SEC Insider Transactions from ORBIMED ADVISORS LLC.

Last updated: 2026-03-14 11:47 UTC | Total transactions: 229

ORBIMED ADVISORS LLC has filed 229 insider transactions across 24 companies since December 2022.

Most recent transaction: a sale of 1890 shares of Sionna Therapeutics, Inc. ($SION) on February 02, 2026.

Activity breakdown: 40 open-market purchases and 151 sales.

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Transaction Date Company Ticker Insider Name Title Transaction Type Security Shares Price Shares Owned Following Total Shares Outstanding % of Owned % of Outstanding
Feb. 2, 2026 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 1890 $44.57 3,559,765.0000 44,628,788 0.05% 0.00%
Feb. 3, 2026 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 29063 $44.58 3,530,702.0000 44,628,788 0.82% 0.07%
Dec. 24, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 33356 $44.55 3,561,655.0000 44,628,788 0.93% 0.07%
Dec. 18, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 100 $44.49 3,595,886.0000 44,628,788 0.00% 0.00%
Dec. 17, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 900 $44.50 3,595,986.0000 44,628,788 0.03% 0.00%
Dec. 19, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 875 $44.49 3,595,011.0000 44,628,788 0.02% 0.00%
Nov. 21, 2025 Keros Therapeutics, Inc. $KROS ORBIMED ADVISORS LLC Director D Common Stock 74465 $17.75 45,057.0000 41,202,371 62.30% 0.18%
Nov. 21, 2025 Keros Therapeutics, Inc. $KROS ORBIMED ADVISORS LLC Director D Common Stock 140057 $17.75 759,155.0000 41,202,371 15.58% 0.34%
Nov. 24, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 94583 $44.54 3,610,376.0000 44,628,788 2.55% 0.21%
Nov. 26, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 1600 $44.49 3,596,886.0000 44,628,788 0.04% 0.00%
Nov. 25, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director S Common Stock 11890 $44.60 3,598,486.0000 44,628,788 0.33% 0.03%
Oct. 23, 2025 PMV Pharmaceuticals, Inc. $PMVP ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 1000000 $1.52 4,975,291.0000 51,933,604 16.74% 1.93%
Oct. 8, 2025 Adicet Bio, Inc. $ACET ORBIMED ADVISORS LLC TenPercentOwner P Common Stock 3500000 $1.00 7,420,781.0000 82,685,750 89.27% 4.23%
Oct. 8, 2025 Adicet Bio, Inc. $ACET ORBIMED ADVISORS LLC TenPercentOwner P Common Stock 1500000 $1.00 11,956,886.0000 82,685,750 14.34% 1.81%
Sept. 10, 2025 PMV Pharmaceuticals, Inc. $PMVP ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 500000 $1.80 5,975,291.0000 51,933,604 7.72% 0.96%
Aug. 25, 2025 Shattuck Labs, Inc. $STTK ORBIMED ADVISORS LLC Director P Common Warrants (right to buy) 3073298 $0.00 3,073,298.0000 50,758,290 9999.99% 6.05%
Aug. 25, 2025 Shattuck Labs, Inc. $STTK ORBIMED ADVISORS LLC Director P Common Warrants (right to buy) 15366490 $0.00 15,366,490.0000 50,758,290 9999.99% 30.27%
Aug. 25, 2025 Shattuck Labs, Inc. $STTK ORBIMED ADVISORS LLC Director P Common Stock 1051021 $0.87 1,051,021.0000 50,758,290 9999.99% 2.07%
Aug. 25, 2025 Shattuck Labs, Inc. $STTK ORBIMED ADVISORS LLC Director P Pre-Funded Warrants (right to buy) 10111384 $0.00 10,111,384.0000 50,758,290 9999.99% 19.92%
Aug. 25, 2025 Shattuck Labs, Inc. $STTK ORBIMED ADVISORS LLC Director P Pre-Funded Warrants (right to buy) 2022277 $0.00 2,022,277.0000 50,758,290 9999.99% 3.98%
Aug. 25, 2025 Shattuck Labs, Inc. $STTK ORBIMED ADVISORS LLC Director P Common Stock 5255106 $0.87 5,255,106.0000 50,758,290 9999.99% 10.35%
Aug. 8, 2025 Turnstone Biologics Corp. $TSBX ORBIMED ADVISORS LLC Director U Common Stock 3099265 $0.00 0.0000 23,138,896 100.00% 13.39%
July 25, 2025 ImageneBio, Inc. $IMA ORBIMED ADVISORS LLC Director A Common Stock 83611 $2.49 295,469.0000 48,258,111 39.47% 0.17%
June 27, 2025 Corvus Pharmaceuticals, Inc. $CRVS ORBIMED ADVISORS LLC Director X Common Stock 1397684 $3.50 8,341,338.0000 75,152,514 20.13% 1.86%
June 27, 2025 Corvus Pharmaceuticals, Inc. $CRVS ORBIMED ADVISORS LLC Director X Common Warrants (right to buy) 1397684 $0.00 0.0000 75,152,514 100.00% 1.86%
June 27, 2025 Corvus Pharmaceuticals, Inc. $CRVS ORBIMED ADVISORS LLC Director S Common Stock 1176332 $4.16 7,165,006.0000 75,152,514 14.10% 1.57%
June 24, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 231600 $0.35 6,418,400.0000 62,109,991 3.48% 0.37%
June 25, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 138800 $0.33 6,279,600.0000 62,109,991 2.16% 0.22%
June 26, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 213257 $0.33 6,066,343.0000 62,109,991 3.40% 0.34%
May 14, 2025 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 134136 $15.83 3,272,199.0000 32,560,130 3.94% 0.41%
May 14, 2025 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 34000 $15.94 3,238,199.0000 32,560,130 1.04% 0.10%
April 23, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 89328 $0.34 6,718,195.0000 62,109,991 1.31% 0.14%
April 22, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 78049 $0.34 6,807,523.0000 62,109,991 1.13% 0.13%
April 24, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 68195 $0.32 6,650,000.0000 62,109,991 1.02% 0.11%
April 17, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 77090 $0.33 6,885,572.0000 62,109,991 1.11% 0.12%
April 16, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 61638 $0.33 6,962,662.0000 62,109,991 0.88% 0.10%
April 15, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 10326 $0.38 7,024,300.0000 62,109,991 0.15% 0.02%
April 10, 2025 Xtant Medical Holdings, Inc. $XTNT ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 17109618 $0.42 0.0000 133,665,075 100.00% 12.80%
April 10, 2025 Xtant Medical Holdings, Inc. $XTNT ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 56004974 $0.42 0.0000 133,665,075 100.00% 41.90%
April 9, 2025 Compass Therapeutics, Inc. $CMPX ORBIMED ADVISORS LLC Director S Common Stock 3571428 $1.59 15,219,994.0000 138,282,498 19.01% 2.58%
April 3, 2025 Edgewise Therapeutics, Inc. $EWTX ORBIMED ADVISORS LLC Director P Common Stock 124193 $20.13 443,792.0000 95,130,053 38.86% 0.13%
April 3, 2025 Edgewise Therapeutics, Inc. $EWTX ORBIMED ADVISORS LLC Director P Common Stock 372578 $20.13 14,809,075.0000 95,130,053 2.58% 0.39%
March 24, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 1956 $54.11 482,308.0000 34,569,042 0.40% 0.01%
March 24, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 3026 $54.11 746,171.0000 34,569,042 0.40% 0.01%
March 24, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 756 $54.11 186,541.0000 34,569,042 0.40% 0.00%
March 21, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 5279 $54.00 749,197.0000 34,569,042 0.70% 0.02%
March 21, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 3412 $54.00 484,264.0000 34,569,042 0.70% 0.01%
March 20, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 1457 $54.01 754,476.0000 34,569,042 0.19% 0.00%
March 20, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 364 $54.01 188,617.0000 34,569,042 0.19% 0.00%
March 19, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 5228 $54.02 188,981.0000 34,569,042 2.69% 0.02%
March 19, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 20911 $54.02 755,933.0000 34,569,042 2.69% 0.06%
March 19, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 13517 $54.02 488,617.0000 34,569,042 2.69% 0.04%
March 21, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 1320 $54.00 187,297.0000 34,569,042 0.70% 0.00%
March 20, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 941 $54.01 487,676.0000 34,569,042 0.19% 0.00%
March 12, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 233 $55.05 204,942.0000 34,569,042 0.11% 0.00%
March 10, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 68766 $54.29 539,845.0000 34,569,042 11.30% 0.20%
March 10, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 106384 $54.29 835,185.0000 34,569,042 11.30% 0.31%
March 10, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 26596 $54.29 208,795.0000 34,569,042 11.30% 0.08%
March 10, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 136 $55.01 539,709.0000 34,569,042 0.03% 0.00%
March 10, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 211 $55.01 834,974.0000 34,569,042 0.03% 0.00%
March 10, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 53 $55.01 208,742.0000 34,569,042 0.03% 0.00%
March 11, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 9222 $54.01 530,487.0000 34,569,042 1.71% 0.03%
March 11, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 14267 $54.01 820,707.0000 34,569,042 1.71% 0.04%
March 11, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 3567 $54.01 205,175.0000 34,569,042 1.71% 0.01%
March 12, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 603 $55.05 529,884.0000 34,569,042 0.11% 0.00%
March 12, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 933 $55.05 819,774.0000 34,569,042 0.11% 0.00%
March 12, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 27750 $54.44 502,134.0000 34,569,042 5.24% 0.08%
March 12, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 42930 $54.44 776,844.0000 34,569,042 5.24% 0.12%
March 12, 2025 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 10733 $54.44 194,209.0000 34,569,042 5.24% 0.03%
Feb. 14, 2025 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Director P Common Stock 29540 $9.85 3,205,930.0000 0 0.93% 0.00%
Feb. 14, 2025 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Director P Common Stock 17962 $9.90 3,176,390.0000 0 0.57% 0.00%
Feb. 18, 2025 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Director P Common Stock 49070 $10.84 3,255,000.0000 0 1.53% 0.00%
Feb. 18, 2025 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Director P Common Stock 94100 $10.84 747,887.0000 0 14.39% 0.00%
Feb. 10, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director C Common Stock 3154959 $0.00 3,154,959.0000 0 9999.99% 0.00%
Feb. 10, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director C Series C convertible preferred stock 2048760 $0.00 0.0000 0 100.00% 0.00%
Feb. 10, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director C Series B convertible preferred stock 2560951 $0.00 0.0000 0 100.00% 0.00%
Feb. 10, 2025 Sionna Therapeutics, Inc. $SION ORBIMED ADVISORS LLC Director P Common Stock 550000 $18.00 3,704,959.0000 0 17.43% 0.00%
Dec. 29, 2024 Traws Pharma, Inc. $TRAW ORBIMED ADVISORS LLC TenPercentOwner P Pre-Funded Warrant (right to buy) 96348 $0.00 96,348.0000 961,530 9999.99% 10.02%
Dec. 29, 2024 Traws Pharma, Inc. $TRAW ORBIMED ADVISORS LLC TenPercentOwner P Series A Warrant (right to buy) 96348 $0.00 96,348.0000 961,530 9999.99% 10.02%
Jan. 10, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 126209 $0.66 7,131,636.0000 3,078,665 1.74% 4.10%
Jan. 13, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 17986 $0.64 7,113,650.0000 3,078,665 0.25% 0.58%
Jan. 14, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 79024 $0.60 7,034,626.0000 3,078,665 1.11% 2.57%
Jan. 8, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 75007 $0.68 7,257,845.0000 3,078,665 1.02% 2.44%
Jan. 6, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 19481 $0.77 7,385,388.0000 3,078,665 0.26% 0.63%
Jan. 7, 2025 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 52536 $0.71 7,332,852.0000 3,078,665 0.71% 1.71%
Dec. 20, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 230321 $0.60 7,404,869.0000 3,146,582 3.02% 7.32%
Dec. 10, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 8015 $0.80 7,635,270.0000 3,146,582 0.10% 0.25%
Dec. 11, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 80 $0.80 7,635,190.0000 3,146,582 0.00% 0.00%
Dec. 9, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 54181 $0.84 7,643,285.0000 3,146,582 0.70% 1.72%
Dec. 4, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 76200 $0.79 7,718,369.0000 3,146,582 0.98% 2.42%
Dec. 6, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 20903 $0.82 7,697,466.0000 3,146,582 0.27% 0.66%
Oct. 15, 2024 Upstream Bio, Inc. $UPB ORBIMED ADVISORS LLC Director C Series B redeemable convertible preferred stock 789833 $0.00 0.0000 0 100.00% 0.00%
Oct. 15, 2024 Upstream Bio, Inc. $UPB ORBIMED ADVISORS LLC Director P Common Stock 660000 $17.00 4,554,873.0000 0 16.95% 0.00%
Oct. 15, 2024 Upstream Bio, Inc. $UPB ORBIMED ADVISORS LLC Director C Series A redeemable convertible preferred stock 524500 $0.00 0.0000 0 100.00% 0.00%
Oct. 15, 2024 Upstream Bio, Inc. $UPB ORBIMED ADVISORS LLC Director C Series A redeemable convertible preferred stock 2098000 $0.00 0.0000 0 100.00% 0.00%
Oct. 15, 2024 Upstream Bio, Inc. $UPB ORBIMED ADVISORS LLC Director C Series B redeemable convertible preferred stock 197456 $0.00 0.0000 0 100.00% 0.00%
Oct. 15, 2024 Upstream Bio, Inc. $UPB ORBIMED ADVISORS LLC Director C Common Stock 721956 $0.00 973,716.0000 0 286.76% 0.00%
Oct. 15, 2024 Upstream Bio, Inc. $UPB ORBIMED ADVISORS LLC Director P Common Stock 165000 $17.00 1,138,716.0000 0 16.95% 0.00%
Oct. 15, 2024 Upstream Bio, Inc. $UPB ORBIMED ADVISORS LLC Director C Common Stock 2887833 $0.00 3,894,873.0000 0 286.76% 0.00%
Sept. 19, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 39300 $0.71 7,794,569.0000 3,142,537 0.50% 1.25%
Sept. 18, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 25631 $0.73 7,833,869.0000 3,142,537 0.33% 0.82%
Sept. 17, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 111400 $0.73 7,859,500.0000 3,142,537 1.40% 3.54%
Sept. 16, 2024 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 63100 $0.74 7,970,900.0000 3,142,537 0.79% 2.01%
Sept. 16, 2024 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Not found P Common Stock 250000 $16.00 3,812,215.0000 0 7.02% 0.00%
Sept. 16, 2024 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Not found C Series A Convertible Preferred Stock 12372634 $0.00 0.0000 0 100.00% 0.00%
Sept. 16, 2024 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Not found C Series B Convertible Preferred Stock 19587284 $0.00 0.0000 0 100.00% 0.00%
Sept. 16, 2024 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Not found C Series C Convertible Preferred Stock 4854368 $0.00 0.0000 0 100.00% 0.00%
Sept. 16, 2024 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Not found C Common Stock 2658428 $0.00 3,312,215.0000 0 406.62% 0.00%
Sept. 16, 2024 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Not found C Common Stock 403787 $0.00 3,562,215.0000 0 12.78% 0.00%
Sept. 16, 2024 MBX Biosciences, Inc. $MBX ORBIMED ADVISORS LLC Not found P Common Stock 500000 $16.00 3,812,215.0000 0 15.10% 0.00%
Aug. 26, 2024 ARS Pharmaceuticals, Inc. $SPRY ORBIMED ADVISORS LLC Director S Common Stock 83695 $13.00 8,288,510.0000 95,215,322 1.00% 0.09%
Aug. 23, 2024 ARS Pharmaceuticals, Inc. $SPRY ORBIMED ADVISORS LLC Director S Common Stock 69500 $13.03 8,372,205.0000 95,215,322 0.82% 0.07%
Aug. 22, 2024 ARS Pharmaceuticals, Inc. $SPRY ORBIMED ADVISORS LLC Director S Common Stock 391482 $12.94 8,441,705.0000 95,215,322 4.43% 0.41%
Aug. 21, 2024 ARS Pharmaceuticals, Inc. $SPRY ORBIMED ADVISORS LLC Director S Common Stock 13300 $14.61 8,833,187.0000 95,215,322 0.15% 0.01%
Aug. 21, 2024 ARS Pharmaceuticals, Inc. $SPRY ORBIMED ADVISORS LLC Director S Common Stock 394400 $13.52 8,846,487.0000 95,215,322 4.27% 0.41%
Aug. 13, 2024 Keros Therapeutics, Inc. $KROS ORBIMED ADVISORS LLC Director S Common Stock 29400 $44.01 119,522.0000 29,447,119 19.74% 0.10%
Aug. 13, 2024 scPharmaceuticals Inc. $SCPH ORBIMED ADVISORS LLC TenPercentOwner P Common Stock 21658 $4.00 252,858.0000 38,984,745 9.37% 0.06%
Aug. 13, 2024 scPharmaceuticals Inc. $SCPH ORBIMED ADVISORS LLC TenPercentOwner P Common Stock 478342 $4.00 5,806,670.0000 38,984,745 8.98% 1.23%
Aug. 13, 2024 Keros Therapeutics, Inc. $KROS ORBIMED ADVISORS LLC Director S Common Stock 220600 $44.01 899,212.0000 29,447,119 19.70% 0.75%
July 16, 2024 Terns Pharmaceuticals, Inc. $TERN ORBIMED ADVISORS LLC Director S Common Stock 556 $10.00 1,967,924.0000 71,259,239 0.03% 0.00%
July 15, 2024 Terns Pharmaceuticals, Inc. $TERN ORBIMED ADVISORS LLC Director S Common Stock 6142 $10.00 756,258.0000 71,259,239 0.81% 0.01%
July 15, 2024 Terns Pharmaceuticals, Inc. $TERN ORBIMED ADVISORS LLC Director S Common Stock 5401 $10.00 1,968,480.0000 71,259,239 0.27% 0.01%
July 15, 2024 Terns Pharmaceuticals, Inc. $TERN ORBIMED ADVISORS LLC Director S Common Stock 39433 $10.00 4,843,421.0000 71,259,239 0.81% 0.06%
July 16, 2024 Terns Pharmaceuticals, Inc. $TERN ORBIMED ADVISORS LLC Director S Common Stock 4009 $10.00 4,839,412.0000 71,259,239 0.08% 0.01%
July 16, 2024 Terns Pharmaceuticals, Inc. $TERN ORBIMED ADVISORS LLC Director S Common Stock 623 $10.00 755,635.0000 71,259,239 0.08% 0.00%
June 28, 2024 TELA Bio, Inc. $TELA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 378000 $4.74 2,457,542.0000 24,579,386 13.33% 1.54%
July 2, 2024 TELA Bio, Inc. $TELA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 36600 $4.54 2,407,242.0000 24,663,234 1.50% 0.15%
July 1, 2024 TELA Bio, Inc. $TELA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 13700 $4.68 2,443,842.0000 24,663,234 0.56% 0.06%
June 17, 2024 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director P Common Stock 43944 $36.00 941,569.0000 0 4.90% 0.00%
June 17, 2024 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director P Common Stock 28404 $36.00 608,611.0000 0 4.90% 0.00%
June 17, 2024 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director P Common Stock 10986 $36.00 235,391.0000 0 4.90% 0.00%
May 16, 2024 Enliven Therapeutics, Inc. $ELVN ORBIMED ADVISORS LLC Director S Common Stock 1000000 $22.14 7,663,349.0000 35,546,215 11.54% 2.81%
May 16, 2024 Enliven Therapeutics, Inc. $ELVN ORBIMED ADVISORS LLC Director S Common Stock 33300 $22.14 254,814.0000 35,546,215 11.56% 0.09%
May 6, 2024 Corvus Pharmaceuticals, Inc. $CRVS ORBIMED ADVISORS LLC Director P Pre-Funded Warrants (right to buy) 1444085 $1.73 1,444,085.0000 49,038,582 9999.99% 2.94%
May 6, 2024 Corvus Pharmaceuticals, Inc. $CRVS ORBIMED ADVISORS LLC Director P Common Warrants (right to buy) 1397684 $0.00 1,397,684.0000 49,038,582 9999.99% 2.85%
May 2, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 8842 $14.01 3,411,009.0000 0 0.26% 0.00%
May 3, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 4674 $14.03 3,406,335.0000 0 0.14% 0.00%
May 1, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 15690 $14.02 3,419,851.0000 0 0.46% 0.00%
April 24, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 1781 $14.06 3,435,541.0000 0 0.05% 0.00%
April 19, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 18253 $14.02 3,483,722.0000 0 0.52% 0.00%
April 23, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 21791 $14.29 3,437,322.0000 0 0.63% 0.00%
April 22, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 24609 $14.05 3,459,113.0000 0 0.71% 0.00%
April 17, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 300 $14.15 3,504,598.0000 0 0.01% 0.00%
April 16, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 14069 $14.01 3,504,898.0000 0 0.40% 0.00%
April 18, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 2623 $14.06 3,501,975.0000 0 0.07% 0.00%
April 12, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 23101 $14.42 3,518,967.0000 0 0.65% 0.00%
April 11, 2024 NeuroPace Inc $NPCE ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 461899 $14.49 3,542,068.0000 0 11.54% 0.00%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director C Common Stock 821827 $0.00 821,827.0000 2,140,951 9999.99% 38.39%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director P Common Stock 222222 $18.00 1,513,664.0000 2,140,951 17.21% 10.38%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director P Common Stock 222222 $18.00 1,513,664.0000 2,140,951 17.21% 10.38%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director C Common Stock 821827 $0.00 821,827.0000 2,140,951 9999.99% 38.39%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director C Series A Preferred Stock 821827 $0.00 0.0000 2,140,951 100.00% 38.39%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director C Series A Preferred Stock 821827 $0.00 0.0000 2,140,951 100.00% 38.39%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director C Common Stock 469615 $0.00 1,291,442.0000 2,140,951 57.14% 21.94%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director C Common Stock 469615 $0.00 1,291,442.0000 2,140,951 57.14% 21.94%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director C Series B Preferred Stock 469615 $0.00 0.0000 2,140,951 100.00% 21.94%
Jan. 30, 2024 ArriVent BioPharma, Inc. $AVBP ORBIMED ADVISORS LLC Director C Series B Preferred Stock 469615 $0.00 0.0000 2,140,951 100.00% 21.94%
Jan. 25, 2024 Adicet Bio, Inc. $ACET ORBIMED ADVISORS LLC Not found P Common Stock 1841100 $2.40 9,200,901.0000 0 25.02% 0.00%
Jan. 25, 2024 Adicet Bio, Inc. $ACET ORBIMED ADVISORS LLC Not found P Common Stock 242200 $2.40 2,664,796.0000 0 10.00% 0.00%
Jan. 25, 2024 Adicet Bio, Inc. $ACET ORBIMED ADVISORS LLC Not found P Common Stock 1041700 $2.40 2,930,527.0000 0 55.15% 0.00%
Jan. 23, 2024 Edgewise Therapeutics, Inc. $EWTX ORBIMED ADVISORS LLC Director P Common Stock 454545 $11.00 14,756,096.0000 63,723,600 3.18% 0.71%
Dec. 18, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director M Common Stock 1724 $38.00 1,703,961.0000 0 0.10% 0.00%
Dec. 18, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 1724 $59.24 1,702,237.0000 0 0.10% 0.00%
Dec. 18, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director M Stock Options (Right to Buy) 1724 $0.00 0.0000 0 100.00% 0.00%
Dec. 14, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 57100 $56.75 224,405.0000 0 20.28% 0.00%
Dec. 14, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 228500 $56.75 897,625.0000 0 20.29% 0.00%
Dec. 14, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 147600 $56.75 580,207.0000 0 20.28% 0.00%
Dec. 12, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 14400 $60.16 1,182,425.0000 0 1.20% 0.00%
Dec. 12, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 9300 $60.16 764,307.0000 0 1.20% 0.00%
Dec. 12, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 3600 $60.16 295,605.0000 0 1.20% 0.00%
Dec. 13, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 56200 $58.56 1,126,225.0000 0 4.75% 0.00%
Dec. 13, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 14100 $58.56 281,505.0000 0 4.77% 0.00%
Dec. 13, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 36400 $58.56 727,907.0000 0 4.76% 0.00%
Dec. 14, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 100 $57.73 727,807.0000 0 0.01% 0.00%
Dec. 14, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director S Common Stock 100 $57.73 1,126,125.0000 0 0.01% 0.00%
Nov. 22, 2023 PMV Pharmaceuticals, Inc. $PMVP ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 87786 $2.23 6,475,291.0000 0 1.34% 0.00%
Aug. 29, 2023 ARS Pharmaceuticals, Inc. $SPRY ORBIMED ADVISORS LLC Director P Common Stock 500000 $6.20 9,240,887.0000 0 5.72% 0.00%
Aug. 15, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 535534 $0.75 1,510,375.0000 0 26.18% 0.00%
Aug. 15, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 248819 $0.75 631,048.0000 0 28.28% 0.00%
Aug. 15, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 38327 $0.75 97,204.0000 0 28.28% 0.00%
July 31, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 26622 $3.00 135,531.0000 0 16.42% 0.00%
July 31, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 153078 $3.00 2,105,909.0000 0 6.78% 0.00%
July 31, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 29700 $3.00 879,867.0000 0 3.27% 0.00%
July 25, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 4700 $2.92 909,567.0000 0 0.51% 0.00%
July 25, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 26700 $2.92 2,258,987.0000 0 1.17% 0.00%
July 25, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 7800 $2.92 162,153.0000 0 4.59% 0.00%
July 13, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 52800 $2.40 914,267.0000 0 5.46% 0.00%
July 13, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 132100 $2.40 2,285,687.0000 0 5.46% 0.00%
July 13, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 9800 $2.40 169,953.0000 0 5.45% 0.00%
June 28, 2023 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner P Common Stock 575195 $0.84 8,034,000.0000 54,618,799 7.71% 1.05%
June 27, 2023 Passage BIO, Inc. $PASG ORBIMED ADVISORS LLC TenPercentOwner P Common Stock 617382 $0.84 7,458,805.0000 54,618,799 9.02% 1.13%
May 17, 2023 Enliven Therapeutics, Inc. $ELVN ORBIMED ADVISORS LLC Director M Stock Options (Right to Buy) 2125 $0.00 0.0000 0 100.00% 0.00%
May 17, 2023 Enliven Therapeutics, Inc. $ELVN ORBIMED ADVISORS LLC Director M Common Stock 2125 $4.28 8,951,463.0000 0 0.02% 0.00%
April 19, 2023 TELA Bio, Inc. $TELA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 136000 $9.30 2,891,542.0000 19,185,621 4.49% 0.71%
April 21, 2023 TELA Bio, Inc. $TELA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 27700 $9.41 2,835,542.0000 19,185,621 0.97% 0.14%
April 20, 2023 TELA Bio, Inc. $TELA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 28300 $9.43 2,863,242.0000 19,185,621 0.98% 0.15%
April 17, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 3551 $1.97 967,067.0000 0 0.37% 0.00%
April 13, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 703 $1.82 182,504.0000 0 0.38% 0.00%
April 13, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 3784 $1.82 981,863.0000 0 0.38% 0.00%
April 13, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 9459 $1.82 2,454,775.0000 0 0.38% 0.00%
April 14, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 2091 $1.86 180,413.0000 0 1.15% 0.00%
April 14, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 11245 $1.86 970,618.0000 0 1.15% 0.00%
April 14, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 28110 $1.86 2,426,665.0000 0 1.15% 0.00%
April 17, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 660 $1.97 179,753.0000 0 0.37% 0.00%
April 17, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 8878 $1.97 2,417,787.0000 0 0.37% 0.00%
April 12, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 641 $1.81 985,647.0000 0 0.06% 0.00%
April 12, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 1603 $1.81 2,464,234.0000 0 0.07% 0.00%
April 10, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 2584 $1.79 185,910.0000 0 1.37% 0.00%
April 10, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 13899 $1.79 1,000,187.0000 0 1.37% 0.00%
April 10, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 34745 $1.79 2,500,582.0000 0 1.37% 0.00%
April 11, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 703 $1.82 183,326.0000 0 0.38% 0.00%
April 11, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 3784 $1.82 986,288.0000 0 0.38% 0.00%
April 11, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 9459 $1.82 2,465,837.0000 0 0.38% 0.00%
April 12, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 119 $1.81 183,207.0000 0 0.06% 0.00%
April 6, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 487 $2.00 186,613.0000 0 0.26% 0.00%
April 6, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 6558 $2.00 2,510,041.0000 0 0.26% 0.00%
April 6, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 2620 $2.00 1,003,971.0000 0 0.26% 0.00%
April 5, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 4687 $2.18 187,100.0000 0 2.44% 0.00%
April 5, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 25220 $2.18 1,006,591.0000 0 2.44% 0.00%
April 5, 2023 Damora Therapeutics, Inc. $DMRA ORBIMED ADVISORS LLC TenPercentOwner S Common Stock 63058 $2.18 2,516,599.0000 0 2.44% 0.00%
Feb. 23, 2023 Enliven Therapeutics, Inc. $ELVN ORBIMED ADVISORS LLC Director A Common Stock 288114 $0.00 288,114.0000 0 9999.99% 0.00%
Feb. 23, 2023 Enliven Therapeutics, Inc. $ELVN ORBIMED ADVISORS LLC Director A Common Stock 7611458 $0.00 8,661,225.0000 0 725.06% 0.00%
Feb. 15, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director P Common Stock 14329 $23.00 299,205.0000 0 5.03% 0.00%
Feb. 15, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director P Common Stock 37049 $23.00 773,607.0000 0 5.03% 0.00%
Feb. 15, 2023 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director P Common Stock 57318 $23.00 1,196,825.0000 0 5.03% 0.00%
Dec. 29, 2022 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director J Common Stock 1139507 $0.00 1,139,507.0000 0 9999.99% 0.00%
Dec. 29, 2022 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director J Common Stock 582622 $0.00 582,622.0000 0 9999.99% 0.00%
Dec. 29, 2022 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director J Common Stock 284876 $0.00 284,876.0000 0 9999.99% 0.00%
Dec. 29, 2022 Disc Medicine, Inc. $IRON ORBIMED ADVISORS LLC Director J Common Stock 153936 $0.00 736,558.0000 0 26.42% 0.00%