Ryan J. Watts, President and CEO of Denali Therapeutics Inc. ($DNLI), sold about $8 million worth of company shares in two open market transactions over the last year. His most recent sale occurred on January 6, 2026. These sales rank 1,345th among 11,678 individual insiders by total value sold, below the average of $8.6 million across about six transactions per insider. Watts made no open market purchases during this period.
| Transaction Date | Company | Ticker | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Jan. 6, 2026 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 35198 | $16.50 | 2,449,437.0000 | 172,421,492 | 1.42% | 0.02% |
| Jan. 3, 2026 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | A | Stock Option (right to buy) | 236880 | $0.00 | 236,880.0000 | 172,421,492 | 9999.99% | 0.14% |
| Jan. 3, 2026 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | A | Common Stock | 78960 | $0.00 | 2,484,635.0000 | 172,421,492 | 3.28% | 0.05% |
| Sept. 3, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | G | Common Stock | 50000 | $0.00 | 2,405,675.0000 | 164,473,772 | 2.04% | 0.03% |
| July 9, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | M | Stock Option (right to buy) | 40000 | $0.00 | 20,369.0000 | 164,473,772 | 66.26% | 0.02% |
| July 9, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | M | Common Stock | 455282 | $0.68 | 2,910,957.0000 | 164,473,772 | 18.54% | 0.28% |
| July 9, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | M | Common Stock | 40000 | $5.28 | 2,950,957.0000 | 164,473,772 | 1.37% | 0.02% |
| July 9, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 495282 | $15.00 | 2,455,675.0000 | 164,473,772 | 16.78% | 0.30% |
| July 9, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | M | Stock Option (right to buy) | 455282 | $0.00 | 622,809.0000 | 164,473,772 | 42.23% | 0.28% |
| Jan. 7, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 7650 | $20.81 | 2,455,675.0000 | 164,473,772 | 0.31% | 0.00% |
| Jan. 6, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 29266 | $20.22 | 2,463,325.0000 | 164,473,772 | 1.17% | 0.02% |
| Jan. 3, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | A | Common Stock | 54180 | $0.00 | 2,492,591.0000 | 164,473,772 | 2.22% | 0.03% |
| Jan. 3, 2025 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | A | Stock Option (right to buy) | 162540 | $0.00 | 162,540.0000 | 164,473,772 | 9999.99% | 0.10% |
| Oct. 18, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | M | Common Stock | 40000 | $0.68 | 2,478,411.0000 | 169,456,988 | 1.64% | 0.02% |
| Oct. 18, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 40000 | $27.69 | 2,438,411.0000 | 169,456,988 | 1.61% | 0.02% |
| Oct. 18, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | M | Stock Option (right to buy) | 40000 | $0.00 | 1,078,091.0000 | 169,456,988 | 3.58% | 0.02% |
| Aug. 20, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 2260 | $23.79 | 2,438,411.0000 | 137,370,897 | 0.09% | 0.00% |
| March 29, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | G | Common Stock | 40000 | $0.00 | 2,440,671.0000 | 137,370,897 | 1.61% | 0.03% |
| Feb. 13, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 9589 | $17.29 | 2,480,671.0000 | 137,370,897 | 0.39% | 0.01% |
| Jan. 9, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 7818 | $19.78 | 2,490,260.0000 | 137,370,897 | 0.31% | 0.01% |
| Jan. 5, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | S | Common Stock | 17483 | $19.43 | 2,498,078.0000 | 137,370,897 | 0.69% | 0.01% |
| Jan. 3, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | A | Stock Option (right to buy) | 268560 | $0.00 | 268,560.0000 | 137,370,897 | 9999.99% | 0.20% |
| Jan. 3, 2024 | Denali Therapeutics Inc. | $DNLI | Watts Ryan J. | President and CEO | A | Common Stock | 89520 | $0.00 | 2,515,561.0000 | 137,370,897 | 3.69% | 0.07% |