In the last 12 months, insiders at Sionna Therapeutics, Inc. ($SION) filed 232 transactions with the SEC: 8 open-market purchases totaling $63,410,400 and 135 sales totaling $78,369,899. Net insider sentiment: net selling.
Sionna Therapeutics, Inc. operates in the Pharmaceutical preparations industry (Life sciences sector).
Most Active Insiders
- RA CAPITAL MANAGEMENT, L.P. (Not found) — 61 transactions totaling $41,713,466
- TPG GP A, LLC (TenPercentOwner) — 8 transactions totaling $31,200,400
- Booth Bruce (Not found) — 58 transactions totaling $23,165,832
- ORBIMED ADVISORS LLC (Director) — 13 transactions totaling $17,663,508
- Thompson Peter A. (Not found) — 4 transactions totaling $9,900,000
View all SEC Filings for Sionna Therapeutics, Inc. (SION).
Set Up your own filters →Recent Insider Transactions
| Transaction Date | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|
| March 5, 2026 | Fitzpatrick Jennifer | Chief Legal Officer | M | Non-Qualified Stock Option (right to buy) | 10250 | $0.00 | 50,935.0000 | 44,628,788 | 16.75% | 0.02% |
| March 5, 2026 | Fitzpatrick Jennifer | Chief Legal Officer | M | Common Stock | 10250 | $6.11 | 10,250.0000 | 44,628,788 | 9999.99% | 0.02% |
| March 5, 2026 | Fitzpatrick Jennifer | Chief Legal Officer | S | Common Stock | 10250 | $33.86 | 0.0000 | 44,628,788 | 100.00% | 0.02% |
| Feb. 3, 2026 | Thompson Peter A. | Director | S | Common Stock | 29063 | $44.58 | 3,530,702.0000 | 44,628,788 | 0.82% | 0.07% |
| Feb. 3, 2026 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 29063 | $44.58 | 3,530,702.0000 | 44,628,788 | 0.82% | 0.07% |
| Feb. 2, 2026 | Thompson Peter A. | Director | S | Common Stock | 1890 | $44.57 | 3,559,765.0000 | 44,628,788 | 0.05% | 0.00% |
| Feb. 2, 2026 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 1890 | $44.57 | 3,559,765.0000 | 44,628,788 | 0.05% | 0.00% |
| Jan. 22, 2026 | TPG GP A, LLC | TenPercentOwner | S | Common Stock | 250000 | $40.00 | 6,494,962.0000 | 44,628,788 | 3.71% | 0.56% |
| Jan. 2, 2026 | Fitzpatrick Jennifer | Chief Legal Officer | A | Non-Qualified Stock Option (right to buy) | 103140 | $0.00 | 103,140.0000 | 44,628,788 | 9999.99% | 0.23% |
| Jan. 2, 2026 | Ridloff Elena | CFO | A | Non-Qualified Stock Option (right to buy) | 165440 | $0.00 | 165,440.0000 | 44,628,788 | 9999.99% | 0.37% |
| Jan. 2, 2026 | Beer Caroline Stark | Chief Business Officer | A | Non-Qualified Stock Option (right to buy) | 139340 | $0.00 | 139,340.0000 | 44,628,788 | 9999.99% | 0.31% |
| Jan. 2, 2026 | Cloonan Michael | President & CEO | A | Non-Qualified Stock Option (right to buy) | 436100 | $0.00 | 436,100.0000 | 44,628,788 | 9999.99% | 0.98% |
| Jan. 2, 2026 | McKee Charlotte | Chief Medical Officer | A | Non-Qualified Stock Option (right to buy) | 155700 | $0.00 | 155,700.0000 | 44,628,788 | 9999.99% | 0.35% |
| Dec. 24, 2025 | Thompson Peter A. | Director | S | Common Stock | 33356 | $44.55 | 3,561,655.0000 | 44,628,788 | 0.93% | 0.07% |
| Dec. 24, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 33356 | $44.55 | 3,561,655.0000 | 44,628,788 | 0.93% | 0.07% |
| Dec. 19, 2025 | Thompson Peter A. | Director | S | Common Stock | 875 | $44.49 | 3,595,011.0000 | 44,628,788 | 0.02% | 0.00% |
| Dec. 18, 2025 | Thompson Peter A. | Director | S | Common Stock | 100 | $44.49 | 3,595,886.0000 | 44,628,788 | 0.00% | 0.00% |
| Dec. 17, 2025 | Thompson Peter A. | Director | S | Common Stock | 900 | $44.50 | 3,595,986.0000 | 44,628,788 | 0.03% | 0.00% |
| Dec. 19, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 875 | $44.49 | 3,595,011.0000 | 44,628,788 | 0.02% | 0.00% |
| Dec. 18, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 100 | $44.49 | 3,595,886.0000 | 44,628,788 | 0.00% | 0.00% |
| Dec. 17, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 900 | $44.50 | 3,595,986.0000 | 44,628,788 | 0.03% | 0.00% |
| Dec. 5, 2025 | Fitzpatrick Jennifer | Chief Legal Officer | M | Common Stock | 10250 | $6.11 | 10,250.0000 | 44,628,788 | 9999.99% | 0.02% |
| Dec. 5, 2025 | Fitzpatrick Jennifer | Chief Legal Officer | M | Non-Qualified Stock Option (right to buy) | 10250 | $0.00 | 61,185.0000 | 44,628,788 | 14.35% | 0.02% |
| Dec. 5, 2025 | Fitzpatrick Jennifer | Chief Legal Officer | S | Common Stock | 10250 | $40.52 | 0.0000 | 44,628,788 | 100.00% | 0.02% |
| Nov. 24, 2025 | Thompson Peter A. | Director | S | Common Stock | 94583 | $44.54 | 3,610,376.0000 | 44,628,788 | 2.55% | 0.21% |
| Nov. 26, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 1600 | $44.49 | 3,596,886.0000 | 44,628,788 | 0.04% | 0.00% |
| Nov. 25, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 11890 | $44.60 | 3,598,486.0000 | 44,628,788 | 0.33% | 0.03% |
| Nov. 24, 2025 | ORBIMED ADVISORS LLC | Director | S | Common Stock | 94583 | $44.54 | 3,610,376.0000 | 44,628,788 | 2.55% | 0.21% |
| Nov. 26, 2025 | Thompson Peter A. | Director | S | Common Stock | 1600 | $44.49 | 3,596,886.0000 | 44,628,788 | 0.04% | 0.00% |
| Nov. 25, 2025 | Thompson Peter A. | Director | S | Common Stock | 11890 | $44.60 | 3,598,486.0000 | 44,628,788 | 0.33% | 0.03% |
| Nov. 20, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 96 | $40.50 | 6,898,833.0000 | 44,628,788 | 0.00% | 0.00% |
| Nov. 20, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 947 | $39.89 | 167,246.0000 | 44,628,788 | 0.56% | 0.00% |
| Nov. 20, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 1235 | $39.89 | 661,019.0000 | 44,628,788 | 0.19% | 0.00% |
| Nov. 20, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 801 | $39.89 | 2,205,034.0000 | 44,628,788 | 0.04% | 0.00% |
| Nov. 21, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 7609 | $39.50 | 159,033.0000 | 44,628,788 | 4.57% | 0.02% |
| Nov. 21, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 6440 | $39.50 | 2,198,082.0000 | 44,628,788 | 0.29% | 0.01% |
| Nov. 21, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 9924 | $39.50 | 650,307.0000 | 44,628,788 | 1.50% | 0.02% |
| Nov. 21, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 1210 | $39.50 | 6,897,623.0000 | 44,628,788 | 0.02% | 0.00% |
| Nov. 20, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 604 | $40.50 | 166,642.0000 | 44,628,788 | 0.36% | 0.00% |
| Nov. 20, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 512 | $40.50 | 2,204,522.0000 | 44,628,788 | 0.02% | 0.00% |
| Nov. 20, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 150 | $39.89 | 6,898,929.0000 | 44,628,788 | 0.00% | 0.00% |
| Nov. 20, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 788 | $40.50 | 660,231.0000 | 44,628,788 | 0.12% | 0.00% |
| Nov. 19, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 9 | $40.61 | 168,193.0000 | 44,628,788 | 0.01% | 0.00% |
| Nov. 19, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 8 | $40.61 | 2,205,835.0000 | 44,628,788 | 0.00% | 0.00% |
| Nov. 19, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 12 | $40.61 | 662,254.0000 | 44,628,788 | 0.00% | 0.00% |
| Nov. 19, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 2 | $40.61 | 6,899,079.0000 | 44,628,788 | 0.00% | 0.00% |
| Nov. 19, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 14325 | $40.01 | 168,202.0000 | 44,628,788 | 7.85% | 0.03% |
| Nov. 19, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 12126 | $40.01 | 2,205,843.0000 | 44,628,788 | 0.55% | 0.03% |
| Nov. 19, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 18684 | $40.01 | 662,266.0000 | 44,628,788 | 2.74% | 0.04% |
| Nov. 19, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 2276 | $40.01 | 6,899,081.0000 | 44,628,788 | 0.03% | 0.01% |
| Nov. 18, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 2092 | $39.57 | 182,527.0000 | 44,628,788 | 1.13% | 0.00% |
| Nov. 18, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 1770 | $39.57 | 2,217,969.0000 | 44,628,788 | 0.08% | 0.00% |
| Nov. 18, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 2728 | $39.57 | 680,950.0000 | 44,628,788 | 0.40% | 0.01% |
| Nov. 18, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 332 | $39.57 | 6,901,357.0000 | 44,628,788 | 0.00% | 0.00% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 331 | $42.10 | 184,619.0000 | 44,628,788 | 0.18% | 0.00% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 280 | $42.10 | 2,219,739.0000 | 44,628,788 | 0.01% | 0.00% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 433 | $42.10 | 683,678.0000 | 44,628,788 | 0.06% | 0.00% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 53 | $42.10 | 6,901,689.0000 | 44,628,788 | 0.00% | 0.00% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 10707 | $41.05 | 184,950.0000 | 44,628,788 | 5.47% | 0.02% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 9063 | $41.05 | 2,220,019.0000 | 44,628,788 | 0.41% | 0.02% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 13964 | $41.05 | 684,111.0000 | 44,628,788 | 2.00% | 0.03% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 1701 | $41.05 | 6,901,742.0000 | 44,628,788 | 0.02% | 0.00% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 13734 | $40.20 | 195,657.0000 | 44,628,788 | 6.56% | 0.03% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 11626 | $40.20 | 2,229,082.0000 | 44,628,788 | 0.52% | 0.03% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 17913 | $40.20 | 698,075.0000 | 44,628,788 | 2.50% | 0.04% |
| Nov. 17, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 2182 | $40.20 | 6,903,443.0000 | 44,628,788 | 0.03% | 0.00% |
| Oct. 28, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 3624 | $39.58 | 6,905,625.0000 | 0 | 0.05% | 0.00% |
| Oct. 24, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 107941 | $39.50 | 219,867.0000 | 0 | 32.93% | 0.00% |
| Oct. 24, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 66672 | $39.50 | 2,257,826.0000 | 0 | 2.87% | 0.00% |
| Oct. 24, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 122271 | $39.50 | 747,380.0000 | 0 | 14.06% | 0.00% |
| Oct. 24, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 14116 | $39.50 | 6,909,249.0000 | 0 | 0.20% | 0.00% |
| Oct. 28, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 10476 | $39.58 | 209,391.0000 | 0 | 4.76% | 0.00% |
| Oct. 28, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 17118 | $39.58 | 2,240,708.0000 | 0 | 0.76% | 0.00% |
| Oct. 28, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | S | Common Stock | 31392 | $39.58 | 715,988.0000 | 0 | 4.20% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 22895 | $6.11 | 570,238.0000 | 0 | 4.18% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 30049 | $35.63 | 547,343.0000 | 0 | 5.20% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 30049 | $6.11 | 577,392.0000 | 0 | 5.49% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 13324 | $6.11 | 560,667.0000 | 0 | 2.43% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 13324 | $34.44 | 547,343.0000 | 0 | 2.38% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 33532 | $0.00 | 53,142.0000 | 0 | 38.69% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 22895 | $0.00 | 86,674.0000 | 0 | 20.90% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 30049 | $0.00 | 109,569.0000 | 0 | 21.52% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 13324 | $0.00 | 139,618.0000 | 0 | 8.71% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 33532 | $37.31 | 547,343.0000 | 0 | 5.77% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 33532 | $6.11 | 580,875.0000 | 0 | 6.13% | 0.00% |
| Oct. 21, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 22895 | $36.60 | 547,343.0000 | 0 | 4.01% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 4688 | $32.69 | 3,006,332.0000 | 0 | 0.16% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 17 | $36.42 | 2,995,602.0000 | 0 | 0.00% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 83 | $36.42 | 2,995,602.0000 | 0 | 0.00% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 5316 | $35.69 | 2,995,619.0000 | 0 | 0.18% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 25327 | $35.69 | 2,995,685.0000 | 0 | 0.84% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 1210 | $34.91 | 3,000,935.0000 | 0 | 0.04% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 5763 | $34.91 | 3,021,012.0000 | 0 | 0.19% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 4187 | $33.87 | 3,002,145.0000 | 0 | 0.14% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 19948 | $33.87 | 3,026,775.0000 | 0 | 0.65% | 0.00% |
| Oct. 21, 2025 | Booth Bruce | Not found | S | Common Stock | 22339 | $32.69 | 3,046,723.0000 | 0 | 0.73% | 0.00% |
| Oct. 16, 2025 | Booth Bruce | Not found | S | Common Stock | 15384 | $32.84 | 3,107,501.0000 | 0 | 0.49% | 0.00% |
| Oct. 16, 2025 | Booth Bruce | Not found | S | Common Stock | 8596 | $30.15 | 3,312,574.0000 | 0 | 0.26% | 0.00% |
| Oct. 20, 2025 | Booth Bruce | Not found | S | Common Stock | 5412 | $32.33 | 3,084,480.0000 | 0 | 0.18% | 0.00% |
| Oct. 20, 2025 | Booth Bruce | Not found | S | Common Stock | 25788 | $32.33 | 3,084,480.0000 | 0 | 0.83% | 0.00% |
| Oct. 20, 2025 | Booth Bruce | Not found | S | Common Stock | 4300 | $31.79 | 3,089,892.0000 | 0 | 0.14% | 0.00% |
| Oct. 20, 2025 | Booth Bruce | Not found | S | Common Stock | 20485 | $31.79 | 3,110,268.0000 | 0 | 0.65% | 0.00% |
| Oct. 17, 2025 | Booth Bruce | Not found | S | Common Stock | 52 | $33.47 | 3,094,192.0000 | 0 | 0.00% | 0.00% |
| Oct. 17, 2025 | Booth Bruce | Not found | S | Common Stock | 248 | $33.47 | 3,130,753.0000 | 0 | 0.01% | 0.00% |
| Oct. 17, 2025 | Booth Bruce | Not found | S | Common Stock | 4503 | $32.71 | 3,094,244.0000 | 0 | 0.15% | 0.00% |
| Oct. 17, 2025 | Booth Bruce | Not found | S | Common Stock | 21451 | $32.71 | 3,131,001.0000 | 0 | 0.68% | 0.00% |
| Oct. 17, 2025 | Booth Bruce | Not found | S | Common Stock | 6049 | $32.10 | 3,098,747.0000 | 0 | 0.19% | 0.00% |
| Oct. 17, 2025 | Booth Bruce | Not found | S | Common Stock | 28821 | $32.10 | 3,152,452.0000 | 0 | 0.91% | 0.00% |
| Oct. 16, 2025 | Booth Bruce | Not found | S | Common Stock | 2705 | $33.38 | 3,104,796.0000 | 0 | 0.09% | 0.00% |
| Oct. 16, 2025 | Booth Bruce | Not found | S | Common Stock | 73296 | $32.84 | 3,194,161.0000 | 0 | 2.24% | 0.00% |
| Oct. 16, 2025 | Booth Bruce | Not found | S | Common Stock | 12888 | $33.38 | 3,181,273.0000 | 0 | 0.40% | 0.00% |
| Oct. 16, 2025 | Booth Bruce | Not found | S | Common Stock | 9470 | $31.69 | 3,122,885.0000 | 0 | 0.30% | 0.00% |
| Oct. 16, 2025 | Booth Bruce | Not found | S | Common Stock | 45117 | $31.69 | 3,267,457.0000 | 0 | 1.36% | 0.00% |
| Oct. 16, 2025 | Booth Bruce | Not found | S | Common Stock | 1804 | $30.15 | 3,132,355.0000 | 0 | 0.06% | 0.00% |
| Oct. 16, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 10225 | $0.00 | 153,142.0000 | 0 | 6.26% | 0.00% |
| Oct. 15, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 14775 | $6.11 | 562,118.0000 | 0 | 2.70% | 0.00% |
| Oct. 15, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 14775 | $31.11 | 547,343.0000 | 0 | 2.63% | 0.00% |
| Oct. 16, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 10225 | $6.11 | 557,568.0000 | 0 | 1.87% | 0.00% |
| Oct. 16, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 10225 | $31.46 | 547,343.0000 | 0 | 1.83% | 0.00% |
| Oct. 16, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 200 | $6.11 | 547,543.0000 | 0 | 0.04% | 0.00% |
| Oct. 16, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 200 | $34.00 | 547,343.0000 | 0 | 0.04% | 0.00% |
| Oct. 15, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 14775 | $0.00 | 163,367.0000 | 0 | 8.29% | 0.00% |
| Oct. 16, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 200 | $0.00 | 152,942.0000 | 0 | 0.13% | 0.00% |
| Oct. 14, 2025 | Booth Bruce | Not found | S | Common Stock | 105 | $29.95 | 3,390,947.0000 | 0 | 0.00% | 0.00% |
| Oct. 14, 2025 | Booth Bruce | Not found | S | Common Stock | 501 | $29.95 | 3,466,607.0000 | 0 | 0.01% | 0.00% |
| Oct. 13, 2025 | Booth Bruce | Not found | S | Common Stock | 857 | $31.03 | 3,391,052.0000 | 0 | 0.03% | 0.00% |
| Oct. 13, 2025 | Booth Bruce | Not found | S | Common Stock | 4082 | $31.03 | 3,467,108.0000 | 0 | 0.12% | 0.00% |
| Oct. 13, 2025 | Booth Bruce | Not found | S | Common Stock | 9245 | $30.32 | 3,391,909.0000 | 0 | 0.27% | 0.00% |
| Oct. 13, 2025 | Booth Bruce | Not found | S | Common Stock | 44048 | $30.32 | 3,471,190.0000 | 0 | 1.25% | 0.00% |
| Oct. 10, 2025 | Booth Bruce | Not found | S | Common Stock | 3511 | $29.98 | 3,401,154.0000 | 0 | 0.10% | 0.00% |
| Oct. 10, 2025 | Booth Bruce | Not found | S | Common Stock | 16727 | $29.98 | 3,515,238.0000 | 0 | 0.47% | 0.00% |
| Oct. 15, 2025 | Booth Bruce | Not found | S | Common Stock | 6303 | $31.12 | 3,370,849.0000 | 0 | 0.19% | 0.00% |
| Oct. 15, 2025 | Booth Bruce | Not found | S | Common Stock | 30032 | $31.12 | 3,370,849.0000 | 0 | 0.88% | 0.00% |
| Oct. 15, 2025 | Booth Bruce | Not found | S | Common Stock | 13795 | $30.37 | 3,377,152.0000 | 0 | 0.41% | 0.00% |
| Oct. 15, 2025 | Booth Bruce | Not found | S | Common Stock | 65726 | $30.37 | 3,400,881.0000 | 0 | 1.90% | 0.00% |
| Oct. 6, 2025 | Booth Bruce | Not found | S | Common Stock | 2047 | $29.95 | 3,565,781.0000 | 0 | 0.06% | 0.00% |
| Oct. 6, 2025 | Booth Bruce | Not found | S | Common Stock | 9753 | $29.95 | 3,565,781.0000 | 0 | 0.27% | 0.00% |
| Oct. 3, 2025 | Booth Bruce | Not found | S | Common Stock | 6548 | $30.00 | 3,567,828.0000 | 0 | 0.18% | 0.00% |
| Oct. 3, 2025 | Booth Bruce | Not found | S | Common Stock | 31198 | $30.00 | 3,575,534.0000 | 0 | 0.86% | 0.00% |
| Oct. 1, 2025 | Beer Caroline Stark | Chief Business Officer | A | Non-Qualified Stock Option (right to buy) | 255000 | $0.00 | 255,000.0000 | 0 | 9999.99% | 0.00% |
| Oct. 1, 2025 | Booth Bruce | Not found | S | Common Stock | 165 | $29.95 | 3,615,327.0000 | 0 | 0.00% | 0.00% |
| Oct. 1, 2025 | Booth Bruce | Not found | S | Common Stock | 35 | $29.95 | 3,615,327.0000 | 0 | 0.00% | 0.00% |
| Sept. 30, 2025 | Booth Bruce | Not found | S | Common Stock | 2149 | $30.06 | 3,615,362.0000 | 0 | 0.06% | 0.00% |
| Sept. 30, 2025 | Booth Bruce | Not found | S | Common Stock | 10239 | $30.06 | 3,615,492.0000 | 0 | 0.28% | 0.00% |
| Sept. 29, 2025 | Booth Bruce | Not found | S | Common Stock | 11468 | $30.09 | 3,617,511.0000 | 0 | 0.32% | 0.00% |
| Sept. 29, 2025 | Booth Bruce | Not found | S | Common Stock | 54637 | $30.09 | 3,625,731.0000 | 0 | 1.48% | 0.00% |
| Sept. 26, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 17207 | $0.00 | 185,935.0000 | 0 | 8.47% | 0.00% |
| Sept. 29, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 7793 | $0.00 | 178,142.0000 | 0 | 4.19% | 0.00% |
| Sept. 29, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 7793 | $29.70 | 547,343.0000 | 0 | 1.40% | 0.00% |
| Sept. 29, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 7793 | $6.11 | 555,136.0000 | 0 | 1.42% | 0.00% |
| Sept. 26, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 17207 | $28.85 | 547,343.0000 | 0 | 3.05% | 0.00% |
| Sept. 26, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 17207 | $6.11 | 564,550.0000 | 0 | 3.14% | 0.00% |
| Sept. 4, 2025 | Fitzpatrick Jennifer | Chief Legal Officer | M | Common Stock | 10250 | $6.11 | 10,250.0000 | 0 | 9999.99% | 0.00% |
| Sept. 4, 2025 | Fitzpatrick Jennifer | Chief Legal Officer | M | Non-Qualified Stock Option (right to buy) | 10250 | $0.00 | 71,435.0000 | 0 | 12.55% | 0.00% |
| Sept. 4, 2025 | Fitzpatrick Jennifer | Chief Legal Officer | S | Common Stock | 10250 | $23.12 | 0.0000 | 0 | 100.00% | 0.00% |
| Sept. 2, 2025 | Ridloff Elena | CFO & Head of Corp. Dev. | S | Common Stock | 8836 | $25.08 | 38,532.0000 | 0 | 18.65% | 0.00% |
| Aug. 29, 2025 | Ridloff Elena | CFO & Head of Corp. Dev. | S | Common Stock | 748 | $25.18 | 47,368.0000 | 0 | 1.55% | 0.00% |
| Aug. 26, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 17574 | $0.00 | 210,568.0000 | 0 | 7.70% | 0.00% |
| Aug. 27, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 7426 | $25.01 | 547,343.0000 | 0 | 1.34% | 0.00% |
| Aug. 27, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 7426 | $6.11 | 554,769.0000 | 0 | 1.36% | 0.00% |
| Aug. 26, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 17574 | $24.96 | 547,343.0000 | 0 | 3.11% | 0.00% |
| Aug. 26, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 17574 | $6.11 | 564,917.0000 | 0 | 3.21% | 0.00% |
| Aug. 28, 2025 | Ridloff Elena | CFO & Head of Corp. Dev. | S | Common Stock | 16098 | $25.97 | 48,116.0000 | 0 | 25.07% | 0.00% |
| Aug. 26, 2025 | Ridloff Elena | CFO & Head of Corp. Dev. | S | Common Stock | 3700 | $25.13 | 67,832.0000 | 0 | 5.17% | 0.00% |
| Aug. 27, 2025 | Ridloff Elena | CFO & Head of Corp. Dev. | S | Common Stock | 3618 | $25.10 | 64,214.0000 | 0 | 5.33% | 0.00% |
| Aug. 27, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 7426 | $0.00 | 203,142.0000 | 0 | 3.53% | 0.00% |
| Aug. 20, 2025 | Cloonan Michael | President & CEO | M | Common Stock | 25000 | $6.11 | 572,343.0000 | 0 | 4.57% | 0.00% |
| Aug. 20, 2025 | Cloonan Michael | President & CEO | S | Common Stock | 25000 | $22.75 | 547,343.0000 | 0 | 4.37% | 0.00% |
| Aug. 20, 2025 | Cloonan Michael | President & CEO | M | Non-Qualified Stock Option (right to buy) | 25000 | $0.00 | 228,142.0000 | 0 | 9.88% | 0.00% |
| Aug. 19, 2025 | Ridloff Elena | CFO & Head of Corp. Dev. | S | Common Stock | 34500 | $21.08 | 89,032.0000 | 0 | 27.93% | 0.00% |
| Aug. 20, 2025 | Ridloff Elena | CFO & Head of Corp. Dev. | S | Common Stock | 17500 | $22.69 | 71,532.0000 | 0 | 19.66% | 0.00% |
| June 27, 2025 | TPG GP A, LLC | TenPercentOwner | P | Common Stock | 60000 | $15.84 | 6,744,962.0000 | 0 | 0.90% | 0.00% |
| June 12, 2025 | Booth Bruce | Director | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2025 | Clancy Paul J | Director | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2025 | Fleming Harold Edward | Director | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2025 | Resnick Joshua | Director | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2025 | Ruddy Marcella K. | Director | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2025 | Stelzer Laurie | Director | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2025 | Thompson Peter A. | Director | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2025 | Viney Joanne L. | Director | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| June 12, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | A | Non-Qualified Stock Option (right to buy) | 19959 | $0.00 | 19,959.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | TPG GP A, LLC | TenPercentOwner | C | Series A Preferred Stock | 1806318 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | TPG GP A, LLC | TenPercentOwner | C | Series Seed Preferred Stock | 1276276 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | TPG GP A, LLC | TenPercentOwner | P | Common Stock | 1125000 | $18.00 | 6,684,962.0000 | 0 | 20.23% | 0.00% |
| Feb. 10, 2025 | TPG GP A, LLC | TenPercentOwner | C | Common Stock | 4875547 | $0.00 | 5,559,962.0000 | 0 | 712.37% | 0.00% |
| Feb. 10, 2025 | TPG GP A, LLC | TenPercentOwner | C | Series C Preferred Stock | 1765541 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | TPG GP A, LLC | TenPercentOwner | C | Series B Preferred Stock | 2275528 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Thompson Peter A. | Not found | C | Common Stock | 3154959 | $0.00 | 3,154,959.0000 | 0 | 9999.99% | 0.00% |
| Feb. 6, 2025 | Ridloff Elena | CFO & Head of Corp. Dev. | A | Stock Option (Right to Buy) | 157820 | $0.00 | 157,820.0000 | 0 | 9999.99% | 0.00% |
| Feb. 6, 2025 | Cloonan Michael | President & CEO | A | Stock Option (Right to Buy) | 450252 | $0.00 | 450,252.0000 | 0 | 9999.99% | 0.00% |
| Feb. 6, 2025 | Viney Joanne L. | Not found | A | Stock Option (Right to Buy) | 39919 | $0.00 | 39,919.0000 | 0 | 9999.99% | 0.00% |
| Feb. 6, 2025 | Ruddy Marcella K. | Not found | A | Stock Option (Right to Buy) | 39919 | $0.00 | 39,919.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | ORBIMED ADVISORS LLC | Director | C | Series C convertible preferred stock | 2048760 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | ORBIMED ADVISORS LLC | Director | C | Series B convertible preferred stock | 2560951 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | ORBIMED ADVISORS LLC | Director | P | Common Stock | 550000 | $18.00 | 3,704,959.0000 | 0 | 17.43% | 0.00% |
| Feb. 10, 2025 | ORBIMED ADVISORS LLC | Director | C | Common Stock | 3154959 | $0.00 | 3,154,959.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series C Preferred Stock | 1091219 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series C Preferred Stock | 4364874 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series B Preferred Stock | 2155469 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series B Preferred Stock | 923773 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series A Preferred Stock | 124908 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series A Preferred Stock | 451580 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series A Preferred Stock | 1229830 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series Seed Preferred Stock | 138054 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series Seed Preferred Stock | 319069 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Series Seed Preferred Stock | 819153 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | P | Common Stock | 102414 | $18.00 | 2,324,498.0000 | 0 | 4.61% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | P | Common Stock | 1022586 | $18.00 | 6,923,365.0000 | 0 | 17.33% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Common Stock | 179975 | $0.00 | 327,808.0000 | 0 | 121.74% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Common Stock | 2222084 | $0.00 | 2,222,084.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Common Stock | 527444 | $0.00 | 869,651.0000 | 0 | 154.13% | 0.00% |
| Feb. 10, 2025 | RA CAPITAL MANAGEMENT, L.P. | Not found | C | Common Stock | 5021990 | $0.00 | 5,900,779.0000 | 0 | 571.47% | 0.00% |
| Feb. 10, 2025 | Atlas Venture Fund XI, L.P. | Not found | C | Series Seed convertible preferred stock | 1051051 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Atlas Venture Fund XI, L.P. | Not found | C | Series C convertible preferred stock | 61463 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Atlas Venture Fund XI, L.P. | Not found | C | Series C convertible preferred stock | 1092504 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 6, 2025 | McKee Charlotte | Chief Medical Officer | A | Stock Option (Right to Buy) | 148536 | $0.00 | 148,536.0000 | 0 | 9999.99% | 0.00% |
| Feb. 10, 2025 | Atlas Venture Fund XI, L.P. | Not found | C | Series A convertible preferred stock | 1806317 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Atlas Venture Fund XI, L.P. | Not found | C | Series B convertible preferred stock | 1298332 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Atlas Venture Fund XI, L.P. | Not found | P | Common Stock | 60000 | $18.00 | 3,694,020.0000 | 0 | 1.65% | 0.00% |
| Feb. 10, 2025 | Atlas Venture Fund XI, L.P. | Not found | C | Common Stock | 747727 | $0.00 | 3,634,020.0000 | 0 | 25.91% | 0.00% |
| Feb. 10, 2025 | Atlas Venture Fund XI, L.P. | Not found | C | Common Stock | 2886293 | $0.00 | 3,694,020.0000 | 0 | 357.34% | 0.00% |
| Feb. 10, 2025 | Booth Bruce | Not found | C | Series C convertible preferred stock | 1092504 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Booth Bruce | Not found | C | Series C convertible preferred stock | 61463 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Booth Bruce | Not found | C | Series B convertible preferred stock | 1298332 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Booth Bruce | Not found | C | Series A convertible preferred stock | 1806317 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Booth Bruce | Not found | P | Common Stock | 60000 | $18.00 | 3,694,020.0000 | 0 | 1.65% | 0.00% |
| Feb. 10, 2025 | Booth Bruce | Not found | C | Series Seed convertible preferred stock | 1051051 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Booth Bruce | Not found | C | Common Stock | 747727 | $0.00 | 3,634,020.0000 | 0 | 25.91% | 0.00% |
| Feb. 10, 2025 | Booth Bruce | Not found | C | Common Stock | 2886293 | $0.00 | 3,694,020.0000 | 0 | 357.34% | 0.00% |
| Feb. 10, 2025 | Thompson Peter A. | Not found | C | Series C convertible preferred stock | 2048760 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Thompson Peter A. | Not found | C | Series B convertible preferred stock | 2560951 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 10, 2025 | Thompson Peter A. | Not found | P | Common Stock | 550000 | $18.00 | 3,704,959.0000 | 0 | 17.43% | 0.00% |