $4.08 | 264,800.0000 | 85,732,221 | 4.78% | 0.01% |
| Dec. 19, 2025 | CLARK IAN T | Not found | M | Common Stock | 21520 | $7.84 | 252,730.0000 | 85,732,221 | 9.31% | 0.03% |
| Dec. 19, 2025 | CLARK IAN T | Not found | M | Common Stock | 21520 | $3.61 | 231,210.0000 | 85,732,221 | 10.26% | 0.03% |
| Dec. 19, 2025 | CLARK IAN T | Not found | M | Common Stock | 209690 | $4.41 | 209,690.0000 | 85,732,221 | 9999.99% | 0.24% |
| Dec. 23, 2025 | Zojwalla Naseem | Chief Medical Officer | M | Stock Option (Right to Buy) | 50000 | $0.00 | 156,818.0000 | 85,732,221 | 24.18% | 0.06% |
| Dec. 22, 2025 | Zojwalla Naseem | Chief Medical Officer | M | Stock Option (Right to Buy) | 7182 | $0.00 | 206,818.0000 | 85,732,221 | 3.36% | 0.01% |
| Dec. 22, 2025 | Zojwalla Naseem | Chief Medical Officer | M | Stock Option (Right to Buy) | 42818 | $0.00 | 112,182.0000 | 85,732,221 | 27.62% | 0.05% |
| Dec. 19, 2025 | Zojwalla Naseem | Chief Medical Officer | M | Stock Option (Right to Buy) | 40000 | $0.00 | 155,000.0000 | 85,732,221 | 20.51% | 0.05% |
| Dec. 23, 2025 | Zojwalla Naseem | Chief Medical Officer | S | Common Stock | 99509 | $27.66 | 4,488.0000 | 85,732,221 | 95.68% | 0.12% |
| Dec. 23, 2025 | Zojwalla Naseem | Chief Medical Officer | M | Common Stock | 50000 | $7.02 | 103,997.0000 | 85,732,221 | 92.60% | 0.06% |
| Dec. 22, 2025 | Zojwalla Naseem | Chief Medical Officer | S | Common Stock | 100000 | $28.04 | 53,997.0000 | 85,732,221 | 64.94% | 0.12% |
| Dec. 22, 2025 | Zojwalla Naseem | Chief Medical Officer | M | Common Stock | 7182 | $7.02 | 153,997.0000 | 85,732,221 | 4.89% | 0.01% |
| Dec. 22, 2025 | Zojwalla Naseem | Chief Medical Officer | M | Common Stock | 42818 | $15.25 | 146,815.0000 | 85,732,221 | 41.17% | 0.05% |
| Dec. 19, 2025 | Zojwalla Naseem | Chief Medical Officer | S | Common Stock | 12921 | $28.93 | 103,997.0000 | 85,732,221 | 11.05% | 0.02% |
| Dec. 19, 2025 | Zojwalla Naseem | Chief Medical Officer | S | Common Stock | 57079 | $28.03 | 116,918.0000 | 85,732,221 | 32.80% | 0.07% |
| Dec. 19, 2025 | Zojwalla Naseem | Chief Medical Officer | M | Common Stock | 40000 | $15.25 | 173,997.0000 | 85,732,221 | 29.85% | 0.05% |
| Dec. 19, 2025 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | G | Common Stock | 9000 | $0.00 | 710,558.0000 | 85,732,221 | 1.25% | 0.01% |
| Dec. 19, 2025 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 6046 | $31.39 | 719,558.0000 | 85,732,221 | 0.83% | 0.01% |
| Dec. 19, 2025 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 43729 | $30.40 | 725,604.0000 | 85,732,221 | 5.68% | 0.05% |
| Dec. 19, 2025 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 1225 | $28.08 | 769,333.0000 | 85,732,221 | 0.16% | 0.00% |
| Dec. 8, 2025 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | G | Common Stock | 75000 | $0.00 | 243,549.0000 | 85,732,221 | 23.54% | 0.09% |
| Nov. 26, 2025 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | G | Common Stock | 225000 | $0.00 | 318,549.0000 | 85,732,221 | 41.39% | 0.26% |
| Nov. 21, 2025 | RAPPAPORT ANDREW | Not found | M | Stock Option (right to buy) | 35868 | $0.00 | 0.0000 | 85,732,221 | 100.00% | 0.04% |
| Nov. 21, 2025 | RAPPAPORT ANDREW | Not found | M | Common Stock | 35868 | $0.39 | 421,833.0000 | 85,732,221 | 9.29% | 0.04% |
| Nov. 25, 2025 | RAPPAPORT ANDREW | Not found | G | Common Stock | 35868 | $0.00 | 385,965.0000 | 85,732,221 | 8.50% | 0.04% |
| Sept. 16, 2025 | Harmon Cyrus | Not found | S | Common Stock | 10000 | $8.04 | 871,168.0000 | 58,743,522 | 1.13% | 0.02% |
| Sept. 16, 2025 | Harmon Cyrus | Not found | S | Common Stock | 1914 | $8.08 | 864,254.0000 | 58,743,522 | 0.22% | 0.00% |
| Sept. 18, 2025 | Harmon Cyrus | Not found | S | Common Stock | 3086 | $8.32 | 861,168.0000 | 58,743,522 | 0.36% | 0.01% |
| Sept. 18, 2025 | Harmon Cyrus | Not found | S | Common Stock | 10000 | $8.33 | 861,168.0000 | 58,743,522 | 1.15% | 0.02% |
| June 11, 2025 | BUTITTA CYNTHIA M | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| June 11, 2025 | Graham G. Walmsley | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| June 11, 2025 | Hrustanovic Gorjan | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| June 11, 2025 | BVF PARTNERS L P/IL | Other | A | Stock Option (Right to buy) | 24150 | $0.00 | 176,270.0000 | 58,743,522 | 15.88% | 0.04% |
| June 11, 2025 | CLARK IAN T | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| June 11, 2025 | Horning Sandra | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| June 11, 2025 | Garland J. Scott | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| June 11, 2025 | Larson Yi | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| June 11, 2025 | RAPPAPORT ANDREW | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| June 11, 2025 | Harmon Cyrus | Not found | A | Stock Option (right to buy) | 24150 | $0.00 | 24,150.0000 | 58,743,522 | 9999.99% | 0.04% |
| Feb. 28, 2025 | Bohen Sean | PRESIDENT AND CEO | A | Stock Option (Right to Buy) | 650000 | $0.00 | 650,000.0000 | 58,743,522 | 9999.99% | 1.11% |
| Feb. 28, 2025 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | A | Stock Option (Right to Buy) | 320000 | $0.00 | 320,000.0000 | 58,743,522 | 9999.99% | 0.54% |
| Feb. 28, 2025 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | A | Stock Option (Right to Buy) | 205000 | $0.00 | 205,000.0000 | 58,743,522 | 9999.99% | 0.35% |
| Feb. 28, 2025 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | A | Stock Option (Right to Buy) | 205000 | $0.00 | 205,000.0000 | 58,743,522 | 9999.99% | 0.35% |
| Feb. 28, 2025 | Mitchell Shawnte | CHIEF LEGAL OFFICER | A | Stock Option (Right to Buy) | 450000 | $0.00 | 450,000.0000 | 58,743,522 | 9999.99% | 0.77% |
| Jan. 10, 2025 | BVF PARTNERS L P/IL | Other | D | Common stock, $0.0001 par value | 161810 | $0.00 | 2,103,522.0000 | 58,743,522 | 7.14% | 0.28% |
| Jan. 10, 2025 | BVF PARTNERS L P/IL | Other | D | Common stock, $0.0001 par value | 22740 | $0.00 | 447,526.0000 | 58,743,522 | 4.84% | 0.04% |
| Jan. 10, 2025 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 235450 | $0.00 | 3,291,004.0000 | 58,743,522 | 7.71% | 0.40% |
| Jan. 10, 2025 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 22740 | $0.00 | 336,288.0000 | 58,743,522 | 7.25% | 0.04% |
| Jan. 10, 2025 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 161810 | $0.00 | 2,627,590.0000 | 58,743,522 | 6.56% | 0.28% |
| Jan. 10, 2025 | BVF PARTNERS L P/IL | Other | D | Common stock, $0.0001 par value | 235450 | $0.00 | 2,755,533.0000 | 58,743,522 | 7.87% | 0.40% |
| Jan. 10, 2025 | Bain Capital Life Sciences Investors, LLC | Not found | J | Common Stock | 3500000 | $0.00 | 4,300,000.0000 | 58,743,522 | 44.87% | 5.96% |
| Jan. 10, 2025 | Bain Capital Life Sciences Investors, LLC | Not found | J | Pre-Funded Warrant (right to buy) | 3500000 | $0.00 | 3,500,000.0000 | 58,743,522 | 9999.99% | 5.96% |
| Jan. 8, 2025 | Bain Capital Life Sciences Investors, LLC | Not found | P | Common Stock | 300000 | $5.76 | 7,800,000.0000 | 58,743,522 | 4.00% | 0.51% |
| Dec. 13, 2024 | Graham G. Walmsley | Director | P | Common Stock | 700761 | $6.75 | 1,408,875.0000 | 57,262,803 | 98.96% | 1.22% |
| Dec. 13, 2024 | Graham G. Walmsley | Director | S | Common Stock | 700761 | $6.75 | 708,114.0000 | 57,262,803 | 49.74% | 1.22% |
| Dec. 17, 2024 | Graham G. Walmsley | Director | P | Common Stock | 700761 | $6.75 | 1,408,875.0000 | 57,262,803 | 33.22% | 1.22% |
| Dec. 16, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Stock Option (Right to Buy) | 14000 | $0.00 | 112,840.0000 | 57,262,803 | 11.04% | 0.02% |
| Dec. 16, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Common Stock | 14000 | $4.87 | 129,509.0000 | 57,262,803 | 12.12% | 0.02% |
| Dec. 17, 2024 | Graham G. Walmsley | Director | S | Common Stock | 700761 | $6.75 | 0.0000 | 57,262,803 | 100.00% | 1.22% |
| Dec. 9, 2024 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | A | Common Stock | 48750 | $0.00 | 792,076.0000 | 57,262,803 | 6.56% | 0.09% |
| Dec. 9, 2024 | Harmon Cyrus | Not found | A | Common Stock | 29250 | $0.00 | 902,561.0000 | 57,262,803 | 3.35% | 0.05% |
| Dec. 10, 2024 | Harmon Cyrus | Not found | S | Common Stock | 8256 | $9.37 | 894,305.0000 | 57,262,803 | 0.91% | 0.01% |
| Dec. 11, 2024 | Harmon Cyrus | Not found | S | Common Stock | 7958 | $8.66 | 886,347.0000 | 57,262,803 | 0.89% | 0.01% |
| Dec. 11, 2024 | Harmon Cyrus | Not found | S | Common Stock | 179 | $9.39 | 886,168.0000 | 57,262,803 | 0.02% | 0.00% |
| Dec. 10, 2024 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 12452 | $9.38 | 779,624.0000 | 57,262,803 | 1.57% | 0.02% |
| Dec. 11, 2024 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 13314 | $8.66 | 766,310.0000 | 57,262,803 | 1.71% | 0.02% |
| Dec. 11, 2024 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 300 | $9.39 | 766,010.0000 | 57,262,803 | 0.04% | 0.00% |
| Dec. 9, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | A | Common Stock | 52000 | $0.00 | 143,314.0000 | 57,262,803 | 56.95% | 0.09% |
| Dec. 10, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | S | Common Stock | 13283 | $9.37 | 130,031.0000 | 57,262,803 | 9.27% | 0.02% |
| Dec. 11, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | S | Common Stock | 14202 | $8.66 | 115,829.0000 | 57,262,803 | 10.92% | 0.02% |
| Dec. 11, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | S | Common Stock | 320 | $9.39 | 115,509.0000 | 57,262,803 | 0.28% | 0.00% |
| Dec. 9, 2024 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | A | Common Stock | 68250 | $0.00 | 578,708.0000 | 57,262,803 | 13.37% | 0.12% |
| Dec. 10, 2024 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | S | Common Stock | 16803 | $9.37 | 561,905.0000 | 57,262,803 | 2.90% | 0.03% |
| Dec. 11, 2024 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | S | Common Stock | 17950 | $8.66 | 543,955.0000 | 57,262,803 | 3.19% | 0.03% |
| Dec. 11, 2024 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | S | Common Stock | 406 | $9.39 | 543,549.0000 | 57,262,803 | 0.07% | 0.00% |
| Dec. 9, 2024 | Bohen Sean | PRESIDENT AND CEO | A | Common Stock | 204750 | $0.00 | 351,164.0000 | 57,262,803 | 139.84% | 0.36% |
| Dec. 10, 2024 | Bohen Sean | PRESIDENT AND CEO | S | Common Stock | 52328 | $9.37 | 298,836.0000 | 57,262,803 | 14.90% | 0.09% |
| Dec. 11, 2024 | Bohen Sean | PRESIDENT AND CEO | S | Common Stock | 55907 | $8.66 | 242,929.0000 | 57,262,803 | 18.71% | 0.10% |
| Dec. 11, 2024 | Bohen Sean | PRESIDENT AND CEO | S | Common Stock | 1267 | $9.39 | 241,662.0000 | 57,262,803 | 0.52% | 0.00% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 1258027 | $9.08 | 3,055,554.0000 | 57,262,803 | 69.99% | 2.20% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | D | Common stock, $0.0001 par value | 1797527 | $0.00 | 2,990,983.0000 | 57,262,803 | 37.54% | 3.14% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 160107 | $9.08 | 313,548.0000 | 57,262,803 | 104.34% | 0.28% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 1047044 | $9.08 | 2,465,780.0000 | 57,262,803 | 73.80% | 1.83% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | D | Common stock, $0.0001 par value | 1418736 | $0.00 | 2,265,332.0000 | 57,262,803 | 38.51% | 2.48% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 1418736 | $0.00 | 1,418,736.0000 | 57,262,803 | 9999.99% | 2.48% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 153441 | $0.00 | 153,441.0000 | 57,262,803 | 9999.99% | 0.27% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | D | Common stock, $0.0001 par value | 153441 | $0.00 | 470,266.0000 | 57,262,803 | 24.60% | 0.27% |
| Dec. 4, 2024 | BVF PARTNERS L P/IL | Other | A | Pre-Funded Warrant | 1797527 | $0.00 | 1,797,527.0000 | 57,262,803 | 9999.99% | 3.14% |
| June 4, 2024 | Graham G. Walmsley | Director | S | Common Stock | 475000 | $14.85 | 708,114.0000 | 45,247,098 | 40.15% | 1.05% |
| June 4, 2024 | Graham G. Walmsley | Director | S | Common Stock | 700000 | $14.85 | 700,761.0000 | 45,247,098 | 49.97% | 1.55% |
| Nov. 15, 2024 | Kovacs Shane William Charles | Ch. Operating & Financial Off. | M | Common Stock | 25000 | $7.02 | 510,458.0000 | 57,262,803 | 5.15% | 0.04% |
| Nov. 15, 2024 | Kovacs Shane William Charles | Ch. Operating & Financial Off. | M | Stock Option (Right to Buy) | 25000 | $0.00 | 162,000.0000 | 57,262,803 | 13.37% | 0.04% |
| Aug. 1, 2024 | Paradigm Biocapital Advisors LP | TenPercentOwner | S | Common Stock, par value $0.0001 per share | 529501 | $14.92 | 5,503,600.0000 | 45,247,098 | 8.78% | 1.17% |
| Aug. 1, 2024 | Paradigm Biocapital Advisors LP | TenPercentOwner | S | Common Stock, par value $0.0001 per share | 1870499 | $14.92 | 5,503,600.0000 | 45,247,098 | 25.37% | 4.13% |
| July 29, 2024 | Harmon Cyrus | Not found | S | Common Stock | 4066 | $15.58 | 874,245.0000 | 45,247,098 | 0.46% | 0.01% |
| July 30, 2024 | Harmon Cyrus | Not found | S | Common Stock | 934 | $15.55 | 873,311.0000 | 45,247,098 | 0.11% | 0.00% |
| July 11, 2024 | Harmon Cyrus | Not found | S | Common Stock | 5000 | $12.26 | 878,311.0000 | 45,247,098 | 0.57% | 0.01% |
| June 28, 2024 | Harmon Cyrus | Not found | S | Common Stock | 20000 | $10.77 | 883,311.0000 | 45,247,098 | 2.21% | 0.04% |
| June 14, 2024 | Graham G. Walmsley | Not found | A | Stock Option (right to buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 14, 2024 | BVF PARTNERS L P/IL | Director | A | Stock Option (Right to buy) | 23000 | $0.00 | 152,120.0000 | 45,247,098 | 17.81% | 0.05% |
| June 14, 2024 | Horning Sandra | Not found | A | Stock Option (right to buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 14, 2024 | RAPPAPORT ANDREW | Not found | A | Stock Option (right to buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 14, 2024 | Harmon Cyrus | Not found | A | Stock Option (Right to Buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 14, 2024 | Larson Yi | Not found | A | Stock Option (Right to Buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 14, 2024 | Hrustanovic Gorjan | Not found | A | Stock Option (right to buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 14, 2024 | CLARK IAN T | Not found | A | Stock Option (right to buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 14, 2024 | Garland J. Scott | Not found | A | Stock Option (Right to Buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 14, 2024 | BUTITTA CYNTHIA M | Not found | A | Stock Option (right to buy) | 23000 | $0.00 | 23,000.0000 | 45,247,098 | 9999.99% | 0.05% |
| June 4, 2024 | Graham G. Walmsley | Director | S | Common Stock | 475000 | $14.85 | 708,114.0000 | 45,247,098 | 40.15% | 1.05% |
| June 4, 2024 | Graham G. Walmsley | Director | S | Common Stock | 700000 | $14.85 | 700,761.0000 | 45,247,098 | 49.97% | 1.55% |
| June 4, 2024 | Harmon Cyrus | Not found | S | Common Stock | 5000 | $12.33 | 903,311.0000 | 45,247,098 | 0.55% | 0.01% |
| May 31, 2024 | Harmon Cyrus | Not found | S | Common Stock | 15000 | $9.41 | 913,311.0000 | 45,247,098 | 1.62% | 0.03% |
| June 3, 2024 | Harmon Cyrus | Not found | S | Common Stock | 5000 | $10.93 | 908,311.0000 | 45,247,098 | 0.55% | 0.01% |
| May 24, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Stock Option (Right to Buy) | 9460 | $0.00 | 126,840.0000 | 45,247,098 | 6.94% | 0.02% |
| May 24, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Common Stock | 9460 | $4.87 | 89,824.0000 | 45,247,098 | 11.77% | 0.02% |
| May 6, 2024 | Harmon Cyrus | Not found | S | Common Stock | 5000 | $10.92 | 928,311.0000 | 45,247,098 | 0.54% | 0.01% |
| April 30, 2024 | Harmon Cyrus | Not found | S | Common Stock | 15000 | $9.51 | 933,311.0000 | 45,247,098 | 1.58% | 0.03% |
| March 28, 2024 | Harmon Cyrus | Not found | S | Common Stock | 20000 | $10.97 | 948,311.0000 | 45,247,098 | 2.07% | 0.04% |
| March 18, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Common Stock | 13700 | $4.87 | 80,364.0000 | 45,247,098 | 20.55% | 0.03% |
| March 18, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Stock Option (Right to Buy) | 13700 | $0.00 | 136,300.0000 | 45,247,098 | 9.13% | 0.03% |
| March 5, 2024 | RAPPAPORT ANDREW | Not found | J | Common Stock | 481014 | $0.00 | 0.0000 | 45,247,098 | 100.00% | 1.06% |
| March 5, 2024 | RAPPAPORT ANDREW | Not found | J | Common Stock | 385965 | $0.00 | 385,965.0000 | 45,247,098 | 9999.99% | 0.85% |
| Feb. 29, 2024 | Harmon Cyrus | Not found | S | Common Stock | 24900 | $12.41 | 968,411.0000 | 45,247,098 | 2.51% | 0.06% |
| Feb. 29, 2024 | Harmon Cyrus | Not found | S | Common Stock | 100 | $13.00 | 968,311.0000 | 45,247,098 | 0.01% | 0.00% |
| Feb. 1, 2024 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | A | Stock Option (Right to Buy) | 304500 | $0.00 | 304,500.0000 | 45,247,098 | 9999.99% | 0.67% |
| Feb. 1, 2024 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | A | Stock Option (Right to Buy) | 195000 | $0.00 | 195,000.0000 | 45,247,098 | 9999.99% | 0.43% |
| Feb. 1, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | A | Stock Option (Right to Buy) | 195000 | $0.00 | 195,000.0000 | 45,247,098 | 9999.99% | 0.43% |
| Feb. 1, 2024 | Bohen Sean | PRESIDENT AND CEO | A | Stock Option (Right to Buy) | 621500 | $0.00 | 621,500.0000 | 45,247,098 | 9999.99% | 1.37% |
| Jan. 31, 2024 | Harmon Cyrus | Not found | S | Common Stock | 25000 | $12.23 | 998,311.0000 | 45,247,098 | 2.44% | 0.06% |
| Feb. 1, 2024 | Harmon Cyrus | Not found | S | Common Stock | 5000 | $15.56 | 993,311.0000 | 45,247,098 | 0.50% | 0.01% |
| Jan. 25, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Common Stock | 20000 | $7.02 | 66,664.0000 | 45,247,098 | 42.86% | 0.04% |
| Jan. 25, 2024 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Stock Option (Right to Buy) | 20000 | $0.00 | 214,000.0000 | 45,247,098 | 8.55% | 0.04% |
| Jan. 12, 2024 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | M | Common Stock | 50000 | $7.02 | 484,987.0000 | 45,247,098 | 11.49% | 0.11% |
| Jan. 12, 2024 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | M | Stock Option (Right to Buy) | 50000 | $0.00 | 187,000.0000 | 45,247,098 | 21.10% | 0.11% |
| Dec. 29, 2023 | Harmon Cyrus | Not found | S | Common Stock | 2500 | $14.10 | 1,023,311.0000 | 0 | 0.24% | 0.00% |
| Dec. 29, 2023 | Harmon Cyrus | Not found | S | Common Stock | 22500 | $13.30 | 1,025,811.0000 | 0 | 2.15% | 0.00% |
| Dec. 5, 2023 | Graham G. Walmsley | Director | P | Common Stock | 50000 | $13.09 | 4,383,875.0000 | 0 | 1.15% | 0.00% |
| Dec. 5, 2023 | Graham G. Walmsley | Director | P | Common Stock | 50000 | $14.95 | 4,333,875.0000 | 0 | 1.17% | 0.00% |
| Sept. 12, 2023 | Graham G. Walmsley | Director | P | Common Stock | 508130 | $9.84 | 4,252,005.0000 | 0 | 13.57% | 0.00% |
| Dec. 5, 2023 | Graham G. Walmsley | Director | P | Common Stock | 31870 | $14.73 | 4,283,875.0000 | 0 | 0.75% | 0.00% |
| Dec. 12, 2023 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | M | Common Stock | 10000 | $7.02 | 434,987.0000 | 0 | 2.35% | 0.00% |
| Dec. 11, 2023 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Stock Option (Right to Buy) | 2900 | $0.00 | 234,000.0000 | 0 | 1.22% | 0.00% |
| Dec. 11, 2023 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Common Stock | 2900 | $7.02 | 46,664.0000 | 0 | 6.63% | 0.00% |
| Dec. 12, 2023 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | M | Stock Option (Right to Buy) | 10000 | $0.00 | 237,000.0000 | 0 | 4.05% | 0.00% |
| Dec. 6, 2023 | Paradigm Biocapital Advisors LP | TenPercentOwner | P | Common Stock, par value $0.0001 per share | 100000 | $11.60 | 7,903,600.0000 | 0 | 1.28% | 0.00% |
| Dec. 6, 2023 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Stock Option (Right to Buy) | 13100 | $0.00 | 236,900.0000 | 0 | 5.24% | 0.00% |
| Dec. 6, 2023 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | M | Common Stock | 13100 | $7.02 | 43,764.0000 | 0 | 42.72% | 0.00% |
| Nov. 30, 2023 | Harmon Cyrus | Not found | S | Common Stock | 25000 | $12.57 | 1,048,311.0000 | 0 | 2.33% | 0.00% |
| Nov. 20, 2023 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | A | Common Stock | 28000 | $0.00 | 45,220.0000 | 0 | 162.60% | 0.00% |
| Nov. 21, 2023 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | S | Common Stock | 7261 | $14.83 | 37,959.0000 | 0 | 16.06% | 0.00% |
| Nov. 21, 2023 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | S | Common Stock | 200 | $15.33 | 37,759.0000 | 0 | 0.53% | 0.00% |
| Nov. 22, 2023 | Zojwalla Naseem | CHIEF MEDICAL OFFICER | S | Common Stock | 7095 | $13.89 | 30,664.0000 | 0 | 18.79% | 0.00% |
| Nov. 20, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | A | Common Stock | 26250 | $0.00 | 755,405.0000 | 0 | 3.60% | 0.00% |
| Nov. 21, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 6776 | $14.87 | 748,629.0000 | 0 | 0.90% | 0.00% |
| Nov. 21, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 200 | $15.32 | 748,429.0000 | 0 | 0.03% | 0.00% |
| Nov. 22, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 6653 | $13.89 | 741,776.0000 | 0 | 0.89% | 0.00% |
| Nov. 21, 2023 | Bohen Sean | PRESIDENT AND CEO | S | Common Stock | 26691 | $14.84 | 175,459.0000 | 0 | 13.20% | 0.00% |
| Nov. 21, 2023 | Bohen Sean | PRESIDENT AND CEO | S | Common Stock | 2602 | $15.29 | 172,857.0000 | 0 | 1.48% | 0.00% |
| Nov. 22, 2023 | Bohen Sean | PRESIDENT AND CEO | S | Common Stock | 27932 | $13.90 | 144,925.0000 | 0 | 16.16% | 0.00% |
| Nov. 20, 2023 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | A | Common Stock | 36750 | $0.00 | 443,729.0000 | 0 | 9.03% | 0.00% |
| Nov. 21, 2023 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | S | Common Stock | 8897 | $14.83 | 434,832.0000 | 0 | 2.01% | 0.00% |
| Nov. 21, 2023 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | S | Common Stock | 700 | $15.27 | 434,132.0000 | 0 | 0.16% | 0.00% |
| Nov. 22, 2023 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | S | Common Stock | 9145 | $13.89 | 424,987.0000 | 0 | 2.11% | 0.00% |
| Nov. 20, 2023 | Bohen Sean | PRESIDENT AND CEO | A | Common Stock | 110250 | $0.00 | 202,150.0000 | 0 | 119.97% | 0.00% |
| Nov. 20, 2023 | Harmon Cyrus | Not found | A | Common Stock | 15750 | $0.00 | 1,081,492.0000 | 0 | 1.48% | 0.00% |
| Nov. 21, 2023 | Harmon Cyrus | Not found | S | Common Stock | 4192 | $14.86 | 1,077,300.0000 | 0 | 0.39% | 0.00% |
| Nov. 22, 2023 | Harmon Cyrus | Not found | S | Common Stock | 3989 | $13.90 | 1,073,311.0000 | 0 | 0.37% | 0.00% |
| Nov. 8, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 200 | $17.61 | 728,947.0000 | 0 | 0.03% | 0.00% |
| Nov. 1, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 6668 | $15.02 | 733,020.0000 | 0 | 0.90% | 0.00% |
| Nov. 2, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 3332 | $15.36 | 729,688.0000 | 0 | 0.45% | 0.00% |
| Nov. 3, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 541 | $17.51 | 729,147.0000 | 0 | 0.07% | 0.00% |
| Oct. 31, 2023 | Harmon Cyrus | Not found | S | Common Stock | 25000 | $12.05 | 1,070,742.0000 | 0 | 2.28% | 0.00% |
| Nov. 2, 2023 | Harmon Cyrus | Not found | S | Common Stock | 5000 | $15.64 | 1,065,742.0000 | 0 | 0.47% | 0.00% |
| Oct. 16, 2023 | Garland J. Scott | Not found | A | Stock Option (Right to Buy) | 21520 | $0.00 | 21,520.0000 | 0 | 9999.99% | 0.00% |
| Oct. 16, 2023 | Garland J. Scott | Not found | A | Stock Option (Right to Buy) | 14347 | $0.00 | 14,347.0000 | 0 | 9999.99% | 0.00% |
| Sept. 29, 2023 | Harmon Cyrus | Not found | S | Common Stock | 25000 | $12.41 | 1,095,742.0000 | 0 | 2.23% | 0.00% |
| Sept. 19, 2023 | Myles David C. | CH. DISCOV. & NON-CLIN DEV OFF | S | Common Stock | 20000 | $12.67 | 739,688.0000 | 0 | 2.63% | 0.00% |
| Sept. 12, 2023 | BVF PARTNERS L P/IL | Director | P | Common stock, $0.0001 par value | 775278 | $9.84 | 4,788,510.0000 | 0 | 19.32% | 0.00% |
| Sept. 12, 2023 | BVF PARTNERS L P/IL | Director | P | Common stock, $0.0001 par value | 677853 | $9.84 | 3,684,068.0000 | 0 | 22.55% | 0.00% |
| Sept. 12, 2023 | BVF PARTNERS L P/IL | Director | P | Common stock, $0.0001 par value | 52801 | $9.84 | 623,707.0000 | 0 | 9.25% | 0.00% |
| Sept. 14, 2023 | BVF PARTNERS L P/IL | Director | J | Common stock, $0.0001 par value | 99556 | $0.00 | 623,707.0000 | 0 | 18.99% | 0.00% |
| Aug. 31, 2023 | Harmon Cyrus | Not found | S | Common Stock | 15000 | $9.36 | 1,130,742.0000 | 0 | 1.31% | 0.00% |
| Sept. 5, 2023 | Harmon Cyrus | Not found | S | Common Stock | 10000 | $11.62 | 1,120,742.0000 | 0 | 0.88% | 0.00% |
| Aug. 16, 2023 | Harmon Cyrus | Not found | S | Common Stock | 15000 | $10.14 | 1,023,714.0000 | 0 | 1.44% | 0.00% |
| Aug. 16, 2023 | Harmon Cyrus | Not found | S | Common Stock | 15000 | $10.14 | 1,145,742.0000 | 0 | 1.29% | 0.00% |
| June 16, 2023 | Larson Yi | Not found | A | Stock Option (right to buy) | 21520 | $0.00 | 21,520.0000 | 0 | 9999.99% | 0.00% |
| June 16, 2023 | Horning Sandra | Not found | A | Stock Option (right to buy) | 21520 | $0.00 | 21,520.0000 | 0 | 9999.99% | 0.00% |
| June 16, 2023 | Hrustanovic Gorjan | Not found | A | Stock Option (right to buy) | 21520 | $0.00 | 21,520.0000 | 0 | 9999.99% | 0.00% |
| June 16, 2023 | Graham G. Walmsley | Not found | A | Stock Option (right to buy) | 21520 | $0.00 | 21,520.0000 | 0 | 9999.99% | 0.00% |
| June 16, 2023 | BUTITTA CYNTHIA M | Not found | A | Stock Option (right to buy) | 21520 | $0.00 | 21,520.0000 | 0 | 9999.99% | 0.00% |
| June 16, 2023 | RAPPAPORT ANDREW | Not found | A | Stock Option (right to buy) | 21520 | $0.00 | 21,520.0000 | 0 | 9999.99% | 0.00% |
| June 16, 2023 | CLARK IAN T | Not found | A | Stock Option (right to buy) | 21520 | $0.00 | 21,520.0000 | 0 | 9999.99% | 0.00% |
| June 16, 2023 | BVF PARTNERS L P/IL | Director | A | Stock Option (Right to buy) | 21520 | $0.00 | 129,120.0000 | 0 | 20.00% | 0.00% |
| June 8, 2023 | Harmon Cyrus | Not found | S | Common Stock | 10000 | $6.30 | 1,160,742.0000 | 0 | 0.85% | 0.00% |
| June 6, 2023 | Harmon Cyrus | Not found | S | Common Stock | 5000 | $6.30 | 1,170,742.0000 | 0 | 0.43% | 0.00% |
| June 5, 2023 | Harmon Cyrus | Not found | S | Common Stock | 5000 | $6.05 | 1,175,742.0000 | 0 | 0.42% | 0.00% |
| April 6, 2023 | Kovacs Shane William Charles | CH. OPERATING & FINANCIAL OFF. | P | Common Stock | 10000 | $0.00 | 396,197.0000 | 0 | 2.59% | 0.00% |
| Feb. 1, 2023 | Myles David C. | Chief Development Officer | A | Stock Option (Right to Buy) | 150000 | $0.00 | 150,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 1, 2023 | Kovacs Shane William Charles | Ch. Operating & Financial Off. | A | Stock Option (Right to Buy) | 200000 | $0.00 | 200,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 1, 2023 | Harmon Cyrus | Chief Research Officer | A | Stock Option (Right to Buy) | 150000 | $0.00 | 150,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 1, 2023 | Horn Kinney | Chief Business Officer | A | Stock Option (Right to Buy) | 150000 | $0.00 | 150,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 1, 2023 | Bohen Sean | President and CEO | A | Stock Option (Right to Buy) | 550000 | $0.00 | 550,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 1, 2023 | Moriarty John B | EVP, Ch. Legal Officer & Sec. | A | Stock Option (Right to Buy) | 150000 | $0.00 | 150,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 1, 2023 | Zojwalla Naseem | Chief Medical Officer | A | Stock Option (Right to Buy) | 150000 | $0.00 | 150,000.0000 | 0 | 9999.99% | 0.00% |