In the last 12 months, insiders at Prime Medicine, Inc. ($PRME) filed 191 transactions with the SEC: 14 open-market purchases totaling $95,396,927 and 33 sales totaling $20,007,709. Net insider sentiment: net buying.
Prime Medicine, Inc. operates in the Biological products, (no disgnostic substances) industry (Life sciences sector).
Most Active Insiders
- ARCH Venture Partners XII, LLC (TenPercentOwner) — 2 transactions totaling $29,999,990
- NELSEN ROBERT (Director) — 9 transactions totaling $29,999,990
- ARCH Venture Partners X, LLC (TenPercentOwner) — 2 transactions totaling $29,999,990
- GV 2019 GP, L.L.C. (TenPercentOwner) — 55 transactions totaling $20,007,709
- GV 2021 GP, L.L.C. (Not found) — 1 transaction totaling $4,950,000
View all SEC Filings for Prime Medicine, Inc. (PRME).
Set Up your own filters →Recent Insider Transactions
| Transaction Date | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|
| Feb. 26, 2026 | Reine Allan | Chief Executive Officer | A | Stock Option (right to buy) | 1300000 | $0.00 | 1,300,000.0000 | 180,510,658 | 9999.99% | 0.72% |
| Feb. 23, 2026 | LEE ANN L. | Chief Technical Officer | A | Stock Option (right to buy) | 375000 | $0.00 | 375,000.0000 | 180,510,658 | 9999.99% | 0.21% |
| Feb. 23, 2026 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 140000 | $0.00 | 140,000.0000 | 180,510,658 | 9999.99% | 0.08% |
| Aug. 1, 2025 | Schenkein David P | Director | D | Stock Option (right to buy) | 45000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Schenkein David P | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | NELSEN ROBERT | Director | D | Stock Option (right to buy) | 39062 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | NELSEN ROBERT | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | NELSEN ROBERT | Director | D | Stock Option (right to buy) | 45000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | NELSEN ROBERT | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Marrazzo Jeffrey D | Director | D | Stock Option (right to buy) | 92000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.07% |
| Aug. 1, 2025 | Marrazzo Jeffrey D | Director | A | Stock Option (right to buy) | 92000 | $0.00 | 92,000.0000 | 131,160,842 | 9999.99% | 0.07% |
| Aug. 1, 2025 | Marrazzo Jeffrey D | Director | D | Stock Option (right to buy) | 250000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.19% |
| Aug. 1, 2025 | Marrazzo Jeffrey D | Director | A | Stock Option (right to buy) | 250000 | $0.00 | 250,000.0000 | 131,160,842 | 9999.99% | 0.19% |
| Aug. 1, 2025 | Marrazzo Jeffrey D | Director | D | Stock Option (right to buy) | 45000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Marrazzo Jeffrey D | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Kelly Michael Aaron | Director | D | Stock Option (right to buy) | 13510 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.01% |
| Aug. 1, 2025 | Kelly Michael Aaron | Director | A | Stock Option (right to buy) | 13510 | $0.00 | 13,510.0000 | 131,160,842 | 9999.99% | 0.01% |
| Aug. 1, 2025 | Kelly Michael Aaron | Director | D | Stock Option (right to buy) | 9006 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.01% |
| Aug. 1, 2025 | Kelly Michael Aaron | Director | A | Stock Option (right to buy) | 9006 | $0.00 | 9,006.0000 | 131,160,842 | 9999.99% | 0.01% |
| Aug. 1, 2025 | Schenkein David P | Director | D | Stock Option (right to buy) | 39062 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Kelly Michael Aaron | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Kelly Michael Aaron | Director | D | Stock Option (right to buy) | 45000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Kelly Michael Aaron | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Foster-Cheek Kaye I | Director | D | Stock Option (right to buy) | 13510 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.01% |
| Aug. 1, 2025 | Foster-Cheek Kaye I | Director | A | Stock Option (right to buy) | 13510 | $0.00 | 13,510.0000 | 131,160,842 | 9999.99% | 0.01% |
| Aug. 1, 2025 | Foster-Cheek Kaye I | Director | D | Stock Option (right to buy) | 9006 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.01% |
| Aug. 1, 2025 | Foster-Cheek Kaye I | Director | A | Stock Option (right to buy) | 9006 | $0.00 | 9,006.0000 | 131,160,842 | 9999.99% | 0.01% |
| Aug. 1, 2025 | Foster-Cheek Kaye I | Director | D | Stock Option (right to buy) | 39062 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Foster-Cheek Kaye I | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Foster-Cheek Kaye I | Director | D | Stock Option (right to buy) | 45000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Foster-Cheek Kaye I | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Chung Wendy | Director | D | Stock Option (right to buy) | 13510 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.01% |
| Aug. 1, 2025 | Chung Wendy | Director | A | Stock Option (right to buy) | 13510 | $0.00 | 13,510.0000 | 131,160,842 | 9999.99% | 0.01% |
| Aug. 1, 2025 | Chung Wendy | Director | D | Stock Option (right to buy) | 9006 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.01% |
| Aug. 1, 2025 | Chung Wendy | Director | A | Stock Option (right to buy) | 9006 | $0.00 | 9,006.0000 | 131,160,842 | 9999.99% | 0.01% |
| Aug. 1, 2025 | Chung Wendy | Director | D | Stock Option (right to buy) | 39062 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Chung Wendy | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Chung Wendy | Director | D | Stock Option (right to buy) | 45000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Chung Wendy | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Cahill Thomas | Director | D | Stock Option (right to buy) | 39062 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Cahill Thomas | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Cahill Thomas | Director | D | Stock Option (right to buy) | 45000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | Cahill Thomas | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | Reine Allan | Chief Executive Officer | D | Stock Option (right to buy) | 850000 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.65% |
| Aug. 1, 2025 | Reine Allan | Chief Executive Officer | A | Stock Option (right to buy) | 850000 | $0.00 | 850,000.0000 | 131,160,842 | 9999.99% | 0.65% |
| Aug. 1, 2025 | Alenson Carman | See Remarks | D | Stock Option (right to buy) | 16083 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.01% |
| Aug. 1, 2025 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 16083 | $0.00 | 16,083.0000 | 131,160,842 | 9999.99% | 0.01% |
| Aug. 1, 2025 | Alenson Carman | See Remarks | D | Stock Option (right to buy) | 90498 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.07% |
| Aug. 1, 2025 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 90498 | $0.00 | 90,498.0000 | 131,160,842 | 9999.99% | 0.07% |
| Aug. 1, 2025 | Alenson Carman | See Remarks | D | Stock Option (right to buy) | 6254 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.00% |
| Aug. 1, 2025 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 6254 | $0.00 | 6,254.0000 | 131,160,842 | 9999.99% | 0.00% |
| Aug. 1, 2025 | Alenson Carman | See Remarks | D | Stock Option (right to buy) | 90498 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.07% |
| Aug. 1, 2025 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 90498 | $0.00 | 90,498.0000 | 131,160,842 | 9999.99% | 0.07% |
| Aug. 1, 2025 | GV 2021 GP, L.L.C. | Not found | P | Common Stock | 1500000 | $3.30 | 3,262,440.0000 | 131,160,842 | 85.11% | 1.14% |
| Aug. 1, 2025 | Kelly Michael Aaron | Director | D | Stock Option (right to buy) | 39062 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.03% |
| Aug. 1, 2025 | LEE ANN L. | Chief Technical Officer | D | Stock Option (right to buy) | 180995 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.14% |
| Aug. 1, 2025 | Schenkein David P | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 131,160,842 | 9999.99% | 0.03% |
| Aug. 1, 2025 | LEE ANN L. | Chief Technical Officer | A | Stock Option (right to buy) | 180995 | $0.00 | 180,995.0000 | 131,160,842 | 9999.99% | 0.14% |
| Aug. 1, 2025 | LEE ANN L. | Chief Technical Officer | D | Stock Option (right to buy) | 180995 | $0.00 | 0.0000 | 131,160,842 | 100.00% | 0.14% |
| Aug. 1, 2025 | LEE ANN L. | Chief Technical Officer | A | Stock Option (right to buy) | 180995 | $0.00 | 180,995.0000 | 131,160,842 | 9999.99% | 0.14% |
| Aug. 1, 2025 | NELSEN ROBERT | Director | P | Common Stock | 3030300 | $3.30 | 18,502,974.0000 | 131,160,842 | 19.58% | 2.31% |
| Aug. 1, 2025 | ARCH Venture Partners X, LLC | TenPercentOwner | P | Common Stock | 3030300 | $3.30 | 18,486,894.0000 | 131,160,842 | 19.61% | 2.31% |
| Aug. 1, 2025 | ARCH Venture Partners XII, LLC | TenPercentOwner | P | Common Stock | 3030300 | $3.30 | 18,486,894.0000 | 131,160,842 | 19.61% | 2.31% |
| June 30, 2025 | Liu David R. | TenPercentOwner | P | Common Stock | 21000 | $2.52 | 20,240,945.0000 | 131,160,842 | 0.10% | 0.02% |
| June 23, 2025 | Liu David R. | TenPercentOwner | P | Common Stock | 21000 | $2.16 | 20,219,945.0000 | 131,160,842 | 0.10% | 0.02% |
| June 16, 2025 | Liu David R. | TenPercentOwner | P | Common Stock | 21000 | $1.49 | 20,198,945.0000 | 131,160,842 | 0.10% | 0.02% |
| June 11, 2025 | Liu David R. | TenPercentOwner | P | Common Stock | 21000 | $1.60 | 20,177,945.0000 | 131,160,842 | 0.10% | 0.02% |
| June 4, 2025 | Kelly Michael Aaron | Director | A | Stock Option (right to buy) | 55000 | $0.00 | 55,000.0000 | 131,160,842 | 9999.99% | 0.04% |
| June 4, 2025 | Foster-Cheek Kaye I | Director | A | Stock Option (right to buy) | 55000 | $0.00 | 55,000.0000 | 131,160,842 | 9999.99% | 0.04% |
| June 4, 2025 | Chung Wendy | Director | A | Stock Option (right to buy) | 55000 | $0.00 | 55,000.0000 | 131,160,842 | 9999.99% | 0.04% |
| June 4, 2025 | Cahill Thomas | Director | A | Stock Option (right to buy) | 55000 | $0.00 | 55,000.0000 | 131,160,842 | 9999.99% | 0.04% |
| June 4, 2025 | Schenkein David P | Director | A | Stock Option (right to buy) | 55000 | $0.00 | 55,000.0000 | 131,160,842 | 9999.99% | 0.04% |
| June 4, 2025 | Marrazzo Jeffrey D | Director | A | Stock Option (right to buy) | 55000 | $0.00 | 55,000.0000 | 131,160,842 | 9999.99% | 0.04% |
| June 4, 2025 | NELSEN ROBERT | Director | A | Stock Option (right to buy) | 55000 | $0.00 | 55,000.0000 | 131,160,842 | 9999.99% | 0.04% |
| May 21, 2025 | LEE ANN L. | Chief Technical Officer | P | Common Stock | 100000 | $1.13 | 100,000.0000 | 131,160,842 | 9999.99% | 0.08% |
| May 21, 2025 | Reine Allan | Chief Executive Officer | P | Common Stock | 125000 | $1.18 | 125,000.0000 | 131,160,842 | 9999.99% | 0.10% |
| May 20, 2025 | Brudnick Richard | Chief Business Officer | P | Common Stock | 20000 | $1.19 | 20,000.0000 | 131,160,842 | 9999.99% | 0.02% |
| May 19, 2025 | Marrazzo Jeffrey D | Director | A | Stock Option (right to buy) | 800000 | $0.00 | 800,000.0000 | 131,160,842 | 9999.99% | 0.61% |
| May 19, 2025 | Reine Allan | Chief Executive Officer | A | Stock Option (right to buy) | 2000000 | $0.00 | 2,000,000.0000 | 131,160,842 | 9999.99% | 1.52% |
| May 8, 2025 | LEE ANN L. | Chief Technical Officer | A | Stock Option (right to buy) | 80416 | $0.00 | 241,248.0000 | 131,160,842 | 50.00% | 0.06% |
| May 8, 2025 | Reine Allan | Chief Financial Officer | A | Stock Option (right to buy) | 75000 | $0.00 | 850,000.0000 | 131,160,842 | 9.68% | 0.06% |
| May 8, 2025 | Gottesdiener Keith Michael | See Remarks | A | Stock Option (right to buy) | 100000 | $0.00 | 300,000.0000 | 131,160,842 | 50.00% | 0.08% |
| Feb. 28, 2025 | Gottesdiener Keith Michael | See Remarks | A | Stock Option (right to buy) | 500000 | $0.00 | 500,000.0000 | 131,160,842 | 9999.99% | 0.38% |
| Feb. 27, 2025 | LEE ANN L. | Chief Technical Officer | A | Stock Option (right to buy) | 275000 | $0.00 | 275,000.0000 | 131,160,842 | 9999.99% | 0.21% |
| Feb. 27, 2025 | Brudnick Richard | Chief Business Officer | A | Stock Option (right to buy) | 225000 | $0.00 | 225,000.0000 | 131,160,842 | 9999.99% | 0.17% |
| Feb. 27, 2025 | Reine Allan | Chief Financial Officer | A | Stock Option (right to buy) | 275000 | $0.00 | 275,000.0000 | 131,160,842 | 9999.99% | 0.21% |
| Feb. 27, 2025 | Duffield Jeremy | Chief Scientific Officer | A | Stock Option (right to buy) | 275000 | $0.00 | 275,000.0000 | 131,160,842 | 9999.99% | 0.21% |
| Feb. 27, 2025 | Goldwasser Meredith | SVP, Strategy & Corporate Ops. | A | Stock Option (right to buy) | 90500 | $0.00 | 90,500.0000 | 131,160,842 | 9999.99% | 0.07% |
| Feb. 27, 2025 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 90500 | $0.00 | 90,500.0000 | 131,160,842 | 9999.99% | 0.07% |
| Dec. 5, 2024 | Gottesdiener Keith Michael | See Remarks | A | Stock Option (right to buy) | 100000 | $0.00 | 200,000.0000 | 0 | 100.00% | 0.00% |
| Dec. 5, 2024 | Brudnick Richard | Chief Business Officer | A | Stock Option (right to buy) | 19300 | $0.00 | 57,900.0000 | 0 | 50.00% | 0.00% |
| Dec. 5, 2024 | Reine Allan | Chief Financial Officer | A | Stock Option (right to buy) | 75000 | $0.00 | 775,000.0000 | 0 | 10.71% | 0.00% |
| Oct. 8, 2024 | Gottesdiener Keith Michael | See Remarks | G | Common Stock | 226925 | $0.00 | 4,361,078.0000 | 0 | 4.95% | 0.00% |
| Oct. 8, 2024 | Gottesdiener Keith Michael | See Remarks | G | Common Stock | 226925 | $0.00 | 4,361,078.0000 | 0 | 5.49% | 0.00% |
| June 12, 2024 | Foster-Cheek Kaye I | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Marrazzo Jeffrey D | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Schenkein David P | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | NELSEN ROBERT | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Kelly Michael Aaron | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Chung Wendy | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Cahill Thomas | Director | A | Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 0 | 9999.99% | 0.00% |
| June 5, 2024 | Gottesdiener Keith Michael | See Remarks | G | Common Stock | 250000 | $0.00 | 4,361,078.0000 | 0 | 5.42% | 0.00% |
| June 5, 2024 | Gottesdiener Keith Michael | See Remarks | G | Common Stock | 250000 | $0.00 | 4,361,078.0000 | 0 | 6.08% | 0.00% |
| May 17, 2024 | Reine Allan | Chief Financial Officer | A | Stock Option (right to buy) | 100000 | $0.00 | 100,000.0000 | 0 | 9999.99% | 0.00% |
| May 17, 2024 | Brudnick Richard | Chief Business Officer | A | Stock Option (right to buy) | 19300 | $0.00 | 38,600.0000 | 0 | 100.00% | 0.00% |
| May 17, 2024 | LEE ANN L. | Chief Technical Officer | A | Stock Option (right to buy) | 80416 | $0.00 | 160,832.0000 | 0 | 100.00% | 0.00% |
| Feb. 29, 2024 | Marrazzo Jeffrey D | Director | A | Stock Option (right to buy) | 250000 | $0.00 | 250,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 25, 2024 | Gottesdiener Keith Michael | See Remarks | A | Stock Option (right to buy) | 100000 | $0.00 | 100,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 21, 2024 | Goldwasser Meredith | SVP, Strategy & Corporate Ops. | A | Stock Option (right to buy) | 90498 | $0.00 | 90,498.0000 | 0 | 9999.99% | 0.00% |
| Feb. 21, 2024 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 90498 | $0.00 | 90,498.0000 | 0 | 9999.99% | 0.00% |
| Feb. 21, 2024 | Duffield Jeremy | Chief Scientific Officer | A | Stock Option (right to buy) | 180995 | $0.00 | 180,995.0000 | 0 | 9999.99% | 0.00% |
| Feb. 21, 2024 | Brudnick Richard | Chief Business Officer | A | Stock Option (right to buy) | 135747 | $0.00 | 135,747.0000 | 0 | 9999.99% | 0.00% |
| Feb. 21, 2024 | LEE ANN L. | Chief Technical Officer | A | Stock Option (right to buy) | 180995 | $0.00 | 180,995.0000 | 0 | 9999.99% | 0.00% |
| Feb. 15, 2024 | NELSEN ROBERT | Director | P | Common Stock | 3200000 | $6.25 | 15,472,674.0000 | 0 | 26.07% | 0.00% |
| Feb. 15, 2024 | ARCH Venture Partners XII, LLC | TenPercentOwner | P | Common Stock | 3200000 | $6.25 | 15,456,594.0000 | 0 | 26.11% | 0.00% |
| Feb. 15, 2024 | ARCH Venture Partners X, LLC | TenPercentOwner | P | Common Stock | 3200000 | $6.25 | 15,456,594.0000 | 0 | 26.11% | 0.00% |
| Jan. 17, 2024 | Reine Allan | Chief Financial Officer | A | Stock Option (right to buy) | 600000 | $0.00 | 600,000.0000 | 0 | 9999.99% | 0.00% |
| Nov. 11, 2023 | Gottesdiener Keith Michael | See Remarks | G | Common Stock | 5000 | $0.00 | 4,361,078.0000 | 0 | 0.11% | 0.00% |
| Nov. 11, 2023 | Gottesdiener Keith Michael | See Remarks | G | Common Stock | 7500 | $0.00 | 4,361,078.0000 | 0 | 0.17% | 0.00% |
| July 21, 2023 | Liu David R. | TenPercentOwner | G | Common Stock | 1000000 | $0.00 | 20,156,945.0000 | 0 | 4.73% | 0.00% |
| July 21, 2023 | Liu David R. | TenPercentOwner | G | Common Stock | 1000000 | $0.00 | 20,156,945.0000 | 0 | 4.73% | 0.00% |
| June 21, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 19003 | $0.00 | 11,862,498.0000 | 0 | 0.16% | 0.00% |
| June 21, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 19003 | $14.97 | 11,862,498.0000 | 0 | 0.16% | 0.00% |
| June 20, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 37405 | $15.06 | 11,862,498.0000 | 0 | 0.31% | 0.00% |
| June 20, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 37405 | $0.00 | 11,881,501.0000 | 0 | 0.31% | 0.00% |
| June 15, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 66659 | $14.92 | 11,918,906.0000 | 0 | 0.56% | 0.00% |
| June 16, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 6532 | $0.00 | 11,918,906.0000 | 0 | 0.05% | 0.00% |
| June 16, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 6532 | $15.02 | 11,918,906.0000 | 0 | 0.05% | 0.00% |
| June 15, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 66659 | $0.00 | 11,925,438.0000 | 0 | 0.56% | 0.00% |
| June 14, 2023 | Chung Wendy | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 0 | 9999.99% | 0.00% |
| June 14, 2023 | Cahill Thomas | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 0 | 9999.99% | 0.00% |
| June 14, 2023 | Schenkein David P | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 0 | 9999.99% | 0.00% |
| June 14, 2023 | Foster-Cheek Kaye I | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 0 | 9999.99% | 0.00% |
| June 14, 2023 | NELSEN ROBERT | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 0 | 9999.99% | 0.00% |
| June 14, 2023 | Kelly Michael Aaron | Director | A | Stock Option (right to buy) | 39062 | $0.00 | 39,062.0000 | 0 | 9999.99% | 0.00% |
| June 13, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 28100 | $0.00 | 12,021,057.0000 | 0 | 0.23% | 0.00% |
| June 13, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 28100 | $15.13 | 11,992,097.0000 | 0 | 0.23% | 0.00% |
| June 14, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 28960 | $0.00 | 11,992,097.0000 | 0 | 0.24% | 0.00% |
| June 14, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 28960 | $14.87 | 11,992,097.0000 | 0 | 0.24% | 0.00% |
| June 9, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 15672 | $0.00 | 12,065,188.0000 | 0 | 0.13% | 0.00% |
| June 9, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 15672 | $14.48 | 12,049,157.0000 | 0 | 0.13% | 0.00% |
| June 12, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 16031 | $0.00 | 12,049,157.0000 | 0 | 0.13% | 0.00% |
| June 12, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 16031 | $14.98 | 12,049,157.0000 | 0 | 0.13% | 0.00% |
| June 8, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 5000 | $15.74 | 12,080,860.0000 | 0 | 0.04% | 0.00% |
| June 8, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 5000 | $0.00 | 12,080,860.0000 | 0 | 0.04% | 0.00% |
| June 7, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 15000 | $16.92 | 12,080,860.0000 | 0 | 0.12% | 0.00% |
| June 7, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 15000 | $0.00 | 12,085,860.0000 | 0 | 0.12% | 0.00% |
| June 6, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 29975 | $17.02 | 12,100,860.0000 | 0 | 0.25% | 0.00% |
| June 5, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 22434 | $0.00 | 12,130,835.0000 | 0 | 0.18% | 0.00% |
| June 5, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 22434 | $16.70 | 12,100,860.0000 | 0 | 0.19% | 0.00% |
| June 6, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 29975 | $0.00 | 12,100,860.0000 | 0 | 0.25% | 0.00% |
| June 1, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 471 | $14.75 | 12,153,269.0000 | 0 | 0.00% | 0.00% |
| June 1, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 44752 | $14.35 | 12,153,740.0000 | 0 | 0.37% | 0.00% |
| June 1, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 45223 | $0.00 | 12,153,269.0000 | 0 | 0.37% | 0.00% |
| May 31, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 16633 | $13.65 | 12,153,269.0000 | 0 | 0.14% | 0.00% |
| May 31, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 16633 | $0.00 | 12,198,492.0000 | 0 | 0.14% | 0.00% |
| May 30, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 16805 | $13.70 | 12,215,125.0000 | 0 | 0.14% | 0.00% |
| May 30, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 16805 | $0.00 | 12,215,125.0000 | 0 | 0.14% | 0.00% |
| May 26, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 12602 | $13.70 | 12,215,125.0000 | 0 | 0.10% | 0.00% |
| May 26, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 12602 | $0.00 | 12,231,930.0000 | 0 | 0.10% | 0.00% |
| May 24, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 7900 | $0.00 | 12,267,693.0000 | 0 | 0.06% | 0.00% |
| May 24, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 7900 | $13.66 | 12,244,532.0000 | 0 | 0.06% | 0.00% |
| May 25, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 23161 | $0.00 | 12,244,532.0000 | 0 | 0.19% | 0.00% |
| May 25, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 23161 | $13.38 | 12,244,532.0000 | 0 | 0.19% | 0.00% |
| May 22, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 87922 | $0.00 | 12,319,532.0000 | 0 | 0.71% | 0.00% |
| May 22, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 87922 | $14.13 | 12,275,593.0000 | 0 | 0.71% | 0.00% |
| May 23, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 43939 | $0.00 | 12,275,593.0000 | 0 | 0.36% | 0.00% |
| May 23, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 43939 | $14.74 | 12,275,593.0000 | 0 | 0.36% | 0.00% |
| May 19, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 63212 | $13.88 | 12,407,454.0000 | 0 | 0.51% | 0.00% |
| May 18, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 13076 | $13.01 | 12,484,688.0000 | 0 | 0.10% | 0.00% |
| May 18, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 14022 | $0.00 | 12,470,666.0000 | 0 | 0.11% | 0.00% |
| May 18, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 14022 | $13.06 | 12,407,454.0000 | 0 | 0.11% | 0.00% |
| May 19, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | J | Common Stock | 63212 | $0.00 | 12,407,454.0000 | 0 | 0.51% | 0.00% |
| May 16, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 50649 | $12.59 | 12,512,764.0000 | 0 | 0.40% | 0.00% |
| May 17, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 15000 | $12.77 | 12,497,764.0000 | 0 | 0.12% | 0.00% |
| May 12, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 27290 | $12.72 | 12,721,365.0000 | 0 | 0.21% | 0.00% |
| May 15, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 157952 | $12.74 | 12,563,413.0000 | 0 | 1.24% | 0.00% |
| May 10, 2023 | Marrazzo Jeffrey D | Director | A | Stock Option (right to buy) | 92000 | $0.00 | 92,000.0000 | 0 | 9999.99% | 0.00% |
| May 10, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 87397 | $14.03 | 12,775,281.0000 | 0 | 0.68% | 0.00% |
| May 11, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 21819 | $12.98 | 12,753,462.0000 | 0 | 0.17% | 0.00% |
| May 11, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 4807 | $13.79 | 12,748,655.0000 | 0 | 0.04% | 0.00% |
| May 9, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 321238 | $14.08 | 12,862,678.0000 | 0 | 2.44% | 0.00% |
| May 8, 2023 | GV 2019 GP, L.L.C. | TenPercentOwner | S | Common Stock | 100772 | $14.13 | 13,183,916.0000 | 0 | 0.76% | 0.00% |
| April 18, 2023 | Goldwasser Meredith | SVP, Strategy & Corporate Ops. | A | Stock Option (right to buy) | 4690 | $0.00 | 4,690.0000 | 0 | 9999.99% | 0.00% |
| April 18, 2023 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 6254 | $0.00 | 6,254.0000 | 0 | 9999.99% | 0.00% |
| March 31, 2023 | LEE ANN L. | Chief Technical Officer | A | Stock Option (right to buy) | 180995 | $0.00 | 180,995.0000 | 0 | 9999.99% | 0.00% |
| March 31, 2023 | Goldwasser Meredith | SVP, Strategy & Corporate Ops. | A | Stock Option (right to buy) | 90498 | $0.00 | 90,498.0000 | 0 | 9999.99% | 0.00% |
| March 31, 2023 | Alenson Carman | See Remarks | A | Stock Option (right to buy) | 90498 | $0.00 | 90,498.0000 | 0 | 9999.99% | 0.00% |
| March 31, 2023 | Duffield Jeremy | Chief Scientific Officer | A | Stock Option (right to buy) | 180995 | $0.00 | 180,995.0000 | 0 | 9999.99% | 0.00% |
| March 31, 2023 | Brudnick Richard | Chief Business Officer | A | Stock Option (right to buy) | 135747 | $0.00 | 135,747.0000 | 0 | 9999.99% | 0.00% |
| March 31, 2023 | Gottesdiener Keith Michael | See Remarks | A | Stock Option (right to buy) | 497738 | $0.00 | 497,738.0000 | 0 | 9999.99% | 0.00% |