SEC Insider Transactions from EcoR1 Capital, LLC.

Last updated: 2026-03-16 13:02 UTC | Total transactions: 82

EcoR1 Capital, LLC has filed 82 insider transactions across 9 companies since January 2023.

Most recent transaction: a transaction of 128506 shares of Aktis Oncology, Inc. ($AKTS) on January 12, 2026.

Activity breakdown: 55 open-market purchases and 12 sales.

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Transaction Date Company Ticker Insider Name Title Transaction Type Security Shares Price Shares Owned Following Total Shares Outstanding % of Owned % of Outstanding
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Common Stock 128506 $0.00 128,506.0000 0 9999.99% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Common Stock 202862 $0.00 202,862.0000 0 9999.99% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Common Stock 2270879 $0.00 2,270,879.0000 0 9999.99% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Class A Common Stock 965190 $0.00 1,051,412.0000 0 1119.42% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Series B Redeemable Convertible Preferred Stock 102500 $0.00 0.0000 0 100.00% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Series B Redeemable Convertible Preferred Stock 2397500 $0.00 0.0000 0 100.00% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Series A Redeemable Convertible Preferred Stock 488891 $0.00 0.0000 0 100.00% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Class A Common Stock 86222 $0.00 1,051,412.0000 0 8.93% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Series A Redeemable Convertible Preferred Stock 997299 $0.00 0.0000 0 100.00% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director C Series A Redeemable Convertible Preferred Stock 9913810 $0.00 0.0000 0 100.00% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director P Common Stock 144443 $18.00 347,305.0000 0 71.20% 0.00%
Jan. 12, 2026 Aktis Oncology, Inc. $AKTS EcoR1 Capital, LLC Director P Common Stock 2077779 $18.00 4,348,658.0000 0 91.50% 0.00%
July 29, 2025 Adaptimmune Therapeutics PLC $ADAPY EcoR1 Capital, LLC TenPercentOwner S Ordinary Shares 2687460 $0.10 127,805,220.0000 1,584,522,868 2.06% 0.17%
July 28, 2025 Adaptimmune Therapeutics PLC $ADAPY EcoR1 Capital, LLC TenPercentOwner S Ordinary Shares 33931740 $0.11 130,492,680.0000 1,584,522,868 20.64% 2.14%
July 30, 2025 Adaptimmune Therapeutics PLC $ADAPY EcoR1 Capital, LLC TenPercentOwner S Ordinary Shares 27433338 $0.10 100,371,882.0000 1,584,522,868 21.46% 1.73%
June 26, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director F Common Stock 41 $12.71 22,970,388.0000 75,878,738 0.00% 0.00%
June 26, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director X Pre-Funded Warrants (right to acquire) 5086521 $0.00 0.0000 75,878,738 100.00% 6.70%
June 26, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director X Common Stock 5086480 $0.00 22,970,388.0000 75,878,738 28.44% 6.70%
May 15, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 49502 $11.43 17,877,989.0000 75,878,738 0.28% 0.07%
May 19, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 5919 $11.78 17,883,908.0000 75,878,738 0.03% 0.01%
May 14, 2025 iTeos Therapeutics, Inc. $ITOS EcoR1 Capital, LLC TenPercentOwner P Common Stock 1658978 $7.41 7,388,978.0000 38,194,341 28.95% 4.34%
May 15, 2025 iTeos Therapeutics, Inc. $ITOS EcoR1 Capital, LLC TenPercentOwner P Common Stock 3300000 $8.00 10,688,978.0000 38,194,341 44.66% 8.64%
May 5, 2025 PROTHENA CORP PUBLIC LTD CO $PRTA EcoR1 Capital, LLC TenPercentOwner S Ordinary Shares 977693 $8.11 7,288,649.0000 53,772,000 11.83% 1.82%
May 2, 2025 PROTHENA CORP PUBLIC LTD CO $PRTA EcoR1 Capital, LLC TenPercentOwner S Ordinary Shares 3317938 $8.36 8,266,342.0000 53,772,000 28.64% 6.17%
May 6, 2025 PROTHENA CORP PUBLIC LTD CO $PRTA EcoR1 Capital, LLC TenPercentOwner S Ordinary Shares 1984053 $7.64 5,304,596.0000 53,772,000 27.22% 3.69%
April 16, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 73953 $11.16 17,773,727.0000 75,878,738 0.42% 0.10%
April 17, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 54760 $11.52 17,828,487.0000 75,878,738 0.31% 0.07%
April 4, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 196438 $11.17 17,699,774.0000 75,878,738 1.12% 0.26%
April 3, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 120770 $11.84 17,503,336.0000 75,878,738 0.69% 0.16%
April 1, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 48658 $11.60 17,308,206.0000 75,878,738 0.28% 0.06%
March 31, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 4397 $11.75 17,259,548.0000 75,878,738 0.03% 0.01%
April 2, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 74360 $11.85 17,382,566.0000 75,878,738 0.43% 0.10%
March 25, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 53501 $12.91 17,211,303.0000 75,878,738 0.31% 0.07%
March 26, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 43848 $12.24 17,255,151.0000 75,878,738 0.25% 0.06%
March 20, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 73476 $12.93 17,104,080.0000 75,878,738 0.43% 0.10%
March 24, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 22689 $13.08 17,157,802.0000 75,878,738 0.13% 0.03%
March 21, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 31033 $12.78 17,135,113.0000 75,878,738 0.18% 0.04%
March 18, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 113880 $12.65 16,972,298.0000 75,878,738 0.68% 0.15%
March 19, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 58306 $12.64 17,030,604.0000 75,878,738 0.34% 0.08%
March 17, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 56277 $12.23 16,858,418.0000 75,878,738 0.33% 0.07%
March 12, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 292934 $12.25 16,333,785.0000 75,878,738 1.83% 0.39%
March 13, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 468356 $12.48 16,802,141.0000 75,878,738 2.87% 0.62%
March 11, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 320690 $11.49 16,040,851.0000 75,878,738 2.04% 0.42%
Jan. 16, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 121681 $13.89 15,700,413.0000 75,878,738 0.78% 0.16%
Jan. 17, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 19748 $13.87 15,720,161.0000 75,878,738 0.13% 0.03%
Jan. 15, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 39029 $14.01 15,578,732.0000 75,878,738 0.25% 0.05%
Jan. 13, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 74125 $13.39 15,485,203.0000 75,878,738 0.48% 0.10%
Jan. 14, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 54500 $13.56 15,539,703.0000 75,878,738 0.35% 0.07%
Jan. 8, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 21021 $14.07 15,206,980.0000 75,878,738 0.14% 0.03%
Jan. 10, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 204098 $13.13 15,411,078.0000 75,878,738 1.34% 0.27%
Jan. 2, 2025 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 157880 $14.78 15,185,959.0000 75,878,738 1.05% 0.21%
Dec. 30, 2024 ANAPTYSBIO, INC $ANAB EcoR1 Capital, LLC Director P Common Stock 65184 $12.92 7,860,180.0000 0 0.84% 0.00%
Dec. 31, 2024 ANAPTYSBIO, INC $ANAB EcoR1 Capital, LLC Director P Common Stock 13268 $12.93 7,873,448.0000 0 0.17% 0.00%
Jan. 2, 2025 ANAPTYSBIO, INC $ANAB EcoR1 Capital, LLC Director P Common Stock 6646 $12.95 7,880,094.0000 0 0.08% 0.00%
Dec. 30, 2024 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 58988 $14.47 14,881,578.0000 76,266,177 0.40% 0.08%
Dec. 31, 2024 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 146501 $14.57 15,028,079.0000 76,266,177 0.98% 0.19%
Dec. 24, 2024 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 11958 $14.12 14,704,239.0000 76,266,177 0.08% 0.02%
Dec. 26, 2024 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 16692 $14.38 14,720,931.0000 76,266,177 0.11% 0.02%
Dec. 27, 2024 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 101659 $14.49 14,822,590.0000 76,266,177 0.69% 0.13%
Dec. 23, 2024 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 251502 $14.25 14,692,281.0000 76,266,177 1.74% 0.33%
Dec. 20, 2024 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 704488 $14.08 14,440,779.0000 76,266,177 5.13% 0.92%
Dec. 19, 2024 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Director P Common Stock 298818 $13.53 13,736,291.0000 76,266,177 2.22% 0.39%
Dec. 26, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Pre-Funded Warrants 5086521 $9.83 5,086,521.0000 65,249,184 9999.99% 7.80%
Dec. 19, 2024 Mersana Therapeutics, Inc. $MRSN EcoR1 Capital, LLC TenPercentOwner J Common Stock 8036688 $0.00 11,328,000.0000 0 41.50% 0.00%
Dec. 19, 2024 Mersana Therapeutics, Inc. $MRSN EcoR1 Capital, LLC TenPercentOwner J Pre-Funded Warrants 8036688 $0.00 8,036,688.0000 0 9999.99% 0.00%
Nov. 7, 2024 Tango Therapeutics, Inc. $TNGX EcoR1 Capital, LLC TenPercentOwner S Common Stock 62318 $3.29 11,773,860.0000 0 0.53% 0.00%
Nov. 6, 2024 Tango Therapeutics, Inc. $TNGX EcoR1 Capital, LLC TenPercentOwner S Common Stock 1494558 $3.28 11,836,178.0000 0 11.21% 0.00%
Nov. 7, 2024 Tango Therapeutics, Inc. $TNGX EcoR1 Capital, LLC TenPercentOwner S Common Stock 1143124 $2.92 10,630,736.0000 0 9.71% 0.00%
Aug. 14, 2024 ANAPTYSBIO, INC $ANAB EcoR1 Capital, LLC TenPercentOwner P Common Stock 273972 $36.50 7,794,996.0000 0 3.64% 0.00%
Dec. 26, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Pre-Funded Warrants 5086521 $9.83 5,086,521.0000 65,249,184 9999.99% 7.80%
June 16, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Common Stock 3350000 $8.12 13,437,473.0000 65,249,184 33.21% 5.13%
March 28, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC Not found P Common Stock 200000 $8.00 10,087,473.0000 65,249,184 2.02% 0.31%
Jan. 19, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Common Stock 144100 $9.49 9,724,073.0000 65,249,184 1.50% 0.22%
Jan. 20, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Common Stock 163400 $9.88 9,887,473.0000 65,249,184 1.68% 0.25%
Jan. 18, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Common Stock 203000 $10.00 9,579,973.0000 65,249,184 2.16% 0.31%
Jan. 13, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Common Stock 342100 $9.81 8,936,973.0000 65,249,184 3.98% 0.52%
Jan. 17, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Common Stock 440000 $9.80 9,376,973.0000 65,249,184 4.92% 0.67%
Jan. 11, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Common Stock 106300 $7.87 8,594,873.0000 65,249,184 1.25% 0.16%
Jan. 10, 2023 Zymeworks Inc. $ZYME EcoR1 Capital, LLC TenPercentOwner P Common Stock 920000 $7.65 8,488,573.0000 65,249,184 12.16% 1.41%
Jan. 9, 2023 Voyager Therapeutics, Inc. $VYGR EcoR1 Capital, LLC TenPercentOwner S Common Stock 456000 $7.67 4,297,907.0000 38,356,810 9.59% 1.19%
Jan. 11, 2023 Voyager Therapeutics, Inc. $VYGR EcoR1 Capital, LLC TenPercentOwner S Common Stock 110000 $8.50 3,851,507.0000 38,356,810 2.78% 0.29%
Jan. 10, 2023 Voyager Therapeutics, Inc. $VYGR EcoR1 Capital, LLC TenPercentOwner S Common Stock 336400 $8.05 3,961,507.0000 38,356,810 7.83% 0.88%