OnKure Therapeutics, Inc. ($OKUR) Insider Transactions

Last updated: 2026-04-03 21:06 UTC | Total transactions: 89

In the last 12 months, insiders at OnKure Therapeutics, Inc. ($OKUR) filed 89 transactions with the SEC: 14 open-market purchases totaling $5,315,495 and 16 sales totaling $4,235,524. Net insider sentiment: net buying.

OnKure Therapeutics, Inc. operates in the Pharmaceutical preparations industry (Life sciences sector).

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View all SEC Filings for OnKure Therapeutics, Inc. (OKUR).

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Recent Insider Transactions

Transaction Date Insider Name Title Transaction Type Security Shares Price Shares Owned Following Total Shares Outstanding % of Owned % of Outstanding
April 1, 2026 Saccomano Nicholas A President and CEO A Employee Stock Option (right to buy) 330000 $0.00 330,000.0000 13,530,892 9999.99% 2.44%
April 1, 2026 Leverone Jason A. Chief Financial Officer A Employee Stock Option (right to buy) 110000 $0.00 110,000.0000 13,530,892 9999.99% 0.81%
April 1, 2026 Hartley Dylan Chief Scientific Officer A Employee Stock Option (right to buy) 110000 $0.00 110,000.0000 13,530,892 9999.99% 0.81%
April 1, 2026 Agresta Samuel Chief Medical Officer A Employee Stock Option (right to buy) 110000 $0.00 110,000.0000 13,530,892 9999.99% 0.81%
March 31, 2026 Ratcliffe Liam Not found A Stock Option (right to buy) 15300 $0.00 15,300.0000 13,530,892 9999.99% 0.11%
March 23, 2026 Saccomano Nicholas A President and CEO S Class A Common Stock 86 $4.16 7,333.0000 13,530,892 1.16% 0.00%
March 23, 2026 Leverone Jason A. Chief Financial Officer S Class A Common Stock 301 $4.16 16,000.0000 13,530,892 1.85% 0.00%
Dec. 31, 2025 Mathers Edward T Not found A Class A Common Stock 3911 $0.00 15,310.0000 13,530,892 34.31% 0.03%
Dec. 31, 2025 Manke Isaac Not found A Class A Common Stock 5258 $0.00 20,583.0000 13,530,892 34.31% 0.04%
Dec. 22, 2025 Leverone Jason A. Chief Financial Officer S Class A Common Stock 302 $2.97 16,301.0000 13,530,892 1.82% 0.00%
Dec. 22, 2025 Saccomano Nicholas A President and CEO S Class A Common Stock 87 $2.97 7,419.0000 13,530,892 1.16% 0.00%
Sept. 30, 2025 Manke Isaac Not found A Class A Common Stock 5545 $0.00 15,325.0000 3,447,071 56.70% 0.16%
Sept. 30, 2025 Mathers Edward T Not found A Class A Common Stock 4125 $0.00 11,399.0000 3,447,071 56.71% 0.12%
Sept. 22, 2025 Leverone Jason A. Chief Financial Officer S Class A Common Stock 303 $2.62 12,603.0000 3,447,071 2.35% 0.01%
Sept. 22, 2025 Saccomano Nicholas A President and CEO S Class A Common Stock 88 $2.62 3,506.0000 3,447,071 2.45% 0.00%
June 30, 2025 Manke Isaac Not found A Class A Common Stock 6311 $0.00 9,780.0000 3,447,071 181.93% 0.18%
June 30, 2025 Mathers Edward T Not found A Class A Common Stock 4694 $0.00 7,274.0000 3,447,071 181.94% 0.14%
June 23, 2025 Leverone Jason A. Chief Financial Officer S Class A Common Stock 303 $2.38 12,906.0000 3,447,071 2.29% 0.01%
June 23, 2025 Saccomano Nicholas A President and CEO S Class A Common Stock 88 $2.38 3,594.0000 3,447,071 2.39% 0.00%
May 28, 2025 Phillips Andrew John Not found A Stock Option (right to buy) 7650 $0.00 7,650.0000 3,447,071 9999.99% 0.22%
May 28, 2025 Mathers Edward T Not found A Stock Option (right to buy) 7650 $0.00 7,650.0000 3,447,071 9999.99% 0.22%
May 28, 2025 Manke Isaac Not found A Stock Option (right to buy) 7650 $0.00 7,650.0000 3,447,071 9999.99% 0.22%
May 28, 2025 Jansen Valerie Malyvanh Not found A Stock Option (right to buy) 7650 $0.00 7,650.0000 3,447,071 9999.99% 0.22%
May 28, 2025 GREY MICHAEL G Not found A Stock Option (right to buy) 7650 $0.00 7,650.0000 3,447,071 9999.99% 0.22%
May 28, 2025 Carruthers R Michael Not found A Stock Option (right to buy) 7650 $0.00 7,650.0000 3,447,071 9999.99% 0.22%
May 15, 2025 Cormorant Asset Management, LP Not found S Class A Common Stock 1813439 $1.85 0.0000 3,447,071 100.00% 52.61%
May 15, 2025 ACORN BIOVENTURES, L.P. Not found P Common Stock 1129730 $1.85 2,839,674.0000 3,447,071 66.07% 32.77%
May 15, 2025 ACORN BIOVENTURES, L.P. Not found P Common Stock 270270 $1.85 2,839,674.0000 3,447,071 10.52% 7.84%
May 12, 2025 Cormorant Asset Management, LP Not found S Class A Common Stock 24300 $1.99 1,813,439.0000 3,447,071 1.32% 0.70%
April 7, 2025 Saccomano Nicholas A President and CEO S Class A Common Stock 516 $2.67 3,682.0000 3,447,071 12.29% 0.01%
April 7, 2025 Leverone Jason A. Chief Financial Officer S Class A Common Stock 1844 $2.67 13,209.0000 3,447,071 12.25% 0.05%
April 4, 2025 Saccomano Nicholas A President and CEO S Class A Common Stock 358 $3.33 4,198.0000 3,447,071 7.86% 0.01%
April 4, 2025 Leverone Jason A. Chief Financial Officer S Class A Common Stock 1278 $3.33 15,053.0000 3,447,071 7.83% 0.04%
March 31, 2025 Manke Isaac Not found A Class A Common Stock 3469 $0.00 3,469.0000 3,447,071 9999.99% 0.10%
March 31, 2025 Mathers Edward T Not found A Class A Common Stock 2580 $0.00 2,580.0000 3,447,071 9999.99% 0.07%
Jan. 27, 2025 Saccomano Nicholas A President and CEO A Employee Stock Option (right to buy) 130000 $0.00 130,000.0000 3,447,071 9999.99% 3.77%
Jan. 27, 2025 Hartley Dylan Chief Scientific Officer A Employee Stock Option (right to buy) 45000 $0.00 45,000.0000 3,447,071 9999.99% 1.31%
Jan. 27, 2025 Leverone Jason A. Chief Financial Officer A Employee Stock Option (right to buy) 65000 $0.00 65,000.0000 3,447,071 9999.99% 1.89%
Jan. 27, 2025 Agresta Samuel Chief Medical Officer A Employee Stock Option (right to buy) 45000 $0.00 45,000.0000 3,447,071 9999.99% 1.31%
Oct. 7, 2024 Leonard Braden Michael Not found J Common Stock 345739 $0.00 447,815.0000 316,142 338.71% 100.00%
Oct. 7, 2024 Leonard Braden Michael Not found J Common Stock 102076 $0.00 447,815.0000 316,142 29.52% 32.29%
Oct. 4, 2024 Mathers Edward T Not found A Stock Option (right to buy) 15300 $0.00 15,300.0000 316,142 9999.99% 4.84%
Oct. 4, 2024 Saccomano Nicholas A President and CEO A Class A Common Stock 4556 $0.00 4,556.0000 316,142 9999.99% 1.44%
Oct. 4, 2024 Saccomano Nicholas A President and CEO A Employee Stock Option (right to buy) 2359 $0.00 2,359.0000 316,142 9999.99% 0.75%
Oct. 4, 2024 Saccomano Nicholas A President and CEO A Employee Stock Option (right to buy) 1485 $0.00 1,485.0000 316,142 9999.99% 0.47%
Oct. 4, 2024 Saccomano Nicholas A President and CEO A Employee Stock Option (right to buy) 16898 $0.00 16,898.0000 316,142 9999.99% 5.35%
Oct. 4, 2024 Saccomano Nicholas A President and CEO A Employee Stock Option (right to buy) 8449 $0.00 8,449.0000 316,142 9999.99% 2.67%
Oct. 4, 2024 Saccomano Nicholas A President and CEO A Employee Stock Option (right to buy) 542232 $0.00 542,232.0000 316,142 9999.99% 100.00%
Oct. 4, 2024 Phillips Andrew John Not found A Stock Option (right to buy) 15300 $0.00 15,300.0000 316,142 9999.99% 4.84%
Oct. 4, 2024 Manke Isaac Not found A Stock Option (right to buy) 15300 $0.00 15,300.0000 316,142 9999.99% 4.84%
Oct. 4, 2024 Leverone Jason A. Chief Financial Officer A Class A Common Stock 16331 $0.00 16,331.0000 316,142 9999.99% 5.17%
Oct. 4, 2024 Leverone Jason A. Chief Financial Officer A Employee Stock Option (right to buy) 5781 $0.00 5,781.0000 316,142 9999.99% 1.83%
Oct. 4, 2024 Leverone Jason A. Chief Financial Officer A Employee Stock Option (right to buy) 5322 $0.00 5,322.0000 316,142 9999.99% 1.68%
Oct. 4, 2024 Leverone Jason A. Chief Financial Officer A Employee Stock Option (right to buy) 130611 $0.00 130,611.0000 316,142 9999.99% 41.31%
Oct. 4, 2024 Jansen Valerie Malyvanh Not found A Stock Option (right to buy) 15300 $0.00 15,300.0000 316,142 9999.99% 4.84%
Oct. 4, 2024 Hartley Dylan Chief Scientific Officer A Employee Stock Option (right to buy) 137603 $0.00 137,603.0000 316,142 9999.99% 43.53%
Oct. 4, 2024 GREY MICHAEL G Not found A Stock Option (right to buy) 15300 $0.00 15,300.0000 316,142 9999.99% 4.84%
Oct. 4, 2024 Carruthers R Michael Not found A Class A Common Stock 874 $0.00 874.0000 316,142 9999.99% 0.28%
Oct. 4, 2024 Carruthers R Michael Not found A Class A Common Stock 4065 $0.00 4,939.0000 316,142 465.10% 1.29%
Oct. 4, 2024 Carruthers R Michael Not found A Stock Option (right to buy) 1760 $0.00 1,760.0000 316,142 9999.99% 0.56%
Oct. 4, 2024 Carruthers R Michael Not found A Stock Option (right to buy) 1324 $0.00 1,324.0000 316,142 9999.99% 0.42%
Oct. 4, 2024 Carruthers R Michael Not found A Stock Option (right to buy) 15300 $0.00 15,300.0000 316,142 9999.99% 4.84%
Oct. 4, 2024 Agresta Samuel Chief Medical Officer A Employee Stock Option (right to buy) 18588 $0.00 18,588.0000 316,142 9999.99% 5.88%
Oct. 4, 2024 Agresta Samuel Chief Medical Officer A Employee Stock Option (right to buy) 131396 $0.00 131,396.0000 316,142 9999.99% 41.56%
Sept. 24, 2024 Leonard Braden Michael Not found P Common Stock 29600 $1.41 4,409,418.0000 283,817 0.68% 10.43%
Sept. 25, 2024 Leonard Braden Michael Not found P Common Stock 68746 $1.50 4,478,164.0000 283,817 1.56% 24.22%
Sept. 18, 2024 Leonard Braden Michael Not found P Common Stock 806 $1.40 4,379,818.0000 283,817 0.02% 0.28%
Sept. 17, 2024 Leonard Braden Michael Not found P Common Stock 55300 $1.36 4,379,012.0000 283,817 1.28% 19.48%
Sept. 13, 2024 Leonard Braden Michael Not found P Common Stock 150000 $1.31 4,150,965.0000 283,817 3.75% 52.85%
Sept. 12, 2024 Leonard Braden Michael Not found P Common Stock 36176 $1.40 4,000,965.0000 283,817 0.91% 12.75%
Sept. 16, 2024 Leonard Braden Michael Not found P Common Stock 172747 $1.37 4,323,712.0000 283,817 4.16% 60.87%
Aug. 13, 2024 Leonard Braden Michael Not found P Common Stock 171339 $1.39 3,864,302.0000 283,817 4.64% 60.37%
Aug. 14, 2024 Leonard Braden Michael Not found P Common Stock 100487 $1.41 3,964,789.0000 283,817 2.60% 35.41%
May 14, 2024 Leonard Braden Michael Not found P Common Stock 79281 $1.56 3,357,963.0000 283,817 2.42% 27.93%
May 14, 2024 Leonard Braden Michael Not found P Common Stock 335000 $1.54 3,692,963.0000 283,817 9.98% 100.00%
Aug. 28, 2023 Hall Ashley Chief Development Officer M Common Stock 15625 $1.80 55,225.0000 0 39.46% 0.00%
Aug. 28, 2023 Hall Ashley Chief Development Officer S Common Stock 15625 $6.28 39,600.0000 0 28.29% 0.00%
Aug. 28, 2023 Hall Ashley Chief Development Officer M Stock option (right to buy) 15625 $0.00 109,375.0000 0 12.50% 0.00%
July 26, 2023 GREY MICHAEL G Executive Chairman G Common Stock 50000 $0.00 628,846.0000 0 7.37% 0.00%
June 23, 2023 Novo Holdings A/S TenPercentOwner S Common Stock 100000 $7.10 3,330,337.0000 0 2.92% 0.00%
June 6, 2023 Seltzer Stacey Denenberg Director A Stock Option (right to buy) 17500 $0.00 17,500.0000 0 9999.99% 0.00%
June 6, 2023 O'Donnell Niall Director A Stock Option (right to buy) 17500 $0.00 17,500.0000 0 9999.99% 0.00%
June 6, 2023 Muralidhar Bali Director A Stock Option (right to buy) 17500 $0.00 17,500.0000 0 9999.99% 0.00%
June 6, 2023 GREY MICHAEL G Executive Chairman A Stock Option (right to buy) 17500 $0.00 17,500.0000 0 9999.99% 0.00%
June 6, 2023 Blunt Roshawn A. Director A Stock Option (right to buy) 14815 $0.00 14,815.0000 0 9999.99% 0.00%
June 6, 2023 Mathers Edward T Director A Stock Option (right to buy) 17500 $0.00 17,500.0000 0 50.00% 0.00%
June 6, 2023 Hoelscher Paul W. Director A Stock Option (right to buy) 17500 $0.00 17,500.0000 0 9999.99% 0.00%
June 6, 2023 Dube Eric M Director A Stock Option (right to buy) 17500 $0.00 17,500.0000 0 9999.99% 0.00%
May 8, 2023 O'Donnell Niall Director P Common Stock 125000 $8.00 2,188,713.0000 0 6.06% 0.00%