Mathers Edward T made notable open market buys of SpyGlass Pharma ($SGP) shares worth 15 million dollars on February 9, 2026, ranking 81st among 4,983 insiders with an average purchase of 1.5 million dollars. He also bought Korro Bio ($KRRO) shares for 2.3 million dollars on March 10, 2026, ranking 280th. In contrast, he sold NeueHealth ($NEUE) shares three times for about 24,500 dollars, with the latest on October 2, 2025, ranking 10,934th among 11,678 insiders averaging 8.6 million dollars per seller.
| Transaction Date | Company | Ticker | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| March 12, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | J | Common Stock | 4199 | $0.00 | 21,168.0000 | 64,984,361 | 24.75% | 0.01% |
| March 10, 2026 | Korro Bio, Inc. | $KRRO | Mathers Edward T | Not found | P | Pre-Funded Warrants | 242945 | $11.11 | 242,945.0000 | 9,417,295 | 9999.99% | 2.58% |
| March 10, 2026 | Korro Bio, Inc. | $KRRO | Mathers Edward T | Not found | P | Common Stock | 207100 | $11.11 | 1,297,893.0000 | 9,417,295 | 18.99% | 2.20% |
| March 2, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | J | Common Stock | 4198 | $0.00 | 16,969.0000 | 64,984,361 | 32.87% | 0.01% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | C | Series D Preferred Stock | 737962 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | C | Series C-2 Preferred Stock | 1370168 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | C | Series C-1 Preferred Stock | 1370168 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | C | Series B Preferred Stock | 1619240 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | P | Common Stock | 937500 | $16.00 | 6,035,038.0000 | 0 | 18.39% | 0.00% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | C | Common Stock | 737962 | $0.00 | 5,097,538.0000 | 0 | 16.93% | 0.00% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | C | Common Stock | 1370168 | $0.00 | 4,359,576.0000 | 0 | 45.83% | 0.00% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | C | Common Stock | 1370168 | $0.00 | 2,989,408.0000 | 0 | 84.62% | 0.00% |
| Feb. 9, 2026 | SpyGlass Pharma, Inc. | $SGP | Mathers Edward T | Not found | C | Common Stock | 1619240 | $0.00 | 1,619,240.0000 | 0 | 9999.99% | 0.00% |
| Dec. 31, 2025 | OnKure Therapeutics, Inc. | $OKUR | Mathers Edward T | Not found | A | Class A Common Stock | 3911 | $0.00 | 15,310.0000 | 13,530,892 | 34.31% | 0.03% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | X | Warrant (Right to Buy) | 1656789 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 18.36% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | X | Common Stock | 189195 | $0.01 | 488,982.0000 | 9,024,240 | 63.11% | 2.10% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | S | Common Stock | 280 | $6.75 | 488,702.0000 | 9,024,240 | 0.06% | 0.00% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | M | Common Stock | 186128 | $0.01 | 674,830.0000 | 9,024,240 | 38.09% | 2.06% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | F | Common Stock | 276 | $6.75 | 674,554.0000 | 9,024,240 | 0.04% | 0.00% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | D | Common Stock | 674554 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 7.47% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | X | Common Stock | 1656789 | $0.01 | 1,656,789.0000 | 9,024,240 | 9999.99% | 18.36% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | S | Common Stock | 2455 | $6.75 | 1,654,334.0000 | 9,024,240 | 0.15% | 0.03% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | X | Common Stock | 607536 | $0.01 | 2,261,870.0000 | 9,024,240 | 36.72% | 6.73% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | S | Common Stock | 900 | $6.75 | 2,260,970.0000 | 9,024,240 | 0.04% | 0.01% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | M | Common Stock | 124085 | $0.01 | 2,385,055.0000 | 9,024,240 | 5.49% | 1.38% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | F | Common Stock | 182 | $6.75 | 2,384,873.0000 | 9,024,240 | 0.01% | 0.00% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | D | Common Stock | 2384873 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 26.43% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | X | Warrant (Right to Buy) | 189195 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 2.10% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | A | Warrant (Right to Buy) | 186128 | $0.00 | 186,128.0000 | 9,024,240 | 9999.99% | 2.06% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | M | Warrant (Right to Buy) | 186128 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 2.06% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | D | Series A Convertible Perpetual Preferred Stock | 75000 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 0.83% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | D | Series B Convertible Perpetual Preferred Stock | 37700 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 0.42% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | X | Warrant (Right to Buy) | 607536 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 6.73% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | A | Warrant (Right to Buy) | 124085 | $0.00 | 124,085.0000 | 9,024,240 | 9999.99% | 1.38% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | M | Warrant (Right to Buy) | 124085 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 1.38% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | D | Series A Convertible Perpetual Preferred Stock | 125000 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 1.39% |
| Oct. 2, 2025 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | D | Series B Convertible Perpetual Preferred Stock | 100000 | $0.00 | 0.0000 | 9,024,240 | 100.00% | 1.11% |
| Sept. 30, 2025 | OnKure Therapeutics, Inc. | $OKUR | Mathers Edward T | Not found | A | Class A Common Stock | 4125 | $0.00 | 11,399.0000 | 3,447,071 | 56.71% | 0.12% |
| June 30, 2025 | OnKure Therapeutics, Inc. | $OKUR | Mathers Edward T | Not found | A | Class A Common Stock | 4694 | $0.00 | 7,274.0000 | 3,447,071 | 181.94% | 0.14% |
| June 25, 2025 | Senti Biosciences, Inc. | $SNTI | Mathers Edward T | Not found | A | Stock Option (Right to Buy) | 21950 | $0.00 | 21,950.0000 | 26,004,366 | 9999.99% | 0.08% |
| June 24, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | A | Restricted Stock Units | 4712 | $0.00 | 4,712.0000 | 63,059,165 | 9999.99% | 0.01% |
| June 24, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | A | Stock Option (right to buy) | 7037 | $0.00 | 7,037.0000 | 63,059,165 | 9999.99% | 0.01% |
| June 18, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | M | Common Stock | 4000 | $0.00 | 12,771.0000 | 63,059,165 | 45.60% | 0.01% |
| June 18, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | M | Restricted Stock Units | 4000 | $0.00 | 0.0000 | 63,059,165 | 100.00% | 0.01% |
| June 11, 2025 | Trevi Therapeutics, Inc. | $TRVI | Mathers Edward T | Not found | A | Nonstatutory Stock Option (right to buy) | 45000 | $0.00 | 45,000.0000 | 101,971,873 | 9999.99% | 0.04% |
| June 5, 2025 | MBX Biosciences, Inc. | $MBX | Mathers Edward T | Not found | A | Stock option (right to buy) | 16000 | $0.00 | 16,000.0000 | 33,424,371 | 9999.99% | 0.05% |
| May 28, 2025 | OnKure Therapeutics, Inc. | $OKUR | Mathers Edward T | Not found | A | Stock Option (right to buy) | 7650 | $0.00 | 7,650.0000 | 3,447,071 | 9999.99% | 0.22% |
| March 31, 2025 | OnKure Therapeutics, Inc. | $OKUR | Mathers Edward T | Not found | A | Class A Common Stock | 2580 | $0.00 | 2,580.0000 | 3,447,071 | 9999.99% | 0.07% |
| March 7, 2025 | Senti Biosciences, Inc. | $SNTI | Mathers Edward T | Not found | A | Stock Option (Right to Buy) | 43900 | $0.00 | 43,900.0000 | 4,829,035 | 9999.99% | 0.91% |
| Oct. 4, 2024 | OnKure Therapeutics, Inc. | $OKUR | Mathers Edward T | Not found | A | Stock Option (right to buy) | 15300 | $0.00 | 15,300.0000 | 316,142 | 9999.99% | 4.84% |
| Oct. 1, 2024 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | P | Warrant (Right to Buy) | 185595 | $0.00 | 742,376.0000 | 0 | 33.33% | 0.00% |
| Oct. 1, 2024 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | P | Warrant (Right to Buy) | 61865 | $0.00 | 742,376.0000 | 0 | 9.09% | 0.00% |
| Sept. 16, 2024 | MBX Biosciences, Inc. | $MBX | Mathers Edward T | Not found | C | Common Stock | 1023103 | $0.00 | 1,023,103.0000 | 0 | 9999.99% | 0.00% |
| Sept. 16, 2024 | MBX Biosciences, Inc. | $MBX | Mathers Edward T | Not found | C | Series A Convertible Preferred Stock | 12299854 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Sept. 16, 2024 | MBX Biosciences, Inc. | $MBX | Mathers Edward T | Not found | C | Series B Convertible Preferred Stock | 25142840 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Sept. 16, 2024 | MBX Biosciences, Inc. | $MBX | Mathers Edward T | Not found | P | Common Stock | 500000 | $16.00 | 3,614,486.0000 | 0 | 16.05% | 0.00% |
| Sept. 16, 2024 | MBX Biosciences, Inc. | $MBX | Mathers Edward T | Not found | C | Common Stock | 2091383 | $0.00 | 3,114,486.0000 | 0 | 204.42% | 0.00% |
| Sept. 12, 2024 | MBX Biosciences, Inc. | $MBX | Mathers Edward T | Not found | A | Stock Option (Right to Buy) | 15963 | $0.00 | 15,963.0000 | 0 | 9999.99% | 0.00% |
| July 10, 2024 | Senti Biosciences, Inc. | $SNTI | Mathers Edward T | Not found | A | Stock Option (Right to Buy) | 62500 | $0.00 | 62,500.0000 | 4,572,432 | 9999.99% | 1.37% |
| June 21, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | M | Common Stock | 3000 | $0.00 | 8,771.0000 | 60,143,558 | 51.98% | 0.00% |
| June 21, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | M | Restricted Stock Units | 3000 | $0.00 | 0.0000 | 60,143,558 | 100.00% | 0.00% |
| June 18, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | A | Stock Option (right to buy) | 14000 | $0.00 | 14,000.0000 | 60,143,558 | 9999.99% | 0.02% |
| June 18, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Not found | A | Restricted Stock Units | 4000 | $0.00 | 4,000.0000 | 60,143,558 | 9999.99% | 0.01% |
| June 13, 2024 | Trevi Therapeutics, Inc. | $TRVI | Mathers Edward T | Not found | A | Nonstatutory Stock Option (right to buy) | 30000 | $0.00 | 30,000.0000 | 99,033,373 | 9999.99% | 0.03% |
| April 22, 2024 | Korro Bio, Inc. | $KRRO | Mathers Edward T | Not found | P | Common Stock | 17857 | $56.00 | 1,090,793.0000 | 0 | 1.66% | 0.00% |
| April 8, 2024 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | P | Warrant (Right to Buy) | 371187 | $0.00 | 494,916.0000 | 0 | 300.00% | 0.00% |
| April 8, 2024 | NeueHealth, Inc. | $NEUE | Mathers Edward T | Not found | P | Warrant (Right to Buy) | 123729 | $0.00 | 494,916.0000 | 0 | 33.33% | 0.00% |
| Dec. 19, 2023 | NeueHealth, Inc. | $NEUE | Mathers Edward T | TenPercentOwner | P | Warrant (Right to Buy) | 175525 | $0.00 | 1,656,789.0000 | 0 | 11.85% | 0.00% |
| Oct. 31, 2023 | NeueHealth, Inc. | $NEUE | Mathers Edward T | TenPercentOwner | P | Warrant (Right to Buy) | 100606 | $0.00 | 1,481,264.0000 | 0 | 7.29% | 0.00% |
| Sept. 15, 2023 | NeueHealth, Inc. | $NEUE | Mathers Edward T | TenPercentOwner | P | Warrant (Right to Buy) | 552263 | $0.00 | 1,380,658.0000 | 0 | 66.67% | 0.00% |
| Aug. 11, 2023 | NeueHealth, Inc. | $NEUE | Mathers Edward T | TenPercentOwner | P | Warrant (Right to Buy) | 828395 | $0.00 | 828,395.0000 | 0 | 9999.99% | 0.00% |
| July 17, 2023 | Savara Inc | $SVRA | Mathers Edward T | TenPercentOwner | P | Common Stock | 333333 | $3.00 | 24,471,264.0000 | 0 | 1.38% | 0.00% |
| June 22, 2023 | SYNLOGIC, INC. | $SYBX | Mathers Edward T | Director | A | Stock Option (right to buy) | 30000 | $0.00 | 30,000.0000 | 0 | 9999.99% | 0.00% |
| June 21, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Director | A | Restricted Stock Units | 3000 | $0.00 | 3,000.0000 | 56,708,975 | 9999.99% | 0.01% |
| June 21, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Director | A | Stock Option (right to buy) | 14000 | $0.00 | 14,000.0000 | 56,708,975 | 9999.99% | 0.02% |
| June 16, 2023 | Senti Biosciences, Inc. | $SNTI | Mathers Edward T | Director | A | Stock Option (Right to Buy) | 62500 | $0.00 | 62,500.0000 | 4,406,137 | 9999.99% | 1.42% |
| June 6, 2023 | OnKure Therapeutics, Inc. | $OKUR | Mathers Edward T | Director | A | Stock Option (right to buy) | 17500 | $0.00 | 17,500.0000 | 0 | 50.00% | 0.00% |
| March 2, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Mathers Edward T | Director | J | Common Stock | 5771 | $0.00 | 5,771.0000 | 52,120,701 | 9999.99% | 0.01% |