SEC Insider Transactions from Goff Brian.

Last updated: 2026-03-14 11:54 UTC | Total transactions: 63

Goff Brian, CEO of Agios Pharmaceuticals ($AGIO), sold shares on the open market eight times over the past year, totaling about $2.1 million. His most recent sale occurred on March 2, 2026. These sales rank 3,436th among 11,678 individual insiders in our database, where the average is $8.6 million across roughly 6.4 transactions. Brian made no open market purchases in this period.

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Transaction Date Company Ticker Insider Name Title Transaction Type Security Shares Price Shares Owned Following Total Shares Outstanding % of Owned % of Outstanding
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 8500 $0.00 151,603.0000 74,665,003 5.94% 0.01%
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 18000 $0.00 18,000.0000 74,665,003 50.00% 0.02%
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 8500 $0.00 0.0000 74,665,003 100.00% 0.01%
March 1, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer A Stock options (right to buy) 174000 $0.00 174,000.0000 74,665,003 9999.99% 0.23%
March 1, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer A Restricted stock units 48000 $0.00 48,000.0000 74,665,003 9999.99% 0.06%
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 5918 $28.96 164,548.0000 74,665,003 3.47% 0.01%
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 13000 $0.00 170,466.0000 74,665,003 8.26% 0.02%
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 8267 $28.96 157,466.0000 74,665,003 4.99% 0.01%
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 18000 $0.00 165,733.0000 74,665,003 12.18% 0.02%
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 3870 $28.96 147,733.0000 74,665,003 2.55% 0.01%
March 2, 2026 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 13000 $0.00 26,000.0000 74,665,003 33.33% 0.02%
Dec. 30, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Performance share units 12750 $0.00 0.0000 74,496,287,000 100.00% 0.00%
Dec. 30, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 6230 $27.09 143,103.0000 74,496,287,000 4.17% 0.00%
Dec. 30, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 12750 $0.00 149,333.0000 74,496,287,000 9.33% 0.00%
Dec. 30, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 12473 $27.09 136,583.0000 74,496,287,000 8.37% 0.00%
Dec. 30, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 25528 $0.00 149,056.0000 74,496,287,000 20.67% 0.00%
Dec. 30, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Performance share units 25528 $0.00 25,528.0000 74,496,287,000 50.00% 0.00%
Aug. 8, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 22691 $0.00 134,613.0000 74,254,956,000 20.27% 0.00%
Aug. 8, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 11085 $36.67 123,528.0000 74,254,956,000 8.23% 0.00%
Aug. 8, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 22691 $0.00 0.0000 74,254,956,000 100.00% 0.00%
June 24, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Performance share units 25527 $0.00 51,056.0000 74,103,192,000 33.33% 0.00%
June 24, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 25527 $0.00 117,872.0000 74,103,192,000 27.64% 0.00%
June 24, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 12471 $33.54 105,401.0000 74,103,192,000 10.58% 0.00%
June 24, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 12750 $0.00 118,151.0000 74,103,192,000 12.10% 0.00%
June 24, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 6229 $33.54 111,922.0000 74,103,192,000 5.27% 0.00%
June 24, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Performance share units 12750 $0.00 12,750.0000 74,103,192,000 50.00% 0.00%
June 11, 2025 Intellia Therapeutics, Inc. $NTLA Goff Brian Not found A Common Stock 8000 $0.00 23,409.0000 103,517,460 51.92% 0.01%
June 11, 2025 Intellia Therapeutics, Inc. $NTLA Goff Brian Not found A Stock Option (right to buy) 11450 $0.00 11,450.0000 103,517,460 9999.99% 0.01%
March 1, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 8500 $0.00 87,292.0000 73,372,696,000 10.79% 0.00%
March 3, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 4153 $35.54 83,139.0000 73,372,696,000 4.76% 0.00%
March 1, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 18000 $0.00 101,139.0000 73,372,696,000 21.65% 0.00%
March 1, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 18000 $0.00 36,000.0000 73,372,696,000 33.33% 0.00%
March 1, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer A Restricted stock units 39000 $0.00 39,000.0000 73,372,696,000 9999.99% 0.00%
March 1, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer A Stock options (right to buy) 142500 $0.00 142,500.0000 73,372,696,000 9999.99% 0.00%
March 3, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 8794 $35.54 92,345.0000 73,372,696,000 8.69% 0.00%
March 1, 2025 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 8500 $0.00 8,500.0000 73,372,696,000 50.00% 0.00%
Aug. 8, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 22691 $0.00 89,883.0000 73,091,490,000 33.77% 0.00%
Aug. 8, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 22691 $0.00 22,691.0000 73,091,490,000 50.00% 0.00%
Aug. 8, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 11091 $42.75 78,792.0000 73,091,490,000 12.34% 0.00%
June 13, 2024 Intellia Therapeutics, Inc. $NTLA Goff Brian Not found A Common Stock 15409 $0.00 15,409.0000 0 9999.99% 0.00%
June 13, 2024 Intellia Therapeutics, Inc. $NTLA Goff Brian Not found A Stock Option (right to buy) 22297 $0.00 22,297.0000 0 9999.99% 0.00%
June 5, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 25527 $0.00 79,307.0000 72,967,922,000 47.47% 0.00%
June 5, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Performance share units 25527 $0.00 76,583.0000 72,967,922,000 25.00% 0.00%
June 5, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 12115 $48.84 67,192.0000 72,967,922,000 15.28% 0.00%
March 1, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer A Stock options (right to buy) 195500 $0.00 195,500.0000 72,161,489,000 9999.99% 0.00%
March 1, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 8500 $0.00 17,000.0000 72,161,489,000 33.33% 0.00%
March 1, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer A Restricted stock units 54000 $0.00 54,000.0000 72,161,489,000 9999.99% 0.00%
March 5, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 4156 $32.57 53,780.0000 72,161,489,000 7.17% 0.00%
March 1, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 8500 $0.00 57,936.0000 72,161,489,000 17.19% 0.00%
Jan. 24, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 7635 $21.64 49,436.0000 72,161,489,000 13.38% 0.00%
Jan. 20, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Performance share units 17018 $0.00 102,110.0000 72,161,489,000 14.29% 0.00%
Jan. 20, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 17018 $0.00 57,071.0000 72,161,489,000 42.49% 0.00%
Jan. 9, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 12066 $22.99 40,053.0000 72,161,489,000 23.15% 0.00%
Jan. 5, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Performance share units 25527 $0.00 119,128.0000 72,161,489,000 17.65% 0.00%
Jan. 5, 2024 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 25527 $0.00 52,119.0000 72,161,489,000 96.00% 0.00%
Aug. 8, 2023 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 22691 $0.00 36,770.0000 71,256,118 161.17% 0.03%
Aug. 8, 2023 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Restricted stock units 22691 $0.00 45,382.0000 71,256,118 33.33% 0.03%
Aug. 8, 2023 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 10178 $25.48 26,592.0000 71,256,118 27.68% 0.01%
June 28, 2023 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Common stock 25528 $0.00 25,528.0000 71,256,118 9999.99% 0.04%
June 30, 2023 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer S Common stock 11449 $28.36 14,079.0000 71,256,118 44.85% 0.02%
June 28, 2023 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer M Performance share units 25528 $0.00 144,655.0000 71,256,118 15.00% 0.04%
March 1, 2023 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer A Stock options (right to buy) 94500 $0.00 94,500.0000 71,256,118 9999.99% 0.13%
March 1, 2023 AGIOS PHARMACEUTICALS, INC. $AGIO Goff Brian Chief Executive Officer A Restricted stock units 25500 $0.00 25,500.0000 71,256,118 9999.99% 0.04%