In the last 12 months, insiders at Septerna, Inc. ($SEPN) filed 74 transactions with the SEC: 19 open-market purchases totaling $93,974,853 and 5 sales totaling $2,158,922. Net insider sentiment: net buying.
Septerna, Inc. operates in the Pharmaceutical preparations industry (Life sciences sector).
Most Active Insiders
- RA CAPITAL MANAGEMENT, L.P. (Not found) — 7 transactions totaling $75,060,000
- Third Rock Ventures V, L.P. (Not found) — 6 transactions totaling $11,700,000
- Third Rock Ventures VI, L.P. (Not found) — 3 transactions totaling $6,280,525
- Shaikhly Samira (Chief People Officer) — 10 transactions totaling $2,109,295
- Ezekowitz Alan (Not found) — 5 transactions totaling $608,204
View all SEC Filings for Septerna, Inc. (SEPN).
Set Up your own filters →Recent Insider Transactions
| Transaction Date | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|
| March 2, 2026 | Shaikhly Samira | Chief People Officer | S | Common Stock | 4090 | $27.51 | 67,156.0000 | 45,602,099 | 5.74% | 0.01% |
| March 2, 2026 | Shaikhly Samira | Chief People Officer | M | Stock Option (Right to Buy) | 5101 | $0.00 | 5,101.0000 | 45,602,099 | 50.00% | 0.01% |
| March 2, 2026 | Shaikhly Samira | Chief People Officer | M | Stock Option (Right to Buy) | 11638 | $0.00 | 3,460.0000 | 45,602,099 | 77.08% | 0.03% |
| March 2, 2026 | Shaikhly Samira | Chief People Officer | M | Stock Option (Right to Buy) | 53714 | $0.00 | 15,969.0000 | 45,602,099 | 77.08% | 0.12% |
| March 2, 2026 | Shaikhly Samira | Chief People Officer | S | Common Stock | 66363 | $28.14 | 793.0000 | 45,602,099 | 98.82% | 0.15% |
| March 2, 2026 | Shaikhly Samira | Chief People Officer | M | Common Stock | 53714 | $1.55 | 54,507.0000 | 45,602,099 | 6773.52% | 0.12% |
| March 2, 2026 | Shaikhly Samira | Chief People Officer | M | Common Stock | 11638 | $2.76 | 66,145.0000 | 45,602,099 | 21.35% | 0.03% |
| March 2, 2026 | Shaikhly Samira | Chief People Officer | M | Common Stock | 5101 | $2.76 | 71,246.0000 | 45,602,099 | 7.71% | 0.01% |
| Feb. 18, 2026 | Bhatt Elizabeth | President and COO | M | Stock Option (Right to Buy) | 4000 | $0.00 | 88,911.0000 | 45,602,099 | 4.31% | 0.01% |
| Feb. 18, 2026 | Bhatt Elizabeth | President and COO | M | Common Stock | 4000 | $6.81 | 178,209.0000 | 45,602,099 | 2.30% | 0.01% |
| Feb. 18, 2026 | Bhatt Elizabeth | President and COO | S | Common Stock | 2200 | $28.46 | 176,009.0000 | 45,602,099 | 1.23% | 0.00% |
| Feb. 18, 2026 | Bhatt Elizabeth | President and COO | S | Common Stock | 1800 | $29.58 | 174,209.0000 | 45,602,099 | 1.02% | 0.00% |
| Feb. 6, 2026 | Bhatt Elizabeth | President and COO | A | Stock Option (Right to Buy) | 155000 | $0.00 | 155,000.0000 | 45,602,099 | 9999.99% | 0.34% |
| Feb. 6, 2026 | Labrucherie Gil M | Chief Financial Officer | A | Stock Option (Right to Buy) | 125000 | $0.00 | 125,000.0000 | 45,602,099 | 9999.99% | 0.27% |
| Feb. 6, 2026 | Shaikhly Samira | Chief People Officer | A | Stock Option (Right to Buy) | 80000 | $0.00 | 80,000.0000 | 45,602,099 | 9999.99% | 0.18% |
| Feb. 6, 2026 | Klein Uwe | SVP, Biological Sciences | A | Stock Option (Right to Buy) | 80000 | $0.00 | 80,000.0000 | 45,602,099 | 9999.99% | 0.18% |
| Feb. 6, 2026 | Long Daniel D. | SVP, Drug Discovery | A | Stock Option (Right to Buy) | 80000 | $0.00 | 80,000.0000 | 45,602,099 | 9999.99% | 0.18% |
| Feb. 6, 2026 | Wilson Mark Andrew | Chief Legal Officer | A | Stock Option (Right to Buy) | 165000 | $0.00 | 165,000.0000 | 45,602,099 | 9999.99% | 0.36% |
| Feb. 6, 2026 | Finer Jeffrey | Chief Executive Officer | A | Stock Option (Right to Buy) | 400000 | $0.00 | 400,000.0000 | 45,602,099 | 9999.99% | 0.88% |
| Feb. 6, 2026 | Kim Jae B. | Chief Medical Officer | A | Stock Option (Right to Buy) | 125000 | $0.00 | 125,000.0000 | 45,602,099 | 9999.99% | 0.27% |
| Nov. 10, 2025 | Long Daniel D. | SVP, Drug Discovery | S | Common Stock | 3501 | $18.06 | 92,911.0000 | 45,602,099 | 3.63% | 0.01% |
| Sept. 25, 2025 | Gottesdiener Keith Michael | Not found | A | Stock Option (Right to Buy) | 33246 | $0.00 | 33,246.0000 | 9,891,126 | 9999.99% | 0.34% |
| Aug. 18, 2025 | Klein Uwe | SVP, Biological Sciences | M | Common Stock | 7621 | $6.81 | 127,533.0000 | 9,891,126 | 6.36% | 0.08% |
| Aug. 18, 2025 | Klein Uwe | SVP, Biological Sciences | M | Common Stock | 4935 | $2.76 | 119,912.0000 | 9,891,126 | 4.29% | 0.05% |
| Aug. 18, 2025 | Klein Uwe | SVP, Biological Sciences | M | Stock Option (Right to Buy) | 7621 | $0.00 | 33,027.0000 | 9,891,126 | 18.75% | 0.08% |
| Aug. 18, 2025 | Klein Uwe | SVP, Biological Sciences | M | Common Stock | 10452 | $2.76 | 114,977.0000 | 9,891,126 | 10.00% | 0.11% |
| Aug. 18, 2025 | Klein Uwe | SVP, Biological Sciences | M | Stock Option (Right to Buy) | 4935 | $0.00 | 9,001.0000 | 9,891,126 | 35.41% | 0.05% |
| Aug. 18, 2025 | Klein Uwe | SVP, Biological Sciences | M | Stock Option (Right to Buy) | 10452 | $0.00 | 10,453.0000 | 9,891,126 | 50.00% | 0.11% |
| Aug. 7, 2025 | Labrucherie Gil M | Chief Financial Officer | A | Stock Option (Right to Buy) | 37500 | $0.00 | 37,500.0000 | 9,891,126 | 9999.99% | 0.38% |
| Aug. 7, 2025 | Shaikhly Samira | Chief People Officer | A | Stock Option (Right to Buy) | 30000 | $0.00 | 30,000.0000 | 9,891,126 | 9999.99% | 0.30% |
| Aug. 7, 2025 | Bhatt Elizabeth | President and COO | A | Stock Option (Right to Buy) | 95000 | $0.00 | 95,000.0000 | 9,891,126 | 9999.99% | 0.96% |
| Aug. 7, 2025 | Kim Jae B. | Chief Medical Officer | A | Stock Option (Right to Buy) | 55000 | $0.00 | 55,000.0000 | 9,891,126 | 9999.99% | 0.56% |
| Aug. 7, 2025 | Finer Jeffrey | Chief Executive Officer | A | Stock Option (Right to Buy) | 210000 | $0.00 | 210,000.0000 | 9,891,126 | 9999.99% | 2.12% |
| Aug. 7, 2025 | Long Daniel D. | SVP, Drug Discovery | A | Stock Option (Right to Buy) | 30000 | $0.00 | 30,000.0000 | 9,891,126 | 9999.99% | 0.30% |
| Aug. 7, 2025 | Klein Uwe | SVP, Biological Sciences | A | Stock Option (Right to Buy) | 30000 | $0.00 | 30,000.0000 | 9,891,126 | 9999.99% | 0.30% |
| June 17, 2025 | Ezekowitz Alan | Not found | A | Stock Option (Right to Buy) | 16623 | $0.00 | 16,623.0000 | 9,891,126 | 9999.99% | 0.17% |
| June 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | A | Stock Option (Right to Buy) | 16623 | $0.00 | 16,623.0000 | 9,891,126 | 9999.99% | 0.17% |
| June 17, 2025 | Sharp Shalini | Not found | A | Stock Option (Right to Buy) | 16623 | $0.00 | 16,623.0000 | 9,891,126 | 9999.99% | 0.17% |
| June 17, 2025 | Tong Jeffrey K | Not found | A | Stock Option (Right to Buy) | 16623 | $0.00 | 16,623.0000 | 9,891,126 | 9999.99% | 0.17% |
| June 17, 2025 | Coulie Bernard | Not found | A | Stock Option (Right to Buy) | 16623 | $0.00 | 16,623.0000 | 9,891,126 | 9999.99% | 0.17% |
| June 17, 2025 | Simson Jake | Not found | A | Stock Option (Right to Buy) | 16623 | $0.00 | 16,623.0000 | 9,891,126 | 9999.99% | 0.17% |
| June 17, 2025 | Bassan Abraham | Not found | A | Stock Option (Right to Buy) | 16623 | $0.00 | 16,623.0000 | 9,891,126 | 9999.99% | 0.17% |
| April 3, 2025 | Finer Jeffrey | CEO and President | M | Stock Option (Right to Buy) | 5000 | $0.00 | 397,212.0000 | 9,891,126 | 1.24% | 0.05% |
| April 2, 2025 | Finer Jeffrey | CEO and President | M | Common Stock | 50000 | $2.76 | 821,907.0000 | 9,891,126 | 6.48% | 0.51% |
| April 3, 2025 | Finer Jeffrey | CEO and President | M | Common Stock | 5000 | $2.76 | 826,907.0000 | 9,891,126 | 0.61% | 0.05% |
| April 2, 2025 | Finer Jeffrey | CEO and President | M | Stock Option (Right to Buy) | 50000 | $0.00 | 402,212.0000 | 9,891,126 | 11.06% | 0.51% |
| March 7, 2025 | Ezekowitz Alan | Not found | P | Common Stock | 13319 | $6.93 | 117,420.0000 | 9,891,126 | 12.79% | 0.13% |
| March 5, 2025 | Ezekowitz Alan | Not found | P | Common Stock | 37835 | $5.82 | 62,746.0000 | 9,891,126 | 151.88% | 0.38% |
| March 4, 2025 | Ezekowitz Alan | Not found | P | Common Stock | 7491 | $6.35 | 24,911.0000 | 9,891,126 | 43.00% | 0.08% |
| March 6, 2025 | Ezekowitz Alan | Not found | P | Common Stock | 41355 | $6.00 | 104,101.0000 | 9,891,126 | 65.91% | 0.42% |
| Feb. 27, 2025 | Labrucherie Gil M | Chief Financial Officer | P | Common Stock | 3718 | $5.85 | 40,000.0000 | 9,891,126 | 10.25% | 0.04% |
| Feb. 25, 2025 | Labrucherie Gil M | Chief Financial Officer | P | Common Stock | 6282 | $5.59 | 36,282.0000 | 9,891,126 | 20.94% | 0.06% |
| Feb. 27, 2025 | Finer Jeffrey | CEO and President | P | Common Stock | 3000 | $5.80 | 771,907.0000 | 9,891,126 | 0.39% | 0.03% |
| Feb. 26, 2025 | Finer Jeffrey | CEO and President | P | Common Stock | 4000 | $5.70 | 768,907.0000 | 9,891,126 | 0.52% | 0.04% |
| Feb. 25, 2025 | Finer Jeffrey | CEO and President | P | Common Stock | 10000 | $5.68 | 764,907.0000 | 9,891,126 | 1.32% | 0.10% |
| Feb. 24, 2025 | Third Rock Ventures VI, L.P. | Not found | P | Common Stock | 18861 | $6.00 | 10,427,250.0000 | 9,891,126 | 0.18% | 0.19% |
| Feb. 20, 2025 | Third Rock Ventures VI, L.P. | Not found | P | Common Stock | 612674 | $5.92 | 9,980,721.0000 | 9,891,126 | 6.54% | 6.19% |
| Feb. 21, 2025 | Third Rock Ventures VI, L.P. | Not found | P | Common Stock | 427668 | $5.94 | 10,408,389.0000 | 9,891,126 | 4.28% | 4.32% |
| Feb. 21, 2025 | Labrucherie Gil M | Chief Financial Officer | P | Common Stock | 5000 | $5.85 | 30,000.0000 | 9,891,126 | 20.00% | 0.05% |
| Feb. 20, 2025 | Labrucherie Gil M | Chief Financial Officer | P | Common Stock | 14500 | $5.88 | 25,000.0000 | 9,891,126 | 138.10% | 0.15% |
| Feb. 19, 2025 | Labrucherie Gil M | Chief Financial Officer | P | Common Stock | 10500 | $5.51 | 10,500.0000 | 9,891,126 | 9999.99% | 0.11% |
| Feb. 7, 2025 | Labrucherie Gil M | Chief Financial Officer | A | Stock Option (Right to Buy) | 222000 | $0.00 | 222,000.0000 | 9,891,126 | 9999.99% | 2.24% |
| Oct. 28, 2024 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Common Stock | 1130343 | $0.00 | 1,130,343.0000 | 2,443,678 | 9999.99% | 46.26% |
| Oct. 28, 2024 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Common Stock | 1695515 | $0.00 | 1,695,515.0000 | 2,443,678 | 9999.99% | 69.38% |
| Oct. 28, 2024 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series B Preferred Stock | 9732596 | $0.00 | 0.0000 | 2,443,678 | 100.00% | 100.00% |
| Oct. 28, 2024 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series B Preferred Stock | 14598896 | $0.00 | 0.0000 | 2,443,678 | 100.00% | 100.00% |
| Oct. 28, 2024 | RA CAPITAL MANAGEMENT, L.P. | Not found | P | Common Stock | 341600 | $18.00 | 1,471,943.0000 | 2,443,678 | 30.22% | 13.98% |
| Oct. 28, 2024 | RA CAPITAL MANAGEMENT, L.P. | Not found | P | Common Stock | 3828400 | $18.00 | 5,523,915.0000 | 2,443,678 | 225.80% | 100.00% |
| Oct. 28, 2024 | Third Rock Ventures V, L.P. | Not found | C | Series A Preferred Stock | 41250000 | $0.00 | 0.0000 | 2,443,678 | 100.00% | 100.00% |
| Oct. 28, 2024 | Third Rock Ventures V, L.P. | Not found | C | Common Stock | 4790773 | $0.00 | 8,997,547.0000 | 2,443,678 | 113.88% | 100.00% |
| Oct. 28, 2024 | Third Rock Ventures V, L.P. | Not found | C | Series B Preferred Stock | 24737017 | $0.00 | 0.0000 | 2,443,678 | 100.00% | 100.00% |
| Oct. 28, 2024 | Third Rock Ventures V, L.P. | Not found | P | Common Stock | 370500 | $18.00 | 9,368,047.0000 | 2,443,678 | 4.12% | 15.16% |
| Oct. 28, 2024 | Third Rock Ventures V, L.P. | Not found | P | Common Stock | 279500 | $18.00 | 9,368,047.0000 | 2,443,678 | 3.08% | 11.44% |
| Oct. 28, 2024 | Third Rock Ventures V, L.P. | Not found | C | Common Stock | 2872956 | $0.00 | 9,088,547.0000 | 2,443,678 | 46.22% | 100.00% |