Kymera Therapeutics, Inc. ($KYMR) Insider Transactions

Last updated: 2026-04-02 13:07 UTC | Total transactions: 413

In the last 12 months, insiders at Kymera Therapeutics, Inc. ($KYMR) filed 413 transactions with the SEC: 27 open-market purchases totaling $221,850,155 and 196 sales totaling $149,202,117. Net insider sentiment: net buying.

Kymera Therapeutics, Inc. operates in the Biological products, (no disgnostic substances) industry (Life sciences sector).

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Recent Insider Transactions

Transaction Date Insider Name Title Transaction Type Security Shares Price Shares Owned Following Total Shares Outstanding % of Owned % of Outstanding
April 1, 2026 Chadwick Jeremy G Chief Operating Officer M Stock Option (Right to Buy) 14640 $0.00 68,633.0000 87,300,286 17.58% 0.02%
March 31, 2026 Ridloff Elena Not found M Common Stock 7400 $14.18 7,400.0000 87,300,286 9999.99% 0.01%
March 31, 2026 Ridloff Elena Not found S Common Stock 7400 $85.37 0.0000 87,300,286 100.00% 0.01%
April 1, 2026 Ridloff Elena Not found M Common Stock 4600 $14.18 4,600.0000 87,300,286 9999.99% 0.01%
April 1, 2026 Ridloff Elena Not found S Common Stock 3400 $85.19 1,200.0000 87,300,286 73.91% 0.00%
April 1, 2026 Ridloff Elena Not found S Common Stock 1200 $86.05 0.0000 87,300,286 100.00% 0.00%
March 31, 2026 Ridloff Elena Not found M Stock Option (Right to Buy) 7400 $0.00 4,600.0000 87,300,286 61.67% 0.01%
April 1, 2026 Ridloff Elena Not found M Stock Option (Right to Buy) 4600 $0.00 0.0000 87,300,286 100.00% 0.01%
March 31, 2026 Chadwick Jeremy G Chief Operating Officer M Common Stock 7600 $29.64 68,802.0000 87,300,286 12.42% 0.01%
March 31, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 7600 $85.38 61,202.0000 87,300,286 11.05% 0.01%
April 1, 2026 Chadwick Jeremy G Chief Operating Officer M Common Stock 14640 $29.64 75,842.0000 87,300,286 23.92% 0.02%
April 1, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 13540 $85.41 62,302.0000 87,300,286 17.85% 0.02%
April 1, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 1100 $86.05 61,202.0000 87,300,286 1.77% 0.00%
March 31, 2026 Chadwick Jeremy G Chief Operating Officer M Stock Option (Right to Buy) 7600 $0.00 83,273.0000 87,300,286 8.36% 0.01%
March 23, 2026 Chadwick Jeremy G Chief Operating Officer M Stock Option (Right to Buy) 84400 $0.00 115,600.0000 87,300,286 42.20% 0.10%
March 25, 2026 Chadwick Jeremy G Chief Operating Officer M Stock Option (Right to Buy) 24727 $0.00 90,873.0000 87,300,286 21.39% 0.03%
March 23, 2026 Chadwick Jeremy G Chief Operating Officer M Common Stock 84400 $29.64 152,452.0000 87,300,286 124.02% 0.10%
March 23, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 22756 $76.73 129,696.0000 87,300,286 14.93% 0.03%
March 23, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 52975 $77.21 76,721.0000 87,300,286 40.85% 0.06%
March 23, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 8214 $78.40 68,507.0000 87,300,286 10.71% 0.01%
March 23, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 6105 $79.87 62,402.0000 87,300,286 8.91% 0.01%
March 23, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 1200 $80.05 61,202.0000 87,300,286 1.92% 0.00%
March 25, 2026 Chadwick Jeremy G Chief Operating Officer M Common Stock 24727 $29.64 85,929.0000 87,300,286 40.40% 0.03%
March 25, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 24727 $80.26 61,202.0000 87,300,286 28.78% 0.03%
March 20, 2026 Esposito Pamela Not found S Common Stock 700 $77.71 1,800.0000 87,300,286 28.00% 0.00%
March 20, 2026 Esposito Pamela Not found M Common Stock 2500 $49.10 2,500.0000 87,300,286 9999.99% 0.00%
March 20, 2026 Esposito Pamela Not found M Stock Option (Right to Buy) 2500 $0.00 0.0000 87,300,286 100.00% 0.00%
March 20, 2026 Esposito Pamela Not found S Common Stock 1200 $79.94 0.0000 87,300,286 100.00% 0.00%
March 20, 2026 Esposito Pamela Not found S Common Stock 600 $79.24 1,200.0000 87,300,286 33.33% 0.00%
March 11, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 11111 $83.72 68,052.0000 87,300,286 14.04% 0.01%
March 11, 2026 Chadwick Jeremy G Chief Operating Officer M Stock Option (Right to Buy) 20000 $0.00 60,548.0000 87,300,286 24.83% 0.02%
March 11, 2026 Chadwick Jeremy G Chief Operating Officer M Common Stock 20000 $43.50 93,810.0000 87,300,286 27.10% 0.02%
March 11, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 1765 $82.13 92,045.0000 87,300,286 1.88% 0.00%
March 11, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 12882 $83.10 79,163.0000 87,300,286 14.00% 0.01%
March 2, 2026 Chadwick Jeremy G Chief Operating Officer A Common Stock 12575 $0.00 79,768.0000 87,300,286 18.71% 0.01%
March 2, 2026 Booth Bruce Not found S Common Stock 71814 $90.13 3,902,667.0000 87,300,286 1.81% 0.08%
March 2, 2026 Booth Bruce Not found S Common Stock 10052 $90.13 675,341.0000 87,300,286 1.47% 0.01%
March 2, 2026 Adams Brian Chief Legal Officer A Common Stock 4125 $0.00 56,625.0000 87,300,286 7.86% 0.00%
March 2, 2026 Mainolfi Nello Chief Executive Officer A Stock Option (Right to Buy) 215000 $0.00 215,000.0000 87,300,286 9999.99% 0.25%
March 2, 2026 Jacobs Bruce N. Chief Financial Officer A Stock Option (Right to Buy) 35300 $0.00 35,300.0000 87,300,286 9999.99% 0.04%
March 4, 2026 Jacobs Bruce N. Chief Financial Officer S Common Stock 447 $86.62 232,588.0000 87,300,286 0.19% 0.00%
March 4, 2026 Jacobs Bruce N. Chief Financial Officer S Common Stock 1437 $85.78 233,035.0000 87,300,286 0.61% 0.00%
March 4, 2026 Jacobs Bruce N. Chief Financial Officer S Common Stock 2519 $85.04 234,472.0000 87,300,286 1.06% 0.00%
March 4, 2026 Jacobs Bruce N. Chief Financial Officer S Common Stock 492 $84.00 236,991.0000 87,300,286 0.21% 0.00%
March 2, 2026 Jacobs Bruce N. Chief Financial Officer S Common Stock 4113 $89.66 237,483.0000 87,300,286 1.70% 0.00%
March 2, 2026 Jacobs Bruce N. Chief Financial Officer S Common Stock 1424 $88.50 241,596.0000 87,300,286 0.59% 0.00%
March 2, 2026 Jacobs Bruce N. Chief Financial Officer S Common Stock 2039 $87.75 243,020.0000 87,300,286 0.83% 0.00%
March 2, 2026 Jacobs Bruce N. Chief Financial Officer A Common Stock 17650 $0.00 245,059.0000 87,300,286 7.76% 0.02%
March 2, 2026 Gollob Jared Chief Medical Officer A Stock Option (Right to Buy) 35300 $0.00 35,300.0000 87,300,286 9999.99% 0.04%
March 4, 2026 Gollob Jared Chief Medical Officer S Common Stock 447 $86.62 117,134.0000 87,300,286 0.38% 0.00%
March 4, 2026 Gollob Jared Chief Medical Officer S Common Stock 1437 $85.78 117,581.0000 87,300,286 1.21% 0.00%
March 4, 2026 Gollob Jared Chief Medical Officer S Common Stock 2519 $85.04 119,018.0000 87,300,286 2.07% 0.00%
March 4, 2026 Gollob Jared Chief Medical Officer S Common Stock 492 $84.00 121,537.0000 87,300,286 0.40% 0.00%
March 2, 2026 Gollob Jared Chief Medical Officer S Common Stock 3048 $89.66 122,029.0000 87,300,286 2.44% 0.00%
March 2, 2026 Gollob Jared Chief Medical Officer S Common Stock 1055 $88.50 125,077.0000 87,300,286 0.84% 0.00%
March 2, 2026 Gollob Jared Chief Medical Officer S Common Stock 1510 $87.75 126,132.0000 87,300,286 1.18% 0.00%
March 2, 2026 Gollob Jared Chief Medical Officer A Common Stock 17650 $0.00 127,642.0000 87,300,286 16.05% 0.02%
March 2, 2026 Goodman Noah Chief Business Officer A Stock Option (Right to Buy) 18450 $0.00 18,450.0000 87,300,286 9999.99% 0.02%
March 2, 2026 Goodman Noah Chief Business Officer A Common Stock 9225 $0.00 59,306.4380 87,300,286 18.42% 0.01%
March 2, 2026 Chadwick Jeremy G Chief Operating Officer A Stock Option (Right to Buy) 25150 $0.00 25,150.0000 87,300,286 9999.99% 0.03%
March 4, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 358 $86.62 73,810.0000 87,300,286 0.48% 0.00%
March 4, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 1150 $85.78 74,168.0000 87,300,286 1.53% 0.00%
March 4, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 2017 $85.04 75,318.0000 87,300,286 2.61% 0.00%
March 4, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 394 $84.00 77,335.0000 87,300,286 0.51% 0.00%
March 2, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 1107 $89.66 77,729.0000 87,300,286 1.40% 0.00%
March 2, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 383 $88.50 78,836.0000 87,300,286 0.48% 0.00%
March 2, 2026 Chadwick Jeremy G Chief Operating Officer S Common Stock 549 $87.75 79,219.0000 87,300,286 0.69% 0.00%
March 2, 2026 Adams Brian Chief Legal Officer A Stock Option (Right to Buy) 8250 $0.00 8,250.0000 87,300,286 9999.99% 0.01%
Feb. 25, 2026 Mainolfi Nello Chief Executive Officer S Common Stock 8 $93.49 666,195.0000 87,300,286 0.00% 0.00%
Feb. 25, 2026 Mainolfi Nello Chief Executive Officer S Common Stock 1501 $92.81 666,203.0000 87,300,286 0.22% 0.00%
Feb. 25, 2026 Mainolfi Nello Chief Executive Officer M Common Stock 30000 $2.08 696,195.0000 87,300,286 4.50% 0.03%
Feb. 25, 2026 Mainolfi Nello Chief Executive Officer S Common Stock 19764 $89.78 676,431.0000 87,300,286 2.84% 0.02%
Feb. 25, 2026 Mainolfi Nello Chief Executive Officer S Common Stock 3293 $91.76 667,704.0000 87,300,286 0.49% 0.00%
Feb. 25, 2026 Mainolfi Nello Chief Executive Officer S Common Stock 5434 $90.39 670,997.0000 87,300,286 0.80% 0.01%
Feb. 25, 2026 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 30000 $0.00 245,559.0000 87,300,286 10.89% 0.03%
Feb. 20, 2026 Esposito Pamela Not found S Common Stock 1900 $87.06 600.0000 87,300,286 76.00% 0.00%
Feb. 20, 2026 Esposito Pamela Not found M Stock Option (Right to Buy) 2500 $0.00 2,500.0000 87,300,286 50.00% 0.00%
Feb. 20, 2026 Esposito Pamela Not found M Common Stock 2500 $49.10 2,500.0000 87,300,286 9999.99% 0.00%
Feb. 20, 2026 Esposito Pamela Not found S Common Stock 600 $88.10 0.0000 87,300,286 100.00% 0.00%
Jan. 20, 2026 Esposito Pamela Not found M Common Stock 3000 $31.20 3,000.0000 87,300,286 9999.99% 0.00%
Jan. 20, 2026 Esposito Pamela Not found S Common Stock 200 $68.52 0.0000 87,300,286 100.00% 0.00%
Jan. 20, 2026 Esposito Pamela Not found M Stock Option (Right to Buy) 3000 $0.00 10,000.0000 87,300,286 23.08% 0.00%
Jan. 20, 2026 Esposito Pamela Not found M Stock Option (Right to Buy) 2500 $0.00 5,000.0000 87,300,286 33.33% 0.00%
Jan. 20, 2026 Esposito Pamela Not found M Common Stock 2500 $49.10 5,500.0000 87,300,286 83.33% 0.00%
Jan. 20, 2026 Esposito Pamela Not found S Common Stock 400 $66.68 5,100.0000 87,300,286 7.27% 0.00%
Jan. 20, 2026 Esposito Pamela Not found S Common Stock 4900 $67.99 200.0000 87,300,286 96.08% 0.01%
Jan. 5, 2026 Mainolfi Nello Chief Executive Officer M Common Stock 3118 $32.07 666,195.0000 87,300,286 0.47% 0.00%
Jan. 5, 2026 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 3118 $0.00 446,882.0000 87,300,286 0.69% 0.00%
Dec. 31, 2025 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 30000 $0.00 275,559.0000 87,300,286 9.82% 0.03%
Dec. 31, 2025 Mainolfi Nello Chief Executive Officer M Common Stock 30000 $2.08 693,077.0000 87,300,286 4.52% 0.03%
Dec. 31, 2025 Mainolfi Nello Chief Executive Officer S Common Stock 23986 $77.95 669,091.0000 87,300,286 3.46% 0.03%
Dec. 31, 2025 Mainolfi Nello Chief Executive Officer S Common Stock 6014 $78.52 663,077.0000 87,300,286 0.90% 0.01%
Dec. 17, 2025 Esposito Pamela Not found S Common Stock 7959 $82.34 5,099.0000 87,300,286 60.95% 0.01%
Dec. 17, 2025 Esposito Pamela Not found M Common Stock 3000 $31.20 27,563.0000 87,300,286 12.21% 0.00%
Dec. 17, 2025 Esposito Pamela Not found M Common Stock 12000 $27.67 24,563.0000 87,300,286 95.52% 0.01%
Dec. 17, 2025 Esposito Pamela Not found M Common Stock 12563 $49.10 12,563.0000 87,300,286 9999.99% 0.01%
Dec. 17, 2025 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 2595 $0.00 272,505.0000 87,300,286 0.94% 0.00%
Dec. 17, 2025 Mainolfi Nello Chief Executive Officer M Common Stock 2595 $38.53 663,077.0000 87,300,286 0.39% 0.00%
Dec. 17, 2025 Esposito Pamela Not found M Stock Option (Right to Buy) 3000 $0.00 13,000.0000 87,300,286 18.75% 0.00%
Dec. 17, 2025 Esposito Pamela Not found M Stock Option (Right to Buy) 12000 $0.00 0.0000 87,300,286 100.00% 0.01%
Dec. 17, 2025 Esposito Pamela Not found M Stock Option (Right to Buy) 12563 $0.00 7,500.0000 87,300,286 62.62% 0.01%
Dec. 17, 2025 Esposito Pamela Not found S Common Stock 1000 $84.07 0.0000 87,300,286 100.00% 0.00%
Dec. 17, 2025 Esposito Pamela Not found S Common Stock 4099 $83.45 1,000.0000 87,300,286 80.39% 0.00%
Dec. 17, 2025 Esposito Pamela Not found S Common Stock 14505 $81.56 13,058.0000 87,300,286 52.62% 0.02%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 5979 $88.64 717,267.0000 87,300,286 0.83% 0.01%
Dec. 12, 2025 Booth Bruce Not found S Common Stock 108 $91.04 685,393.0000 87,300,286 0.02% 0.00%
Dec. 12, 2025 Booth Bruce Not found S Common Stock 570 $91.04 3,974,481.0000 87,300,286 0.01% 0.00%
Dec. 11, 2025 Booth Bruce Not found S Common Stock 976 $91.23 685,501.0000 87,300,286 0.14% 0.00%
Dec. 11, 2025 Booth Bruce Not found S Common Stock 5125 $91.23 3,975,051.0000 87,300,286 0.13% 0.01%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 16338 $93.20 686,477.0000 87,300,286 2.32% 0.02%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 9060 $92.41 702,815.0000 87,300,286 1.27% 0.01%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 2001 $90.14 711,875.0000 87,300,286 0.28% 0.00%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 3391 $89.25 713,876.0000 87,300,286 0.47% 0.00%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 85862 $93.20 3,980,176.0000 87,300,286 2.11% 0.10%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 47349 $92.41 4,066,038.0000 87,300,286 1.15% 0.05%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 10545 $90.14 4,113,387.0000 87,300,286 0.26% 0.01%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 17825 $89.25 4,123,932.0000 87,300,286 0.43% 0.02%
Dec. 10, 2025 Booth Bruce Not found S Common Stock 31459 $88.64 4,141,757.0000 87,300,286 0.75% 0.04%
Dec. 11, 2025 BAKER BROS. ADVISORS LP Not found P Common Stock 167192 $86.00 701,326.0000 87,300,286 31.30% 0.19%
Dec. 11, 2025 BAKER BROS. ADVISORS LP Not found P Common Stock 1838621 $86.00 7,955,916.0000 87,300,286 30.06% 2.11%
Dec. 8, 2025 Albers Jeffrey W. Not found S Common Stock 2252 $90.30 0.0000 87,300,286 100.00% 0.00%
Dec. 8, 2025 Albers Jeffrey W. Not found M Common Stock 5000 $14.18 5,000.0000 87,300,286 9999.99% 0.01%
Dec. 8, 2025 Albers Jeffrey W. Not found S Common Stock 2748 $89.32 2,252.0000 87,300,286 54.96% 0.00%
Dec. 8, 2025 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 100000 $0.00 305,559.0000 87,300,286 24.66% 0.11%
Dec. 8, 2025 Mainolfi Nello Chief Executive Officer S Common Stock 100000 $89.17 660,482.0000 87,300,286 13.15% 0.11%
Dec. 8, 2025 Gollob Jared Chief Medical Officer M Common Stock 49307 $5.33 159,299.0000 87,300,286 44.83% 0.06%
Dec. 8, 2025 Mainolfi Nello Chief Executive Officer M Common Stock 100000 $2.08 760,482.0000 87,300,286 15.14% 0.11%
Dec. 8, 2025 Gollob Jared Chief Medical Officer S Common Stock 18357 $88.02 127,183.0000 87,300,286 12.61% 0.02%
Dec. 8, 2025 Gollob Jared Chief Medical Officer S Common Stock 3929 $89.43 123,254.0000 87,300,286 3.09% 0.00%
Dec. 8, 2025 Gollob Jared Chief Medical Officer S Common Stock 8562 $90.12 114,692.0000 87,300,286 6.95% 0.01%
Dec. 8, 2025 Gollob Jared Chief Medical Officer S Common Stock 3300 $91.46 111,392.0000 87,300,286 2.88% 0.00%
Dec. 8, 2025 Gollob Jared Chief Medical Officer S Common Stock 1400 $92.19 109,992.0000 87,300,286 1.26% 0.00%
Dec. 8, 2025 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 49307 $0.00 34,083.0000 87,300,286 59.13% 0.06%
Dec. 8, 2025 Gollob Jared Chief Medical Officer S Common Stock 13759 $87.37 145,540.0000 87,300,286 8.64% 0.02%
Dec. 8, 2025 Albers Jeffrey W. Not found M Stock Option (Right to Buy) 5000 $0.00 7,000.0000 87,300,286 41.67% 0.01%
Oct. 29, 2025 Mainolfi Nello Chief Executive Officer S Common Stock 1862 $59.72 688,620.0000 87,300,286 0.27% 0.00%
Oct. 29, 2025 Mainolfi Nello Chief Executive Officer M Common Stock 30000 $2.08 690,482.0000 87,300,286 4.54% 0.03%
Oct. 29, 2025 Mainolfi Nello Chief Executive Officer S Common Stock 24511 $61.02 664,109.0000 87,300,286 3.56% 0.03%
Oct. 29, 2025 Mainolfi Nello Chief Executive Officer S Common Stock 3627 $61.46 660,482.0000 87,300,286 0.55% 0.00%
Oct. 29, 2025 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 30000 $0.00 405,559.0000 87,300,286 6.89% 0.03%
Oct. 15, 2025 Gollob Jared Chief Medical Officer S Common Stock 8963 $61.49 131,341.0000 87,300,286 6.39% 0.01%
Oct. 15, 2025 Gollob Jared Chief Medical Officer S Common Stock 29264 $60.37 140,304.0000 87,300,286 17.26% 0.03%
Oct. 15, 2025 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 22210 $0.00 0.0000 87,300,286 100.00% 0.03%
Oct. 15, 2025 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 28999 $0.00 0.0000 87,300,286 100.00% 0.03%
Oct. 15, 2025 Gollob Jared Chief Medical Officer M Common Stock 28999 $1.31 147,358.0000 87,300,286 24.50% 0.03%
Oct. 15, 2025 Gollob Jared Chief Medical Officer S Common Stock 6453 $63.09 109,992.0000 87,300,286 5.54% 0.01%
Oct. 15, 2025 Gollob Jared Chief Medical Officer M Common Stock 22210 $2.08 169,568.0000 87,300,286 15.07% 0.03%
Oct. 15, 2025 Gollob Jared Chief Medical Officer S Common Stock 14896 $62.72 116,445.0000 87,300,286 11.34% 0.02%
Oct. 13, 2025 Gollob Jared Chief Medical Officer M Common Stock 800 $1.31 120,800.0000 87,300,286 0.67% 0.00%
Oct. 13, 2025 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 800 $0.00 28,999.0000 87,300,286 2.68% 0.00%
Oct. 13, 2025 Gollob Jared Chief Medical Officer S Common Stock 3114 $60.00 118,359.0000 87,300,286 2.56% 0.00%
Oct. 13, 2025 Albers Jeffrey W. Not found M Common Stock 5000 $10.34 5,000.0000 87,300,286 9999.99% 0.01%
Oct. 13, 2025 Albers Jeffrey W. Not found S Common Stock 5000 $59.19 0.0000 87,300,286 100.00% 0.01%
Oct. 13, 2025 Albers Jeffrey W. Not found M Stock Option (Right to Buy) 5000 $0.00 0.0000 87,300,286 100.00% 0.01%
Oct. 13, 2025 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 673 $0.00 22,210.0000 87,300,286 2.94% 0.00%
Oct. 13, 2025 Gollob Jared Chief Medical Officer M Common Stock 673 $2.08 121,473.0000 87,300,286 0.56% 0.00%
Sept. 17, 2025 Jacobs Bruce N. Chief Financial Officer M Stock Option (Right to Buy) 42246 $0.00 27,653.0000 75,043,991 60.44% 0.06%
Sept. 17, 2025 Jacobs Bruce N. Chief Financial Officer S Common Stock 79220 $50.00 227,409.0000 75,043,991 25.84% 0.11%
Sept. 17, 2025 Jacobs Bruce N. Chief Financial Officer M Stock Option (Right to Buy) 36974 $0.00 0.0000 75,043,991 100.00% 0.05%
Sept. 17, 2025 Jacobs Bruce N. Chief Financial Officer M Common Stock 79220 $2.08 306,629.0000 75,043,991 34.84% 0.11%
Sept. 16, 2025 Mainolfi Nello Chief Executive Officer S Common Stock 30000 $49.00 660,482.0000 75,043,991 4.34% 0.04%
Sept. 16, 2025 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 30000 $0.00 435,559.0000 75,043,991 6.44% 0.04%
Sept. 16, 2025 Mainolfi Nello Chief Executive Officer M Common Stock 30000 $2.08 690,482.0000 75,043,991 4.54% 0.04%
Sept. 3, 2025 Adams Brian Chief Legal Officer A Stock Option (Right to Buy) 105000 $0.00 105,000.0000 75,043,991 9999.99% 0.14%
Sept. 3, 2025 Adams Brian Chief Legal Officer A Common Stock 52500 $0.00 52,500.0000 75,043,991 9999.99% 0.07%
June 30, 2025 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 142604 $44.00 2,798,795.0000 75,043,991 5.37% 0.19%
June 30, 2025 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 115783 $44.00 2,219,858.0000 75,043,991 5.50% 0.15%
June 30, 2025 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 58780 $44.00 353,412.0000 75,043,991 19.95% 0.08%
June 25, 2025 BVF PARTNERS L P/IL Other A Stock Option (Right to Buy) 16000 $0.00 116,190.0000 75,043,991 15.97% 0.02%
June 30, 2025 BAKER BROS. ADVISORS LP Not found P Common Stock 600309 $44.00 6,117,295.0000 75,043,991 10.88% 0.80%
June 30, 2025 BAKER BROS. ADVISORS LP Not found P Prefunded Warrants 600309 $44.00 10,225,962.0000 75,043,991 6.24% 0.80%
June 30, 2025 BAKER BROS. ADVISORS LP Not found P Prefunded Warrants 55191 $44.00 974,192.0000 75,043,991 6.01% 0.07%
June 30, 2025 BAKER BROS. ADVISORS LP Not found P Common Stock 55191 $44.00 534,134.0000 75,043,991 11.52% 0.07%
June 25, 2025 Albers Jeffrey W. Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 25, 2025 MARAGANORE JOHN Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 25, 2025 Esposito Pamela Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 25, 2025 Hrustanovic Gorjan Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 25, 2025 BAKER BROS. ADVISORS LP Not found A Non-Qualified Stock Option (right to buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 25, 2025 Ridloff Elena Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 25, 2025 Sandor Victor Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 25, 2025 Booth Bruce Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 25, 2025 BAKER BROS. ADVISORS LP Not found A Non-Qualified Stock Option (right to buy) 16000 $0.00 16,000.0000 75,043,991 9999.99% 0.02%
June 11, 2025 Ridloff Elena Not found S Common Stock 4500 $50.00 0.0000 75,043,991 100.00% 0.01%
June 11, 2025 Ridloff Elena Not found M Common Stock 4500 $20.29 4,500.0000 75,043,991 9999.99% 0.01%
June 11, 2025 Ridloff Elena Not found M Stock Option (Right to Buy) 4500 $0.00 4,500.0000 75,043,991 50.00% 0.01%
June 3, 2025 Albers Jeffrey W. Not found M Stock Option (Right to Buy) 6349 $0.00 5,000.0000 75,043,991 55.94% 0.01%
June 3, 2025 Esposito Pamela Not found M Common Stock 5000 $29.55 5,000.0000 75,043,991 9999.99% 0.01%
June 3, 2025 Esposito Pamela Not found S Common Stock 5000 $49.04 0.0000 75,043,991 100.00% 0.01%
June 3, 2025 Esposito Pamela Not found M Stock Option (Right to Buy) 5000 $0.00 24,127.0000 75,043,991 17.17% 0.01%
June 3, 2025 Ridloff Elena Not found M Common Stock 12000 $27.67 12,000.0000 75,043,991 9999.99% 0.02%
June 3, 2025 Ridloff Elena Not found S Common Stock 7200 $45.50 4,800.0000 75,043,991 60.00% 0.01%
June 3, 2025 Ridloff Elena Not found S Common Stock 4800 $47.00 0.0000 75,043,991 100.00% 0.01%
June 3, 2025 Ridloff Elena Not found M Stock Option (Right to Buy) 12000 $0.00 0.0000 75,043,991 100.00% 0.02%
June 3, 2025 Mainolfi Nello Chief Executive Officer M Common Stock 30000 $2.08 690,482.0000 75,043,991 4.54% 0.04%
June 3, 2025 Mainolfi Nello Chief Executive Officer S Common Stock 30000 $49.00 660,482.0000 75,043,991 4.34% 0.04%
June 3, 2025 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 30000 $0.00 465,559.0000 75,043,991 6.05% 0.04%
June 3, 2025 Albers Jeffrey W. Not found M Common Stock 6349 $10.34 6,349.0000 75,043,991 9999.99% 0.01%
June 3, 2025 Albers Jeffrey W. Not found S Common Stock 6349 $49.00 0.0000 75,043,991 100.00% 0.01%
May 23, 2025 Chadwick Jeremy G Chief Operating Officer S Common Stock 2575 $29.30 66,420.0000 75,043,991 3.73% 0.00%
April 8, 2025 Goodman Noah Chief Business Officer A Stock Option (Right to Buy) 100000 $0.00 100,000.0000 75,043,991 9999.99% 0.13%
April 8, 2025 Goodman Noah Chief Business Officer A Common Stock 50000 $0.00 50,081.4380 75,043,991 9999.99% 0.07%
March 31, 2025 Jacobs Bruce N. Chief Financial Officer M Stock Option (Right to Buy) 25000 $0.00 69,899.0000 75,043,991 26.34% 0.03%
March 31, 2025 Jacobs Bruce N. Chief Financial Officer M Common Stock 25000 $2.08 226,886.0000 75,043,991 12.38% 0.03%
March 3, 2025 Gollob Jared Chief Medical Officer A Common Stock 30000 $0.00 125,740.0000 75,043,991 31.33% 0.04%
March 3, 2025 Chiniara Ellen Chief Legal Officer A Common Stock 27500 $0.00 82,326.0000 75,043,991 50.16% 0.04%
March 3, 2025 Chiniara Ellen Chief Legal Officer S Common Stock 1833 $30.33 80,493.0000 75,043,991 2.23% 0.00%
March 3, 2025 Chiniara Ellen Chief Legal Officer S Common Stock 408 $31.00 80,085.0000 75,043,991 0.51% 0.00%
March 3, 2025 Chiniara Ellen Chief Legal Officer A Stock Option (Right to Buy) 55000 $0.00 55,000.0000 75,043,991 9999.99% 0.07%
March 3, 2025 Chadwick Jeremy G Chief Operating Officer A Common Stock 25000 $0.00 69,183.0000 75,043,991 56.58% 0.03%
March 3, 2025 Chadwick Jeremy G Chief Operating Officer S Common Stock 1131 $30.33 68,052.0000 75,043,991 1.63% 0.00%
March 3, 2025 Chadwick Jeremy G Chief Operating Officer S Common Stock 252 $31.00 67,800.0000 75,043,991 0.37% 0.00%
March 3, 2025 Chadwick Jeremy G Chief Operating Officer A Stock Option (Right to Buy) 50000 $0.00 50,000.0000 75,043,991 9999.99% 0.07%
March 3, 2025 Jacobs Bruce N. Chief Financial Officer A Common Stock 30000 $0.00 208,921.0000 75,043,991 16.77% 0.04%
March 3, 2025 Jacobs Bruce N. Chief Financial Officer S Common Stock 5754 $30.33 203,167.0000 75,043,991 2.75% 0.01%
March 3, 2025 Jacobs Bruce N. Chief Financial Officer S Common Stock 1281 $31.00 201,886.0000 75,043,991 0.63% 0.00%
March 3, 2025 Jacobs Bruce N. Chief Financial Officer A Stock Option (Right to Buy) 60000 $0.00 60,000.0000 75,043,991 9999.99% 0.08%
March 3, 2025 Mainolfi Nello Chief Executive Officer A Stock Option (Right to Buy) 365000 $0.00 365,000.0000 75,043,991 9999.99% 0.49%
March 3, 2025 Gollob Jared Chief Medical Officer S Common Stock 4695 $30.33 121,045.0000 75,043,991 3.73% 0.01%
March 3, 2025 Gollob Jared Chief Medical Officer S Common Stock 1045 $31.00 120,000.0000 75,043,991 0.86% 0.00%
March 3, 2025 Gollob Jared Chief Medical Officer A Stock Option (Right to Buy) 60000 $0.00 60,000.0000 75,043,991 9999.99% 0.08%
Jan. 10, 2025 Mainolfi Nello Chief Executive Officer M Common Stock 10000 $2.08 659,959.0000 75,043,991 1.54% 0.01%
Jan. 10, 2025 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 10000 $0.00 495,559.0000 75,043,991 2.06% 0.01%
Jan. 10, 2025 Jacobs Bruce N. Chief Financial Officer M Common Stock 10000 $2.08 178,921.0000 75,043,991 5.92% 0.01%
Jan. 10, 2025 Jacobs Bruce N. Chief Financial Officer M Stock Option (Right to Buy) 10000 $0.00 94,899.0000 75,043,991 9.53% 0.01%
Jan. 6, 2025 Chiniara Ellen Chief Legal Officer S Common Stock 3129 $41.75 54,826.0000 75,043,991 5.40% 0.00%
Dec. 2, 2024 Esposito Pamela Not found S Common Stock 2500 $49.00 0.0000 76,125,975 100.00% 0.00%
Dec. 2, 2024 Esposito Pamela Not found M Common Stock 2500 $29.55 2,500.0000 76,125,975 9999.99% 0.00%
Dec. 2, 2024 Esposito Pamela Not found M Stock Option (Right to Buy) 2500 $0.00 29,127.0000 76,125,975 7.90% 0.00%
Sept. 17, 2024 Esposito Pamela Not found M Stock Option (Right to Buy) 8500 $0.00 31,627.0000 58,365,499 21.18% 0.01%
Sept. 17, 2024 Esposito Pamela Not found M Common Stock 8500 $29.55 8,500.0000 58,365,499 9999.99% 0.01%
Sept. 17, 2024 Esposito Pamela Not found M Common Stock 5000 $14.18 13,500.0000 58,365,499 58.82% 0.01%
Sept. 17, 2024 Esposito Pamela Not found S Common Stock 6350 $47.75 7,150.0000 58,365,499 47.04% 0.01%
Sept. 17, 2024 Esposito Pamela Not found S Common Stock 7150 $48.75 0.0000 58,365,499 100.00% 0.01%
Sept. 17, 2024 Esposito Pamela Not found M Stock Option (Right to Buy) 5000 $0.00 7,000.0000 58,365,499 41.67% 0.01%
Aug. 26, 2024 Albers Jeffrey W. Not found S Common Stock 5000 $49.10 0.0000 58,365,499 100.00% 0.01%
Aug. 26, 2024 Albers Jeffrey W. Not found M Common Stock 5000 $10.34 5,000.0000 58,365,499 9999.99% 0.01%
Aug. 26, 2024 Albers Jeffrey W. Not found M Stock Option (Right to Buy) 5000 $0.00 11,349.0000 58,365,499 30.58% 0.01%
Aug. 21, 2024 BAKER BROS. ADVISORS LP Not found P Prefunded Warrants 347572 $40.75 919,001.0000 58,365,499 60.83% 0.60%
Aug. 20, 2024 BVF PARTNERS L P/IL Other P Pre-Funded Warrants to Purchase Common Stock 201546 $40.75 1,180,560.0000 58,365,499 20.59% 0.35%
Aug. 20, 2024 BVF PARTNERS L P/IL Other P Pre-Funded Warrants to Purchase Common Stock 156742 $40.75 1,135,756.0000 58,365,499 16.01% 0.27%
Aug. 20, 2024 BAKER BROS. ADVISORS LP Not found P Common Stock 1 $46.41 5,995,929.0000 58,365,499 0.00% 0.00%
Aug. 21, 2024 BAKER BROS. ADVISORS LP Not found P Prefunded Warrants 2246587 $40.75 9,625,653.0000 58,365,499 30.45% 3.85%
July 15, 2024 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 16455 $0.00 46,028.0000 58,365,499 26.34% 0.03%
July 15, 2024 Gollob Jared Chief Medical Officer M Common Stock 16455 $2.08 112,195.0000 58,365,499 17.19% 0.03%
July 15, 2024 Gollob Jared Chief Medical Officer S Common Stock 16455 $45.15 95,740.0000 58,365,499 14.67% 0.03%
July 16, 2024 Gollob Jared Chief Medical Officer M Common Stock 23145 $2.08 118,885.0000 58,365,499 24.17% 0.04%
July 16, 2024 Gollob Jared Chief Medical Officer S Common Stock 13281 $45.59 105,604.0000 58,365,499 11.17% 0.02%
July 16, 2024 Gollob Jared Chief Medical Officer S Common Stock 9864 $46.10 95,470.0000 58,365,499 9.36% 0.02%
July 16, 2024 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 23145 $0.00 22,883.0000 58,365,499 50.28% 0.04%
July 9, 2024 Booth Bruce Not found S Common Stock 24449 $35.57 4,523,951.0000 58,365,499 0.54% 0.04%
July 9, 2024 Booth Bruce Not found S Common Stock 28718 $36.40 4,495,233.0000 58,365,499 0.63% 0.05%
July 9, 2024 Booth Bruce Not found S Common Stock 41763 $37.41 4,453,470.0000 58,365,499 0.93% 0.07%
July 9, 2024 Booth Bruce Not found S Common Stock 183868 $38.48 4,269,602.0000 58,365,499 4.13% 0.32%
July 9, 2024 Booth Bruce Not found S Common Stock 96386 $39.26 4,173,216.0000 58,365,499 2.26% 0.17%
July 9, 2024 Booth Bruce Not found S Common Stock 5133 $35.57 796,889.0000 58,365,499 0.64% 0.01%
July 9, 2024 Booth Bruce Not found S Common Stock 6030 $36.40 790,859.0000 58,365,499 0.76% 0.01%
July 9, 2024 Booth Bruce Not found S Common Stock 8769 $37.41 782,090.0000 58,365,499 1.11% 0.02%
July 9, 2024 Booth Bruce Not found S Common Stock 38606 $38.48 743,484.0000 58,365,499 4.94% 0.07%
July 9, 2024 Booth Bruce Not found S Common Stock 20238 $39.26 723,246.0000 58,365,499 2.72% 0.03%
July 1, 2024 Mainolfi Nello Chief Executive Officer M Common Stock 18773 $5.33 649,959.0000 58,365,499 2.97% 0.03%
July 1, 2024 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 18773 $0.00 288,456.0000 58,365,499 6.11% 0.03%
June 27, 2024 Jacobs Bruce N. Chief Financial Officer M Stock Option (Right to Buy) 25000 $0.00 104,899.0000 58,365,499 19.25% 0.04%
June 18, 2024 BVF PARTNERS L P/IL Other A Stock Option (Right to Buy) 16000 $0.00 100,190.0000 58,365,499 19.00% 0.03%
June 27, 2024 Jacobs Bruce N. Chief Financial Officer M Common Stock 25000 $2.08 168,554.0000 58,365,499 17.42% 0.04%
June 18, 2024 Hrustanovic Gorjan Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 58,365,499 9999.99% 0.03%
June 18, 2024 MARAGANORE JOHN Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 58,365,499 9999.99% 0.03%
June 18, 2024 Morgan Leigh Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 58,365,499 9999.99% 0.03%
June 18, 2024 Sandor Victor Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 58,365,499 9999.99% 0.03%
June 18, 2024 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 14413 $0.00 505,559.0000 58,365,499 2.77% 0.02%
June 18, 2024 Mainolfi Nello Chief Executive Officer M Common Stock 14413 $2.08 631,186.0000 58,365,499 2.34% 0.02%
June 18, 2024 Esposito Pamela Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 58,365,499 9999.99% 0.03%
June 18, 2024 Booth Bruce Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 58,365,499 9999.99% 0.03%
June 18, 2024 Albers Jeffrey W. Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 58,365,499 9999.99% 0.03%
June 18, 2024 Ridloff Elena Not found A Stock Option (Right to Buy) 16000 $0.00 16,000.0000 58,365,499 9999.99% 0.03%
June 13, 2024 Booth Bruce Not found S Common Stock 8430 $34.98 4,548,400.0000 58,365,499 0.18% 0.01%
June 12, 2024 Booth Bruce Not found S Common Stock 11838 $35.35 4,558,827.0000 58,365,499 0.26% 0.02%
June 12, 2024 Booth Bruce Not found S Common Stock 1997 $36.02 4,556,830.0000 58,365,499 0.04% 0.00%
June 12, 2024 Booth Bruce Not found S Common Stock 2485 $35.35 804,212.0000 58,365,499 0.31% 0.00%
June 12, 2024 Booth Bruce Not found S Common Stock 420 $36.02 803,792.0000 58,365,499 0.05% 0.00%
June 13, 2024 Booth Bruce Not found S Common Stock 1770 $34.98 802,022.0000 58,365,499 0.22% 0.00%
June 7, 2024 Horobin Joanna Not found M Stock Option (Right to Buy) 8500 $0.00 33,195.0000 58,365,499 20.39% 0.01%
June 7, 2024 Horobin Joanna Not found M Common Stock 8500 $2.08 8,500.0000 58,365,499 9999.99% 0.01%
June 7, 2024 Horobin Joanna Not found S Common Stock 2187 $32.65 6,313.0000 58,365,499 25.73% 0.00%
June 7, 2024 Horobin Joanna Not found S Common Stock 6313 $33.11 0.0000 58,365,499 100.00% 0.01%
May 23, 2024 Chadwick Jeremy G Chief Operating Officer S Common Stock 2575 $34.99 44,183.0000 58,365,499 5.51% 0.00%
March 28, 2024 BAKER BROS. ADVISORS LP Not found A Non-Qualified Stock Option (right to buy) 32000 $0.00 32,000.0000 58,365,499 9999.99% 0.05%
March 28, 2024 BAKER BROS. ADVISORS LP Not found A Non-Qualified Stock Option (right to buy) 32000 $0.00 32,000.0000 58,365,499 9999.99% 0.05%
March 15, 2024 Booth Bruce Not found S Common Stock 1714 $39.31 817,437.0000 58,365,499 0.21% 0.00%
March 14, 2024 Booth Bruce Not found S Common Stock 34473 $39.73 4,641,602.0000 58,365,499 0.74% 0.06%
March 14, 2024 Booth Bruce Not found S Common Stock 10846 $40.66 4,630,756.0000 58,365,499 0.23% 0.02%
March 15, 2024 Booth Bruce Not found S Common Stock 329 $41.23 806,697.0000 58,365,499 0.04% 0.00%
March 14, 2024 Booth Bruce Not found S Common Stock 781 $41.51 4,629,975.0000 58,365,499 0.02% 0.00%
March 14, 2024 Booth Bruce Not found S Common Stock 7292 $39.73 821,538.0000 58,365,499 0.88% 0.01%
March 14, 2024 Booth Bruce Not found S Common Stock 2233 $40.66 819,305.0000 58,365,499 0.27% 0.00%
March 14, 2024 Booth Bruce Not found S Common stock 154 $41.51 819,151.0000 58,365,499 0.02% 0.00%
March 15, 2024 Booth Bruce Not found S Common Stock 8126 $39.31 4,621,849.0000 58,365,499 0.18% 0.01%
March 15, 2024 Booth Bruce Not found S Common Stock 49591 $40.62 4,572,258.0000 58,365,499 1.07% 0.08%
March 15, 2024 Booth Bruce Not found S Common Stock 1593 $41.23 4,570,665.0000 58,365,499 0.03% 0.00%
March 15, 2024 Booth Bruce Not found S Common Stock 10411 $40.62 807,026.0000 58,365,499 1.27% 0.02%
March 12, 2024 Booth Bruce Not found S Common Stock 8581 $42.52 4,791,165.0000 58,365,499 0.18% 0.01%
March 13, 2024 Booth Bruce Not found S Common Stock 1386 $42.84 828,830.0000 58,365,499 0.17% 0.00%
March 13, 2024 Booth Bruce Not found S Common Stock 22779 $42.19 830,216.0000 58,365,499 2.67% 0.04%
March 13, 2024 Booth Bruce Not found S Common Stock 6686 $42.84 4,676,075.0000 58,365,499 0.14% 0.01%
March 13, 2024 Booth Bruce Not found S Common Stock 108404 $42.19 4,682,761.0000 58,365,499 2.26% 0.19%
March 12, 2024 Booth Bruce Not found S Common Stock 1819 $42.52 852,995.0000 58,365,499 0.21% 0.00%
March 12, 2024 Booth Bruce Not found S Common Stock 26452 $41.94 854,814.0000 58,365,499 3.00% 0.05%
March 12, 2024 Booth Bruce Not found S Common Stock 126066 $41.94 4,799,746.0000 58,365,499 2.56% 0.22%
March 11, 2024 Booth Bruce Not found S Common Stock 1045 $43.42 881,266.0000 58,365,499 0.12% 0.00%
March 11, 2024 Booth Bruce Not found S Common Stock 7837 $42.77 882,311.0000 58,365,499 0.88% 0.01%
March 11, 2024 Booth Bruce Not found S Common Stock 5122 $43.42 4,925,812.0000 58,365,499 0.10% 0.01%
March 11, 2024 Booth Bruce Not found S Common Stock 37180 $42.77 4,930,934.0000 58,365,499 0.75% 0.06%
March 13, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 1386 $42.84 5,504,905.0000 58,365,499 0.03% 0.00%
March 13, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 22779 $42.19 5,506,291.0000 58,365,499 0.41% 0.04%
March 13, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 6686 $42.84 5,504,905.0000 58,365,499 0.12% 0.01%
March 13, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 108404 $42.19 5,511,591.0000 58,365,499 1.93% 0.19%
March 12, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 1819 $42.52 5,529,070.0000 58,365,499 0.03% 0.00%
March 12, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 26452 $41.94 5,530,889.0000 58,365,499 0.48% 0.05%
March 12, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 8581 $42.52 5,619,995.0000 58,365,499 0.15% 0.01%
March 12, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 126066 $41.94 5,628,576.0000 58,365,499 2.19% 0.22%
March 11, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 1045 $43.42 5,557,341.0000 58,365,499 0.02% 0.00%
March 11, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 7837 $42.77 5,558,386.0000 58,365,499 0.14% 0.01%
March 11, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 5122 $43.42 5,754,642.0000 58,365,499 0.09% 0.01%
March 11, 2024 Atlas Venture Fund X, L.P. Not found S Common Stock 37180 $42.77 5,759,764.0000 58,365,499 0.64% 0.06%
March 1, 2024 Chiniara Ellen Chief Legal Officer A Stock Option (Right to Buy) 130531 $0.00 130,531.0000 58,365,499 9999.99% 0.22%
March 1, 2024 Mainolfi Nello Chief Executive Officer A Stock Option (Right to Buy) 530000 $0.00 530,000.0000 58,365,499 9999.99% 0.91%
March 1, 2024 Jacobs Bruce N. Chief Financial Officer A Common Stock 31250 $0.00 146,285.0000 58,365,499 27.17% 0.05%
March 4, 2024 Jacobs Bruce N. Chief Financial Officer S Common Stock 2378 $41.41 143,907.0000 58,365,499 1.63% 0.00%
March 4, 2024 Jacobs Bruce N. Chief Financial Officer S Common Stock 1301 $42.39 142,606.0000 58,365,499 0.90% 0.00%
March 4, 2024 Jacobs Bruce N. Chief Financial Officer S Common Stock 255 $43.26 142,351.0000 58,365,499 0.18% 0.00%
March 1, 2024 Jacobs Bruce N. Chief Financial Officer A Stock Option (Right to Buy) 187500 $0.00 187,500.0000 58,365,499 9999.99% 0.32%
March 1, 2024 Gollob Jared Chief Medical Officer A Common Stock 24375 $0.00 99,084.0000 58,365,499 32.63% 0.04%
March 4, 2024 Gollob Jared Chief Medical Officer S Common Stock 2022 $41.41 97,062.0000 58,365,499 2.04% 0.00%
March 4, 2024 Gollob Jared Chief Medical Officer S Common Stock 1106 $42.39 95,956.0000 58,365,499 1.14% 0.00%
March 4, 2024 Gollob Jared Chief Medical Officer S Common Stock 216 $43.26 95,740.0000 58,365,499 0.23% 0.00%
March 1, 2024 Gollob Jared Chief Medical Officer A Stock Option (Right to Buy) 146250 $0.00 146,250.0000 58,365,499 9999.99% 0.25%
March 1, 2024 Chadwick Jeremy G Chief Operating Officer A Common Stock 13425 $0.00 46,758.0000 58,365,499 40.28% 0.02%
March 1, 2024 Chadwick Jeremy G Chief Operating Officer A Stock Option (Right to Buy) 80548 $0.00 80,548.0000 58,365,499 9999.99% 0.14%
March 1, 2024 Chiniara Ellen Chief Legal Officer A Common Stock 21755 $0.00 55,960.0000 58,365,499 63.60% 0.04%
Feb. 27, 2024 Gollob Jared Chief Medical Officer M Common Stock 400 $2.08 75,109.0000 58,365,499 0.54% 0.00%
Feb. 27, 2024 Gollob Jared Chief Medical Officer S Common Stock 400 $45.00 74,709.0000 58,365,499 0.53% 0.00%
Feb. 27, 2024 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 400 $0.00 62,483.0000 58,365,499 0.64% 0.00%
Feb. 20, 2024 Albers Jeffrey W. Not found S Common Stock 615 $39.07 0.0000 58,365,499 100.00% 0.00%
Feb. 21, 2024 Albers Jeffrey W. Not found S Common Stock 4385 $39.05 0.0000 58,365,499 100.00% 0.01%
Feb. 20, 2024 Albers Jeffrey W. Not found M Stock Option (Right to Buy) 615 $0.00 20,734.0000 58,365,499 2.88% 0.00%
Feb. 21, 2024 Albers Jeffrey W. Not found M Common Stock 4385 $10.34 4,385.0000 58,365,499 9999.99% 0.01%
Feb. 21, 2024 Albers Jeffrey W. Not found M Stock Option (Right to Buy) 4385 $0.00 16,349.0000 58,365,499 21.15% 0.01%
Feb. 20, 2024 Albers Jeffrey W. Not found M Common Stock 615 $10.34 615.0000 58,365,499 9999.99% 0.00%
Feb. 9, 2024 Gollob Jared Chief Medical Officer M Stock Option (Right to Buy) 46137 $0.00 62,883.0000 58,365,499 42.32% 0.08%
Feb. 9, 2024 Gollob Jared Chief Medical Officer S Common Stock 38739 $35.39 82,107.0000 58,365,499 32.06% 0.07%
Feb. 9, 2024 Gollob Jared Chief Medical Officer S Common Stock 7398 $36.09 74,709.0000 58,365,499 9.01% 0.01%
Feb. 9, 2024 Gollob Jared Chief Medical Officer M Common Stock 46137 $2.08 120,846.0000 58,365,499 61.76% 0.08%
Jan. 23, 2024 Albers Jeffrey W. Not found S Common Stock 10000 $30.05 0.0000 58,365,499 100.00% 0.02%
Jan. 23, 2024 Albers Jeffrey W. Not found M Common Stock 10000 $10.34 10,000.0000 58,365,499 9999.99% 0.02%
Jan. 23, 2024 Albers Jeffrey W. Not found M Stock Option (Right to Buy) 10000 $0.00 21,349.0000 58,365,499 31.90% 0.02%
Jan. 5, 2024 BVF PARTNERS L P/IL Other P Pre-Funded Warrants to Purchase Common Stock 52733 $25.25 52,733.0000 58,365,499 9999.99% 0.09%
Jan. 5, 2024 BVF PARTNERS L P/IL Other P Pre-Funded Warrants to Purchase Common Stock 375856 $25.25 375,856.0000 58,365,499 9999.99% 0.64%
Jan. 5, 2024 BVF PARTNERS L P/IL Other P Pre-Funded Warrants to Purchase Common Stock 550425 $25.25 550,425.0000 58,365,499 9999.99% 0.94%
Jan. 4, 2024 Chiniara Ellen Chief Legal Officer S Common Stock 3295 $22.58 34,205.0000 58,365,499 8.79% 0.01%
Jan. 2, 2024 Mainolfi Nello Chief Executive Officer M Common Stock 9000 $2.08 615,570.0000 58,365,499 1.48% 0.02%
Jan. 2, 2024 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 9000 $0.00 519,972.0000 58,365,499 1.70% 0.02%
Nov. 2, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 26772 $11.64 284,526.0000 53,933,229 10.39% 0.05%
Nov. 2, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 57618 $11.64 2,552,306.0000 53,933,229 2.31% 0.11%
Nov. 3, 2023 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 17632 $0.00 528,972.0000 53,933,229 3.23% 0.03%
Nov. 3, 2023 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 2368 $0.00 0.0000 53,933,229 100.00% 0.00%
Nov. 3, 2023 Mainolfi Nello Chief Executive Officer M Common Stock 17632 $2.08 606,570.0000 53,933,229 2.99% 0.03%
Nov. 3, 2023 Mainolfi Nello Chief Executive Officer M Common Stock 2368 $2.08 588,938.0000 53,933,229 0.40% 0.00%
Nov. 3, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 10106 $14.07 294,632.0000 53,933,229 3.55% 0.02%
Nov. 3, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 83708 $14.07 2,104,075.0000 53,933,229 4.14% 0.16%
Nov. 3, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 103885 $14.07 2,656,191.0000 53,933,229 4.07% 0.19%
Nov. 2, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 132016 $11.64 2,020,367.0000 53,933,229 6.99% 0.24%
Aug. 8, 2023 Mainolfi Nello Chief Executive Officer M Common Stock 12000 $2.08 586,570.0000 53,933,229 2.09% 0.02%
Aug. 8, 2023 Mainolfi Nello Chief Executive Officer M Stock Option (Right to Buy) 12000 $0.00 2,368.0000 53,933,229 83.52% 0.02%
June 15, 2023 MARAGANORE JOHN Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 15, 2023 Morgan Leigh Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 15, 2023 BVF PARTNERS L P/IL Other A Stock Option (Right to Buy) 12000 $0.00 84,190.0000 53,933,229 16.62% 0.02%
June 15, 2023 Sandor Victor Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 15, 2023 Booth Bruce Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 15, 2023 Ridloff Elena Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 15, 2023 Hrustanovic Gorjan Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 15, 2023 Esposito Pamela Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 15, 2023 Albers Jeffrey W. Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 15, 2023 Horobin Joanna Director A Stock Option (Right to Buy) 12000 $0.00 12,000.0000 53,933,229 9999.99% 0.02%
June 2, 2023 Jacobs Bruce N. Chief Financial Officer M Stock Option (Right to Buy) 10000 $0.00 129,899.0000 53,933,229 8.34% 0.02%
June 2, 2023 Jacobs Bruce N. Chief Financial Officer M Common Stock 10000 $2.08 115,035.0000 53,933,229 9.52% 0.02%
May 22, 2023 Chadwick Jeremy G Chief Operating Officer A Stock Option (Right to Buy) 200000 $0.00 200,000.0000 53,933,229 9999.99% 0.37%
May 22, 2023 Chadwick Jeremy G Chief Operating Officer A Common Stock 33333 $0.00 33,333.0000 53,933,229 9999.99% 0.06%
March 2, 2023 Caughey Elaine Chief Business Officer S Common Stock 550 $30.88 19,150.0000 53,933,229 2.79% 0.00%
March 2, 2023 Gollob Jared Chief Medical Officer S Common Stock 1001 $30.88 75,006.0000 53,933,229 1.32% 0.00%
March 1, 2023 Gollob Jared Chief Medical Officer A Common Stock 18750 $0.00 76,007.0000 53,933,229 32.75% 0.03%
March 1, 2023 Caughey Elaine Chief Business Officer A Stock Option (Right to Buy) 63338 $0.00 63,338.0000 53,933,229 9999.99% 0.12%
March 2, 2023 Caughey Elaine Chief Business Officer S Common Stock 164 $31.40 18,986.0000 53,933,229 0.86% 0.00%
March 2, 2023 Gollob Jared Chief Medical Officer S Common Stock 297 $31.40 74,709.0000 53,933,229 0.40% 0.00%
March 1, 2023 Caughey Elaine Chief Business Officer A Common Stock 10557 $0.00 19,700.0000 53,933,229 115.47% 0.02%
March 1, 2023 Mainolfi Nello Chief Executive Officer A Stock Option (Right to Buy) 450000 $0.00 450,000.0000 53,933,229 9999.99% 0.83%
March 1, 2023 Jacobs Bruce N. Chief Financial Officer A Stock Option (Right to Buy) 142500 $0.00 142,500.0000 53,933,229 9999.99% 0.26%
March 2, 2023 Jacobs Bruce N. Chief Financial Officer S Common Stock 314 $31.40 104,568.0000 53,933,229 0.30% 0.00%
March 2, 2023 Jacobs Bruce N. Chief Financial Officer S Common Stock 1056 $30.88 104,882.0000 53,933,229 1.00% 0.00%
March 1, 2023 Jacobs Bruce N. Chief Financial Officer A Common Stock 23750 $0.00 105,938.0000 53,933,229 28.90% 0.04%
March 1, 2023 Gollob Jared Chief Medical Officer A Stock Option (Right to Buy) 112500 $0.00 112,500.0000 53,933,229 9999.99% 0.21%
Jan. 12, 2023 Atlas Venture Fund X, L.P. TenPercentOwner S Common Stock 21592 $30.29 5,858,262.0000 53,933,229 0.37% 0.04%
Jan. 12, 2023 Booth Bruce Director S Common Stock 77128 $30.29 4,968,114.0000 53,933,229 1.53% 0.14%
Jan. 11, 2023 Booth Bruce Director S Common Stock 6071 $29.96 911,740.0000 53,933,229 0.66% 0.01%
Jan. 11, 2023 Booth Bruce Director S Common Stock 21683 $29.96 5,045,242.0000 53,933,229 0.43% 0.04%
Jan. 12, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 15912 $31.24 2,146,105.0000 53,933,229 0.75% 0.03%
Jan. 11, 2023 Atlas Venture Fund X, L.P. TenPercentOwner S Common Stock 6071 $29.96 5,879,854.0000 53,933,229 0.10% 0.01%
Jan. 12, 2023 Atlas Venture Fund X, L.P. TenPercentOwner S Common Stock 77128 $30.29 5,858,262.0000 53,933,229 1.30% 0.14%
Jan. 12, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 2985 $31.24 2,752,442.0000 53,933,229 0.11% 0.01%
Jan. 11, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 11149 $29.89 2,130,193.0000 53,933,229 0.53% 0.02%
Jan. 11, 2023 BVF PARTNERS L P/IL Other P Common Stock, $0.0001 par value 10961 $29.89 2,749,457.0000 53,933,229 0.40% 0.02%
Jan. 12, 2023 Booth Bruce Director S Common Stock 21592 $30.29 890,148.0000 53,933,229 2.37% 0.04%
Jan. 11, 2023 Atlas Venture Fund X, L.P. TenPercentOwner S Common Stock 21683 $29.96 5,935,390.0000 53,933,229 0.36% 0.04%
Jan. 3, 2023 Chiniara Ellen Chief Legal Officer A Stock Option (Right to Buy) 225000 $0.00 225,000.0000 53,933,229 9999.99% 0.42%
Jan. 3, 2023 Chiniara Ellen Chief Legal Officer A Common Stock 37500 $0.00 37,500.0000 53,933,229 9999.99% 0.07%