Phillip Frost MD et al, CEO and Chairman, made no open market sales but actively bought shares in three companies over the last 365 days. He purchased OPKO Health Inc (OPK) shares 39 times for a total of $5.2 million, with the latest on November 21, 2025, ranking 165th among 4,983 insiders. Frost also bought NoCopi Technologies Inc (NNUP) once for $215 thousand on June 6, 2025 (1471st rank) and Cocrystal Pharma Inc (COCP) nine times for $220 thousand, most recently February 24, 2026 (1460th rank). These buys exceed the average insider purchase of $1.5 million across 3.3 transactions.
| Transaction Date | Company | Ticker | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Feb. 24, 2026 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 20000 | $1.00 | 1,935,651.0000 | 13,784,065 | 1.04% | 0.15% |
| Feb. 6, 2026 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 50000 | $0.95 | 1,915,651.0000 | 13,784,065 | 2.68% | 0.36% |
| Jan. 9, 2026 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | A | Stock Options (Right to Buy) | 24615 | $0.00 | 24,615.0000 | 13,784,065 | 9999.99% | 0.18% |
| Dec. 31, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 50000 | $0.95 | 1,865,651.0000 | 13,784,065 | 2.75% | 0.36% |
| Dec. 30, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 20000 | $0.97 | 1,815,651.0000 | 13,784,065 | 1.11% | 0.15% |
| Dec. 24, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 25000 | $0.97 | 1,755,651.0000 | 13,784,065 | 1.44% | 0.18% |
| Dec. 26, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 40000 | $0.97 | 1,795,651.0000 | 13,784,065 | 2.28% | 0.29% |
| Nov. 26, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 1500 | $1.00 | 1,728,151.0000 | 13,784,065 | 0.09% | 0.01% |
| Nov. 26, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 2500 | $0.99 | 1,730,651.0000 | 13,784,065 | 0.14% | 0.02% |
| Nov. 25, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 20000 | $0.94 | 1,726,651.0000 | 13,784,065 | 1.17% | 0.15% |
| Nov. 21, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 192870 | $1.34 | 250,402,576.0000 | 779,919,259 | 0.08% | 0.02% |
| Nov. 21, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 191490 | $1.33 | 250,209,706.0000 | 779,919,259 | 0.08% | 0.02% |
| Nov. 21, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 89375 | $1.33 | 250,018,216.0000 | 779,919,259 | 0.04% | 0.01% |
| Nov. 21, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 3894 | $1.32 | 249,928,841.0000 | 779,919,259 | 0.00% | 0.00% |
| Nov. 21, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 102371 | $1.30 | 249,924,947.0000 | 779,919,259 | 0.04% | 0.01% |
| Nov. 20, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 47105 | $1.33 | 249,408,810.0000 | 779,919,259 | 0.02% | 0.01% |
| Nov. 20, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 13664 | $1.35 | 249,822,576.0000 | 779,919,259 | 0.01% | 0.00% |
| Nov. 20, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1757 | $1.35 | 249,808,912.0000 | 779,919,259 | 0.00% | 0.00% |
| Nov. 20, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 24579 | $1.34 | 249,807,155.0000 | 779,919,259 | 0.01% | 0.00% |
| Nov. 20, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 161818 | $1.34 | 249,782,576.0000 | 779,919,259 | 0.06% | 0.02% |
| Nov. 20, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 211948 | $1.33 | 249,620,758.0000 | 779,919,259 | 0.08% | 0.03% |
| Nov. 20, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 119129 | $1.32 | 249,361,705.0000 | 779,919,259 | 0.05% | 0.02% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 12993 | $1.31 | 248,821,672.0000 | 779,919,259 | 0.01% | 0.00% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 36325 | $1.28 | 248,698,901.0000 | 779,919,259 | 0.01% | 0.00% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 58160 | $1.29 | 248,757,061.0000 | 779,919,259 | 0.02% | 0.01% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 300 | $1.29 | 248,757,361.0000 | 779,919,259 | 0.00% | 0.00% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 21236 | $1.30 | 248,778,597.0000 | 779,919,259 | 0.01% | 0.00% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 30082 | $1.30 | 248,808,679.0000 | 779,919,259 | 0.01% | 0.00% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 155496 | $1.32 | 249,242,576.0000 | 779,919,259 | 0.06% | 0.02% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 198904 | $1.32 | 249,087,080.0000 | 779,919,259 | 0.08% | 0.03% |
| Nov. 19, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 66504 | $1.31 | 248,888,176.0000 | 779,919,259 | 0.03% | 0.01% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 410 | $1.25 | 248,082,986.0000 | 779,919,259 | 0.00% | 0.00% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1 | $1.29 | 248,629,004.0000 | 779,919,259 | 0.00% | 0.00% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 83556 | $1.29 | 248,629,003.0000 | 779,919,259 | 0.03% | 0.01% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 428 | $1.28 | 248,545,447.0000 | 779,919,259 | 0.00% | 0.00% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 69728 | $1.28 | 248,545,019.0000 | 779,919,259 | 0.03% | 0.01% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 212608 | $1.28 | 248,475,291.0000 | 779,919,259 | 0.09% | 0.03% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1772 | $1.27 | 248,262,683.0000 | 779,919,259 | 0.00% | 0.00% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 15000 | $1.27 | 248,260,911.0000 | 779,919,259 | 0.01% | 0.00% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | A | Common Stock | 46700 | $1.26 | 248,245,911.0000 | 779,919,259 | 0.02% | 0.01% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 66635 | $1.26 | 248,199,211.0000 | 779,919,259 | 0.03% | 0.01% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 49590 | $1.25 | 248,132,576.0000 | 779,919,259 | 0.02% | 0.01% |
| Nov. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 33572 | $1.29 | 248,662,576.0000 | 779,919,259 | 0.01% | 0.00% |
| Oct. 31, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 150000 | $1.42 | 248,082,576.0000 | 779,919,259 | 0.06% | 0.02% |
| Oct. 28, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | A | Common Stock | 359713 | $1.39 | 1,706,651.0000 | 10,173,790 | 26.71% | 3.54% |
| Oct. 28, 2025 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | A | Warrants | 719426 | $1.39 | 719,426.0000 | 10,173,790 | 9999.99% | 7.07% |
| Sept. 11, 2025 | NOCOPI TECHNOLOGIES INC/MD/ | $NNUP | FROST PHILLIP MD ET AL | TenPercentOwner | A | Common Stock | 21930 | $0.00 | 1,489,712.0000 | 10,792,913 | 1.49% | 0.20% |
| Sept. 4, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | J | Common Stock | 571429 | $0.00 | 6,326,773.0000 | 20,022,836 | 9.93% | 2.85% |
| Sept. 4, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | D | Pre-Funded Warrants | 571429 | $1.75 | 0.0000 | 20,022,836 | 100.00% | 2.85% |
| Sept. 4, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | J | Common Stock | 571429 | $0.00 | 7,302,737.0000 | 20,022,836 | 8.49% | 2.85% |
| Aug. 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Warrants | 571429 | $0.00 | 571,429.0000 | 20,022,836 | 9999.99% | 2.85% |
| Aug. 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Pre-Funded Warrants | 571429 | $1.75 | 571,429.0000 | 20,022,836 | 9999.99% | 2.85% |
| Aug. 18, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | G | Common Stock | 440000 | $0.00 | 247,932,576.0000 | 998,363,636 | 0.18% | 0.04% |
| Aug. 8, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 675000 | $1.32 | 248,372,576.0000 | 998,363,636 | 0.27% | 0.07% |
| June 6, 2025 | NOCOPI TECHNOLOGIES INC/MD/ | $NNUP | FROST PHILLIP MD ET AL | TenPercentOwner | P | Common Stock | 195852 | $1.10 | 1,467,782.0000 | 10,792,913 | 15.40% | 1.81% |
| May 27, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | A | Stock Option (Right to Buy) | 500000 | $0.00 | 500,000.0000 | 998,363,636 | 9999.99% | 0.05% |
| May 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | J | Common Stock | 909297 | $0.00 | 5,755,556.0000 | 20,022,836 | 18.76% | 4.54% |
| May 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Pre-Funded Warrants | 909297 | $2.20 | 909,297.0000 | 20,022,836 | 9999.99% | 4.54% |
| May 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | F | Common Stock | 212 | $2.13 | 5,755,344.0000 | 20,022,836 | 0.00% | 0.00% |
| May 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | D | Pre-Funded Warrants | 909297 | $2.20 | 0.0000 | 20,022,836 | 0.00% | 4.54% |
| May 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Warrants | 909297 | $0.00 | 909,297.0000 | 20,022,836 | 9999.99% | 4.54% |
| April 10, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 125000 | $1.36 | 247,697,576.0000 | 998,363,636 | 0.05% | 0.01% |
| April 8, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 125000 | $1.48 | 247,572,576.0000 | 998,363,636 | 0.05% | 0.01% |
| April 1, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 100000 | $1.65 | 247,447,576.0000 | 998,363,636 | 0.04% | 0.01% |
| March 28, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 150000 | $1.70 | 247,347,576.0000 | 998,363,636 | 0.06% | 0.02% |
| March 20, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | M | Pre-Funded Warrants | 459981 | $2.17 | 459,981.0000 | 20,022,836 | 9999.99% | 2.30% |
| March 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Pre-Funded Warrants | 459981 | $2.17 | 459,981.0000 | 20,022,836 | 9999.99% | 2.30% |
| March 20, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | M | Common Stock | 459981 | $0.00 | 4,846,371.0000 | 20,022,836 | 10.49% | 2.30% |
| March 20, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | F | Common Stock | 112 | $2.04 | 4,846,259.0000 | 20,022,836 | 0.00% | 0.00% |
| March 19, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Pre-Funded Warrants | 459981 | $2.17 | 459,981.0000 | 20,022,836 | 9999.99% | 2.30% |
| March 20, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | F | Common Stock | 112 | $2.04 | 4,837,925.0000 | 20,022,836 | 0.00% | 0.00% |
| March 20, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | M | Common Stock | 459981 | $0.00 | 4,838,037.0000 | 20,022,836 | 10.51% | 2.30% |
| March 20, 2025 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | M | Pre-Funded Warrants | 459981 | $2.17 | 459,981.0000 | 20,022,836 | 9999.99% | 2.30% |
| March 17, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 200000 | $1.74 | 247,197,576.0000 | 998,363,636 | 0.08% | 0.02% |
| March 4, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | 3.75% Convertible Notes due 2029 | 250000 | $436500.00 | 38,558,000.0000 | 998,363,636 | 0.65% | 0.03% |
| March 3, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | 3.75% Convertible Notes due 2029 | 1000000 | $1703250.00 | 37,308,000.0000 | 998,363,636 | 2.75% | 0.10% |
| March 3, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | 3.75% Convertible Notes due 2029 | 1000000 | $1707125.00 | 38,308,000.0000 | 998,363,636 | 2.68% | 0.10% |
| Feb. 28, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 67434 | $1.71 | 246,997,576.0000 | 998,363,636 | 0.03% | 0.01% |
| Feb. 28, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | 3.75% Convertible Notes due 2029 | 1000000 | $1652750.00 | 36,308,000.0000 | 998,363,636 | 2.83% | 0.10% |
| Jan. 28, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 47537 | $1.47 | 246,930,142.0000 | 998,363,636 | 0.02% | 0.00% |
| Jan. 17, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 150000 | $1.47 | 246,882,605.0000 | 998,363,636 | 0.06% | 0.02% |
| Jan. 15, 2025 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500000 | $1.48 | 246,732,605.0000 | 998,363,636 | 0.20% | 0.05% |
| Dec. 13, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 125000 | $1.60 | 246,232,605.0000 | 998,363,636 | 0.05% | 0.01% |
| Dec. 9, 2024 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | X | Common Stock | 647892 | $0.00 | 4,386,390.0000 | 13,660,598 | 17.33% | 4.74% |
| Dec. 11, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500000 | $1.56 | 246,107,605.0000 | 998,363,636 | 0.20% | 0.05% |
| Dec. 9, 2024 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | X | Pre-Funded Warrant | 647892 | $0.00 | 0.0000 | 13,660,598 | 100.00% | 4.74% |
| Dec. 2, 2024 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Pre-Funded Warrant | 647892 | $2.31 | 647,892.0000 | 13,660,598 | 9999.99% | 4.74% |
| Dec. 2, 2024 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | P | Pre-Funded Warrant | 647892 | $2.31 | 647,892.0000 | 13,660,598 | 9999.99% | 4.74% |
| Nov. 29, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 199072 | $1.53 | 245,607,605.0000 | 998,363,636 | 0.08% | 0.02% |
| Nov. 22, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 100000 | $1.59 | 245,408,533.0000 | 998,363,636 | 0.04% | 0.01% |
| Nov. 8, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 280183 | $1.50 | 245,208,533.0000 | 998,363,636 | 0.11% | 0.03% |
| Nov. 14, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 100000 | $1.62 | 245,308,533.0000 | 998,363,636 | 0.04% | 0.01% |
| Nov. 8, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 280183 | $1.50 | 244,708,533.0000 | 998,363,636 | 0.11% | 0.03% |
| Oct. 9, 2024 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | A | Common Stock | 27100 | $0.00 | 1,346,938.0000 | 0 | 2.05% | 0.00% |
| Sept. 11, 2024 | NOCOPI TECHNOLOGIES INC/MD/ | $NNUP | FROST PHILLIP MD ET AL | TenPercentOwner | A | Common Stock | 21930 | $0.00 | 1,271,930.0000 | 10,501,178 | 1.75% | 0.21% |
| Sept. 25, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | 3.75% Convertible Notes due 2029 | 1155000 | $1571050.00 | 33,463,000.0000 | 0 | 3.57% | 0.00% |
| Sept. 27, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | 3.75% Convertible Notes due 2029 | 1845000 | $2541737.50 | 35,308,000.0000 | 0 | 5.51% | 0.00% |
| Sept. 25, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | 3.75% Convertible Notes due 2029 | 1155000 | $1571050.00 | 33,879,050.0000 | 0 | 3.53% | 0.00% |
| Aug. 19, 2024 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Convertible Subordinated Promissory Note | 200000 | $200000.00 | 200,000.0000 | 13,660,598 | 9999.99% | 1.46% |
| July 24, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | A | Common Stock | 500000 | $0.00 | 244,928,350.0000 | 0 | 0.20% | 0.00% |
| July 5, 2024 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | X | Pre-Funded Warrant | 591017 | $0.00 | 0.0000 | 13,660,598 | 100.00% | 4.33% |
| July 5, 2024 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | X | Common Stock | 591017 | $0.00 | 3,738,498.0000 | 13,660,598 | 18.78% | 4.33% |
| May 23, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 99230 | $1.27 | 244,427,580.0000 | 0 | 0.04% | 0.00% |
| May 23, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 770 | $1.27 | 244,428,350.0000 | 0 | 0.00% | 0.00% |
| May 17, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 163997 | $1.29 | 244,328,350.0000 | 0 | 0.07% | 0.00% |
| May 13, 2024 | Fluent, Inc. | $FLNT | FROST PHILLIP MD ET AL | TenPercentOwner | A | Pre-Funded Warrant | 591017 | $3.38 | 591,017.0000 | 13,660,598 | 9999.99% | 4.33% |
| March 18, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500000 | $0.87 | 244,164,353.0000 | 0 | 0.21% | 0.00% |
| March 14, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500000 | $0.89 | 243,664,353.0000 | 0 | 0.21% | 0.00% |
| March 13, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500000 | $0.93 | 243,164,353.0000 | 0 | 0.21% | 0.00% |
| March 12, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 600000 | $0.93 | 242,664,353.0000 | 0 | 0.25% | 0.00% |
| Feb. 28, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500000 | $0.99 | 242,064,353.0000 | 0 | 0.21% | 0.00% |
| Feb. 21, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1000000 | $0.99 | 241,564,353.0000 | 0 | 0.42% | 0.00% |
| Feb. 7, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1500000 | $0.98 | 240,564,353.0000 | 0 | 0.63% | 0.00% |
| Jan. 19, 2024 | BioCardia, Inc. | $BCDA | FROST PHILLIP MD ET AL | TenPercentOwner | S | Common Stock | 129802 | $0.43 | 1,896,025.0000 | 0 | 6.41% | 0.00% |
| Jan. 19, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500000 | $0.98 | 239,064,353.0000 | 0 | 0.21% | 0.00% |
| Jan. 18, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 400000 | $0.97 | 238,564,353.0000 | 0 | 0.17% | 0.00% |
| Jan. 16, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1000000 | $0.95 | 238,164,353.0000 | 0 | 0.42% | 0.00% |
| Jan. 11, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 511531 | $0.94 | 237,164,353.0000 | 0 | 0.22% | 0.00% |
| Jan. 5, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1500000 | $0.90 | 236,652,822.0000 | 0 | 0.64% | 0.00% |
| Jan. 4, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | D | 5% Convertible Notes due 2025 | 25000000 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Jan. 4, 2024 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | A | 3.75% Convertible Notes due 2029 | 32308000 | $0.00 | 32,308,000.0000 | 0 | 9999.99% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 149763 | $1.28 | 234,462,822.0000 | 0 | 0.06% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 10101 | $1.27 | 234,162,923.0000 | 0 | 0.00% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 56199 | $1.27 | 234,219,122.0000 | 0 | 0.02% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 618 | $1.27 | 234,219,740.0000 | 0 | 0.00% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 93319 | $1.28 | 234,313,059.0000 | 0 | 0.04% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 12273 | $1.29 | 234,475,095.0000 | 0 | 0.01% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 62480 | $1.29 | 234,537,575.0000 | 0 | 0.03% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 67147 | $1.30 | 234,604,722.0000 | 0 | 0.03% | 0.00% |
| Nov. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 48100 | $1.30 | 234,652,822.0000 | 0 | 0.02% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1900 | $1.22 | 234,654,722.0000 | 0 | 0.00% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 87776 | $1.23 | 234,742,498.0000 | 0 | 0.04% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 50000 | $1.24 | 234,792,498.0000 | 0 | 0.02% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 5324 | $1.24 | 234,797,822.0000 | 0 | 0.00% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 19072 | $1.25 | 234,816,894.0000 | 0 | 0.01% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 49481 | $1.25 | 234,866,375.0000 | 0 | 0.02% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500 | $1.25 | 234,866,875.0000 | 0 | 0.00% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 39202 | $1.26 | 234,906,077.0000 | 0 | 0.02% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 138871 | $1.26 | 235,044,948.0000 | 0 | 0.06% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 400 | $1.26 | 235,045,348.0000 | 0 | 0.00% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 24300 | $1.27 | 235,069,648.0000 | 0 | 0.01% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 4500 | $1.27 | 235,074,148.0000 | 0 | 0.00% | 0.00% |
| Nov. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 78674 | $1.27 | 235,152,822.0000 | 0 | 0.03% | 0.00% |
| Aug. 17, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 23264 | $1.76 | 234,131,854.0000 | 0 | 0.01% | 0.00% |
| Aug. 17, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 6168 | $1.77 | 234,138,022.0000 | 0 | 0.00% | 0.00% |
| Aug. 17, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 14800 | $1.78 | 234,152,822.0000 | 0 | 0.01% | 0.00% |
| Aug. 17, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1500 | $1.74 | 234,054,322.0000 | 0 | 0.00% | 0.00% |
| Aug. 17, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1450 | $1.75 | 234,055,772.0000 | 0 | 0.00% | 0.00% |
| Aug. 17, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 47050 | $1.75 | 234,102,822.0000 | 0 | 0.02% | 0.00% |
| Aug. 17, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 3918 | $1.76 | 234,106,740.0000 | 0 | 0.00% | 0.00% |
| Aug. 17, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1850 | $1.76 | 234,108,590.0000 | 0 | 0.00% | 0.00% |
| Aug. 14, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 57358 | $1.75 | 234,044,999.0000 | 0 | 0.02% | 0.00% |
| Aug. 14, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 3900 | $1.76 | 234,048,899.0000 | 0 | 0.00% | 0.00% |
| Aug. 14, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 3923 | $1.76 | 234,052,822.0000 | 0 | 0.00% | 0.00% |
| Aug. 14, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 9819 | $1.75 | 233,987,641.0000 | 0 | 0.00% | 0.00% |
| Aug. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 13811 | $1.83 | 233,977,822.0000 | 0 | 0.01% | 0.00% |
| Aug. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 20843 | $1.81 | 233,904,070.0000 | 0 | 0.01% | 0.00% |
| Aug. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 5405 | $1.81 | 233,883,227.0000 | 0 | 0.00% | 0.00% |
| Aug. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 25752 | $1.82 | 233,929,822.0000 | 0 | 0.01% | 0.00% |
| Aug. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 27800 | $1.82 | 233,957,622.0000 | 0 | 0.01% | 0.00% |
| Aug. 9, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 6389 | $1.83 | 233,964,011.0000 | 0 | 0.00% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 3400 | $1.82 | 233,275,207.0000 | 0 | 0.00% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 54271 | $1.83 | 233,329,478.0000 | 0 | 0.02% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 4530 | $1.83 | 233,334,008.0000 | 0 | 0.00% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 177580 | $1.83 | 233,511,588.0000 | 0 | 0.08% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 500 | $1.83 | 233,512,088.0000 | 0 | 0.00% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 33564 | $1.84 | 233,545,652.0000 | 0 | 0.01% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 70000 | $1.84 | 233,615,652.0000 | 0 | 0.03% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 100 | $1.84 | 233,615,752.0000 | 0 | 0.00% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 45527 | $1.85 | 233,661,279.0000 | 0 | 0.02% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 9100 | $1.85 | 233,670,379.0000 | 0 | 0.00% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 160243 | $1.85 | 233,830,622.0000 | 0 | 0.07% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 21432 | $1.86 | 233,852,054.0000 | 0 | 0.01% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 25768 | $1.86 | 233,877,822.0000 | 0 | 0.01% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 43885 | $1.82 | 233,271,807.0000 | 0 | 0.02% | 0.00% |
| Aug. 7, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 100 | $1.82 | 233,227,922.0000 | 0 | 0.00% | 0.00% |
| July 18, 2023 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | A | Stock Options (Right to Buy) | 19333 | $0.00 | 19,333.0000 | 0 | 9999.99% | 0.00% |
| May 18, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | A | Stock Option (Right to Buy) | 800000 | $0.00 | 800,000.0000 | 0 | 9999.99% | 0.00% |
| April 4, 2023 | Cocrystal Pharma, Inc. | $COCP | FROST PHILLIP MD ET AL | Director | P | Common Stock | 1015229 | $1.97 | 1,319,838.0000 | 0 | 333.29% | 0.00% |
| March 22, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 352 | $1.33 | 233,227,822.0000 | 0 | 0.00% | 0.00% |
| March 22, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 57100 | $1.32 | 233,085,622.0000 | 0 | 0.02% | 0.00% |
| March 22, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 116648 | $1.33 | 233,227,470.0000 | 0 | 0.05% | 0.00% |
| March 22, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 25200 | $1.32 | 233,110,822.0000 | 0 | 0.01% | 0.00% |
| March 22, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 700 | $1.31 | 233,028,522.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 6037 | $1.28 | 233,007,822.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 20000 | $1.29 | 233,027,822.0000 | 0 | 0.01% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 20700 | $1.16 | 232,727,822.0000 | 0 | 0.01% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 59117 | $1.16 | 232,707,122.0000 | 0 | 0.03% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1000 | $1.15 | 232,648,005.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 81336 | $1.15 | 232,647,005.0000 | 0 | 0.03% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1900 | $1.15 | 232,565,669.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 13569 | $1.15 | 232,563,769.0000 | 0 | 0.01% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 348101 | $1.14 | 232,550,200.0000 | 0 | 0.15% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 107200 | $1.14 | 232,202,099.0000 | 0 | 0.05% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 5700 | $1.13 | 232,094,899.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 22049 | $1.13 | 232,089,199.0000 | 0 | 0.01% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 39028 | $1.13 | 232,067,150.0000 | 0 | 0.02% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 300 | $1.12 | 232,028,122.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 15386 | $1.23 | 232,751,166.0000 | 0 | 0.01% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 11556 | $1.24 | 232,763,922.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 11300 | $1.25 | 232,775,222.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 92000 | $1.25 | 232,867,222.0000 | 0 | 0.04% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 89710 | $1.26 | 232,956,932.0000 | 0 | 0.04% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 2700 | $1.26 | 232,959,632.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 7341 | $1.27 | 232,966,973.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 34812 | $1.27 | 233,001,785.0000 | 0 | 0.01% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 7958 | $1.23 | 232,735,780.0000 | 0 | 0.00% | 0.00% |
| March 8, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | P | Common Stock | 1200 | $1.24 | 232,752,366.0000 | 0 | 0.00% | 0.00% |
| Feb. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | A | 5% Convertible Promissory Notes due 2025 | 25000000 | $25000000.00 | 25,000,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2023 | OPKO HEALTH, INC. | $OPK | FROST PHILLIP MD ET AL | CEO & Chairman | D | 5% Convertible Promissory Notes due 2023 | 25000000 | $25000000.00 | 0.0000 | 0 | 100.00% | 0.00% |