Smith Hunter C, Chief Financial Officer of Rhythm Pharmaceuticals, Inc. ($RYTM), sold shares on the open market thirty times in the last 365 days for a total of nearly $9.8 million. His most recent sale occurred on February 19, 2026. These $RYTM insider sales rank 1,151st among over 11,600 individual insiders in our database, where the average is $8.6 million across about six transactions. Smith Hunter C made no open market purchases during this period.
| Transaction Date | Company | Ticker | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| March 2, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Options (Right to Buy) | 6099 | $0.00 | 91,401.0000 | 64,984,361 | 6.26% | 0.01% |
| March 2, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 6099 | $6.80 | 116,611.0000 | 64,984,361 | 5.52% | 0.01% |
| Feb. 17, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 200 | $103.84 | 114,897.0000 | 64,984,361 | 0.17% | 0.00% |
| Feb. 17, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1200 | $99.42 | 117,266.0000 | 64,984,361 | 1.01% | 0.00% |
| Feb. 17, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 200 | $100.52 | 117,066.0000 | 64,984,361 | 0.17% | 0.00% |
| Feb. 17, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 900 | $101.70 | 116,166.0000 | 64,984,361 | 0.77% | 0.00% |
| Feb. 17, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1069 | $103.00 | 115,097.0000 | 64,984,361 | 0.92% | 0.00% |
| Feb. 19, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 585 | $103.28 | 110,512.0000 | 64,984,361 | 0.53% | 0.00% |
| Feb. 19, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 800 | $102.10 | 111,097.0000 | 64,984,361 | 0.71% | 0.00% |
| Feb. 19, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1692 | $100.92 | 111,897.0000 | 64,984,361 | 1.49% | 0.00% |
| Feb. 19, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1308 | $100.27 | 113,589.0000 | 64,984,361 | 1.14% | 0.00% |
| Feb. 11, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Restricted Stock Units | 25000 | $0.00 | 25,000.0000 | 64,984,361 | 9999.99% | 0.04% |
| Feb. 11, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Stock Options (Right to Buy) | 37500 | $0.00 | 37,500.0000 | 64,984,361 | 9999.99% | 0.06% |
| Feb. 10, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 700 | $103.68 | 122,924.0000 | 64,984,361 | 0.57% | 0.00% |
| Feb. 10, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1913 | $102.66 | 123,624.0000 | 64,984,361 | 1.52% | 0.00% |
| Feb. 10, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 100 | $104.76 | 122,824.0000 | 64,984,361 | 0.08% | 0.00% |
| Feb. 11, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 2266 | $98.37 | 120,558.0000 | 64,984,361 | 1.84% | 0.00% |
| Feb. 11, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 400 | $99.44 | 120,158.0000 | 64,984,361 | 0.33% | 0.00% |
| Feb. 11, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 100 | $100.85 | 120,058.0000 | 64,984,361 | 0.08% | 0.00% |
| Feb. 12, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 292 | $96.26 | 119,766.0000 | 64,984,361 | 0.24% | 0.00% |
| Feb. 12, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 400 | $97.67 | 119,366.0000 | 64,984,361 | 0.33% | 0.00% |
| Feb. 12, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 800 | $98.99 | 118,566.0000 | 64,984,361 | 0.67% | 0.00% |
| Feb. 12, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 100 | $100.10 | 118,466.0000 | 64,984,361 | 0.08% | 0.00% |
| Feb. 5, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 3381 | $106.06 | 125,537.0000 | 64,984,361 | 2.62% | 0.01% |
| Feb. 4, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 747 | $107.67 | 128,918.0000 | 64,984,361 | 0.58% | 0.00% |
| Feb. 4, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1000 | $106.60 | 129,665.0000 | 64,984,361 | 0.77% | 0.00% |
| Feb. 4, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1500 | $104.74 | 130,665.0000 | 64,984,361 | 1.13% | 0.00% |
| Feb. 1, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 26000 | $0.00 | 142,915.0000 | 64,984,361 | 22.24% | 0.04% |
| Feb. 1, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 10413 | $0.00 | 31,237.0000 | 64,984,361 | 25.00% | 0.02% |
| Feb. 1, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 6600 | $0.00 | 13,200.0000 | 64,984,361 | 33.33% | 0.01% |
| Feb. 1, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 4925 | $0.00 | 4,925.0000 | 64,984,361 | 50.00% | 0.01% |
| Feb. 1, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 4062 | $0.00 | 0.0000 | 64,984,361 | 100.00% | 0.01% |
| Feb. 1, 2026 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | F | Common Stock | 10750 | $108.99 | 132,165.0000 | 64,984,361 | 7.52% | 0.02% |
| Aug. 12, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 24611 | $96.33 | 116,915.0000 | 63,684,359 | 17.39% | 0.04% |
| Aug. 13, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Options (Right to Buy) | 3477 | $0.00 | 0.0000 | 63,684,359 | 100.00% | 0.01% |
| Aug. 12, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Options (Right to Buy) | 24611 | $0.00 | 3,477.0000 | 63,684,359 | 87.62% | 0.04% |
| Aug. 13, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 3477 | $96.00 | 116,915.0000 | 63,684,359 | 2.89% | 0.01% |
| Aug. 13, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 3477 | $6.88 | 120,392.0000 | 63,684,359 | 2.97% | 0.01% |
| Aug. 12, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 24611 | $6.88 | 141,526.0000 | 63,684,359 | 21.05% | 0.04% |
| July 9, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 17113 | $75.38 | 141,922.0000 | 63,684,359 | 10.76% | 0.03% |
| July 9, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1607 | $76.17 | 140,315.0000 | 63,684,359 | 1.13% | 0.00% |
| July 9, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 42120 | $6.88 | 159,035.0000 | 63,684,359 | 36.03% | 0.07% |
| July 9, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 23400 | $84.50 | 116,915.0000 | 63,684,359 | 16.68% | 0.04% |
| July 9, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Options (Right to Buy) | 42120 | $0.00 | 28,088.0000 | 63,684,359 | 59.99% | 0.07% |
| July 7, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 6986 | $6.88 | 116,915.0000 | 63,684,359 | 6.36% | 0.01% |
| July 7, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Options (Right to Buy) | 6986 | $0.00 | 70,208.0000 | 63,684,359 | 9.05% | 0.01% |
| May 30, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 23400 | $6.88 | 133,329.0000 | 63,059,165 | 21.29% | 0.04% |
| May 30, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 4407 | $60.93 | 128,922.0000 | 63,059,165 | 3.31% | 0.01% |
| May 30, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 18993 | $61.52 | 109,929.0000 | 63,059,165 | 14.73% | 0.03% |
| May 30, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Options (Right to Buy) | 23400 | $0.00 | 77,194.0000 | 63,059,165 | 23.26% | 0.04% |
| Feb. 14, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Restricted Stock Units | 41650 | $0.00 | 41,650.0000 | 60,995,204 | 9999.99% | 0.07% |
| Feb. 16, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 6600 | $0.00 | 112,144.0000 | 60,995,204 | 6.25% | 0.01% |
| Feb. 19, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 2215 | $57.22 | 109,929.0000 | 60,995,204 | 1.98% | 0.00% |
| Feb. 14, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Stock Options (Right to Buy) | 62500 | $0.00 | 62,500.0000 | 60,995,204 | 9999.99% | 0.10% |
| Feb. 16, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 6600 | $0.00 | 19,800.0000 | 60,995,204 | 25.00% | 0.01% |
| Feb. 12, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 12 | $56.22 | 105,544.0000 | 60,995,204 | 0.01% | 0.00% |
| Feb. 12, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 739 | $56.39 | 105,556.0000 | 60,995,204 | 0.70% | 0.00% |
| Feb. 9, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 4062 | $0.00 | 4,062.0000 | 60,995,204 | 50.00% | 0.01% |
| Feb. 9, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 4062 | $0.00 | 105,248.0000 | 60,995,204 | 4.01% | 0.01% |
| Feb. 11, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 2343 | $0.00 | 107,591.0000 | 60,995,204 | 2.23% | 0.00% |
| Feb. 11, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1291 | $57.51 | 106,300.0000 | 60,995,204 | 1.20% | 0.00% |
| Feb. 11, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 5 | $57.53 | 106,295.0000 | 60,995,204 | 0.00% | 0.00% |
| Feb. 11, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 2343 | $0.00 | 0.0000 | 60,995,204 | 100.00% | 0.00% |
| Feb. 1, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 4925 | $0.00 | 9,850.0000 | 60,995,204 | 33.33% | 0.01% |
| Feb. 1, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 4925 | $0.00 | 102,864.0000 | 60,995,204 | 5.03% | 0.01% |
| Feb. 4, 2025 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1678 | $59.43 | 101,186.0000 | 60,995,204 | 1.63% | 0.00% |
| March 19, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 15515 | $39.22 | 97,939.0000 | 57,673,128 | 13.68% | 0.03% |
| Feb. 16, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Restricted Stock Units | 26400 | $0.00 | 26,400.0000 | 57,673,128 | 9999.99% | 0.05% |
| Feb. 16, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Common Stock | 33750 | $0.00 | 113,454.0000 | 57,673,128 | 42.34% | 0.06% |
| Feb. 16, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Stock Option (Right to Buy) | 80400 | $0.00 | 80,400.0000 | 57,673,128 | 9999.99% | 0.14% |
| Feb. 13, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 709 | $49.82 | 79,704.0000 | 57,673,128 | 0.88% | 0.00% |
| Feb. 11, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 2344 | $0.00 | 2,343.0000 | 57,673,128 | 50.01% | 0.00% |
| Feb. 9, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 4063 | $0.00 | 8,124.0000 | 57,673,128 | 33.34% | 0.01% |
| Feb. 12, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1209 | $51.38 | 80,413.0000 | 57,673,128 | 1.48% | 0.00% |
| Feb. 11, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 2344 | $0.00 | 81,622.0000 | 57,673,128 | 2.96% | 0.00% |
| Feb. 9, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 4063 | $0.00 | 79,278.0000 | 57,673,128 | 5.40% | 0.01% |
| Feb. 1, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 4925 | $0.00 | 76,831.0000 | 57,673,128 | 6.85% | 0.01% |
| Feb. 1, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 4925 | $0.00 | 14,775.0000 | 57,673,128 | 25.00% | 0.01% |
| Feb. 1, 2024 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1616 | $45.06 | 75,215.0000 | 57,673,128 | 2.10% | 0.00% |
| Dec. 29, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 10500 | $6.88 | 71,906.0000 | 57,874,960 | 17.10% | 0.02% |
| Dec. 29, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Option (Right to Buy) | 10500 | $0.00 | 100,594.0000 | 57,874,960 | 9.45% | 0.02% |
| Dec. 5, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Option (Right to Buy) | 7026 | $0.00 | 131,094.0000 | 57,874,960 | 5.09% | 0.01% |
| Dec. 5, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 7026 | $6.88 | 68,432.0000 | 57,874,960 | 11.44% | 0.01% |
| Dec. 5, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 7026 | $35.06 | 61,406.0000 | 57,874,960 | 10.27% | 0.01% |
| Dec. 6, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 20000 | $6.88 | 81,406.0000 | 57,874,960 | 32.57% | 0.03% |
| Dec. 6, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Option (Right to Buy) | 20000 | $0.00 | 111,094.0000 | 57,874,960 | 15.26% | 0.03% |
| Dec. 6, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 20000 | $40.00 | 61,406.0000 | 57,874,960 | 24.57% | 0.03% |
| Nov. 24, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 10974 | $6.88 | 72,380.0000 | 57,874,960 | 17.87% | 0.02% |
| Nov. 24, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Option (Right to Buy) | 10974 | $0.00 | 138,120.0000 | 57,874,960 | 7.36% | 0.02% |
| Nov. 24, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 10974 | $35.02 | 61,406.0000 | 57,874,960 | 15.16% | 0.02% |
| Nov. 14, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 12000 | $30.38 | 61,406.0000 | 57,874,960 | 16.35% | 0.02% |
| Nov. 14, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 12000 | $6.88 | 73,406.0000 | 57,874,960 | 19.54% | 0.02% |
| Nov. 14, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Option (Right to Buy) | 12000 | $0.00 | 149,094.0000 | 57,874,960 | 7.45% | 0.02% |
| June 22, 2023 | Spyre Therapeutics, Inc. | $SYRE | Smith Hunter C | Director | A | Stock Option (right to buy) | 1950000 | $0.00 | 1,950,000.0000 | 0 | 9999.99% | 0.00% |
| June 16, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Stock Option (right to buy) | 2000 | $0.00 | 161,094.0000 | 56,708,975 | 1.23% | 0.00% |
| June 16, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 2000 | $6.88 | 61,406.0000 | 56,708,975 | 3.37% | 0.00% |
| Feb. 9, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1413 | $27.51 | 57,764.0000 | 52,120,701 | 2.39% | 0.00% |
| Feb. 11, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 2344 | $0.00 | 60,108.0000 | 52,120,701 | 4.06% | 0.00% |
| Feb. 14, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 702 | $26.87 | 59,406.0000 | 52,120,701 | 1.17% | 0.00% |
| Feb. 11, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 2344 | $0.00 | 4,687.0000 | 52,120,701 | 33.34% | 0.00% |
| Feb. 9, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Common Stock | 4063 | $0.00 | 59,177.0000 | 52,120,701 | 7.37% | 0.01% |
| Feb. 9, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | M | Restricted Stock Units | 4063 | $0.00 | 12,187.0000 | 52,120,701 | 25.00% | 0.01% |
| Feb. 9, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | S | Common Stock | 1398 | $27.66 | 57,779.0000 | 52,120,701 | 2.36% | 0.00% |
| Feb. 1, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Stock Option (Right to Buy) | 53600 | $0.00 | 53,600.0000 | 52,120,701 | 9999.99% | 0.10% |
| Feb. 1, 2023 | RHYTHM PHARMACEUTICALS, INC. | $RYTM | Smith Hunter C | Chief Financial Officer | A | Restricted Stock Units | 19700 | $0.00 | 19,700.0000 | 52,120,701 | 9999.99% | 0.04% |