Monia Brett P, CEO of IONIS PHARMACEUTICALS INC ($IONS), sold common shares on the open market fourteen times in the last 365 days for a total of $35.6 million. Her most recent sale occurred on March 10, 2026. These IONIS insider sales rank 425th among 11,678 individual insiders, surpassing the average of $8.6 million and 6.4 transactions per person. Monia Brett P recorded no open market purchases in this period.
| Transaction Date | Company | Ticker | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 16512 | $75.47 | 260,253.0000 | 158,964,772 | 5.97% | 0.01% |
| March 9, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 1684 | $75.58 | 242,662.0000 | 158,964,772 | 0.69% | 0.00% |
| March 9, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 40822 | $0.00 | 107,632.0000 | 158,964,772 | 27.50% | 0.03% |
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 17591 | $76.34 | 242,662.0000 | 158,964,772 | 6.76% | 0.01% |
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 34103 | $60.89 | 276,765.0000 | 158,964,772 | 14.05% | 0.02% |
| March 9, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 73529 | $0.00 | 34,103.0000 | 158,964,772 | 68.32% | 0.05% |
| March 9, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 40822 | $60.89 | 295,803.0000 | 158,964,772 | 16.01% | 0.03% |
| March 9, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 73529 | $60.89 | 369,332.0000 | 158,964,772 | 24.86% | 0.05% |
| March 9, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 7382 | $74.11 | 361,950.0000 | 158,964,772 | 2.00% | 0.00% |
| March 9, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 117604 | $75.26 | 244,346.0000 | 158,964,772 | 32.49% | 0.07% |
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 34103 | $0.00 | 0.0000 | 158,964,772 | 100.00% | 0.02% |
| Feb. 27, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | J | Common Stock | 484 | $48.87 | 254,981.0000 | 158,964,772 | 0.19% | 0.00% |
| Feb. 6, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 29430 | $85.79 | 254,497.0000 | 158,964,772 | 10.37% | 0.02% |
| Jan. 29, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Common Stock | 122214 | $0.00 | 346,897.0000 | 158,964,772 | 54.39% | 0.08% |
| Jan. 30, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 62970 | $82.72 | 283,927.0000 | 158,964,772 | 18.15% | 0.04% |
| Jan. 15, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 89145 | $0.00 | 268,717.0000 | 158,964,772 | 49.64% | 0.06% |
| Jan. 15, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Restricted Stock Unit | 42705 | $0.00 | 205,719.0000 | 158,964,772 | 26.20% | 0.03% |
| Jan. 15, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Restricted Stock Unit | 89145 | $0.00 | 163,014.0000 | 158,964,772 | 35.35% | 0.06% |
| Jan. 15, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Performance Restricted Stock Units | 113880 | $0.00 | 744,081.0000 | 158,964,772 | 18.07% | 0.07% |
| Jan. 16, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 44034 | $74.82 | 224,683.0000 | 158,964,772 | 16.39% | 0.03% |
| Jan. 2, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Non-Qualified Stock Option (right to buy) | 85410 | $0.00 | 85,410.0000 | 158,964,772 | 9999.99% | 0.05% |
| Oct. 6, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 437 | $69.26 | 179,572.0000 | 158,964,772 | 0.24% | 0.00% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 31316 | $0.00 | 67,741.0000 | 158,964,772 | 31.61% | 0.02% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 31316 | $32.60 | 212,140.0000 | 158,964,772 | 17.32% | 0.02% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 27568 | $32.60 | 239,708.0000 | 158,964,772 | 13.00% | 0.02% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 59699 | $61.06 | 180,009.0000 | 158,964,772 | 24.90% | 0.04% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 27568 | $0.00 | 40,173.0000 | 158,964,772 | 40.70% | 0.02% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 42030 | $0.00 | 76,643.0000 | 158,964,772 | 35.42% | 0.03% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 102900 | $0.00 | 0.0000 | 158,964,772 | 100.00% | 0.06% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 102900 | $53.77 | 282,909.0000 | 158,964,772 | 57.16% | 0.06% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 16615 | $59.12 | 266,294.0000 | 158,964,772 | 5.87% | 0.01% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 42030 | $37.58 | 308,324.0000 | 158,964,772 | 15.78% | 0.03% |
| Sept. 3, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 127500 | $60.13 | 180,824.0000 | 158,964,772 | 41.35% | 0.08% |
| Aug. 29, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | J | Common Stock | 189 | $27.71 | 180,009.0000 | 158,964,772 | 0.11% | 0.00% |
| July 30, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 2432 | $32.60 | 182,252.0000 | 158,964,772 | 1.35% | 0.00% |
| July 30, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 2432 | $45.00 | 179,820.0000 | 158,964,772 | 1.33% | 0.00% |
| July 30, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 2432 | $0.00 | 99,057.0000 | 158,964,772 | 2.40% | 0.00% |
| July 11, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 1160 | $41.74 | 179,820.0000 | 158,964,772 | 0.64% | 0.00% |
| June 18, 2025 | COGNITION THERAPEUTICS INC | $CGTX | Monia Brett P | Director | A | Common Stock | 34000 | $0.00 | 48,500.0000 | 61,828,149 | 234.48% | 0.05% |
| March 11, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 140 | $32.32 | 180,980.0000 | 158,964,772 | 0.08% | 0.00% |
| Feb. 28, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | J | Common Stock | 437 | $28.21 | 181,120.0000 | 158,964,772 | 0.24% | 0.00% |
| Feb. 4, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 38843 | $31.65 | 180,683.0000 | 0 | 17.69% | 0.00% |
| Jan. 31, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 13242 | $32.45 | 219,526.0000 | 0 | 5.69% | 0.00% |
| Jan. 30, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Common Stock | 25372 | $0.00 | 232,768.0000 | 0 | 12.23% | 0.00% |
| Jan. 15, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Restricted Stock Unit | 73448 | $0.00 | 252,159.0000 | 0 | 22.56% | 0.00% |
| Jan. 15, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Performance Restricted Stock Units | 169950 | $0.00 | 630,201.0000 | 0 | 36.93% | 0.00% |
| Jan. 16, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 33445 | $32.63 | 207,396.0000 | 0 | 13.89% | 0.00% |
| Jan. 15, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 73448 | $0.00 | 240,841.0000 | 0 | 43.88% | 0.00% |
| Jan. 15, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Restricted Stock Unit | 129395 | $0.00 | 325,607.0000 | 0 | 65.95% | 0.00% |
| Jan. 2, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Non-Qualified Stock Option (right to buy) | 86263 | $0.00 | 86,263.0000 | 0 | 9999.99% | 0.00% |
| Nov. 12, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 6630 | $38.05 | 167,393.0000 | 0 | 3.81% | 0.00% |
| Aug. 30, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | J | Common Stock | 140 | $38.64 | 174,023.0000 | 0 | 0.08% | 0.00% |
| Feb. 2, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 23907 | $49.37 | 173,732.0000 | 0 | 12.10% | 0.00% |
| Feb. 2, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 23907 | $49.37 | 173,732.0000 | 0 | 12.10% | 0.00% |
| June 7, 2024 | COGNITION THERAPEUTICS INC | $CGTX | Monia Brett P | Director | A | Common Stock | 8500 | $0.00 | 14,500.0000 | 33,735,269 | 141.67% | 0.03% |
| June 7, 2024 | COGNITION THERAPEUTICS INC | $CGTX | Monia Brett P | Director | A | Stock Option (right to buy) | 8500 | $0.00 | 8,500.0000 | 33,735,269 | 9999.99% | 0.03% |
| Feb. 29, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | CEO Level 15 | J | Common Stock | 538 | $34.43 | 174,289.0000 | 0 | 0.31% | 0.00% |
| Feb. 16, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 387 | $44.49 | 173,751.0000 | 0 | 0.22% | 0.00% |
| Feb. 1, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Common Stock | 25372 | $0.00 | 177,223.0000 | 0 | 16.71% | 0.00% |
| Feb. 1, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Common Stock | 20416 | $0.00 | 197,639.0000 | 0 | 11.52% | 0.00% |
| Feb. 2, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 23501 | $49.37 | 174,138.0000 | 0 | 11.89% | 0.00% |
| Jan. 25, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 2285 | $51.75 | 151,851.0000 | 0 | 1.48% | 0.00% |
| Jan. 17, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 32059 | $50.42 | 154,136.0000 | 0 | 17.22% | 0.00% |
| Jan. 16, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 68084 | $0.00 | 186,195.0000 | 0 | 57.64% | 0.00% |
| Jan. 16, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Restricted Stock Unit | 68084 | $10.00 | 196,212.0000 | 0 | 25.76% | 0.00% |
| Jan. 15, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Performance Restricted Stock Units | 143550 | $0.00 | 460,251.0000 | 0 | 45.33% | 0.00% |
| Jan. 15, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Restricted Stock Unit | 87435 | $0.00 | 264,296.0000 | 0 | 49.44% | 0.00% |
| Jan. 2, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Non-Qualified Stock Option (right to buy) | 116580 | $0.00 | 116,580.0000 | 0 | 9999.99% | 0.00% |
| Dec. 20, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 6500 | $49.64 | 118,111.0000 | 0 | 5.22% | 0.00% |
| Dec. 21, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 17500 | $49.29 | 118,111.0000 | 0 | 12.90% | 0.00% |
| Dec. 20, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 6500 | $0.00 | 17,500.0000 | 0 | 27.08% | 0.00% |
| Dec. 21, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 17500 | $0.00 | 0.0000 | 0 | 100.00% | 0.00% |
| Dec. 21, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 17500 | $47.34 | 135,611.0000 | 0 | 14.82% | 0.00% |
| Dec. 20, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 6500 | $47.34 | 124,611.0000 | 0 | 5.50% | 0.00% |
| Dec. 14, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 9140 | $47.34 | 127,251.0000 | 0 | 7.74% | 0.00% |
| Dec. 14, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 14860 | $47.34 | 132,971.0000 | 0 | 12.58% | 0.00% |
| Dec. 14, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 14860 | $49.21 | 118,111.0000 | 0 | 11.18% | 0.00% |
| Dec. 14, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 9140 | $0.00 | 24,000.0000 | 0 | 27.58% | 0.00% |
| Dec. 14, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 9140 | $50.19 | 118,111.0000 | 0 | 7.18% | 0.00% |
| Dec. 14, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Non-Qualified Stock Option (right to buy) | 14860 | $0.00 | 33,140.0000 | 0 | 30.96% | 0.00% |
| Oct. 12, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 3770 | $46.00 | 118,111.0000 | 0 | 3.09% | 0.00% |
| Aug. 31, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | CEO Level 15 | J | Common Stock | 157 | $30.56 | 121,881.0000 | 0 | 0.13% | 0.00% |
| July 7, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 18650 | $42.25 | 121,724.0000 | 0 | 13.29% | 0.00% |
| May 22, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 2630 | $40.14 | 140,374.0000 | 0 | 1.84% | 0.00% |
| May 22, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 2301 | $40.13 | 143,004.0000 | 0 | 1.58% | 0.00% |
| Feb. 3, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Common Stock | 25372 | $0.00 | 169,956.0000 | 0 | 17.55% | 0.00% |
| Feb. 3, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Common Stock | 6511 | $0.00 | 127,374.0000 | 0 | 5.39% | 0.00% |
| Feb. 3, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Common Stock | 17210 | $0.00 | 144,584.0000 | 0 | 13.51% | 0.00% |
| Feb. 6, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 24651 | $40.69 | 145,305.0000 | 0 | 14.50% | 0.00% |
| Jan. 18, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | S | Common Stock | 25066 | $39.49 | 120,863.0000 | 0 | 17.18% | 0.00% |
| Jan. 17, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Common Stock | 57267 | $0.00 | 145,929.0000 | 0 | 64.59% | 0.00% |
| Jan. 17, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | M | Restricted Stock Unit | 57267 | $0.00 | 176,861.0000 | 0 | 24.46% | 0.00% |
| Jan. 15, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Restricted Stock Unit | 89005 | $0.00 | 234,128.0000 | 0 | 61.33% | 0.00% |
| Jan. 15, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Performance Restricted Stock Units | 146128 | $0.00 | 316,701.0000 | 0 | 85.67% | 0.00% |
| Jan. 3, 2023 | IONIS PHARMACEUTICALS INC | $IONS | Monia Brett P | Chief Executive Officer | A | Non-Qualified Stock Option (right to buy) | 118673 | $0.00 | 118,673.0000 | 0 | 9999.99% | 0.00% |