Jenne Kyle, EVP and Chief Global Product Strategy Officer at Ionis Pharmaceuticals ($IONS), sold about $3.1 million in company shares across four open market transactions in the past year. Her latest sale occurred on March 10, 2026. These sales rank her 2,687th among 11,678 insiders by total value, trailing the average of $8.6 million over 6.4 transactions. She reported no open market purchases during this period.
| Transaction Date | Company | Ticker | Insider Name | Title | Transaction Type | Security | Shares | Price | Shares Owned Following | Total Shares Outstanding | % of Owned | % of Outstanding |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | M | Common Stock | 32602 | $46.10 | 48,991.0000 | 158,964,772 | 198.93% | 0.02% |
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | M | Non-Qualified Stock Option (right to buy) | 32602 | $0.00 | 32,601.0000 | 158,964,772 | 50.00% | 0.02% |
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | M | Non-Qualified Stock Option (right to buy) | 4675 | $0.00 | 14,025.0000 | 158,964,772 | 25.00% | 0.00% |
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | M | Common Stock | 4675 | $34.69 | 16,389.0000 | 158,964,772 | 39.91% | 0.00% |
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | S | Common Stock | 16086 | $76.30 | 11,714.0000 | 158,964,772 | 57.86% | 0.01% |
| March 10, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | S | Common Stock | 21191 | $75.50 | 27,800.0000 | 158,964,772 | 43.25% | 0.01% |
| Jan. 16, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | S | Common Stock | 1823 | $75.96 | 16,389.0000 | 158,964,772 | 10.01% | 0.00% |
| Jan. 15, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | M | Common Stock | 7013 | $0.00 | 18,212.0000 | 158,964,772 | 62.62% | 0.00% |
| Jan. 15, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | A | Performance Restricted Stock Units | 25800 | $0.00 | 44,500.0000 | 158,964,772 | 137.97% | 0.02% |
| Jan. 15, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | A | Restricted Stock Unit | 9675 | $0.00 | 37,725.0000 | 158,964,772 | 34.49% | 0.01% |
| Jan. 15, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | M | Restricted Stock Unit | 7013 | $0.00 | 29,664.0000 | 158,964,772 | 19.12% | 0.00% |
| Jan. 2, 2026 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | A | Non-Qualified Stock Option (right to buy) | 19350 | $0.00 | 19,350.0000 | 158,964,772 | 9999.99% | 0.01% |
| April 16, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | S | Common Stock | 3016 | $28.36 | 11,199.0000 | 158,964,772 | 21.22% | 0.00% |
| April 15, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | M | Restricted Stock Unit | 12226 | $0.00 | 36,677.0000 | 158,964,772 | 25.00% | 0.01% |
| April 15, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | M | Common Stock | 12226 | $0.00 | 14,215.0000 | 158,964,772 | 614.68% | 0.01% |
| Jan. 15, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | A | Restricted Stock Unit | 28050 | $0.00 | 28,050.0000 | 0 | 9999.99% | 0.00% |
| Jan. 15, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | A | Performance Restricted Stock Units | 18700 | $0.00 | 18,700.0000 | 0 | 9999.99% | 0.00% |
| Jan. 2, 2025 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | A | Non-Qualified Stock Option (right to buy) | 18700 | $0.00 | 18,700.0000 | 0 | 9999.99% | 0.00% |
| Feb. 26, 2024 | IONIS PHARMACEUTICALS INC | $IONS | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | A | Non-Qualified Stock Option (right to buy) | 65203 | $0.00 | 65,203.0000 | 0 | 9999.99% | 0.00% |