Lori Macomber, EVP, CFO and Treasurer of Karyopharm Therapeutics Inc. ($KPTI), made one open market sale of common shares in the last year, totaling $10,244. Her most recent sale occurred on February 3, 2026. Among 11,678 insiders with sales, her activity ranks 11,271st by amount, well below the average of $8.6 million across about 6.4 transactions. She reported no open market purchases.
| Transaction Date | Company | Ticker | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Feb. 3, 2026 | Karyopharm Therapeutics Inc. | $KPTI | Macomber Lori | EVP, CFO & Treasurer | S | Common Stock | 1626 | $6.30 | 85,105.0000 | 17,050,876,000 | 1.87% | 0.00% |
| Jan. 31, 2026 | Karyopharm Therapeutics Inc. | $KPTI | Macomber Lori | EVP, CFO & Treasurer | A | Common Stock | 32415 | $0.00 | 86,731.0000 | 17,050,876,000 | 59.68% | 0.00% |
| Oct. 15, 2025 | Karyopharm Therapeutics Inc. | $KPTI | Macomber Lori | EVP, CFO & Treasurer | A | Common Stock | 43650 | $0.00 | 54,316.0000 | 126,240,054 | 409.24% | 0.03% |
| Jan. 31, 2025 | Karyopharm Therapeutics Inc. | $KPTI | Macomber Lori | EVP, CFO & Treasurer | A | Common Stock | 160000 | $0.00 | 160,000.0000 | 0 | 9999.99% | 0.00% |
| Jan. 31, 2025 | Karyopharm Therapeutics Inc. | $KPTI | Macomber Lori | EVP, CFO & Treasurer | A | Stock Option (right to buy) | 650000 | $0.00 | 650,000.0000 | 0 | 9999.99% | 0.00% |