In the last 12 months, insiders at Disc Medicine, Inc. ($IRON) filed 531 transactions with the SEC: 15 open-market purchases totaling $29,000,150 and 313 sales totaling $368,020,204. Net insider sentiment: net selling.
Disc Medicine, Inc. operates in the Pharmaceutical preparations industry (Life sciences sector).
Most Active Insiders
- AI DMI LLC (Not found) — 2 transactions totaling $74,873,474
- Atlas Venture Fund X, L.P. (TenPercentOwner) — 37 transactions totaling $62,869,014
- Ashiya Mona (Director) — 49 transactions totaling $58,262,106
- ORBIMED ADVISORS LLC (Director) — 51 transactions totaling $58,262,106
- Novo Holdings A/S (TenPercentOwner) — 1 transaction totaling $57,625,000
View all SEC Filings for Disc Medicine, Inc. (IRON).
Set Up your own filters →Recent Insider Transactions
| Transaction Date | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|
| March 2, 2026 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 4392 | $65.52 | 88,197.0000 | 37,750,162 | 4.74% | 0.01% |
| March 2, 2026 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 2986 | $66.41 | 85,211.0000 | 37,750,162 | 3.39% | 0.01% |
| Feb. 25, 2026 | Franchi Jean M. | Chief Financial Officer | S | Common Stock | 353 | $69.06 | 70,990.0000 | 37,750,162 | 0.49% | 0.00% |
| Feb. 17, 2026 | Franchi Jean M. | Chief Financial Officer | S | Common Stock | 4075 | $62.86 | 78,424.0000 | 37,750,162 | 4.94% | 0.01% |
| Feb. 18, 2026 | Franchi Jean M. | Chief Financial Officer | S | Common Stock | 3397 | $65.01 | 75,027.0000 | 37,750,162 | 4.33% | 0.01% |
| Feb. 18, 2026 | Franchi Jean M. | Chief Financial Officer | S | Common Stock | 3684 | $65.89 | 71,343.0000 | 37,750,162 | 4.91% | 0.01% |
| Feb. 17, 2026 | Khara Rahul | Chief Legal Officer | S | Common Stock | 2853 | $62.86 | 52,173.0000 | 37,750,162 | 5.18% | 0.01% |
| Feb. 17, 2026 | Stephenson Pamela | Chief Commercial Officer | S | Common Stock | 5531 | $62.86 | 80,998.0000 | 37,750,162 | 6.39% | 0.01% |
| Feb. 17, 2026 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 3256 | $62.86 | 92,589.0000 | 37,750,162 | 3.40% | 0.01% |
| Feb. 17, 2026 | Yu Jonathan Yen-Wen | Chief Operating Officer | S | Common Stock | 3231 | $62.86 | 54,324.0000 | 37,750,162 | 5.61% | 0.01% |
| Feb. 17, 2026 | Quisel John D | Chief Executive Officer | S | Common Stock | 13264 | $62.86 | 226,064.0000 | 37,750,162 | 5.54% | 0.04% |
| Feb. 10, 2026 | Stephenson Pamela | Chief Commercial Officer | A | Stock Option (Right to Buy) | 25500 | $0.00 | 25,500.0000 | 37,750,162 | 9999.99% | 0.07% |
| Feb. 10, 2026 | Khara Rahul | Chief Legal Officer | A | Common Stock | 17000 | $0.00 | 55,026.0000 | 37,750,162 | 44.71% | 0.05% |
| Feb. 10, 2026 | Quisel John D | Chief Executive Officer | A | Stock Option (Right to Buy) | 82800 | $0.00 | 82,800.0000 | 37,750,162 | 9999.99% | 0.22% |
| Feb. 10, 2026 | Quisel John D | Chief Executive Officer | A | Common Stock | 55200 | $0.00 | 239,328.0000 | 37,750,162 | 29.98% | 0.15% |
| Feb. 10, 2026 | Franchi Jean M. | Chief Financial Officer | A | Stock Option (Right to Buy) | 25500 | $0.00 | 25,500.0000 | 37,750,162 | 9999.99% | 0.07% |
| Feb. 10, 2026 | Franchi Jean M. | Chief Financial Officer | A | Common Stock | 19000 | $0.00 | 82,499.0000 | 37,750,162 | 29.92% | 0.05% |
| Feb. 10, 2026 | Yu Jonathan Yen-Wen | Chief Operating Officer | A | Stock Option (Right to Buy) | 25500 | $0.00 | 25,500.0000 | 37,750,162 | 9999.99% | 0.07% |
| Feb. 10, 2026 | Yu Jonathan Yen-Wen | Chief Operating Officer | A | Common Stock | 17000 | $0.00 | 57,555.0000 | 37,750,162 | 41.92% | 0.05% |
| Feb. 10, 2026 | Savage William Jacob | Chief Medical Officer | A | Stock Option (Right to Buy) | 25500 | $0.00 | 25,500.0000 | 37,750,162 | 9999.99% | 0.07% |
| Feb. 10, 2026 | Savage William Jacob | Chief Medical Officer | A | Common Stock | 17000 | $0.00 | 95,845.0000 | 37,750,162 | 21.56% | 0.05% |
| Feb. 10, 2026 | Khara Rahul | Chief Legal Officer | A | Stock Option (Right to Buy) | 25500 | $0.00 | 25,500.0000 | 37,750,162 | 9999.99% | 0.07% |
| Feb. 10, 2026 | Stephenson Pamela | Chief Commercial Officer | A | Common Stock | 17000 | $0.00 | 86,529.0000 | 37,750,162 | 24.45% | 0.05% |
| Jan. 20, 2026 | Khara Rahul | Chief Legal Officer | M | Stock Option (Right to Buy) | 1000 | $0.00 | 21,270.0000 | 37,750,162 | 4.49% | 0.00% |
| Jan. 20, 2026 | Khara Rahul | Chief Legal Officer | S | Common Stock | 1000 | $69.74 | 37,793.0000 | 37,750,162 | 2.58% | 0.00% |
| Jan. 20, 2026 | Khara Rahul | Chief Legal Officer | M | Common Stock | 1000 | $13.50 | 38,793.0000 | 37,750,162 | 2.65% | 0.00% |
| Jan. 2, 2026 | Khara Rahul | Chief Legal Officer | M | Stock Option (Right to Buy) | 6500 | $0.00 | 22,270.0000 | 37,750,162 | 22.59% | 0.02% |
| Jan. 2, 2026 | Khara Rahul | Chief Legal Officer | S | Common Stock | 1157 | $79.27 | 37,793.0000 | 37,750,162 | 2.97% | 0.00% |
| Jan. 2, 2026 | Khara Rahul | Chief Legal Officer | S | Common Stock | 4993 | $78.62 | 38,950.0000 | 37,750,162 | 11.36% | 0.01% |
| Jan. 2, 2026 | Khara Rahul | Chief Legal Officer | S | Common Stock | 350 | $77.67 | 43,943.0000 | 37,750,162 | 0.79% | 0.00% |
| Jan. 2, 2026 | Khara Rahul | Chief Legal Officer | M | Common Stock | 6500 | $13.50 | 44,293.0000 | 37,750,162 | 17.20% | 0.02% |
| Dec. 22, 2025 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 99 | $0.00 | 29,905.0000 | 37,750,162 | 0.33% | 0.00% |
| Dec. 22, 2025 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 219 | $0.00 | 2,628.0000 | 37,750,162 | 7.69% | 0.00% |
| Dec. 22, 2025 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 2825 | $0.00 | 3,550.0000 | 37,750,162 | 44.31% | 0.01% |
| Dec. 22, 2025 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 99 | $13.50 | 78,845.0000 | 37,750,162 | 0.13% | 0.00% |
| Dec. 22, 2025 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 219 | $9.86 | 78,746.0000 | 37,750,162 | 0.28% | 0.00% |
| Dec. 22, 2025 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 2825 | $9.86 | 78,527.0000 | 37,750,162 | 3.73% | 0.01% |
| Dec. 19, 2025 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 12300 | $0.00 | 186,120.0000 | 37,750,162 | 6.20% | 0.03% |
| Dec. 19, 2025 | Quisel John D | Chief Executive Officer | M | Common Stock | 12300 | $1.01 | 184,128.0000 | 37,750,162 | 7.16% | 0.03% |
| Dec. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 148 | $91.47 | 14,013.0000 | 37,750,162 | 1.05% | 0.00% |
| Dec. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 213 | $91.47 | 337,485.0000 | 37,750,162 | 0.06% | 0.00% |
| Dec. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 393 | $91.47 | 349,210.0000 | 37,750,162 | 0.11% | 0.00% |
| Dec. 15, 2025 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 300 | $92.23 | 75,702.0000 | 37,750,162 | 0.39% | 0.00% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 16403 | $92.05 | 425,633.0000 | 37,750,162 | 3.71% | 0.04% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 3852 | $92.58 | 421,781.0000 | 37,750,162 | 0.91% | 0.01% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 3446 | $93.80 | 418,335.0000 | 37,750,162 | 0.82% | 0.01% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 8527 | $92.05 | 377,022.0000 | 37,750,162 | 2.21% | 0.02% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 2005 | $92.58 | 375,017.0000 | 37,750,162 | 0.53% | 0.01% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 1793 | $93.80 | 373,224.0000 | 37,750,162 | 0.48% | 0.00% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 6570 | $92.05 | 44,430.0000 | 37,750,162 | 12.88% | 0.02% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 1540 | $92.58 | 42,890.0000 | 37,750,162 | 3.47% | 0.00% |
| Dec. 12, 2025 | Bitterman Kevin | Director | S | Common Stock | 1371 | $93.80 | 41,519.0000 | 37,750,162 | 3.20% | 0.00% |
| Dec. 15, 2025 | Bitterman Kevin | Director | S | Common Stock | 28913 | $91.18 | 389,422.0000 | 37,750,162 | 6.91% | 0.08% |
| Dec. 15, 2025 | Bitterman Kevin | Director | S | Common Stock | 3921 | $92.01 | 385,501.0000 | 37,750,162 | 1.01% | 0.01% |
| Dec. 15, 2025 | Bitterman Kevin | Director | S | Common Stock | 14811 | $91.18 | 358,413.0000 | 37,750,162 | 3.97% | 0.04% |
| Dec. 15, 2025 | Bitterman Kevin | Director | S | Common Stock | 2049 | $92.01 | 356,364.0000 | 37,750,162 | 0.57% | 0.01% |
| Dec. 15, 2025 | Bitterman Kevin | Director | S | Common Stock | 11427 | $91.18 | 30,092.0000 | 37,750,162 | 27.52% | 0.03% |
| Dec. 15, 2025 | Bitterman Kevin | Director | S | Common Stock | 1572 | $92.01 | 28,520.0000 | 37,750,162 | 5.22% | 0.00% |
| Dec. 15, 2025 | Bitterman Kevin | Director | M | Common Stock | 7000 | $13.50 | 21,161.0000 | 37,750,162 | 49.43% | 0.02% |
| Dec. 15, 2025 | Bitterman Kevin | Director | S | Common Stock | 7000 | $91.87 | 14,161.0000 | 37,750,162 | 33.08% | 0.02% |
| Dec. 16, 2025 | Bitterman Kevin | Director | S | Common Stock | 35898 | $91.24 | 349,603.0000 | 37,750,162 | 9.31% | 0.10% |
| Dec. 16, 2025 | Bitterman Kevin | Director | S | Common Stock | 18666 | $91.24 | 337,698.0000 | 37,750,162 | 5.24% | 0.05% |
| Dec. 16, 2025 | Bitterman Kevin | Director | S | Common Stock | 14359 | $91.24 | 14,161.0000 | 37,750,162 | 50.35% | 0.04% |
| Dec. 15, 2025 | Bitterman Kevin | Director | M | Stock Option (Right to Buy) | 7000 | $0.00 | 0.0000 | 37,750,162 | 100.00% | 0.02% |
| Dec. 15, 2025 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 3642 | $90.60 | 85,153.0000 | 37,750,162 | 4.10% | 0.01% |
| Dec. 15, 2025 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 9151 | $91.44 | 76,002.0000 | 37,750,162 | 10.75% | 0.02% |
| Dec. 11, 2025 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 40000 | $0.00 | 75,375.0000 | 37,750,162 | 34.67% | 0.11% |
| Dec. 11, 2025 | Quisel John D | Chief Executive Officer | S | Common Stock | 16888 | $93.65 | 171,828.0000 | 37,750,162 | 8.95% | 0.04% |
| Dec. 11, 2025 | Quisel John D | Chief Executive Officer | S | Common Stock | 16356 | $92.96 | 188,716.0000 | 37,750,162 | 7.98% | 0.04% |
| Dec. 11, 2025 | Quisel John D | Chief Executive Officer | S | Common Stock | 4337 | $92.21 | 205,072.0000 | 37,750,162 | 2.07% | 0.01% |
| Dec. 11, 2025 | Quisel John D | Chief Executive Officer | S | Common Stock | 2419 | $90.97 | 209,409.0000 | 37,750,162 | 1.14% | 0.01% |
| Dec. 11, 2025 | Quisel John D | Chief Executive Officer | M | Common Stock | 40000 | $9.86 | 211,828.0000 | 37,750,162 | 23.28% | 0.11% |
| Nov. 11, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | S | Common Stock | 8040 | $85.91 | 40,555.0000 | 37,750,162 | 16.54% | 0.02% |
| Nov. 11, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | M | Common Stock | 30000 | $2.65 | 70,555.0000 | 37,750,162 | 73.97% | 0.08% |
| Nov. 11, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | M | Stock Option (Right to Buy) | 30000 | $0.00 | 7,941.0000 | 37,750,162 | 79.07% | 0.08% |
| Nov. 11, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | S | Common Stock | 8015 | $83.15 | 62,540.0000 | 37,750,162 | 11.36% | 0.02% |
| Nov. 11, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | S | Common Stock | 9360 | $85.33 | 48,595.0000 | 37,750,162 | 16.15% | 0.02% |
| Nov. 11, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | S | Common Stock | 4585 | $83.99 | 57,955.0000 | 37,750,162 | 7.33% | 0.01% |
| Oct. 22, 2025 | AI DMI LLC | Not found | S | Common Stock | 744047 | $80.47 | 2,814,379.0000 | 34,569,042 | 20.91% | 2.15% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 5066 | $87.37 | 518,845.0000 | 34,569,042 | 0.97% | 0.01% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 5065 | $87.37 | 462,359.0000 | 34,569,042 | 1.08% | 0.01% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 13014 | $88.91 | 505,831.0000 | 34,569,042 | 2.51% | 0.04% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 13014 | $88.91 | 449,345.0000 | 34,569,042 | 2.81% | 0.04% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 2251 | $89.70 | 503,580.0000 | 34,569,042 | 0.45% | 0.01% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 2251 | $89.70 | 447,094.0000 | 34,569,042 | 0.50% | 0.01% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 10094 | $90.66 | 493,486.0000 | 34,569,042 | 2.00% | 0.03% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 10095 | $90.66 | 436,999.0000 | 34,569,042 | 2.26% | 0.03% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 450 | $91.88 | 493,036.0000 | 34,569,042 | 0.09% | 0.00% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 450 | $91.88 | 436,549.0000 | 34,569,042 | 0.10% | 0.00% |
| Oct. 15, 2025 | Bitterman Kevin | Not found | S | Common Stock | 19542 | $77.16 | 532,079.0000 | 34,569,042 | 3.54% | 0.06% |
| Oct. 15, 2025 | Bitterman Kevin | Not found | S | Common Stock | 2618 | $77.76 | 529,461.0000 | 34,569,042 | 0.49% | 0.01% |
| Oct. 16, 2025 | Bitterman Kevin | Not found | S | Common Stock | 1425 | $77.11 | 528,036.0000 | 34,569,042 | 0.27% | 0.00% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 1125 | $84.89 | 526,911.0000 | 34,569,042 | 0.21% | 0.00% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 1125 | $84.89 | 470,424.0000 | 34,569,042 | 0.24% | 0.00% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 3000 | $86.13 | 523,911.0000 | 34,569,042 | 0.57% | 0.01% |
| Oct. 17, 2025 | Bitterman Kevin | Not found | S | Common Stock | 3000 | $86.13 | 467,424.0000 | 34,569,042 | 0.64% | 0.01% |
| Oct. 8, 2025 | Bitterman Kevin | Not found | S | Common Stock | 12689 | $71.51 | 985,437.0000 | 34,569,042 | 1.27% | 0.04% |
| Oct. 8, 2025 | Bitterman Kevin | Not found | S | Common Stock | 13267 | $72.39 | 972,170.0000 | 34,569,042 | 1.35% | 0.04% |
| Oct. 8, 2025 | Bitterman Kevin | Not found | S | Common Stock | 25400 | $70.54 | 998,126.0000 | 34,569,042 | 2.48% | 0.07% |
| Oct. 8, 2025 | Bitterman Kevin | Not found | S | Common Stock | 12386 | $69.31 | 1,023,526.0000 | 34,569,042 | 1.20% | 0.04% |
| Oct. 8, 2025 | Bitterman Kevin | Not found | S | Common Stock | 8219 | $68.26 | 1,035,912.0000 | 34,569,042 | 0.79% | 0.02% |
| Oct. 7, 2025 | Bitterman Kevin | Not found | S | Common Stock | 6661 | $69.01 | 1,044,131.0000 | 34,569,042 | 0.63% | 0.02% |
| Oct. 7, 2025 | Bitterman Kevin | Not found | S | Common Stock | 11378 | $68.01 | 1,050,792.0000 | 34,569,042 | 1.07% | 0.03% |
| Sept. 16, 2025 | GEMAYEL GEORGES | Not found | A | Stock Option (Right to Buy) | 1000 | $0.00 | 1,000.0000 | 34,569,042 | 9999.99% | 0.00% |
| Sept. 9, 2025 | Quisel John D | Chief Executive Officer | M | Common Stock | 10000 | $1.01 | 171,828.0000 | 34,569,042 | 6.18% | 0.03% |
| Sept. 9, 2025 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 10000 | $0.00 | 198,420.0000 | 34,569,042 | 4.80% | 0.03% |
| Aug. 22, 2025 | Bitterman Kevin | Not found | S | Common Stock | 2287 | $61.03 | 1,062,170.0000 | 34,569,042 | 0.21% | 0.01% |
| Aug. 14, 2025 | Bitterman Kevin | Not found | S | Common Stock | 7212 | $60.99 | 1,064,457.0000 | 34,569,042 | 0.67% | 0.02% |
| Aug. 13, 2025 | Bitterman Kevin | Not found | S | Common Stock | 24962 | $61.15 | 1,071,669.0000 | 34,569,042 | 2.28% | 0.07% |
| Aug. 5, 2025 | Bitterman Kevin | Not found | S | Common Stock | 395 | $60.95 | 1,096,631.0000 | 34,569,042 | 0.04% | 0.00% |
| July 30, 2025 | Bitterman Kevin | Not found | S | Common Stock | 8492 | $61.04 | 1,097,026.0000 | 34,569,042 | 0.77% | 0.02% |
| July 23, 2025 | Bitterman Kevin | Not found | S | Common Stock | 29837 | $60.97 | 1,118,551.0000 | 34,569,042 | 2.60% | 0.09% |
| July 24, 2025 | Bitterman Kevin | Not found | S | Common Stock | 13033 | $61.17 | 1,105,518.0000 | 34,569,042 | 1.17% | 0.04% |
| July 18, 2025 | Bitterman Kevin | Not found | S | Common Stock | 664 | $61.13 | 1,148,388.0000 | 34,569,042 | 0.06% | 0.00% |
| July 17, 2025 | Franchi Jean M. | Chief Financial Officer | S | Common Stock | 2031 | $59.00 | 63,499.0000 | 34,569,042 | 3.10% | 0.01% |
| July 14, 2025 | AHMED NADIM | Not found | A | Stock Option (Right to Buy) | 20000 | $0.00 | 20,000.0000 | 34,569,042 | 9999.99% | 0.06% |
| July 10, 2025 | Franchi Jean M. | Chief Financial Officer | S | Common Stock | 2000 | $57.50 | 65,530.0000 | 34,569,042 | 2.96% | 0.01% |
| July 9, 2025 | Quisel John D | Chief Executive Officer | S | Common Stock | 3593 | $56.20 | 161,828.0000 | 34,569,042 | 2.17% | 0.01% |
| July 9, 2025 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 34800 | $0.00 | 115,375.0000 | 34,569,042 | 23.17% | 0.10% |
| July 9, 2025 | Quisel John D | Chief Executive Officer | S | Common Stock | 31207 | $55.23 | 165,421.0000 | 34,569,042 | 15.87% | 0.09% |
| July 9, 2025 | Quisel John D | Chief Executive Officer | M | Common Stock | 34800 | $9.86 | 196,628.0000 | 34,569,042 | 21.50% | 0.10% |
| July 3, 2025 | Quisel John D | Chief Executive Officer | M | Common Stock | 5200 | $9.86 | 167,028.0000 | 34,569,042 | 3.21% | 0.02% |
| July 3, 2025 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 5200 | $0.00 | 150,175.0000 | 34,569,042 | 3.35% | 0.02% |
| July 3, 2025 | Quisel John D | Chief Executive Officer | S | Common Stock | 5200 | $55.09 | 161,828.0000 | 34,569,042 | 3.11% | 0.02% |
| June 27, 2025 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 2411 | $0.00 | 2,847.0000 | 34,569,042 | 45.85% | 0.01% |
| June 27, 2025 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 2411 | $9.86 | 88,795.0000 | 34,569,042 | 2.79% | 0.01% |
| June 27, 2025 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 29659 | $9.86 | 86,384.0000 | 34,569,042 | 52.29% | 0.09% |
| June 27, 2025 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 29659 | $0.00 | 6,375.0000 | 34,569,042 | 82.31% | 0.09% |
| June 16, 2025 | Franchi Jean M. | Chief Financial Officer | S | Common Stock | 2000 | $52.26 | 67,530.0000 | 34,569,042 | 2.88% | 0.01% |
| June 11, 2025 | Bitterman Kevin | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 34,569,042 | 9999.99% | 0.03% |
| June 11, 2025 | GEMAYEL GEORGES | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 34,569,042 | 9999.99% | 0.03% |
| June 11, 2025 | Nicholson Donald William | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 34,569,042 | 9999.99% | 0.03% |
| June 11, 2025 | Ratcliffe Liam | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 34,569,042 | 9999.99% | 0.03% |
| June 11, 2025 | White William Richard | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 34,569,042 | 9999.99% | 0.03% |
| June 11, 2025 | Ashiya Mona | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 34,569,042 | 9999.99% | 0.03% |
| June 11, 2025 | Chin Mark | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 34,569,042 | 9999.99% | 0.03% |
| June 6, 2025 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 2996 | $50.00 | 56,725.0000 | 34,569,042 | 5.02% | 0.01% |
| May 20, 2025 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 6677 | $50.04 | 59,721.0000 | 34,569,042 | 10.06% | 0.02% |
| May 2, 2025 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 2100 | $50.17 | 66,398.0000 | 34,569,042 | 3.07% | 0.01% |
| April 7, 2025 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 7000 | $0.00 | 208,420.0000 | 34,569,042 | 3.25% | 0.02% |
| April 7, 2025 | Quisel John D | Chief Executive Officer | M | Common Stock | 7000 | $1.01 | 161,828.0000 | 34,569,042 | 4.52% | 0.02% |
| March 24, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 1956 | $54.11 | 482,308.0000 | 34,569,042 | 0.40% | 0.01% |
| March 24, 2025 | Ashiya Mona | Director | S | Common Stock | 756 | $54.11 | 186,541.0000 | 34,569,042 | 0.40% | 0.00% |
| March 24, 2025 | Ashiya Mona | Director | S | Common Stock | 3026 | $54.11 | 746,171.0000 | 34,569,042 | 0.40% | 0.01% |
| March 24, 2025 | Ashiya Mona | Director | S | Common Stock | 1956 | $54.11 | 482,308.0000 | 34,569,042 | 0.40% | 0.01% |
| March 24, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 756 | $54.11 | 186,541.0000 | 34,569,042 | 0.40% | 0.00% |
| March 24, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 3026 | $54.11 | 746,171.0000 | 34,569,042 | 0.40% | 0.01% |
| March 20, 2025 | Ashiya Mona | Director | S | Common Stock | 941 | $54.01 | 487,676.0000 | 34,569,042 | 0.19% | 0.00% |
| March 19, 2025 | Ashiya Mona | Director | S | Common Stock | 5228 | $54.02 | 188,981.0000 | 34,569,042 | 2.69% | 0.02% |
| March 19, 2025 | Ashiya Mona | Director | S | Common Stock | 20911 | $54.02 | 755,933.0000 | 34,569,042 | 2.69% | 0.06% |
| March 19, 2025 | Ashiya Mona | Director | S | Common Stock | 13517 | $54.02 | 488,617.0000 | 34,569,042 | 2.69% | 0.04% |
| March 19, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 5228 | $54.02 | 188,981.0000 | 34,569,042 | 2.69% | 0.02% |
| March 21, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 1320 | $54.00 | 187,297.0000 | 34,569,042 | 0.70% | 0.00% |
| March 20, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 941 | $54.01 | 487,676.0000 | 34,569,042 | 0.19% | 0.00% |
| March 20, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 1457 | $54.01 | 754,476.0000 | 34,569,042 | 0.19% | 0.00% |
| March 20, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 364 | $54.01 | 188,617.0000 | 34,569,042 | 0.19% | 0.00% |
| March 21, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 3412 | $54.00 | 484,264.0000 | 34,569,042 | 0.70% | 0.01% |
| March 21, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 5279 | $54.00 | 749,197.0000 | 34,569,042 | 0.70% | 0.02% |
| March 19, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 13517 | $54.02 | 488,617.0000 | 34,569,042 | 2.69% | 0.04% |
| March 19, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 20911 | $54.02 | 755,933.0000 | 34,569,042 | 2.69% | 0.06% |
| March 21, 2025 | Ashiya Mona | Director | S | Common Stock | 1320 | $54.00 | 187,297.0000 | 34,569,042 | 0.70% | 0.00% |
| March 21, 2025 | Ashiya Mona | Director | S | Common Stock | 5279 | $54.00 | 749,197.0000 | 34,569,042 | 0.70% | 0.02% |
| March 21, 2025 | Ashiya Mona | Director | S | Common Stock | 3412 | $54.00 | 484,264.0000 | 34,569,042 | 0.70% | 0.01% |
| March 20, 2025 | Ashiya Mona | Director | S | Common Stock | 364 | $54.01 | 188,617.0000 | 34,569,042 | 0.19% | 0.00% |
| March 20, 2025 | Ashiya Mona | Director | S | Common Stock | 1457 | $54.01 | 754,476.0000 | 34,569,042 | 0.19% | 0.00% |
| March 11, 2025 | Ashiya Mona | Director | S | Common Stock | 3567 | $54.01 | 205,175.0000 | 34,569,042 | 1.71% | 0.01% |
| March 10, 2025 | Ashiya Mona | Director | S | Common Stock | 68766 | $54.29 | 539,845.0000 | 34,569,042 | 11.30% | 0.20% |
| March 10, 2025 | Ashiya Mona | Director | S | Common Stock | 106384 | $54.29 | 835,185.0000 | 34,569,042 | 11.30% | 0.31% |
| March 10, 2025 | Ashiya Mona | Director | S | Common Stock | 26596 | $54.29 | 208,795.0000 | 34,569,042 | 11.30% | 0.08% |
| March 10, 2025 | Ashiya Mona | Director | S | Common Stock | 136 | $55.01 | 539,709.0000 | 34,569,042 | 0.03% | 0.00% |
| March 10, 2025 | Ashiya Mona | Director | S | Common Stock | 211 | $55.01 | 834,974.0000 | 34,569,042 | 0.03% | 0.00% |
| March 10, 2025 | Ashiya Mona | Director | S | Common Stock | 53 | $55.01 | 208,742.0000 | 34,569,042 | 0.03% | 0.00% |
| March 11, 2025 | Ashiya Mona | Director | S | Common Stock | 9222 | $54.01 | 530,487.0000 | 34,569,042 | 1.71% | 0.03% |
| March 11, 2025 | Ashiya Mona | Director | S | Common Stock | 14267 | $54.01 | 820,707.0000 | 34,569,042 | 1.71% | 0.04% |
| March 12, 2025 | Ashiya Mona | Director | S | Common Stock | 603 | $55.05 | 529,884.0000 | 34,569,042 | 0.11% | 0.00% |
| March 12, 2025 | Ashiya Mona | Director | S | Common Stock | 933 | $55.05 | 819,774.0000 | 34,569,042 | 0.11% | 0.00% |
| March 12, 2025 | Ashiya Mona | Director | S | Common Stock | 233 | $55.05 | 204,942.0000 | 34,569,042 | 0.11% | 0.00% |
| March 12, 2025 | Ashiya Mona | Director | S | Common Stock | 27750 | $54.44 | 502,134.0000 | 34,569,042 | 5.24% | 0.08% |
| March 12, 2025 | Ashiya Mona | Director | S | Common Stock | 42930 | $54.44 | 776,844.0000 | 34,569,042 | 5.24% | 0.12% |
| March 12, 2025 | Ashiya Mona | Director | S | Common Stock | 10733 | $54.44 | 194,209.0000 | 34,569,042 | 5.24% | 0.03% |
| March 10, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 68766 | $54.29 | 539,845.0000 | 34,569,042 | 11.30% | 0.20% |
| March 10, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 106384 | $54.29 | 835,185.0000 | 34,569,042 | 11.30% | 0.31% |
| March 10, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 26596 | $54.29 | 208,795.0000 | 34,569,042 | 11.30% | 0.08% |
| March 10, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 136 | $55.01 | 539,709.0000 | 34,569,042 | 0.03% | 0.00% |
| March 10, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 211 | $55.01 | 834,974.0000 | 34,569,042 | 0.03% | 0.00% |
| March 10, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 53 | $55.01 | 208,742.0000 | 34,569,042 | 0.03% | 0.00% |
| March 11, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 9222 | $54.01 | 530,487.0000 | 34,569,042 | 1.71% | 0.03% |
| March 11, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 14267 | $54.01 | 820,707.0000 | 34,569,042 | 1.71% | 0.04% |
| March 11, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 3567 | $54.01 | 205,175.0000 | 34,569,042 | 1.71% | 0.01% |
| March 12, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 603 | $55.05 | 529,884.0000 | 34,569,042 | 0.11% | 0.00% |
| March 12, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 933 | $55.05 | 819,774.0000 | 34,569,042 | 0.11% | 0.00% |
| March 12, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 233 | $55.05 | 204,942.0000 | 34,569,042 | 0.11% | 0.00% |
| March 12, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 27750 | $54.44 | 502,134.0000 | 34,569,042 | 5.24% | 0.08% |
| March 12, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 42930 | $54.44 | 776,844.0000 | 34,569,042 | 5.24% | 0.12% |
| March 12, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 10733 | $54.44 | 194,209.0000 | 34,569,042 | 5.24% | 0.03% |
| Feb. 18, 2025 | Khara Rahul | Chief Legal Officer | S | Common Stock | 1161 | $54.58 | 37,583.0000 | 0 | 3.00% | 0.00% |
| Feb. 18, 2025 | Stephenson Pamela | Chief Commercial Officer | S | Common Stock | 3137 | $54.58 | 69,529.0000 | 0 | 4.32% | 0.00% |
| Feb. 18, 2025 | Franchi Jean M. | Chief Financial Officer | S | Common Stock | 3136 | $54.58 | 69,530.0000 | 0 | 4.32% | 0.00% |
| Feb. 18, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | S | Common Stock | 1610 | $54.58 | 40,555.0000 | 0 | 3.82% | 0.00% |
| Feb. 18, 2025 | Quisel John D | Chief Executive Officer | S | Common Stock | 5574 | $54.58 | 154,828.0000 | 0 | 3.48% | 0.00% |
| Feb. 18, 2025 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1638 | $54.58 | 68,498.0000 | 0 | 2.34% | 0.00% |
| Feb. 10, 2025 | Khara Rahul | Chief Legal Officer | A | Stock Option (Right to Buy) | 36000 | $0.00 | 36,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | A | Common Stock | 24000 | $0.00 | 42,165.0000 | 0 | 132.12% | 0.00% |
| Feb. 10, 2025 | Yu Jonathan Yen-Wen | Chief Operating Officer | A | Stock Option (Right to Buy) | 36000 | $0.00 | 36,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | Franchi Jean M. | Chief Financial Officer | A | Common Stock | 36000 | $0.00 | 72,666.0000 | 0 | 98.18% | 0.00% |
| Feb. 10, 2025 | Franchi Jean M. | Chief Financial Officer | A | Stock Option (Right to Buy) | 36000 | $0.00 | 36,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | Quisel John D | Chief Executive Officer | A | Common Stock | 78337 | $0.00 | 160,402.0000 | 0 | 95.46% | 0.00% |
| Feb. 10, 2025 | Quisel John D | Chief Executive Officer | A | Stock Option (Right to Buy) | 117505 | $0.00 | 117,505.0000 | 0 | 9999.99% | 0.00% |
| Feb. 3, 2025 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 4233 | $2.65 | 44,638.0000 | 0 | 10.48% | 0.00% |
| Feb. 3, 2025 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 1498 | $2.65 | 46,136.0000 | 0 | 3.36% | 0.00% |
| Feb. 3, 2025 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 4233 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Savage William Jacob | Chief Medical Officer | A | Common Stock | 24000 | $0.00 | 70,136.0000 | 0 | 52.02% | 0.00% |
| Feb. 3, 2025 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 1498 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Savage William Jacob | Chief Medical Officer | A | Stock Option (Right to Buy) | 36000 | $0.00 | 36,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | Stephenson Pamela | Chief Commercial Officer | A | Common Stock | 36000 | $0.00 | 72,666.0000 | 0 | 98.18% | 0.00% |
| Feb. 10, 2025 | Stephenson Pamela | Chief Commercial Officer | A | Stock Option (Right to Buy) | 36000 | $0.00 | 36,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | Khara Rahul | Chief Legal Officer | A | Common Stock | 24000 | $0.00 | 38,035.0000 | 0 | 171.00% | 0.00% |
| Feb. 3, 2025 | Khara Rahul | Chief Legal Officer | M | Common Stock | 7500 | $14.69 | 21,535.0000 | 0 | 53.44% | 0.00% |
| Feb. 3, 2025 | Khara Rahul | Chief Legal Officer | S | Common Stock | 1813 | $56.01 | 14,035.0000 | 0 | 11.44% | 0.00% |
| Feb. 3, 2025 | Khara Rahul | Chief Legal Officer | M | Stock Option (Right to Buy) | 7500 | $0.00 | 64,804.0000 | 0 | 10.37% | 0.00% |
| Feb. 3, 2025 | Khara Rahul | Chief Legal Officer | S | Common Stock | 5687 | $55.40 | 15,848.0000 | 0 | 26.41% | 0.00% |
| Jan. 2, 2025 | Khara Rahul | Chief Legal Officer | S | Common Stock | 4000 | $61.96 | 17,535.0000 | 0 | 18.57% | 0.00% |
| Jan. 2, 2025 | Khara Rahul | Chief Legal Officer | S | Common Stock | 2100 | $64.13 | 14,035.0000 | 0 | 13.02% | 0.00% |
| Jan. 2, 2025 | Khara Rahul | Chief Legal Officer | M | Stock Option (Right to Buy) | 7500 | $0.00 | 72,304.0000 | 0 | 9.40% | 0.00% |
| Jan. 2, 2025 | Khara Rahul | Chief Legal Officer | M | Common Stock | 7500 | $14.69 | 21,535.0000 | 0 | 53.44% | 0.00% |
| Jan. 2, 2025 | Khara Rahul | Chief Legal Officer | S | Common Stock | 1400 | $62.95 | 16,135.0000 | 0 | 7.98% | 0.00% |
| Dec. 30, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 1900 | $62.41 | 72,065.0000 | 0 | 2.57% | 0.00% |
| Dec. 31, 2024 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 10000 | $0.00 | 215,420.0000 | 0 | 4.44% | 0.00% |
| Dec. 30, 2024 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 13012 | $0.00 | 155,375.0000 | 0 | 7.73% | 0.00% |
| Dec. 30, 2024 | Quisel John D | Chief Executive Officer | M | Common Stock | 13012 | $9.86 | 85,077.0000 | 0 | 18.06% | 0.00% |
| Dec. 30, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 11112 | $61.87 | 73,965.0000 | 0 | 13.06% | 0.00% |
| Dec. 31, 2024 | Quisel John D | Chief Executive Officer | M | Common Stock | 10000 | $1.01 | 82,065.0000 | 0 | 13.88% | 0.00% |
| Dec. 23, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 3414 | $62.38 | 88,471.0000 | 0 | 3.72% | 0.00% |
| Dec. 23, 2024 | Quisel John D | Chief Executive Officer | M | Common Stock | 19820 | $2.65 | 91,885.0000 | 0 | 27.50% | 0.00% |
| Dec. 23, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 12194 | $63.12 | 76,277.0000 | 0 | 13.78% | 0.00% |
| Dec. 23, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 4212 | $63.80 | 72,065.0000 | 0 | 5.52% | 0.00% |
| Dec. 23, 2024 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 19820 | $0.00 | 41,830.0000 | 0 | 32.15% | 0.00% |
| Dec. 16, 2024 | Quisel John D | Chief Executive Officer | M | Common Stock | 12791 | $1.01 | 84,856.0000 | 0 | 17.75% | 0.00% |
| Dec. 16, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 219 | $64.66 | 84,637.0000 | 0 | 0.26% | 0.00% |
| Dec. 16, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 500 | $67.20 | 72,065.0000 | 0 | 0.69% | 0.00% |
| Dec. 16, 2024 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 12791 | $0.00 | 225,420.0000 | 0 | 5.37% | 0.00% |
| Dec. 16, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 5767 | $65.58 | 78,870.0000 | 0 | 6.81% | 0.00% |
| Dec. 16, 2024 | Quisel John D | Chief Executive Officer | S | Common Stock | 6305 | $66.35 | 72,565.0000 | 0 | 7.99% | 0.00% |
| Dec. 2, 2024 | White William Richard | Not found | M | Common Stock | 1756 | $2.65 | 1,756.0000 | 0 | 9999.99% | 0.00% |
| Dec. 2, 2024 | White William Richard | Not found | M | Common Stock | 201 | $9.86 | 1,957.0000 | 0 | 11.45% | 0.00% |
| Dec. 2, 2024 | White William Richard | Not found | S | Common Stock | 22 | $63.49 | 1,935.0000 | 0 | 1.12% | 0.00% |
| Dec. 2, 2024 | White William Richard | Not found | S | Common Stock | 1762 | $64.58 | 173.0000 | 0 | 91.06% | 0.00% |
| Dec. 2, 2024 | White William Richard | Not found | S | Common Stock | 173 | $65.33 | 0.0000 | 0 | 100.00% | 0.00% |
| Dec. 2, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 1756 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Dec. 2, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 201 | $0.00 | 1,804.0000 | 0 | 10.02% | 0.00% |
| Nov. 25, 2024 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 8737 | $64.98 | 45,851.0000 | 0 | 16.01% | 0.00% |
| Nov. 25, 2024 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 5263 | $0.00 | 5,258.0000 | 0 | 50.02% | 0.00% |
| Nov. 25, 2024 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1904 | $67.02 | 40,405.0000 | 0 | 4.50% | 0.00% |
| Nov. 25, 2024 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 8920 | $0.00 | 30,004.0000 | 0 | 22.92% | 0.00% |
| Nov. 25, 2024 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 3542 | $65.79 | 42,309.0000 | 0 | 7.73% | 0.00% |
| Nov. 25, 2024 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 5263 | $9.86 | 45,668.0000 | 0 | 13.03% | 0.00% |
| Nov. 25, 2024 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 8920 | $13.50 | 54,588.0000 | 0 | 19.53% | 0.00% |
| Nov. 15, 2024 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 100 | $61.10 | 40,405.0000 | 0 | 0.25% | 0.00% |
| Nov. 15, 2024 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1219 | $60.16 | 40,505.0000 | 0 | 2.92% | 0.00% |
| Nov. 15, 2024 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 7839 | $59.54 | 41,724.0000 | 0 | 15.82% | 0.00% |
| Nov. 15, 2024 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 9158 | $9.86 | 49,563.0000 | 0 | 22.67% | 0.00% |
| Nov. 15, 2024 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 9158 | $0.00 | 36,034.0000 | 0 | 20.26% | 0.00% |
| Nov. 1, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 201 | $0.00 | 2,005.0000 | 0 | 9.11% | 0.00% |
| Nov. 4, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 7136 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Nov. 1, 2024 | White William Richard | Not found | S | Common Stock | 72 | $45.68 | 129.0000 | 0 | 35.82% | 0.00% |
| Nov. 1, 2024 | White William Richard | Not found | M | Common Stock | 201 | $9.86 | 201.0000 | 0 | 9999.99% | 0.00% |
| Nov. 1, 2024 | White William Richard | Not found | S | Common Stock | 129 | $46.75 | 0.0000 | 0 | 100.00% | 0.00% |
| Nov. 4, 2024 | White William Richard | Not found | M | Common Stock | 7136 | $45.69 | 7,136.0000 | 0 | 9999.99% | 0.00% |
| Nov. 4, 2024 | White William Richard | Not found | S | Common Stock | 1790 | $57.59 | 5,346.0000 | 0 | 25.08% | 0.00% |
| Nov. 4, 2024 | White William Richard | Not found | S | Common Stock | 5346 | $58.94 | 0.0000 | 0 | 100.00% | 0.00% |
| Oct. 1, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 201 | $0.00 | 2,206.0000 | 0 | 8.35% | 0.00% |
| Oct. 1, 2024 | White William Richard | Not found | S | Common Stock | 50 | $51.51 | 79.0000 | 0 | 38.76% | 0.00% |
| Oct. 1, 2024 | White William Richard | Not found | S | Common Stock | 40 | $50.45 | 129.0000 | 0 | 23.67% | 0.00% |
| Oct. 1, 2024 | White William Richard | Not found | S | Common Stock | 32 | $49.03 | 169.0000 | 0 | 15.92% | 0.00% |
| Oct. 1, 2024 | White William Richard | Not found | M | Common Stock | 201 | $9.86 | 201.0000 | 0 | 9999.99% | 0.00% |
| Oct. 1, 2024 | White William Richard | Not found | S | Common Stock | 79 | $52.53 | 0.0000 | 0 | 100.00% | 0.00% |
| Sept. 16, 2024 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1500 | $47.41 | 40,405.0000 | 0 | 3.58% | 0.00% |
| Sept. 3, 2024 | White William Richard | Not found | M | Common Stock | 1756 | $2.65 | 1,957.0000 | 0 | 873.63% | 0.00% |
| Sept. 3, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 1756 | $0.00 | 1,756.0000 | 0 | 50.00% | 0.00% |
| Sept. 3, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 201 | $0.00 | 2,407.0000 | 0 | 7.71% | 0.00% |
| Sept. 3, 2024 | White William Richard | Not found | S | Common Stock | 10 | $52.28 | 0.0000 | 0 | 100.00% | 0.00% |
| Sept. 3, 2024 | White William Richard | Not found | S | Common Stock | 50 | $51.54 | 10.0000 | 0 | 83.33% | 0.00% |
| Sept. 3, 2024 | White William Richard | Not found | S | Common Stock | 337 | $50.29 | 60.0000 | 0 | 84.89% | 0.00% |
| Sept. 3, 2024 | White William Richard | Not found | S | Common Stock | 1560 | $49.43 | 397.0000 | 0 | 79.71% | 0.00% |
| Sept. 3, 2024 | White William Richard | Not found | M | Common Stock | 201 | $9.86 | 201.0000 | 0 | 9999.99% | 0.00% |
| Sept. 3, 2024 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1500 | $50.59 | 41,905.0000 | 0 | 3.46% | 0.00% |
| Aug. 1, 2024 | White William Richard | Not found | M | Common Stock | 201 | $9.86 | 201.0000 | 0 | 9999.99% | 0.00% |
| Aug. 1, 2024 | White William Richard | Not found | S | Common Stock | 144 | $43.24 | 57.0000 | 0 | 71.64% | 0.00% |
| Aug. 1, 2024 | White William Richard | Not found | S | Common Stock | 57 | $43.95 | 0.0000 | 0 | 100.00% | 0.00% |
| Aug. 1, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 201 | $0.00 | 2,608.0000 | 0 | 7.16% | 0.00% |
| July 8, 2024 | Quisel John D | Chief Executive Officer | M | Common Stock | 3000 | $1.01 | 72,065.0000 | 0 | 4.34% | 0.00% |
| July 8, 2024 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 3000 | $0.00 | 238,211.0000 | 0 | 1.24% | 0.00% |
| July 1, 2024 | White William Richard | Not found | M | Common Stock | 201 | $9.86 | 201.0000 | 0 | 9999.99% | 0.00% |
| July 1, 2024 | White William Richard | Not found | S | Common Stock | 18 | $45.07 | 183.0000 | 0 | 8.96% | 0.00% |
| July 1, 2024 | White William Richard | Not found | S | Common Stock | 109 | $45.92 | 74.0000 | 0 | 59.56% | 0.00% |
| July 1, 2024 | White William Richard | Not found | S | Common Stock | 74 | $46.45 | 0.0000 | 0 | 100.00% | 0.00% |
| July 1, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 201 | $0.00 | 2,809.0000 | 0 | 6.68% | 0.00% |
| June 17, 2024 | ORBIMED ADVISORS LLC | Director | P | Common Stock | 43944 | $36.00 | 941,569.0000 | 0 | 4.90% | 0.00% |
| June 17, 2024 | ORBIMED ADVISORS LLC | Director | P | Common Stock | 10986 | $36.00 | 235,391.0000 | 0 | 4.90% | 0.00% |
| June 17, 2024 | AI DMI LLC | Not found | A | Common Stock | 416667 | $36.00 | 3,558,426.0000 | 0 | 13.26% | 0.00% |
| June 17, 2024 | ORBIMED ADVISORS LLC | Director | P | Common Stock | 28404 | $36.00 | 608,611.0000 | 0 | 4.90% | 0.00% |
| June 17, 2024 | Ashiya Mona | Director | P | Common Stock | 10986 | $36.00 | 235,391.0000 | 0 | 4.90% | 0.00% |
| June 17, 2024 | Ashiya Mona | Director | P | Common Stock | 43944 | $36.00 | 941,569.0000 | 0 | 4.90% | 0.00% |
| June 17, 2024 | Ashiya Mona | Director | P | Common Stock | 28404 | $36.00 | 608,611.0000 | 0 | 4.90% | 0.00% |
| June 17, 2024 | Bitterman Kevin | Not found | P | Common Stock | 222223 | $36.00 | 1,149,052.0000 | 0 | 23.98% | 0.00% |
| June 12, 2024 | Nicholson Donald William | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Chin Mark | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Ratcliffe Liam | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | GEMAYEL GEORGES | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Bitterman Kevin | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | White William Richard | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2024 | Ashiya Mona | Not found | A | Stock Option (Right to Buy) | 10000 | $0.00 | 10,000.0000 | 0 | 9999.99% | 0.00% |
| June 3, 2024 | White William Richard | Not found | S | Common Stock | 107 | $35.15 | 1,850.0000 | 0 | 5.47% | 0.00% |
| June 3, 2024 | White William Richard | Not found | M | Common Stock | 201 | $9.86 | 1,957.0000 | 0 | 11.45% | 0.00% |
| June 3, 2024 | White William Richard | Not found | M | Common Stock | 1756 | $2.65 | 1,756.0000 | 0 | 9999.99% | 0.00% |
| June 3, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 1756 | $0.00 | 3,512.0000 | 0 | 33.33% | 0.00% |
| June 3, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 201 | $0.00 | 3,010.0000 | 0 | 6.26% | 0.00% |
| June 3, 2024 | White William Richard | Not found | S | Common Stock | 1755 | $36.10 | 95.0000 | 0 | 94.86% | 0.00% |
| June 3, 2024 | White William Richard | Not found | S | Common Stock | 95 | $36.72 | 0.0000 | 0 | 100.00% | 0.00% |
| May 1, 2024 | White William Richard | Not found | S | Common Stock | 39 | $29.11 | 0.0000 | 0 | 100.00% | 0.00% |
| May 1, 2024 | White William Richard | Not found | M | Common Stock | 201 | $9.86 | 201.0000 | 0 | 9999.99% | 0.00% |
| May 1, 2024 | White William Richard | Not found | S | Common Stock | 162 | $28.52 | 39.0000 | 0 | 80.60% | 0.00% |
| May 1, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 201 | $0.00 | 3,211.0000 | 0 | 5.89% | 0.00% |
| April 11, 2024 | White William Richard | Not found | M | Common Stock | 1756 | $2.65 | 1,756.0000 | 0 | 9999.99% | 0.00% |
| April 11, 2024 | White William Richard | Not found | M | Common Stock | 804 | $9.86 | 2,560.0000 | 0 | 45.79% | 0.00% |
| April 11, 2024 | White William Richard | Not found | S | Common Stock | 2482 | $31.79 | 78.0000 | 0 | 96.95% | 0.00% |
| April 11, 2024 | White William Richard | Not found | S | Common Stock | 78 | $32.18 | 0.0000 | 0 | 100.00% | 0.00% |
| April 11, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 1756 | $0.00 | 5,268.0000 | 0 | 25.00% | 0.00% |
| April 11, 2024 | White William Richard | Not found | M | Stock Option (Right to Buy) | 804 | $0.00 | 3,412.0000 | 0 | 19.07% | 0.00% |
| April 10, 2024 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 21870 | $2.65 | 43,405.0000 | 0 | 101.56% | 0.00% |
| April 10, 2024 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 13093 | $0.00 | 4,233.0000 | 0 | 75.57% | 0.00% |
| April 10, 2024 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 8777 | $0.00 | 1,498.0000 | 0 | 85.42% | 0.00% |
| March 5, 2024 | Bitterman Kevin | Not found | S | Common Stock | 26157 | $73.50 | 926,829.0000 | 0 | 2.74% | 0.00% |
| Jan. 10, 2024 | Yu Jonathan Yen-Wen | Chief Business Officer | A | Stock Option (Right to Buy) | 27250 | $0.00 | 27,250.0000 | 0 | 9999.99% | 0.00% |
| Jan. 10, 2024 | Yu Jonathan Yen-Wen | Chief Business Officer | A | Common Stock | 18165 | $0.00 | 18,165.0000 | 0 | 9999.99% | 0.00% |
| Jan. 10, 2024 | Bryce Joanne | Chief Financial Officer | A | Common Stock | 18165 | $0.00 | 23,665.0000 | 0 | 330.27% | 0.00% |
| Jan. 10, 2024 | Bryce Joanne | Chief Financial Officer | A | Stock Option (Right to Buy) | 27250 | $0.00 | 27,250.0000 | 0 | 9999.99% | 0.00% |
| Jan. 10, 2024 | Quisel John D | Chief Executive Officer | A | Common Stock | 66365 | $0.00 | 69,065.0000 | 0 | 2457.96% | 0.00% |
| Jan. 10, 2024 | Khara Rahul | General Counsel | A | Common Stock | 14035 | $0.00 | 14,035.0000 | 0 | 9999.99% | 0.00% |
| Jan. 10, 2024 | Quisel John D | Chief Executive Officer | A | Stock Option (Right to Buy) | 99550 | $0.00 | 99,550.0000 | 0 | 9999.99% | 0.00% |
| Jan. 10, 2024 | Khara Rahul | General Counsel | A | Stock Option (Right to Buy) | 21050 | $0.00 | 21,050.0000 | 0 | 9999.99% | 0.00% |
| Jan. 10, 2024 | Savage William Jacob | Chief Medical Officer | A | Common Stock | 18535 | $0.00 | 21,535.0000 | 0 | 617.83% | 0.00% |
| Jan. 10, 2024 | Savage William Jacob | Chief Medical Officer | A | Stock Option (Right to Buy) | 27800 | $0.00 | 27,800.0000 | 0 | 9999.99% | 0.00% |
| Feb. 26, 2024 | Stephenson Pamela | Chief Commercial Officer | A | Stock Option (Right to Buy) | 55000 | $0.00 | 55,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 26, 2024 | Stephenson Pamela | Chief Commercial Officer | A | Common Stock | 36666 | $0.00 | 36,666.0000 | 0 | 9999.99% | 0.00% |
| Feb. 7, 2024 | Franchi Jean M. | Chief Financial Officer | A | Stock Option (Right to Buy) | 55000 | $0.00 | 55,000.0000 | 0 | 9999.99% | 0.00% |
| Feb. 7, 2024 | Franchi Jean M. | Chief Financial Officer | A | Common Stock | 36666 | $0.00 | 36,666.0000 | 0 | 9999.99% | 0.00% |
| Jan. 23, 2024 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 47500 | $67.65 | 1,600,512.0000 | 0 | 2.88% | 0.00% |
| Jan. 23, 2024 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 82500 | $67.65 | 2,105,846.0000 | 0 | 3.77% | 0.00% |
| Jan. 23, 2024 | Bitterman Kevin | Director | S | Common Stock | 82500 | $67.65 | 754,660.0000 | 0 | 9.85% | 0.00% |
| Jan. 23, 2024 | Bitterman Kevin | Director | S | Common Stock | 20000 | $67.65 | 249,326.0000 | 0 | 7.43% | 0.00% |
| Jan. 23, 2024 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 20000 | $67.65 | 1,600,512.0000 | 0 | 1.23% | 0.00% |
| Jan. 10, 2024 | Bitterman Kevin | Director | S | Common Stock | 20000 | $64.00 | 1,055,486.0000 | 0 | 1.86% | 0.00% |
| Jan. 10, 2024 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 20000 | $64.00 | 2,235,846.0000 | 0 | 0.89% | 0.00% |
| Jan. 10, 2024 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 30000 | $64.00 | 2,235,846.0000 | 0 | 1.32% | 0.00% |
| Dec. 29, 2023 | Quisel John D | Chief Executive Officer | M | Common Stock | 2700 | $1.01 | 2,700.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2023 | Quisel John D | Chief Executive Officer | M | Stock Option (Right to Buy) | 2700 | $0.00 | 241,211.0000 | 0 | 1.11% | 0.00% |
| Dec. 27, 2023 | Bryce Joanne | Chief Financial Officer | M | Stock Option (Right to Buy) | 3000 | $0.00 | 73,745.0000 | 0 | 3.91% | 0.00% |
| Dec. 27, 2023 | Bryce Joanne | Chief Financial Officer | M | Common Stock | 3000 | $9.86 | 5,500.0000 | 0 | 120.00% | 0.00% |
| Dec. 18, 2023 | Ashiya Mona | Director | S | Common Stock | 1724 | $59.24 | 1,702,237.0000 | 0 | 0.10% | 0.00% |
| Dec. 18, 2023 | Ashiya Mona | Director | M | Stock Options (Right to Buy) | 1724 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Dec. 18, 2023 | Ashiya Mona | Director | M | Common Stock | 1724 | $38.00 | 1,703,961.0000 | 0 | 0.10% | 0.00% |
| Dec. 18, 2023 | ORBIMED ADVISORS LLC | Director | M | Stock Options (Right to Buy) | 1724 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Dec. 18, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 1724 | $59.24 | 1,702,237.0000 | 0 | 0.10% | 0.00% |
| Dec. 18, 2023 | ORBIMED ADVISORS LLC | Director | M | Common Stock | 1724 | $38.00 | 1,703,961.0000 | 0 | 0.10% | 0.00% |
| Dec. 14, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 147600 | $56.75 | 580,207.0000 | 0 | 20.28% | 0.00% |
| Dec. 14, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 57100 | $56.75 | 224,405.0000 | 0 | 20.28% | 0.00% |
| Dec. 14, 2023 | Ashiya Mona | Director | S | Common Stock | 147600 | $56.75 | 580,207.0000 | 0 | 20.28% | 0.00% |
| Dec. 14, 2023 | Ashiya Mona | Director | S | Common Stock | 228500 | $56.75 | 897,625.0000 | 0 | 20.29% | 0.00% |
| Dec. 14, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 228500 | $56.75 | 897,625.0000 | 0 | 20.29% | 0.00% |
| Dec. 14, 2023 | Ashiya Mona | Director | S | Common Stock | 57100 | $56.75 | 224,405.0000 | 0 | 20.28% | 0.00% |
| Dec. 12, 2023 | Bitterman Kevin | Director | S | Common Stock | 6599 | $65.77 | 1,099,583.0000 | 0 | 0.60% | 0.00% |
| Dec. 13, 2023 | Bitterman Kevin | Director | S | Common Stock | 3508 | $59.99 | 1,096,075.0000 | 0 | 0.32% | 0.00% |
| Dec. 13, 2023 | Bitterman Kevin | Director | S | Common Stock | 40 | $60.50 | 1,096,035.0000 | 0 | 0.00% | 0.00% |
| Dec. 14, 2023 | Bitterman Kevin | Director | S | Common Stock | 20429 | $58.27 | 1,075,606.0000 | 0 | 1.86% | 0.00% |
| Dec. 14, 2023 | Bitterman Kevin | Director | S | Common Stock | 120 | $59.74 | 1,075,486.0000 | 0 | 0.01% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 31235 | $59.87 | 2,368,710.0000 | 0 | 1.30% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 20823 | $59.87 | 2,341,087.0000 | 0 | 0.88% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 632 | $60.99 | 2,368,078.0000 | 0 | 0.03% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 422 | $60.99 | 2,340,665.0000 | 0 | 0.02% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 6234 | $62.42 | 2,361,844.0000 | 0 | 0.26% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 4155 | $62.42 | 2,336,510.0000 | 0 | 0.18% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 994 | $62.90 | 2,360,850.0000 | 0 | 0.04% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 665 | $62.90 | 2,335,845.0000 | 0 | 0.03% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 1031 | $63.78 | 2,359,819.0000 | 0 | 0.04% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 688 | $63.78 | 2,335,157.0000 | 0 | 0.03% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 27924 | $65.10 | 2,331,895.0000 | 0 | 1.18% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 18615 | $65.10 | 2,316,542.0000 | 0 | 0.80% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 9901 | $65.77 | 2,321,994.0000 | 0 | 0.42% | 0.00% |
| Dec. 12, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 6599 | $65.77 | 2,309,943.0000 | 0 | 0.28% | 0.00% |
| Dec. 13, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 5263 | $59.99 | 2,316,731.0000 | 0 | 0.23% | 0.00% |
| Dec. 13, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 3508 | $59.99 | 2,306,435.0000 | 0 | 0.15% | 0.00% |
| Dec. 13, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 60 | $60.50 | 2,316,671.0000 | 0 | 0.00% | 0.00% |
| Dec. 13, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 40 | $60.50 | 2,306,395.0000 | 0 | 0.00% | 0.00% |
| Dec. 14, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 30645 | $58.27 | 2,286,026.0000 | 0 | 1.32% | 0.00% |
| Dec. 14, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 20429 | $58.27 | 2,285,966.0000 | 0 | 0.89% | 0.00% |
| Dec. 14, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 180 | $59.74 | 2,285,846.0000 | 0 | 0.01% | 0.00% |
| Dec. 14, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 120 | $59.74 | 2,285,846.0000 | 0 | 0.01% | 0.00% |
| Dec. 12, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 14400 | $60.16 | 1,182,425.0000 | 0 | 1.20% | 0.00% |
| Dec. 12, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 9300 | $60.16 | 764,307.0000 | 0 | 1.20% | 0.00% |
| Dec. 12, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 3600 | $60.16 | 295,605.0000 | 0 | 1.20% | 0.00% |
| Dec. 13, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 56200 | $58.56 | 1,126,225.0000 | 0 | 4.75% | 0.00% |
| Dec. 13, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 36400 | $58.56 | 727,907.0000 | 0 | 4.76% | 0.00% |
| Dec. 13, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 14100 | $58.56 | 281,505.0000 | 0 | 4.77% | 0.00% |
| Dec. 14, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 100 | $57.73 | 1,126,125.0000 | 0 | 0.01% | 0.00% |
| Dec. 14, 2023 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 100 | $57.73 | 727,807.0000 | 0 | 0.01% | 0.00% |
| Dec. 12, 2023 | Ashiya Mona | Director | S | Common Stock | 14400 | $60.16 | 1,182,425.0000 | 0 | 1.20% | 0.00% |
| Dec. 12, 2023 | Ashiya Mona | Director | S | Common Stock | 9300 | $60.16 | 764,307.0000 | 0 | 1.20% | 0.00% |
| Dec. 12, 2023 | Ashiya Mona | Director | S | Common Stock | 3600 | $60.16 | 295,605.0000 | 0 | 1.20% | 0.00% |
| Dec. 13, 2023 | Ashiya Mona | Director | S | Common Stock | 56200 | $58.56 | 1,126,225.0000 | 0 | 4.75% | 0.00% |
| Dec. 13, 2023 | Ashiya Mona | Director | S | Common Stock | 36400 | $58.56 | 727,907.0000 | 0 | 4.76% | 0.00% |
| Dec. 13, 2023 | Ashiya Mona | Director | S | Common Stock | 14100 | $58.56 | 281,505.0000 | 0 | 4.77% | 0.00% |
| Dec. 14, 2023 | Ashiya Mona | Director | S | Common Stock | 100 | $57.73 | 1,126,125.0000 | 0 | 0.01% | 0.00% |
| Dec. 14, 2023 | Ashiya Mona | Director | S | Common Stock | 100 | $57.73 | 727,807.0000 | 0 | 0.01% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | M | Common Stock | 21084 | $2.65 | 21,084.0000 | 0 | 9999.99% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | M | Common Stock | 5427 | $9.86 | 26,511.0000 | 0 | 25.74% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | M | Common Stock | 7000 | $13.50 | 33,511.0000 | 0 | 26.40% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | S | Common Stock | 12100 | $59.44 | 21,411.0000 | 0 | 36.11% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | S | Common Stock | 1091 | $63.73 | 20,320.0000 | 0 | 5.10% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | S | Common Stock | 16263 | $65.26 | 4,057.0000 | 0 | 80.03% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | S | Common Stock | 4057 | $66.10 | 0.0000 | 0 | 100.00% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | M | Stock Option (Right to Buy) | 21084 | $0.00 | 7,024.0000 | 0 | 75.01% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | M | Stock Option (Right to Buy) | 5427 | $0.00 | 4,216.0000 | 0 | 56.28% | 0.00% |
| Dec. 12, 2023 | White William Richard | Not found | M | Stock Option (Right to Buy) | 7000 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Dec. 12, 2023 | Bryce Joanne | Chief Financial Officer | M | Common Stock | 2500 | $2.65 | 5,000.0000 | 0 | 100.00% | 0.00% |
| Dec. 12, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 2500 | $65.22 | 2,500.0000 | 0 | 50.00% | 0.00% |
| Dec. 12, 2023 | Bryce Joanne | Chief Financial Officer | M | Stock Option (Right to Buy) | 2500 | $0.00 | 2,253.0000 | 0 | 52.60% | 0.00% |
| Dec. 12, 2023 | Bitterman Kevin | Director | S | Common Stock | 18615 | $65.10 | 1,106,182.0000 | 0 | 1.65% | 0.00% |
| Dec. 12, 2023 | Bitterman Kevin | Director | S | Common Stock | 688 | $63.78 | 1,124,797.0000 | 0 | 0.06% | 0.00% |
| Dec. 12, 2023 | Bitterman Kevin | Director | S | Common Stock | 665 | $62.90 | 1,125,485.0000 | 0 | 0.06% | 0.00% |
| Dec. 12, 2023 | Bitterman Kevin | Director | S | Common Stock | 4155 | $62.42 | 1,126,150.0000 | 0 | 0.37% | 0.00% |
| Dec. 12, 2023 | Bitterman Kevin | Director | S | Common Stock | 422 | $60.99 | 1,130,305.0000 | 0 | 0.04% | 0.00% |
| Dec. 12, 2023 | Bitterman Kevin | Director | S | Common Stock | 20823 | $59.87 | 1,130,727.0000 | 0 | 1.81% | 0.00% |
| Dec. 5, 2023 | Bryce Joanne | Chief Financial Officer | M | Stock Option (Right to Buy) | 526 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Dec. 5, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 100 | $57.06 | 2,500.0000 | 0 | 3.85% | 0.00% |
| Dec. 5, 2023 | Bryce Joanne | Chief Financial Officer | M | Stock Option (Right to Buy) | 755 | $0.00 | 752.0000 | 0 | 50.10% | 0.00% |
| Dec. 5, 2023 | Bryce Joanne | Chief Financial Officer | M | Common Stock | 526 | $1.01 | 4,286.0000 | 0 | 13.99% | 0.00% |
| Dec. 5, 2023 | Bryce Joanne | Chief Financial Officer | M | Common Stock | 755 | $1.01 | 5,041.0000 | 0 | 17.62% | 0.00% |
| Dec. 5, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 1148 | $55.29 | 3,893.0000 | 0 | 22.77% | 0.00% |
| Dec. 5, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 1293 | $56.55 | 2,600.0000 | 0 | 33.21% | 0.00% |
| Nov. 22, 2023 | Khara Rahul | General Counsel | M | Common Stock | 10000 | $14.69 | 10,000.0000 | 0 | 9999.99% | 0.00% |
| Nov. 22, 2023 | Khara Rahul | General Counsel | M | Stock Option (Right to Buy) | 10000 | $0.00 | 79,804.0000 | 0 | 11.14% | 0.00% |
| Nov. 22, 2023 | Khara Rahul | General Counsel | S | Common Stock | 9900 | $51.75 | 0.0000 | 0 | 100.00% | 0.00% |
| Nov. 22, 2023 | Khara Rahul | General Counsel | S | Common Stock | 100 | $50.34 | 9,900.0000 | 0 | 1.00% | 0.00% |
| Nov. 15, 2023 | Khara Rahul | General Counsel | M | Stock Option (Right to Buy) | 4900 | $0.00 | 89,804.0000 | 0 | 5.17% | 0.00% |
| Nov. 14, 2023 | Khara Rahul | General Counsel | S | Common Stock | 787 | $51.05 | 0.0000 | 0 | 100.00% | 0.00% |
| Nov. 14, 2023 | Khara Rahul | General Counsel | S | Common Stock | 4113 | $50.53 | 787.0000 | 0 | 83.94% | 0.00% |
| Nov. 14, 2023 | Khara Rahul | General Counsel | M | Common Stock | 4900 | $14.69 | 4,900.0000 | 0 | 9999.99% | 0.00% |
| Nov. 3, 2023 | Khara Rahul | General Counsel | M | Stock Option (Right to Buy) | 100 | $0.00 | 94,704.0000 | 0 | 0.11% | 0.00% |
| Nov. 3, 2023 | Khara Rahul | General Counsel | M | Common Stock | 100 | $14.69 | 100.0000 | 0 | 9999.99% | 0.00% |
| Nov. 3, 2023 | Khara Rahul | General Counsel | S | Common Stock | 100 | $50.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Sept. 15, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 260894 | $53.16 | 1,595,900.0000 | 0 | 14.05% | 0.00% |
| Sept. 14, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 94440 | $53.05 | 1,856,794.0000 | 0 | 4.84% | 0.00% |
| Sept. 16, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 2115 | $53.22 | 1,593,785.0000 | 0 | 0.13% | 0.00% |
| Sept. 11, 2023 | Bryce Joanne | Chief Financial Officer | M | Stock Option (Right to Buy) | 2500 | $0.00 | 76,745.0000 | 0 | 3.15% | 0.00% |
| Sept. 11, 2023 | Bryce Joanne | Chief Financial Officer | M | Common Stock | 2500 | $9.86 | 3,760.0000 | 0 | 198.41% | 0.00% |
| Sept. 1, 2023 | Bryce Joanne | Chief Financial Officer | M | Common Stock | 1000 | $2.65 | 2,260.0000 | 0 | 79.37% | 0.00% |
| Sept. 1, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 1000 | $52.99 | 1,260.0000 | 0 | 44.25% | 0.00% |
| Sept. 1, 2023 | Bryce Joanne | Chief Financial Officer | M | Stock Option (Right to Buy) | 1000 | $0.00 | 3,753.0000 | 0 | 21.04% | 0.00% |
| Aug. 21, 2023 | Savage William Jacob | Chief Medical Officer | M | Stock Option (Right to Buy) | 3000 | $0.00 | 17,326.0000 | 0 | 14.76% | 0.00% |
| Aug. 21, 2023 | Savage William Jacob | Chief Medical Officer | M | Common Stock | 3000 | $2.65 | 3,000.0000 | 0 | 9999.99% | 0.00% |
| Aug. 15, 2023 | Bitterman Kevin | Director | S | Common Stock | 72931 | $52.40 | 1,151,550.0000 | 0 | 5.96% | 0.00% |
| Aug. 14, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 75000 | $52.00 | 3,044,527.0000 | 0 | 2.40% | 0.00% |
| Aug. 15, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1839 | $53.96 | 0.0000 | 0 | 100.00% | 0.00% |
| Aug. 14, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 2000 | $54.80 | 2,944,527.0000 | 0 | 0.07% | 0.00% |
| Aug. 15, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 111069 | $52.40 | 2,833,458.0000 | 0 | 3.77% | 0.00% |
| Aug. 15, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 72931 | $52.40 | 2,833,458.0000 | 0 | 2.51% | 0.00% |
| Aug. 15, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 3708 | $52.27 | 3,964.0000 | 0 | 48.33% | 0.00% |
| Aug. 14, 2023 | Atlas Venture Fund X, L.P. | TenPercentOwner | S | Common Stock | 98000 | $53.00 | 2,946,527.0000 | 0 | 3.22% | 0.00% |
| Aug. 15, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 2125 | $53.26 | 1,839.0000 | 0 | 53.61% | 0.00% |
| Aug. 9, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1481 | $50.91 | 7,672.0000 | 0 | 16.18% | 0.00% |
| Aug. 9, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 3588 | $50.22 | 9,153.0000 | 0 | 28.16% | 0.00% |
| Aug. 9, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 3200 | $48.90 | 12,741.0000 | 0 | 20.07% | 0.00% |
| Aug. 1, 2023 | Bryce Joanne | Chief Financial Officer | M | Stock Option (Right to Buy) | 4521 | $0.00 | 1,507.0000 | 0 | 75.00% | 0.00% |
| Aug. 1, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 3067 | $49.63 | 2,714.0000 | 0 | 53.05% | 0.00% |
| Aug. 1, 2023 | Bryce Joanne | Chief Financial Officer | M | Common Stock | 4521 | $1.01 | 5,781.0000 | 0 | 358.81% | 0.00% |
| Aug. 1, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 1454 | $50.50 | 1,260.0000 | 0 | 53.57% | 0.00% |
| June 29, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 2230 | $45.49 | 22,622.0000 | 0 | 8.97% | 0.00% |
| June 28, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1564 | $50.72 | 15,941.0000 | 0 | 8.93% | 0.00% |
| June 28, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1300 | $50.00 | 17,505.0000 | 0 | 6.91% | 0.00% |
| June 28, 2023 | Savage William Jacob | Chief Medical Officer | S | Common Stock | 1520 | $49.20 | 18,805.0000 | 0 | 7.48% | 0.00% |
| June 28, 2023 | Bryce Joanne | Chief Financial Officer | M | Stock Option (Right to Buy) | 7880 | $0.00 | 526.0000 | 0 | 93.74% | 0.00% |
| June 28, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 359 | $51.23 | 1,260.0000 | 0 | 22.17% | 0.00% |
| June 28, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 4905 | $50.50 | 1,619.0000 | 0 | 75.18% | 0.00% |
| June 28, 2023 | Bryce Joanne | Chief Financial Officer | S | Common Stock | 4808 | $49.30 | 6,524.0000 | 0 | 42.43% | 0.00% |
| June 28, 2023 | Bryce Joanne | Chief Financial Officer | M | Common Stock | 7880 | $1.01 | 11,332.0000 | 0 | 228.27% | 0.00% |
| June 30, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 600 | $46.76 | 15,564.0000 | 0 | 4.01% | 0.00% |
| June 30, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 1401 | $45.45 | 16,164.0000 | 0 | 7.98% | 0.00% |
| June 30, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 2923 | $44.85 | 17,565.0000 | 0 | 14.27% | 0.00% |
| June 29, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 200 | $47.24 | 20,488.0000 | 0 | 0.97% | 0.00% |
| June 29, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 1934 | $46.51 | 20,688.0000 | 0 | 8.55% | 0.00% |
| June 29, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 736 | $44.37 | 24,852.0000 | 0 | 2.88% | 0.00% |
| June 28, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 953 | $50.80 | 25,588.0000 | 0 | 3.59% | 0.00% |
| June 28, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 1900 | $50.38 | 26,541.0000 | 0 | 6.68% | 0.00% |
| June 28, 2023 | MacDonald Brian Richard | Chief Innovation Officer | S | Common Stock | 2247 | $49.24 | 28,441.0000 | 0 | 7.32% | 0.00% |
| June 28, 2023 | Novo Holdings A/S | TenPercentOwner | S | Common Stock | 1250000 | $46.10 | 1,090,772.0000 | 0 | 53.40% | 0.00% |
| June 16, 2023 | AI DMI LLC | TenPercentOwner | P | Warrant (right to buy) | 204081 | $49.00 | 204,081.0000 | 0 | 9999.99% | 0.00% |
| June 9, 2023 | GEMAYEL GEORGES | Director | A | Stock Option (Right to Buy) | 7136 | $0.00 | 7,136.0000 | 0 | 9999.99% | 0.00% |
| June 9, 2023 | Ashiya Mona | Director | A | Stock Option (Right to Buy) | 7136 | $0.00 | 7,136.0000 | 0 | 9999.99% | 0.00% |
| June 9, 2023 | White William Richard | Director | A | Stock Option (Right to Buy) | 7136 | $0.00 | 7,136.0000 | 0 | 9999.99% | 0.00% |
| June 9, 2023 | Bitterman Kevin | Director | A | Stock Option (Right to Buy) | 7136 | $0.00 | 7,136.0000 | 0 | 9999.99% | 0.00% |
| June 9, 2023 | Nicholson Donald William | Director | A | Stock Option (Right to Buy) | 7136 | $0.00 | 7,136.0000 | 0 | 9999.99% | 0.00% |
| June 9, 2023 | Ratcliffe Liam | Director | A | Stock Option (Right to Buy) | 7136 | $0.00 | 7,136.0000 | 0 | 9999.99% | 0.00% |
| June 9, 2023 | Chin Mark | Director | A | Stock Option (Right to Buy) | 7136 | $0.00 | 7,136.0000 | 0 | 9999.99% | 0.00% |
| Feb. 15, 2023 | Ashiya Mona | Director | P | Common Stock | 37049 | $23.00 | 773,607.0000 | 0 | 5.03% | 0.00% |
| Feb. 15, 2023 | AI DMI LLC | TenPercentOwner | P | Common Stock | 434783 | $23.00 | 3,141,759.0000 | 0 | 16.06% | 0.00% |
| Feb. 15, 2023 | ORBIMED ADVISORS LLC | Director | P | Common Stock | 14329 | $23.00 | 299,205.0000 | 0 | 5.03% | 0.00% |
| Feb. 15, 2023 | ORBIMED ADVISORS LLC | Director | P | Common Stock | 37049 | $23.00 | 773,607.0000 | 0 | 5.03% | 0.00% |
| Feb. 15, 2023 | ORBIMED ADVISORS LLC | Director | P | Common Stock | 57318 | $23.00 | 1,196,825.0000 | 0 | 5.03% | 0.00% |
| Feb. 15, 2023 | Ashiya Mona | Director | P | Common Stock | 14329 | $23.00 | 299,205.0000 | 0 | 5.03% | 0.00% |
| Feb. 15, 2023 | Ashiya Mona | Director | P | Common Stock | 57318 | $23.00 | 1,196,825.0000 | 0 | 5.03% | 0.00% |
| Dec. 29, 2022 | Nicholson Donald William | Director | A | Stock Option (Right to Buy) | 7000 | $0.00 | 7,000.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Ashiya Mona | Director | A | Stock Option (Right to Buy) | 7000 | $0.00 | 7,000.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Bitterman Kevin | Director | A | Stock Option (Right to Buy) | 7000 | $0.00 | 7,000.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | ORBIMED ADVISORS LLC | Director | J | Common Stock | 1139507 | $0.00 | 1,139,507.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | ORBIMED ADVISORS LLC | Director | J | Common Stock | 153936 | $0.00 | 736,558.0000 | 0 | 26.42% | 0.00% |
| Dec. 29, 2022 | ORBIMED ADVISORS LLC | Director | J | Common Stock | 582622 | $0.00 | 582,622.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | ORBIMED ADVISORS LLC | Director | J | Common Stock | 284876 | $0.00 | 284,876.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Atlas Venture Fund X, L.P. | TenPercentOwner | J | Common Stock | 882224 | $0.00 | 3,192,459.0000 | 0 | 38.19% | 0.00% |
| Dec. 29, 2022 | Atlas Venture Fund X, L.P. | TenPercentOwner | J | Common Stock | 1835799 | $0.00 | 3,192,459.0000 | 0 | 135.32% | 0.00% |
| Dec. 29, 2022 | Bryce Joanne | Chief Financial Officer | A | Stock Option (Right to Buy) | 33847 | $0.00 | 33,847.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Savage William Jacob | Chief Medical Officer | A | Stock Option (Right to Buy) | 38924 | $0.00 | 38,924.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Quisel John D | Chief Executive Officer | A | Stock Option (Right to Buy) | 132002 | $0.00 | 132,002.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Backstrom Jay T. | Director | A | Stock Option (Right to Buy) | 7000 | $0.00 | 7,000.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | White William Richard | Director | A | Stock Option (Right to Buy) | 7000 | $0.00 | 7,000.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Ratcliffe Liam | Director | A | Stock Option (Right to Buy) | 7000 | $0.00 | 7,000.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Yu Jonathan Yen-Wen | Chief Business Officer | A | Stock Option (Right to Buy) | 33847 | $0.00 | 33,847.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Khara Rahul | General Counsel | A | Stock Option (Right to Buy) | 28770 | $0.00 | 28,770.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | Chin Mark | Director | A | Stock Option (Right to Buy) | 7000 | $0.00 | 7,000.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | MacDonald Brian Richard | Chief Innovation Officer | A | Stock Option (Right to Buy) | 33847 | $0.00 | 33,847.0000 | 0 | 9999.99% | 0.00% |
| Dec. 29, 2022 | GEMAYEL GEORGES | Director | A | Stock Option (Right to Buy) | 7000 | $0.00 | 7,000.0000 | 0 | 9999.99% | 0.00% |