SEC Insider Transactions from Zanganeh Mahkam.

Last updated: 2026-03-16 13:03 UTC | Total transactions: 47

Zanganeh Mahkam, Co-Chief Executive Officer of Summit Therapeutics Inc. ($SMMT), made three open market purchases totaling $6.5 million in the last 365 days, with the most recent on October 21, 2025. This insider buying ranks 141st among nearly 5,000 individuals in our database, surpassing the average purchase amount of $1.5 million and average of 3.3 transactions. Mahkam reported no open market sales during this period.

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Transaction Date Company Ticker Insider Name Title Transaction Type Security Shares Price Shares Owned Following Total Shares Outstanding % of Owned % of Outstanding
Jan. 2, 2026 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer A Stock Option (right to buy) 11232 $8.76 11,232.0000 744,442,538 9999.99% 0.00%
Oct. 21, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer A Common Stock 266808 $18.74 606,105,809.0000 744,442,538 0.04% 0.04%
Oct. 21, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer P Common Stock 26680 $18.74 606,105,809.0000 744,442,538 0.00% 0.00%
Oct. 21, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer A Common Stock 13980789 $18.74 606,105,809.0000 744,442,538 2.36% 1.88%
Sept. 10, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer P Common Stock 333394 $17.68 591,826,532.0000 737,679,704 0.06% 0.05%
Sept. 11, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer P Common Stock 5000 $18.07 591,831,532.0000 737,679,704 0.00% 0.00%
Aug. 15, 2025 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director A Stock Option (right to buy) 24134 $0.00 24,134.0000 67,273,800 9999.99% 0.04%
Aug. 15, 2025 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director A Stock Option (right to buy) 30000 $0.00 30,000.0000 67,273,800 9999.99% 0.04%
May 30, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer M Common Stock 74545 $2.64 591,493,138.0000 737,679,704 0.01% 0.01%
May 30, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer M Stock Option (right to buy) 74545 $0.00 0.0000 737,679,704 100.00% 0.01%
April 29, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer A Stock Option (right to buy) 400000 $0.00 400,000.0000 737,679,704 9999.99% 0.05%
April 29, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer A Stock Option (right to buy) 1040000 $0.00 1,040,000.0000 737,679,704 9999.99% 0.14%
April 29, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer A Stock Option (right to buy) 9590558 $0.00 9,590,558.0000 737,679,704 9999.99% 1.30%
April 8, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer X Common Stock 3985055 $1.58 591,418,593.0000 737,679,704 0.68% 0.54%
April 8, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer X Warrant (right to buy) 3985055 $0.00 0.0000 737,679,704 0.00% 0.54%
Feb. 3, 2025 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director X Warrant (right to buy) 30121 $0.00 0.0000 0 100.00% 0.00%
Jan. 24, 2025 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director X Common Stock 30121 $11.00 843,348.0000 0 3.70% 0.00%
Feb. 3, 2025 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director X Common Stock 30121 $11.00 873,469.0000 0 3.57% 0.00%
Jan. 24, 2025 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director X Warrant (right to buy) 30121 $0.00 0.0000 0 100.00% 0.00%
Jan. 2, 2025 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer A Stock Option (right to buy) 10724 $9.18 85,269.0000 0 14.39% 0.00%
Oct. 3, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer X Common Stock 315681 $1.58 35,738,442.0000 0 0.89% 0.00%
Oct. 3, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer X Warrant (right to buy) 315681 $0.00 0.0000 0 100.00% 0.00%
Sept. 11, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer A Common Stock 44052 $22.70 35,422,761.0000 0 0.12% 0.00%
Aug. 23, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer A Performance Stock Option (right to buy) 260000 $0.00 260,000.0000 0 9999.99% 0.00%
Aug. 23, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer A Performance Stock Option (right to buy) 2397640 $0.00 2,397,640.0000 0 9999.99% 0.00%
Aug. 23, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer A Performance Stock Option (right to buy) 100000 $0.00 100,000.0000 0 9999.99% 0.00%
Aug. 9, 2024 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director A Stock Option (right to buy) 200000 $0.00 200,000.0000 0 9999.99% 0.00%
July 3, 2024 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director P Warrant (right to buy) 30121 $0.00 30,121.0000 0 9999.99% 0.00%
July 3, 2024 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director P Warrant (right to buy) 30121 $0.00 30,121.0000 0 9999.99% 0.00%
July 3, 2024 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director X Common Stock 60242 $0.00 813,227.0000 0 8.00% 0.00%
June 6, 2024 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director A Stock Option (right to buy) 20000 $0.00 20,000.0000 0 9999.99% 0.00%
June 6, 2024 PULSE BIOSCIENCES, INC. $PLSE Zanganeh Mahkam Director A Stock Option (right to buy) 8247 $0.00 8,247.0000 0 9999.99% 0.00%
March 27, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer P Common Stock 34321 $3.72 25,494,614.0000 0 0.13% 0.00%
March 26, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer P Common Stock 30000 $3.75 25,474,614.0000 0 0.12% 0.00%
March 27, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer P Common Stock 20000 $3.71 25,494,614.0000 0 0.08% 0.00%
March 27, 2024 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer P Common Stock 26000 $3.72 25,494,614.0000 0 0.10% 0.00%
Dec. 12, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer P Common Stock 5000 $2.07 25,384,293.0000 0 0.02% 0.00%
Dec. 11, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer X Common Stock 315681 $1.58 25,384,293.0000 0 1.26% 0.00%
Dec. 11, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer X Warrant (right to buy) 489814 $0.00 0.0000 0 100.00% 0.00%
Dec. 11, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer X Warrant (right to buy) 315681 $0.00 0.0000 0 100.00% 0.00%
Dec. 11, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer X Common Stock 489814 $1.44 25,379,293.0000 0 1.97% 0.00%
Oct. 13, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Chief Executive Officer A Stock Option (right to buy) 11988198 $0.00 11,988,198.0000 0 9999.99% 0.00%
March 8, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-CEO & President P Common Stock 16778415 $1.05 34,457,893.0000 0 94.90% 0.00%
March 8, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-CEO & President P Common Stock 6748629 $1.05 34,457,893.0000 0 24.36% 0.00%
March 8, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer P Common Stock 15973743 $1.05 34,457,893.0000 0 86.42% 0.00%
March 8, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer P Common Stock 6748629 $1.05 34,457,893.0000 0 24.36% 0.00%
March 8, 2023 Summit Therapeutics Inc. $SMMT Zanganeh Mahkam Co-Chief Executive Officer P Common Stock 804672 $1.05 34,457,893.0000 0 2.39% 0.00%