SEC Insider Transactions from PYOTT DAVID E I.

Last updated: 2026-03-14 11:51 UTC | Total transactions: 21

David E. I. Pyott, a director at Alnylam Pharmaceuticals ($ALNY), sold shares once on the open market in the last year, totaling $2.2 million. His most recent sale occurred on March 24, 2025. These sales rank 3,290th among nearly 12,000 individual insiders, where the average is about $8.6 million across roughly six transactions. Pyott made no open market purchases during this period.

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Transaction Date Company Ticker Insider Name Title Transaction Type Security Shares Price Shares Owned Following Total Shares Outstanding % of Owned % of Outstanding
Feb. 18, 2026 Tarsus Pharmaceuticals, Inc. $TARS PYOTT DAVID E I Director A Stock Option (right to buy) 5893 $0.00 5,893.0000 42,607,717 9999.99% 0.01%
Feb. 18, 2026 Tarsus Pharmaceuticals, Inc. $TARS PYOTT DAVID E I Director A Restricted Stock Units 3729 $0.00 3,729.0000 42,607,717 9999.99% 0.01%
June 5, 2025 PLIANT THERAPEUTICS, INC. $PLRX PYOTT DAVID E I Director A Common Stock (Right to Buy) 30000 $0.00 30,000.0000 61,236,291 9999.99% 0.05%
May 8, 2025 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director A Common Stock 775 $0.00 28,811.0000 127,651,000 2.76% 0.00%
May 8, 2025 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director A Stock Option (right to buy) 1558 $0.00 1,558.0000 127,651,000 9999.99% 0.00%
March 24, 2025 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director M Common Stock 7440 $88.95 35,476.0000 127,651,000 26.54% 0.01%
March 24, 2025 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director M Stock Option (right to buy) 7440 $0.00 0.0000 127,651,000 100.00% 0.01%
March 24, 2025 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director S Common Stock 7440 $299.00 28,036.0000 127,651,000 20.97% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director S Common Stock 17560 $220.00 42,926.0000 124,906,000 29.03% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director S Common Stock 7420 $221.00 35,506.0000 124,906,000 17.29% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director S Common Stock 7470 $222.00 28,036.0000 124,906,000 21.04% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director M Stock Option (right to buy) 7420 $0.00 3,830.0000 124,906,000 65.96% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director M Stock Option (right to buy) 7470 $0.00 3,780.0000 124,906,000 66.40% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director M Common Stock 17560 $88.95 45,596.0000 124,906,000 62.63% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director M Stock Option (right to buy) 17560 $0.00 7,440.0000 124,906,000 70.24% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director M Common Stock 7420 $70.20 53,016.0000 124,906,000 16.27% 0.01%
June 24, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director M Common Stock 7470 $71.99 60,486.0000 124,906,000 14.09% 0.01%
June 13, 2024 PLIANT THERAPEUTICS, INC. $PLRX PYOTT DAVID E I Director A Common Stock (Right to Buy) 26764 $0.00 26,764.0000 0 9999.99% 0.00%
May 21, 2024 BIOMARIN PHARMACEUTICAL INC $BMRN PYOTT DAVID E I Director A Common Stock 4720 $0.00 49,750.0000 191,595,000 10.48% 0.00%
May 16, 2024 ALNYLAM PHARMACEUTICALS, INC. $ALNY PYOTT DAVID E I Director A Stock Option (right to buy) 5228 $0.00 5,228.0000 124,906,000 9999.99% 0.00%
May 23, 2023 BIOMARIN PHARMACEUTICAL INC $BMRN PYOTT DAVID E I Director A Common Stock 4190 $0.00 45,030.0000 188,963,000 10.26% 0.00%